Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-N-Butylpropane-1,3-Diol

    • Product Name 2-N-Butylpropane-1,3-Diol
    • Alias 1,3-Butanediol, 2-butyl-
    • Einecs 202-313-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    998019

    Cas Number 18979-61-8
    Molecular Formula C7H16O2
    Molecular Weight 132.20 g/mol
    Iupac Name 2-n-butylpropane-1,3-diol
    Synonyms 2-n-Butyl-1,3-propanediol
    Appearance Colorless to pale yellow liquid
    Boiling Point 246-248 °C
    Density 0.950 g/cm3 (approximate)
    Melting Point -60 °C (approximate)
    Solubility In Water Moderately soluble
    Flash Point 120 °C (closed cup)
    Purity Typically ≥98%

    As an accredited 2-N-Butylpropane-1,3-Diol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-N-Butylpropane-1,3-Diol is packaged in a 250g amber glass bottle with a secure, tamper-evident screw cap.
    Shipping 2-N-Butylpropane-1,3-diol should be shipped in tightly sealed containers, protected from moisture and direct sunlight. Transport in accordance with applicable chemical regulations, ensuring proper labeling and documentation. Handle with care to avoid leaks or spills, and store in a cool, dry, and well-ventilated area upon receipt.
    Storage 2-N-Butylpropane-1,3-diol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, protected from direct sunlight and moisture. Keep away from sources of ignition, strong oxidizing agents, and incompatible substances. Ensure proper labeling, avoid extreme temperatures, and use secondary containment to prevent leaks or spills. Store in accordance with local regulations and safety guidelines.
    Application of 2-N-Butylpropane-1,3-Diol

    Applications of 2-N-Butylpropane-1,3-Diol in Industrial Manufacturing

    2-N-Butylpropane-1,3-diol serves as a multi-functional intermediate and performance additive, supporting precise industrial applications in fine chemicals, cosmetics, specialty coatings, high-end lubricants, and pharmaceutical synthesis. Its well-characterized properties provide critical functional benefits where reliability, purity, and regulatory acceptance are essential. Below, we detail key downstream sectors utilizing this raw material, with direct reference to industry compliance standards and real processing routes.

    1. Cosmetic Formulations for Skin Care Bases

    Cosmetic manufacturers incorporate 2-N-Butylpropane-1,3-diol as a premium humectant and co-solvent in advanced skincare formulations, significantly enhancing moisture retention, dermal absorption, and stability of active ingredients. Its low irritation profile suits hypoallergenic emulsions, serums, and lotions. Production chemists select this diol to optimize texture, extend shelf life, and support a balanced solvent system within pH-sensitive matrices. Established quality control routines govern blending and in-process checks to maintain lot consistency. Formulators may vary diol concentration based on emulsion type, targeted hydration, and product claims.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on cosmetic products
    • US FDA 21 CFR Part 700 Subchapter G
    • China Cosmetic Safety and Technical Standards 2015
    • ISO 22716:2007 Cosmetics GMP

    Typical usage ratio

    • 2% – 8% w/w, adjusted based on product type (e.g., higher for serums, moderate for creams)

    Downstream process integration

    • Added during the aqueous phase of cream or gel compounding under agitation, prior to emulsification and final homogenization

    Final product types

    • Moisturizing face creams
    • Hydrating serums
    • Body lotions for sensitive skin
    • After-sun gels

    2. Pharmaceutical Intermediate in API Synthesis

    Active pharmaceutical ingredient (API) producers use 2-N-Butylpropane-1,3-diol as a core building block in multi-step synthesis of selective beta-blockers and lipid-lowering compounds. Process chemists value its predictable reactivity in esterification and alkylation, facilitating controlled modification of molecular scaffolds. This diol supports robust validation and traceability under GMP conditions, addressing drug master file (DMF) transparency requirements. Analytical labs monitor diol introduction at the specific synthetic stage to maintain regulatory documentation for critical intermediates.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • US FDA Good Manufacturing Practice regulations (21 CFR Parts 210, 211)
    • EU GMP Volume 4 Part II
    • Ph. Eur. & USP monographs (as intermediary reference)

    Typical usage ratio

    • Stoichiometric input based on reaction step, generally 1.1 – 1.3 equivalents per mol of final product during critical coupling stage

    Downstream process integration

    • Charged as a key intermediate at controlled temperature in synthesis reactors during formation of target molecule backbone

