Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing sales7@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Nitro-1,4-Benzenediamine Sulfate

    • Product Name 2-Nitro-1,4-Benzenediamine Sulfate
    • Alias 2-Nitro-p-phenylenediamine sulfate
    • Einecs 258-952-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    619568

    Product Name 2-Nitro-1,4-Benzenediamine Sulfate
    Synonym 2-Nitro-p-phenylenediamine sulfate
    Cas Number 52645-66-4
    Chemical Formula C6H8N4O6S
    Molecular Weight 280.22 g/mol
    Appearance Yellow to brown crystalline powder
    Solubility Soluble in water
    Melting Point Decomposes before melting
    Odor Odorless
    Storage Temperature Store at room temperature, keep container tightly closed
    Purity Typically >98%
    Application Hair dye intermediate, chemical reagent
    Hazard Classification Harmful if swallowed or in contact with skin

    As an accredited 2-Nitro-1,4-Benzenediamine Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a sealed, amber glass bottle containing 100 grams of 2-Nitro-1,4-Benzenediamine Sulfate, labeled with safety instructions.
    Shipping 2-Nitro-1,4-Benzenediamine Sulfate is shipped in tightly sealed containers to prevent moisture and contamination. It should be packaged according to regulatory guidelines for hazardous chemicals, typically with proper labeling and documentation. Transport must comply with local, national, and international regulations, including appropriate handling and storage requirements for safety.
    Storage 2-Nitro-1,4-Benzenediamine Sulfate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and acids. Protect from moisture and light. Ensure the storage area is clearly labeled and access is restricted to trained personnel. Follow all relevant safety and regulatory guidelines for hazardous chemicals.
    Application of 2-Nitro-1,4-Benzenediamine Sulfate

    Applications of 2-Nitro-1,4-Benzenediamine Sulfate in Industrial Manufacturing

    2-Nitro-1,4-Benzenediamine Sulfate is a key intermediate in industrial processes where high standards for purity, consistency, and traceability are critical. As an established manufacturer, we supply this material to a select group of industries where its specific functional groups make it indispensable in controlled synthesis, notably in hair dye, organic pigment, specialty polymer, and fine chemical sectors. Below we outline the principal application scenarios, including real-world compliance, dosage, process integration, and end-products.

    1. Oxidative Hair Dye Intermediate

    In advanced professional and mass-market hair color formulations, our product enables chemists to achieve red, purple, and deep brown shades through oxidative coupling reactions. The molecule’s electron-donating and electron-withdrawing substituents allow for precise coloration and shade stability. Manufacturers select this intermediate for permanent and demi-permanent products requiring reliable color fastening and low allergen risk.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009 Annex III (hair dye restrictions)
    • US FDA 21 CFR Part 73.2647 (hair dye ingredient listing)
    • Japanese Standards of Quasi-drug Ingredients (JSQI)

    Typical usage ratio

    • Usually incorporated at 0.1%–2.0% in final coloring cream, adjusted based on desired depth: high-concentration use in red shades, lower ratios in darker tints.

    Downstream process integration

    • Added during the colorant premix phase before emulsification; pre-diluted in water or glycols to ensure homogeneous dispersion, followed by oxidation with hydrogen peroxide during end-user application.

    Final product types

    • Permanent (oxidative) hair color creams
    • Long-lasting hair gels and mousses
    • Salon-exclusive cream developers for professional colorists

    2. Aromatic Dye and Pigment Synthesis

    Specialty pigment manufacturers incorporate this compound for the targeted synthesis of azo and anthraquinone derivatives, used in printing inks and plastics requiring thermal stability and light fastness. The nitro-diamine structure facilitates diazotization and coupling steps, allowing precision in producing high-purity colorants with controlled crystal morphology.

    Industry compliance standards

    • EN 71-3 Safety of Toys (migration of certain elements in pigments)
    • REACH Regulation (EC) No 1907/2006 Registration, Evaluation, and Authorization of Chemicals
    • ISO 787-24 (general methods of test for pigments and extenders)

    Typical usage ratio

    • Usually 0.2%–1.0% of total pigment batch; dosage depends on target shade intensity, particle size specification, and required fastness properties.

    Downstream process integration

    • Diazotized in aqueous medium with sodium nitrite, then coupled with appropriate aromatic compounds, followed by isolation, drying, and milling of the pigment cake.

    Final product types

    • Offset and flexographic printing inks
    • High-color-stability plastic masterbatches
    • Industrial coatings for metal and plastic substrates

    3. High-Performance Polybenzimidazole Fiber Production

    Producers of technical fibers employed in aerospace, firefighting, and filtration rely on this diamine derivative as a building block for polybenzimidazole (PBI) polymers. The nitro functionality ensures controllable reactivity, enabling the formation of heat-resistant, non-flammable fibers that meet rigorous performance criteria for demanding safety applications.

