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2-Naphthylamine-6-Sulfonmethylamide

    • Product Name 2-Naphthylamine-6-Sulfonmethylamide
    • Alias 6-(Aminosulfonyl)-2-naphthylamine
    • Einecs 621-375-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    306362

    Chemical Name 2-Naphthylamine-6-Sulfonmethylamide
    Molecular Formula C11H10N2O2S
    Molecular Weight 234.28 g/mol
    Cas Number 615-33-2
    Appearance Light yellow to beige solid
    Solubility In Water Slightly soluble
    Boiling Point Decomposes before boiling
    Synonyms 6-(Aminosulfonyl)-2-naphthylamine
    Pubchem Cid 22009
    Unii A9GJE1XG60
    Storage Temperature Store at room temperature

    As an accredited 2-Naphthylamine-6-Sulfonmethylamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100g amber glass bottle with a secure screw cap, labeled "2-Naphthylamine-6-Sulfonmethylamide," includes hazard symbols and handling instructions.
    Shipping 2-Naphthylamine-6-Sulfonmethylamide should be shipped in compliance with relevant chemical regulations. Use tightly sealed, chemically resistant containers, and cushion with suitable packing material. Label as a potentially hazardous chemical. Protect from moisture, heat, and direct sunlight. Ensure transport documentation includes safety and handling instructions per SDS guidelines and local regulations.
    Storage 2-Naphthylamine-6-Sulfonmethylamide should be stored in a tightly sealed container, away from light, moisture, and incompatible substances such as strong oxidizers. Store at room temperature in a cool, dry, well-ventilated area, preferably in a chemical storage cabinet. Ensure proper labeling and secure storage to prevent unauthorized access. Use personal protective equipment when handling the chemical to avoid exposure.
    Application of 2-Naphthylamine-6-Sulfonmethylamide

    Applications of 2-Naphthylamine-6-Sulfonmethylamide in Industrial Manufacturing

    As a direct production manufacturer of 2-Naphthylamine-6-Sulfonmethylamide, we support a defined range of real downstream industrial sectors where this compound functions as a critical intermediate or additive. Below, we outline its established, high-impact applications, with scenario-specific details structured for technical and procurement stakeholders.

    1. Disperse Dye Intermediate for Synthetic Fiber Textiles

    Our compound serves as a sulfonamide-based intermediate in the synthesis of selected disperse dyes used for polyester and acetate textile coloration. Dyestuff makers employ it in diazotization and coupling processes, capitalizing on its unique amide-sulfonyl structure to impart desirable chromophore stability and washfastness required by mass-market apparel producers.

    Industry compliance standards

    • OEKO-TEX® Standard 100 Annex 6
    • ZDHC MRSL v3.1
    • REACH Regulation EC No.1907/2006 (Dyestuff Ingredient Listing)
    • ISO 105-C06: Textile — Tests for colour fastness

    Typical usage ratio

    • 5–18% of the total weight of coupled intermediates in specific monoazo dye synthesis; final proportion set according to required shade depth and fastness, and monitored via chromatography and spectrophotometry.

    Downstream process integration

    • Introduced during aqueous diazotization, followed by in-situ sulfonamide coupling; compound addition occurs once pH adjustment stabilizes process temperature (0–5°C), prior to the final neutralization and spray-drying.

    Final product types

    • Disperse dyes for high-speed jet dyeing of polyester filament and microfiber textiles
    • Dye concentrates for thermosol and pad-dry-cure operations in apparel finishing
    • Ready-to-use dye dispersions for automotive polyester upholstery

    2. Rubber Chemical Intermediate for Antioxidant Manufacturing

    This chemical acts as a key intermediate in producing certain aromatic amine antioxidants, notably for applications in heat- and fatigue-resistant natural and synthetic rubber compounds. Its incorporation delivers stability against oxidation and UV exposure, a priority for tire and industrial belt manufacturers.