    Final product types

    • Selective beta-blockers (API grade)
    • Lipid-lowering drug molecules (API grade)
    • Hydrophilic pharmaceutical intermediates
    • API precursor compounds (filed under DMF systems)

    3. High-Temperature Synthetic Lubricant Additive Manufacturing

    Specialty lubricant and grease producers select 2-N-Butylpropane-1,3-diol for its thermal stability and controlled polarity, enhancing ester base oil performance in formulations for demanding mechanical and electronic environments. Compounders optimize its addition to improve lubricity, oxidation resistance, and deposit control. The diol's molecular structure allows predictable interaction with polyol esters and synthetic hydrocarbon stocks, supporting precise viscosity grade adjustment and friction modification. Regulatory frameworks dictate levels for indirect contact or incidental food processing lubrication.

    Industry compliance standards

    • NSF International ISO 21469 for lubricants with incidental food contact
    • DIN 51517 (lubricating oils for industrial machinery)
    • REACH Regulation (EC) No 1907/2006 (substance registration and safety)
    • OECD Good Laboratory Practice (GLP) for product qualification

    Typical usage ratio

    • 0.5% – 4% w/w in synthetic ester-based lubricants, depending on operating temperature and required anti-wear profile

    Downstream process integration

    • Introduced in blending vessels post base oil pre-mix, prior to final additive combination and vacuum dehydration

    Final product types

    • High-temperature synthetic compressor oils
    • Food-grade lubricants for processing equipment
    • Electronic cooling fluids
    • Precision mechanical greases

    4. Reactive Diluent in Specialty Polyurethane Systems

    Manufacturers of specialty coatings and adhesives employ 2-N-Butylpropane-1,3-diol as a chemically reactive diluent in high-solids, solvent-free polyurethane formulations. Its diol groups participate directly in network formation with polyisocyanates, yielding flexible, low-viscosity prepolymers with reduced volatile organic compound (VOC) output. Coating engineers determine dosing relative to required film flexibility, cure speed, and final mechanical properties. Consistent QC sampling ensures residue control and proper integration into prepolymer chains for industrial-grade PU systems.

    Industry compliance standards

    • EU Regulation 2004/42/EC on VOC limits for architectural coatings
    • ISO 9001:2015 certified manufacturing system
    • ASTM D16 (Standard Terminology for Paint, Related Coatings, Materials, and Applications)
    • US EPA 40 CFR Part 59 Subpart D (VOC emissions)

    Typical usage ratio

    • 5% – 15% w/w of total polyol content, adjusted for end-use film flexibility and cure response

    Downstream process integration

    • Metered into the polyol component under inert gas at controlled temperatures, then combined continuously with isocyanate feed during prepolymer formation

    Final product types

    • High-solids industrial floor coatings
    • Solvent-free PU sealants
    • Flexible adhesives for construction panels
    • Specialty waterproofing membranes
    Free Quote

    Competitive 2-N-Butylpropane-1,3-Diol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-N-Butylpropane-1,3-Diol: Manufacturer’s Perspective on Performance and Reliability

    Producing 2-N-Butylpropane-1,3-Diol in our facility takes time, skill, and oversight. Every batch runs through a series of monitored steps, each checkpoint shaped by hands-on experience—not just compliance. Everyone involved in refinement or quality control knows this chemical by more than its CAS number; we understand what our customers expect and where this compound must fit in actual manufacturing environments. Over time, we have learned that good results come from not cutting corners. Our lines run to spec, and our records back this up, not for marketing gloss but because real production headaches leave no room for error.

    Model and Specifications: Built for High Standards

    Our primary offering of 2-N-Butylpropane-1,3-Diol, produced under closely controlled conditions, features purity levels exceeding 99%. The clear liquid form results from careful distillation, and we continually monitor for color, odor, and water content. Every shipment gets documented for batch traceability and purity. During our regular reviews, we see few requests for alternative cuts, but if you have specialized criteria, our lab team works directly with production to address these—the direct approach saves time and makes troubleshooting easier.

    We ship this compound in lined steel drums and HDPE cans, depending on order scale. Large-volume partners often pull from certified bulk containers, and our logistics team pays special attention to chain-of-custody documentation. Many procurement specialists from pharmaceutical and industrial firms reach out not simply because they read about us online, but because they know our handling and production standards reflect the expectations at their plant.