    Industry compliance standards

    • NFPA 1971 (Standard on Protective Ensembles for Structural Fire Fighting and Proximity Fire Fighting)
    • ASTM D7016 (Standard Terminology Relating to Nonwoven Fabrics)
    • REACH SVHC (for monomer use and residual content control)

    Typical usage ratio

    • Feed ratio between 0.7 and 1.3 parts per 1 part co-diamine, proportion tailored to intrinsic viscosity target and flame retardancy benchmarks.

    Downstream process integration

    • Reacted with aromatic dicarboxylic acids in high-boiling solvents by polycondensation at elevated temperatures, followed by spinning, washing, and further post-curing of fiber filaments.

    Final product types

    • PBI staple fibers and continuous filaments
    • Firefighter turnout gear and heat-resistant textiles
    • High-grade filter media for chemical processing

    4. Fine Chemical Intermediate for Pharmaceutical Precursors

    In pharmaceutical manufacturing, this substance serves as a precursor to specific heterocyclic intermediates that enter active pharmaceutical ingredient (API) synthesis routes. Its defined substitution pattern allows medicinal chemists to construct ring systems for antiparasitic, antituberculosis, or antimicrobial agents where functional selectivity is required by the target molecule’s pharmacophore.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) for API intermediates (ICH Q7)
    • USP/NF monograph (where applicable, for process validation)
    • EDQM CEP (Certificate of Suitability of Monographs of the European Pharmacopoeia, where relevant)

    Typical usage ratio

    • Typical intermediate coupling use at 0.5–1.5 equivalents in relation to primary nucleophile, based on the stoichiometry of the API synthesis step.

    Downstream process integration

    • Introduced during the construction of fused heteroaromatic rings via reduction and cyclization or as a nitro-activated substrate for subsequent functional group interconversion, requiring careful monitoring of impurity carryover to meet regulatory thresholds.

    Final product types

    • Registered small-molecule pharmaceutical intermediates
    • Process development APIs used in clinical-stage research
    • Building blocks for custom-synthesized drug leads
    Free Quote

    Competitive 2-Nitro-1,4-Benzenediamine Sulfate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Nitro-1,4-Benzenediamine Sulfate: A Closer Look from the Manufacturer’s View

    Understanding 2-Nitro-1,4-Benzenediamine Sulfate as a Chemical Raw Material

    Our experience in producing 2-Nitro-1,4-Benzenediamine Sulfate springs from decades of working alongside formulators in hair color, dye intermediates, and specialty materials. This compound, also known as para-amino-2-nitroaniline sulfate, carries a signature in its stability and reactivity, and those features shape its value in commercial applications. Every kilogram we supply comes with attention to purity levels, moisture control, and crystalline consistency, driven by feedback from customers who use the product in complex chemical syntheses.

    The Specifications That Matter in-Day-to-Day Work

    For this compound, model variants are linked to the needs of downstream processes. Our main production run delivers a white to light yellow crystalline solid. We consistently maintain assay values above 98 percent by HPLC, surface moisture below 0.25 percent, and a well-controlled sulfate ratio. These numbers might feel academic, but they shape the way our clients process, store, and blend. Too much residual water or trace nitrate, and batch yields in dye manufacturing drop, causing plant managers to lose sleep over waste and cost. We learned early that purity isn’t a marketing pitch — it’s a direct lever on scale-up success.

    How 2-Nitro-1,4-Benzenediamine Sulfate Finds Its Place in the Industry

    The largest demand for this compound shows up in oxidative hair coloring. It brings depth and nuance to darker shades, especially when blended with other oxidative dye precursors. From direct conversations with formulation chemists, the regulatory standards for hair dye safety have tightened worldwide. This places even more importance on tight controls over impurity profiles and trace heavy metals. For manufacturers like us, the real challenge isn’t just hitting a target purity once but doing so for every single batch, month after month, year after year. The direct connection between what leaves our filling lines and the safety of an end consumer on the other side of the globe keeps our team motivated to refine every production step.

    Why Choose the Sulfate Over Other Salts or Bases?

    Comparisons often crop up with other forms of the compound, especially the free base variant and its hydrochloride salt. Each comes with different solubilities, chemical reactivity, and shelf stability. Clients seeking finer control over the dissolution process in aqueous systems tend to pick the sulfate. The free base clumps, oxidizes faster in the presence of air, and often arrives in darker, less appealing batches. During multi-step synthesis, that extra unpredictability can throw off yields or foul the reactor. Our sulfate version, after years of process tweaks, handles better, resists caking, and stores longer under high humidity conditions. The sulfate’s lower intrinsic toxicity and reduced dusting during handling mean fewer headaches at the plant level, both for workers and for compliance officers tracking workplace exposure.