    Industry compliance standards

    • ASTM D4676: Classification System for Rubber Chemicals
    • ISO 9001:2015 QMS adherence for supplier traceability
    • EU Regulation (EC) No 1907/2006 – REACH (Annex XVII for restricted substances)
    • GADSL for automotive rubber goods

    Typical usage ratio

    • 2–12% relative to total weight of all aromatic amines in blending batches; percentage adapted according to rubber type (NR, SBR, EPDM) and required atmospheric aging test outcomes.

    Downstream process integration

    • Fed into amine alkylation reactors during the multi-step synthesis of rubber antioxidants; integration occurs after pre-reaction purification and prior to antioxidant isolation by vacuum distillation or spray drying.

    Final product types

    • Amine-based antioxidants for all-season and performance automotive tires
    • Chemical stabilizers for conveyor and V-belts subject to cyclical thermal stress
    • Protective agents for high-durability rubber linings in mining and oilfield pipelines

    3. Pharmaceutical Dye Intermediate for Diagnostic Reagents

    Selected pharmaceutical-grade manufacturers use this compound to produce azo-based diagnostic stains utilized in clinical laboratory tests—including cytochemical and histological analysis—where batch-to-batch reproducibility and biocompatibility are essential. This scenario requires the highest scrutiny for contaminant control and compound provenance.

    Industry compliance standards

    • USP-NF (United States Pharmacopeia–National Formulary) for lab chemical reagents
    • ICH Q3A/B: Impurity Limits
    • GMP Annex 1 for Active Pharmaceutical Ingredients
    • Directive 98/79/EC on in vitro diagnostic medical devices (IVDs)

    Typical usage ratio

    • 3–9% of the total mass of dye precursor blends; precise level governed by target stain intensity and cytotoxicity validation data.

    Downstream process integration

    • Added during the coupling phase of azo dye synthesis, upstream of final purification (recrystallization/filtration); compound dosing controlled under GMP protocols and traceable documentation.

    Final product types

    • Azo dye stains for blood and tissue specimen microscopy
    • Histological diagnostic kits for hospital and research laboratory use
    • Quality-controlled staining solutions for automated clinical diagnostic platforms

    4. Pigment Intermediate for Colorant Synthesis in Coatings

    Paint and industrial coatings formulators value this raw material for its role in synthesizing specific high-durability azo pigments, used where lightfastness and water resistance are critical. Its functional properties promote pigment consistency vital in demanding architectural and industrial coatings.

    Industry compliance standards

    • ISO 787-24: General Methods of Test for Pigments and Extenders
    • EN 71-3: Safety of Toys—Migration of certain elements (for coatings on toys)
    • ASTM D01.42: Committee for Architectural Coatings
    • EU Ecolabel criteria for indoor paints and varnishes

    Typical usage ratio

    • 6–16% of total aromatic amine intermediates per pigment synthesis batch; final percentage based on color index requirements (e.g., CI Pigment Yellow 183) and resistance tests stipulated by customer QC specifications.

    Downstream process integration

    • Incoporated during initial condensation and coupling stages, before purification and pigment flushing; dosage monitored through in-process HPLC analysis to ensure color uniformity and low residue content.

    Final product types

    • High-performance pigments for exterior and marine paints
    • Color concentrates for plastics and powder coatings
    • Pigment dispersions for water-based and UV-cured printing inks

    5. Chemical Intermediate for Specialty Inks Production

    The formulation of specialist printing inks, such as those for security documents and anti-counterfeiting, relies on this compound as a molecular building block for certain colorants that offer both chromatic uniqueness and solvent fastness. Ink manufacturers demand high purity and consistency in the raw feed to meet the traceability and regulatory documentation required by sensitive industrial sectors.

    Industry compliance standards

    • ISO 2846-1: Color and Transparency Measurements of Printing Ink Sets
    • GMP for Printing Inks Used on the Non-Food Contact Surfaces of Food Packaging (EuPIA)
    • RoHS Directive (2011/65/EU) for electrical device coatings
    • ISO 14298: Management of Security Printing Processes

    Typical usage ratio

    • 7–15% of aromatic amine intermediates per ink colorant synthesis; adjusted per desired optical density, printfastness, and client application method (gravure, flexographic, digital, or offset).