    Production Reliability: It Starts with Real Raw Materials

    We evaluate raw input stock and assess every new supplier for consistency, actual availability, and shipping history before integration. There is no point in optimizing downstream if your supply chain introduces trouble at the top. Chemical specifications and paperwork come standard, but we also check for visual appearance, contamination, and physical properties ourselves. Our resin handling and tank cleaning procedures borrow from food-grade lines—if contamination slips in upstream, every subsequent process step runs at risk. Many customers have discovered this the hard way elsewhere, and the headaches that follow a contaminated batch ripple through an entire production schedule. We avoid these pitfalls by sticking to proven protocols and verifying them with every order.

    Application Experience: What Users Actually Want

    In surfactant synthesis and advanced coatings, formulators look for a diol that will not introduce odor taint, produce unexpected chroma, or break down under heat and pH extremes. Our 2-N-Butylpropane-1,3-Diol consistently meets these markers—application labs from Asia to Europe send finished product reports back affirming its stability and cleanliness. Feedback loops between application chemists and our manufacturing group highlight issues early. Those requests inform ongoing tweaks, like tighter distillation cut settings or focused drying protocols to get water content below 0.05%. This attention gives customers more of what they care about: predictable results without repeated troubleshooting.

    Some customers run pilot lines seeking to replace solvents like ethylene glycol or propylene glycol, drawn by improved toxicological data and regulatory acceptance. We help fine-tune usage levels so new formulations don’t just scan well on a spec sheet but also deliver in real use cases. There’s no universal “better” here—a diol’s advantages depend on your exact matrix and stability profile—but our track record shows six years of successful transitions, especially in high-performance polymers and personal care bases.

    Comparisons with Other Diols: More Than Numbers

    Blending or swapping diols in a formulation often throws up both challenges and opportunities. For years, propylene glycol or butylene glycol set the bar for safety, ease of use, and broad approval. As regulations and customer preferences shift, formulators want options with lower irritancy, clear toxicological data, and physical profiles that enable broader application.

    2-N-Butylpropane-1,3-Diol carries a longer alkyl chain, giving products based on it softer sensory properties and a lower tendency to absorb water from the air. In contrast to shorter-chain analogues, this can help reduce issues with instability or clumping in systems prone to hygroscopicity. The higher boiling point improves thermal resilience, especially during high-shear mixing or in reaction vessels that run at elevated cycles. In some cases, formulators report better color stability in UV-exposed products.

    Newer specialty diols can sometimes match or exceed certain technical performance parameters, but these almost always come at higher cost or with data gaps on long-term end-user exposure. Where projects demand an ingredient already supported by several years of import registration, certified REACH status, and thorough toxicology, 2-N-Butylpropane-1,3-Diol provides a less risky, more transparent choice. This matters most to multinational clients rolling out across multiple jurisdictions, since compliance headaches grow exponentially as ingredient novelty increases.

    Handling and Integration: Practical Feedback from Real Production

    We hear from line staff about what’s easy to pump, blend, or store. 2-N-Butylpropane-1,3-Diol maintains pumpability at a broad temperature range, avoids the thickening or crystallization issues common to some other specialty diols, and washes down lines cleanly with standard solvents. Storage tanks benefit from double-sealed fittings and moisture-exclusion steps; our in-house best practices guide reflects real-world experience, not just chemical theory.

    Customers frequently share batch reports and, at times, troubleshooting queries—it’s not always about the chemical itself, but how a given process step reacts to subtle changes. Sometimes, as temperatures swing or new surfactants get trialed, small shifts in residual water or trace impurity can affect yield. Our technical staff reviews data from these runs, looks for trends, and works to anticipate process tweaks so issues do not spiral into recalls or large-scale scrapping of finished material. The open-door relationship we maintain with customers—often spanning many years—lets us flag and fix problems at an early stage. This working style pays better dividends than simply shipping drums and closing files.

    Sustainability: Doing More with Less

    Every chemical facility faces pressure to simplify waste streams and cut carbon footprint without sacrificing output or product safety. We have invested in closed-loop solvent recovery and vapor capture systems on relevant lines. By recovering overheads from initial distillation passes, we reduce both environmental impact and cost. Our wastewater plants monitor for byproducts from oxidation and incompletely reacted precursors, logging every load. Rather than treat environmental impact as an abstract metric for annual reporting, we tie improvements directly to operational savings and real reductions in permit fees. Environmental engineers in our plant are given access to performance metrics and can make actual line change recommendations, not just fill out compliance paperwork.

    Projects to reformulate away from persistent, bioaccumulative solvents have increasingly involved 2-N-Butylpropane-1,3-Diol as a less problematic core ingredient. Its low volatility and favorable breakdown profile simplify regulatory filings, particularly in the EU and North America. In many customer pilots, replacing certain older glycols provides both a handling and environmental benefit, reducing paperwork associated with hazardous substance management—a pragmatic win, not just a headline.