    Manufacturing Realities: Lessons from the Plant Floor

    Many outside the field never see the day-to-day complications chemical makers face. Batch-to-batch consistency isn’t an abstract goal. Humidity spikes can throw off crystal formation. Trace metal levels in input nitroaniline drive quality challenges downstream. We’ve spent years investing in better filtration and drying systems, and each upgrade followed actual plant incidents — not marketing wishes. Sulfones and other by-products slip through if you treat purification as an afterthought, but they pile up as off-odors or problematic color shifts in the client’s final product. We track every raw material lot, recalibrate analytical instruments, and keep lines transparent for client audits. Crafting sulfate batches means learning from each misstep, logging them, and planning adjustments before the next run. Big wins in chemical production rarely come from breakthroughs; they come from hundreds of little fixes stacked up until the quality curve flattens out at the top end.

    Building Safety and Compliance Into Each Batch

    Product safety doesn’t begin at the warehouse door. Our product line went through REACH registration, South Korean K-REACH, and detailed risk assessments for major regions. Customer quality teams ask us for exhaustive impurity profiling, including sulfated ash content, trace solvents, and presence of amines, because regulations in their home countries demand it. Each batch comes with a certificate of analysis signed off directly by our QA team, and we often share stability studies covering six months and one year at elevated temperatures. Our safety team fine-tunes the dust control measures, and since the sulfate form generates lower respirable particulates than other salts, operator safety metrics improve season-by-season. Top producers choose the safest, most reproducible option — not just for cost, but because non-compliant product triggers recalls and downstream lawsuits.

    Environmental Footprint and Sustainability Efforts

    Improving environmental impact forms a constant thread in our daily operations. Ammonia effluent from the old reduction step once forced us to haul waste to a third-party facility. Today, we recover more than 70 percent of it for reuse. Acid scrubbers and VOC controls reduce emissions close to mandated thresholds. Our R&D group recycles process water and minimizes residual sulfate in waste output. Feedback from eco-audits steers future investments. Customers in Europe and North America ask detailed questions about origin, energy use, and by-products. No one investing in sustainable consumer brands accepts “just enough” compliance. We’ve converted old, high-waste processes to more selective hydrogenation approaches, trading reaction speed for lower environmental load. The upshot isn’t greenwashing, but lower long-term operating costs and less regulatory exposure for buyers and their brands.

    Documentation: Why It’s More Than Paperwork

    Few things test a chemical maker’s discipline like documentation. We keep a rolling log of every in-process control check, analytical spectrum, and batch deviation. It isn’t paperwork for its own sake. During a client’s product recall, our detailed batch records let us track precisely which drum might be in question. That level of traceability calms nerves in multinational supply chains. Importers expect to inspect batch records for two or even five years. Our clients audit not just final batch results but how in-process controls limited out-of-spec profiles before the final QC stage. Running operations tightly makes audits routine, rather than stressful, and assures customers that what arrives in their warehouse is the same as what passed initial sampling.

    Tackling Supply Chain Pressures and Market Needs

    Every year introduces new supply chain pressures — feedstock swings, new safety regulations, and unpredictable shipping delays. Global trends often shift demand unexpectedly. Ingredients linked to consumer health attract attention from regulators, advocacy groups, and news headlines. We keep buffer stocks not as a marketing ploy, but as insurance against raw material shortages and transport disruptions. We lock in long-term contracts on key input chemicals to shield client supply lines from market whiplash. As global sourcing scrutiny increases, traceability, country-of-origin data, and inventories at regional hubs carry practical as well as strategic weight. We maintain open communication with end users to spot emerging trends. Whether it’s a spike in hair color trends in South America or ingredient restrictions in Asia, staying quick with production adjustments and documentation updates becomes a competitive edge, not simply a box to check.

    Technical Support Built on Real-World Experience

    Clients rarely want classroom theory; they need solutions to current plant problems. Our technical team fields calls about unexpected precipitation, tough-to-filter intermediates, or reaction tank cleanouts. We’ve seen what happens when particle size drifts off-spec, or a shipment sits at an unventilated port for too long, leading to caking or color change. Many insights about mixing order, pH adjustment, or order-of-addition protocols come from troubleshooting in partnership with process engineers and plant managers. We pass on better storage guidelines and optimized addition routines based on these real issues, not just literature values. Better outcomes and higher yields often follow not from over-engineering but from listening to people directly handling the product during night shifts and tight turnarounds.