    Downstream process integration

    • Dosed during pre-polymerization or azo coupling stages, prior to filtration and solvent exchange; rigorous batch identity control is maintained to document chain of custody and composition for downstream users.

    Final product types

    • High-durability inks for anti-tamper security features
    • Printing inks for passports, certificates, and brand protection labels
    • Non-conductive printing inks for smartcard circuitry coatings
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    Certification & Compliance
    More Introduction

    2-Naphthylamine-6-Sulfonmethylamide: An Experienced Manufacturer's Perspective

    Overview of 2-Naphthylamine-6-Sulfonmethylamide

    Our experience with 2-Naphthylamine-6-Sulfonmethylamide stretches back through many years and thousands of metric tons. This is a specialty intermediate that often draws attention from dye and pigment manufacturers, as well as certain pharmaceutical and agricultural players who recognize its unique chemical structure. Our model focuses on 99.5% purity verified by HPLC, and we produce it using tried-and-true sulfonation, amidation, and purification steps, with each batch passing through both in-house and independent QC labs.

    Consistent Quality Backed by Deep Experience

    Process control stands as the linchpin of our manufacturing operation for 2-Naphthylamine-6-Sulfonmethylamide. Sulfonation of the 2-naphthylamine core can be capricious, showing sharp sensitivity to temperature, pH, and solvents. We’ve invested in modern reactors and DCS automation. Operators watch process variables closely, informed by years of hands-on troubleshooting. Minor heat excursions or solvent-side impurities can introduce tints or byproducts, a lesson one only understands after making enough product to witness these subtle shifts. We have tailored raw material intake and pre-treatment steps to the specific traits of each feedstock lot: not all 2-naphthylamine behaves the same, especially if sourced from different global vendors, so we validate each lot for residual amines, ash content, and trace color bodies before it even reaches our main reactor.

    Batch records show most exclusions result either from trace organic colorants or excess moisture. Our drying protocol, which combines vacuum and staged heating, keeps residual water below 0.08%, directly impacting product shelf life and filterability. Several downstream customers once reported clogs during filtration, traced back to excess water or particles below 2 microns. Our response merged sieve improvements with fine-tuned crystallization rates, an approach informed by numerous feedback cycles and collaborative trials with our partners—a relationship based on trust and iterative improvement, not short-term sales.

    Specifications That Matter to End Users

    In the practical world—not just on whiteboards—what matters to you often hinges on three points: consistency in purity, reliable logistics, and transparent communication about changes or concerns. We ship the 2-Naphthylamine-6-Sulfonmethylamide in 25 kg fiber drums, each batch supported by a COA signed off by senior QA staff. Purity by HPLC ranges 99.5% to 99.7% batch by batch, with byproduct levels (like free sulfonic acids or methylamines) under 0.2%. pH in 1% aqueous solution typically falls between 6.8 and 7.3. These testing criteria came from real conversations with dye formulators who saw unwanted reactivity or color drift when earlier, less-controlled products entered their systems. Low ash and negligible inorganic contaminants allow for direct dispensing without ongoing filtration for most industrial scale operations.

    The physical form matters. Our manufacturing output can be tuned from dense powder to a slightly granulated state depending on your application needs. Some downstream formulators prefer granular for dust suppression, while others lean toward fine powder for fast dissolution. We know that even a minor change at the manufacturing step—dryer finish, cooling stage, or packaging transfer—will reach your operators in handling, so each run gets a dry flow rate test plus laser diffraction studies for particle size, so nothing surprises you when the drums open.