    Worker Safety and Regulatory Know-How

    GMP production scripts and regular worker training track back to our experience with older, less forgiving glycols, where exposure meant recurring skin problems and complex ventilation requirements. Compared to some harsher analogues, 2-N-Butylpropane-1,3-Diol demands less PPE at the drum-filling and QC sampling stations, with fewer irritancy incidents logged over hundreds of man-hours. Regulatory compliance doesn’t just sit in a filing cabinet—we consult with in-house staff about glove performance, safe storage, and spill cleanup using proven neutralizing agents. This day-in-day-out experience means our teams can address audits with practical insight and help downstream users embed safer handling protocols in their own shops.

    Product Life Cycle and Shelf Behavior

    Many customers worry about degradation, water uptake, or shelf drop-off. Our warehouse data matches what users report: 2-N-Butylpropane-1,3-Diol keeps stable for over a year in unopened drums, provided key storage rules are followed. After dozens of stability tests on retained samples, contents stay within spec for acid value, color, and purity up to 24 months—actual duration depends on drum temperature and humidity control. Real losses of batch quality almost always trace back to compromised seals or poor handling on arrival, not inherent chemical instability. To minimize risks, our logistics group documents every handoff, tracks ambient warehouse conditions, and stresses the value of quick transfer to on-site tanks after receipt.

    For customers in formulation development, handling practices can shift based on local conditions. In dry, cool climates, material stays trouble-free under standard warehouse protocols. Tropical or unconditioned storage demands more vigilance on seal integrity and temperature monitoring. We update our guidance to reflect changing climate realities—experience shows that plant efficiency goes up when all parties know and act on practical storage rules, not just manufacturer legends.

    Continuous Improvement: What Yearly Upgrades Deliver

    Every twelve months, production teams review both internal data and feedback from global partners. The focus lies on reducing impurity levels, improving consistency of supplied batches, and meeting new regulatory interpretations. Last year, we tightened control over certain trace-level byproducts after observing minor off-odor complaints in two customer batches. Instead of treating these as isolated events, we upgraded our purification protocols and doubled frequency of finished-goods testing. The outcome: no recurring complaints, improved user trust, and better downstream yields for our largest accounts.

    Investments in process control software, real time analytic tools, and retraining line supervisors have paid off in reduced claims and quicker root-cause troubleshooting. No process ever stands still—each season brings new client requests, regulatory updates, or supply chain shifts. We stay ahead by sharing field wins and setbacks across the organization so solutions scale and improvements embed across all sites.

    Direct Support and Real-World Solutions

    Formulators running scale-ups or validation batches speak most about response time and follow-through. Our support group exists not as an afterthought but as part of the core operating team, drawing on both manufacturing and technical application backgrounds. When questions arise about solubility, pH compatibility, or blending, we bring data from our own lab runs and compare these with production-scale usage from past projects. This approach replaces guesswork with practical help—nobody benefits from slow or generic responses when deadlines loom.

    Sometimes, we even visit customer plants (remotely these days, more often than not) to track down process inconsistencies or confirm line modifications. Documentation from these collaborations gets folded into ongoing manufacturing adjustments and updated tech sheets sent out with future lots. For us, “support” goes beyond checking a box—it means connecting lab data, plant histories, and logistics right through to on-the-ground troubleshooting.

    Shaping the Future: Where Experience Meets Innovation

    Modern chemical markets reward reliability, speed, and adaptability. We do not rest on past performance or limit ourselves to established production modes. Teams across manufacturing, quality, and technical service challenge each other to reduce downtime, catch issues at the start, and push process margins tighter. Investment in process automation lets us dial in even finer tolerances and replicate lab results at commercial scale time after time. The dialogue with our most demanding users remains open, because innovation works best when matched to real market needs—not imagined ones.

    In the years ahead, we see demand for diols like 2-N-Butylpropane-1,3-Diol rising, especially as downstream producers seek to reduce risk, cut regulatory workload, and support safer, more sustainable chemistries. Documented track record, transparent supply chains, and lived-in production routines matter, now more than ever. We keep our focus here, so users can trust that every drum we ship meets more than just a spec—it reflects the collective input from our operators, engineers, customers, and technical partners worldwide. The compound may seem just another entry in a catalog, but every shipment leaves our gate carrying the experience behind it.