    Challenges Facing Manufacturers and Users

    Chemical production never delivers perfect predictability. There’s always a risk of out-of-spec product, whether from a raw material hiccup or a processing issue. Sometimes, shifts in color or particle distribution only show up at scale, not in small lab batches. Users sometimes underestimate how small changes in raw material properties trickle down the line. We encourage open communication if anything seems off, no matter how small. Delays in reporting lead to waste, while swift feedback loops catch issues before they cause real cost and schedule overruns. Regulations change fast, too. What met compliance one year may fail the next. That reality demands vigilance both in the plant and after material leaves our doors.

    Innovation Driven by Customer Demands

    Many of our process improvements trace straight back to end-user feedback. A client flagged tough filtering behavior when switching to closed-system processing, showing us where our particle size distributions needed tightening. Another customer dealing with shifts in regulatory limits on amines prompted an overhaul of purification steps. By re-examining which process by-products might show up in sensitive downstream uses, we found ways to cut trace levels, improving both safety and reputation. Collaboration isn’t always straightforward, but time spent with users in their own plants often yields better results than top-down mandates from process labs.

    Comparing 2-Nitro-1,4-Benzenediamine Sulfate with Related Products

    Multiple oxidative dye intermediates sit in similar chemical families. Clients sometimes debate switching products to chase modest price breaks or newer ingredient profiles. Years in the field show that switching between different salts — or to the free base — brings unanticipated side effects. The sulfate form usually outperforms due to lower dusting and greater solubility in formulation. Adopting another variant often lands users with stickier processing, greater safety risk, or variability batch-to-batch. Actual data from continuous operations confirms that minimizing raw material changes means fewer process upsets, easier regulatory compliance, and smoother scale-ups. The sulfate’s consistency keeps production lines running with less supervision and lower waste rates, ultimately cutting costs across the value chain.

    Partnering Across the Value Chain

    End-to-end quality doesn’t begin or end with the manufacturer. We stay in regular communication with both upstream raw material suppliers and downstream users. Open, direct feedback on transportation and warehousing conditions, as well as labeling or handling preferences, proves essential in avoiding supply chain surprises. Pre-shipment samples and long-term product stability tracking build shared confidence. Third-party audits and shared best-practices sessions highlight improvements. We value close working relationships with our distributors and large-volume clients, who often uncover better storage and dispensing solutions while managing bulk volumes or moving chemicals into tightly regulated settings.

    Global Regulatory Trends Ripple Through Every Batch

    Legislation affecting chemicals evolves at breakneck speed. Shifts in permitted impurities, labelling, and allowable exposure drive continuous change in how intermediates must be produced, packaged, and shipped. Our compliance staff tracks updates across the US, EU, South America, and Asia. Implementing upgrades is never trivial — sometimes a single new trace contaminant limit calls for re-tooling of both plant hardware and analytical testing. We invest in up-to-date analytical instruments and cross-train operators to spot problems early. Strategic planning and flexibility shield both us and our clients from regulatory surprises. Years of firsthand experience have proved that staying out ahead of change reduces risk for everyone involved, from production staff to end consumers.

    Supporting Customers in a Fast-Moving Landscape

    The daily job of a chemical manufacturer doesn’t finish with the last ton shipped. Our technical support team fields questions about process adaptation, quality troubleshooting, environmental reporting, and safe handling. We share both best-practice recommendations and field reports from other clients, passing along lessons learned to improve operations for others. Transparency underpins every shipment, every COA, and every handling guideline we provide. We answer as many tough questions as customers care to throw our way, because their regulatory teams, QC analysts, and process chemists depend on it. Open lines and direct access to in-house experts help customers feel confident in both the product and our long-term partnership.

    Looking Forward: Building Reliability into Every Gram

    Reliability forms the foundation of trust between a chemical manufacturer and clients. We’ve learned, project by project, that consistency across batches, timely communication, and thorough documentation matter more than glossy brochures or clever advertising. The real differentiator in the field is how well a product like 2-Nitro-1,4-Benzenediamine Sulfate works in actual operations — under the stress of high-volume, real-time manufacturing, shifting production schedules, and regulatory scrutiny. The more transparent we are with results and challenges, the stronger our client partnerships grow. We adapt production, logistics, and safety protocols with every uptick in demand or regulatory change, aiming to support both established industries and new markets as they evolve.

    Conclusion: The Manufacturer’s Commitment Behind Every Shipment

    Years of production, troubleshooting, and learning have taught us that real value comes from a keen focus on process, safety, and end-user needs. Every drum or bag of 2-Nitro-1,4-Benzenediamine Sulfate that leaves our facility represents more than a spec sheet. Behind it lies a culture of attention to technical question, discipline in quality control, and the steady grind of improvement, fueled by direct conversations and feedback from those who transform our product into finished goods. Our team stands ready for new challenges and eager to work alongside customers as new requirements, both technical and regulatory, emerge across the industry.