    End Uses: What Grows From Reliable Intermediates

    2-Naphthylamine-6-Sulfonmethylamide found its niche thanks to a unique reaction profile. In azo dye chemistry, it provides clean, deep color bases, especially in acid dyes and direct dyes for textile and paper applications. The sulfonmethylamide group delivers increased water solubility and resistance to fading—two factors that textile manufacturers value when dealing with tough industrial laundering protocols. Some of our long-term customers also chase substitution reactions based on this group, especially in pharmaceutical synthesis, where the electron-donating effect on the aromatic ring allows for selective transformations in more elaborate downstream products.

    We worked hand in hand with a specialty pigment house that needed sharper color points on their blues and violets. Through six months of iterative changes on both sides—tuning both our intermediary’s purity and their dye couplings—the result hit the right CIE L*a*b* readings without extra processing steps or heavy metals. That’s only possible through direct dialogue and a willingness to customize everything from drying time to packaging liner thickness, not just churning out a commodity. This type of partnership reflects what most real-world chemical manufacturing looks like when everyone shares realistic goals and technical expertise.

    In the agrochemical sector, the material’s function as a coupling agent shows up in certain sulfonamide herbicide syntheses. Here, trace amine impurities can poison downstream catalysts or alter the selectivity of coupling steps, so our focus on trace organics and infra-red characterization pays off in batch runs that don’t collapse midway. These are details missed in procurement exercises focused solely on headline purity. We’ve kept multiple customers returning year after year because our process eliminates repeat surprises—an achievement only possible by taking every batch seriously, regardless of order size.

    Comparative Insights: Not All Intermediates Are Alike

    People often think, unless prompted otherwise, that two intermediates with similar names or formulas serve equally well. It doesn’t take long in a production lab to learn how slight tweaks—not just in the molecular backbone but in side group choice, isomer ratios, or trace contaminants—shift everything downstream. Take 2-Naphthylamine-sulfonic acids, for example. While some downstream applications accept these as drop-ins, we’ve seen their color, binding performance, and storage behavior differ starkly, especially when subtle side-reactions with trace metals or low-level oxidants occur.

    Our 2-Naphthylamine-6-Sulfonmethylamide stands apart from simple sulfonated 2-naphthylamines or generic naphthylamine sulfonic acid salts. The methylamide group blocks undesired side reactions with certain couplers, so you get fewer byproducts and higher yields. This functional group also alters water solubility and chemical reactivity, meaning process windows during dye manufacture shift—faster dissolution, reduced need for organic solvents, and more predictable pH stability. Customers who previously relied on straight sulfonated naphthylamines often report increased handleability and less color drift after switching to our material.

    Recent feedback from a detergent dye formulator pointed to lower residue buildup after switching to our sulfonmethylamide, compared to an Eastern European supplier’s basic sulfonic acid. Not all of that traces to chemistry; it also reflects improved filtration at our site and real communication about “off spec” shipments—not just red-tagging, but documenting the root cause, sharing batch investigations, and, if needed, rerunning campaigns to meet specs. Owning the full chemical process chain, rather than relying on third-party blending or outsourcing, allows us to make, test, and adjust formulations in real time.

    Transparency and Traceability: Our Long-Term Approach

    With regulatory authorities tightening on aromatic amines and their derivatives due to possible toxicity, our philosophy emphasizes end-to-end traceability. Each drum carries a lot number that links back to operator logs, remediation steps, and analytical results, including HPLC chromatograms and FTIR spectral libraries. Recently, a European dye house needed additional documentation to demonstrate compliance with REACH and local ecolabel programs. Because we own our synthesis and QA process, we supplied complete dossiers rapidly—something only practiced, committed manufacturers can consistently deliver.

    Our process logbooks include more than numbers. Operators jot down observations on viscosity, equipment noise, or unusual odors—a practice nurtured through years of continuous improvement culture borrowed from both local and international best practices. We attribute our two consecutive industry quality medals not just to analytical numbers, but to the hard-earned knowledge spread among our shift supervisors, maintenance staff, and QA chemists. Whenever process interruptions surface, such as a steam valve failing or a raw material drum showing unexpected tint, these handwritten details speed root cause analysis and return to spec faster.

    Safe Handling and Environmental Care

    Years of experience have shown how important safe handling practices are with any aromatic amine and sulfonamide. We maintain closed-system transfers between reactors, centrifuges, and drying equipment. Dust suppression—often overlooked in lower-cost plants—receives special attention in both formulation and packaging stages. Our final product packaging uses triple-layer liners, reducing dust escape, and we train our warehouse staff to check for liner damage before drums leave our site.

    Waste streams from the sulfonation and amidation steps carry potential environmental burdens. Over the years, we’ve added both bioreactor treatment and acid-base neutralization loops to keep effluent well ahead of regulatory curves. Third-party audits from international chemical buyers have confirmed our effluent numbers, and several shared audit results with their downstream customers. That’s something our team feels proud of; environmental compliance isn’t just for checklists, it means staying respected and welcome in the global market.

    Working With Us Versus Generic Producers

    The world does not lack for “white label” intermediates or generic material blended by traders who never set foot in a synthesis lab. Our edge stems from owning, refining, and improving each step, every year. Consistency across lots is something we take personal pride in, not just because it improves our bottom line—return and premium customers are built on reliability—but because all of us want to work in a plant where our product is trusted and stories of failures are the rare exception, not the norm.

    We invite regular technical audits by both customers and independent experts, so the conversation doesn’t stall at a single COA. Visiting project partners walk our production line, see our QC screens, and discuss technical questions on micron-level residue, batch release criteria, or future regulatory risk. That open-door approach tends to erase doubts and foster frank dialogue about production challenges, scale-up, or process changes, which traders or repackers simply cannot match.

    If a customer needs a variant with a custom particle size, altered drying conditions, or specific residual solvent controls, our team engages directly: modifying process parameters, tracking resulting property changes, and ensuring regulatory filings reflect the changes. Past collaboration with a major pigment house led to a new grade with 30% higher flowability, cutting their handling losses without affecting reactivity. Another case with a pharmaceutical manufacturer saw us introduce a water wash at a critical step, halving their color body levels in one go. Each adjustment anchors itself in operator feedback and real-world trials.

    Working Together to Drive Chemical Innovation

    Some of the biggest process gains in 2-Naphthylamine-6-Sulfonmethylamide came from customer-driven innovation. We encourage joint pilot runs, offer onsite support for sampling, and report full analytical results beside every shipment—sometimes at a level of detail that surprises even established buyers. Direct feedback from users often triggers internal review sessions in our process lab, whether it’s a slight uptick in byproduct count or a subtle shift in odor over time. That feedback not only covers our intermediate; it also leads to advice on tank cleaning, process optimization, and storage practices, which extend product shelf life and keep everyone happy.

    We openly acknowledge the global turbulence occasionally seen in aromatic amine supply chains—from new regulations to shipping disruptions or changing raw feedstock prices. Navigating these swings means more than cost discussions. We maintain a modest strategic reserve, so long-term buyers rarely face surprise gaps. Open, pragmatic communication about constraints, planned maintenance, or global trend shifts fosters resilience on both ends of the transaction.

    Looking Ahead: Where Practice and Progress Meet

    2-Naphthylamine-6-Sulfonmethylamide is not a product for beginners or opportunistic traders. Making, tracking, and improving each lot takes a factory unafraid to invest in people, equipment, and transparently documented processes. Each operator knows the chain doesn’t end at our loading dock; it extends through your tanks, reactors, and finished goods out into the marketplace. Every improvement in purity, flowability, or contaminant control saves headaches later—whether that’s in batch failures, regulatory checks, or simple day-to-day production reliability.

    We will keep listening and learning in partnership with users—longstanding or new—who demand not only the best technical outcome, but also a relationship based on honesty, hard-won experience, and an unrelenting drive for improvement. That’s what it takes to succeed in the real chemical manufacturing world, and that’s what keeps us motivated to come back every day and make your next batch just that little bit better.