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2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate

    • Product Name 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate
    • Alias Ace-2-Cyano
    • Einecs 249-482-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    162535

    Productname 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate
    Molecularformula C13H16N2O2
    Molecularweight 232.28 g/mol
    Casnumber 143193-90-0
    Appearance Colorless to pale yellow liquid
    Purity Typically ≥ 98%
    Solubility Soluble in organic solvents such as DMSO and methanol
    Storagetemperature Store at 2-8°C
    Synonyms 2-[2-Cyanoethyl(phenyl)amino]ethyl acetate
    Smiles CC(=O)OCCN(CC#N)C1=CC=CC=C1

    As an accredited 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, securely sealed, labeled with "2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate, 100 g," hazard symbols and safety information.
    Shipping 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate should be shipped in a tightly sealed container, protected from moisture and light. It must be handled as a chemical substance, following standard regulatory guidelines for transport. Ensure compliance with hazardous material regulations, utilizing appropriate labeling, cushioning materials, and secondary containment to prevent leaks or exposure during transit.
    Storage 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Avoid contact with strong oxidizing agents. Ensure the storage area is equipped with appropriate spill containment measures and compatible chemical labeling. Always follow your institution’s safety protocols and Material Safety Data Sheet (MSDS) recommendations.
    Application of 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate

    Applications of 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate in Industrial Manufacturing

    2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate is a specialized chemical intermediate utilized by leading manufacturers in several advanced sectors. Our experience supplying this material to major global producers informs strict attention to downstream compliance, precise formulation, and validated process performance. We support chemical engineers and industrial formulators working in dynamic product environments.

    1. Photographic Chemicals—Color Developer Synthesis

    Key downstream players in photographic chemistry use this molecule as a secondary amine source in the synthesis of advanced color developers. End-users require high-purity lots for integrating into developer precursors. Industrial process lines adopt our product into aqueous reactions under alkaline conditions to introduce cyanoethyl and anilino functional groups, critical for developer structure. Product stability and lot traceability are maintained per customer batch records and in-line QC analysis.

    Industry compliance standards

    • ISO 9001:2015 for production quality assurance
    • Eastman Kodak Q-Chem protocols for developer intermediates
    • EU Regulation (EC) No 1907/2006 (REACH) for registration and handling
    • OSHA Chemical Hazard Communication Standard 29 CFR 1910.1200

    Typical usage ratio

    • Feedstock concentration: 5–9% by weight of developer intermediate batch
    • Adjusted according to developer type and desired color intensity index

    Downstream process integration

    • Added to batch vessel post-saponification and prior to other color developer additives
    • Introduced at controlled temperature (40–55°C) to prevent hydrolysis
    • Monitored via in-process chromatography for impurity thresholds

    Final product types

    • Color developing agents (e.g., CD-3, CD-4 derivatives)
    • Photo-processing chemical kits for industrial and medical imaging
    • Specialty color developer formulations for aerial and x-ray film

    2. Agrochemical Synthesis—Herbicide Intermediate

    Multinational agrochemical producers rely on this compound in the preparation of substituted aniline intermediates for selective herbicides. The cyanoethyl group enables downstream reactions, including condensation and cyclization steps, to build active molecules targeting broadleaf weeds. All batches pass rigorous impurity profiling, especially for regulatory submissions in markets with strict pesticide controls.

    Industry compliance standards

    • ISO 14001:2015 for environmental management
    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS) requirements
    • EPA 40 CFR 180 for pesticide active ingredient registration
    • National standards for maximum residue limits (MRLs) in target export markets

    Typical usage ratio

    • Feedstock addition: 8–15% by mass in herbicide intermediate synthesis reactions
    • Formulation ratio varies by specific herbicide structure and regulation-driven purity targets

    Downstream process integration

    • Charged at the condensation stage with other substituted aniline or phenoxy precursors
    • Reacted under controlled pH and reflux for targeted condensation
    • In-line spectrometry applied to monitor reaction end-point

    Final product types

    • Nitrile-based pre-emergent herbicide actives
    • Selective weed control agents for grain and rice fields
    • Bulk herbicide intermediates for further downstream derivatization

    3. Pharmaceutical Intermediates—API Synthesis

    Leading pharmaceutical manufacturers source this compound for custom synthesis of advanced medicinal intermediates, notably in the preparation of candidate molecules in CNS and oncology segments. Its functional groups provide flexibility for further derivatization, facilitating amide coupling or esterification under cGMP conditions. Each consignment is lot-certified, fully traceable, and produced under APIs’ relevant quality risk management protocols.

    Industry compliance standards

    • ICH Q7 and Q11 for GMP Guidance in API manufacturing
    • US FDA 21 CFR Parts 210/211 for process controls and batch records
    • European Pharmacopoeia (Ph. Eur.) general monographs for intermediates
    • Chinese GMP for pharmaceutical intermediates production

    Typical usage ratio

    • Intermediary feed: 3–12 mol% of synthesis batch, set by target molecule route design
    • Adjusted based on API step yield and impurity control in multi-stage synthesis

    Downstream process integration

    • Input at initial coupling or late-stage functionalization steps
    • Purified through crystallization or preparative HPLC to remove by-products
    • QC by HPLC and NMR with batch release on customer protocol acceptance

    Final product types

    • Active pharmaceutical ingredient intermediates for CNS and anti-cancer drugs
    • Bulk intermediates for contract research and manufacturing organizations (CRO/CMO)
    • Medchem building blocks for structure-activity relationship research

    4. Colorant and Dye Manufacturing—Disperse Dye Precursors

    Producers of high-performance organic dyes deploy this material in the construction of disperse dye chromophores for synthetic textiles and advanced technical fibers. The unique structure allows tailored color tuning during diazotization and coupling reactions. Our customers require trace impurity levels to meet global textile colorfastness and safety standards, with each delivery accompanied by a detailed analytical CoA.

    Industry compliance standards

    • OEKO-TEX® Standard 100 for harmful substance exclusion in textiles
    • ISO 9001:2015 for colorant production QA
    • EU REACH Annex XVII for restricted amines in colored products
    • ZDHC MRSL Level 3 for textile chemical input management

    Typical usage ratio

    • Incorporation: 7–14% by weight in total dye batch
    • Ratio set by decisive hue strength, dye liftoff, and lightfastness specifications

    Downstream process integration

    • Mixed with other azo or anthraquinone building blocks in diazotization reactors
    • Coupled under acidic conditions for target dye structure
    • Transferred to filtration and drying for dust-fine dispersions

    Final product types

    • Disperse dye powders and granules for polyester and acetate
    • Color concentrates for spun fiber applications
    • Textile grade coloring agents for high-value garments and industrial use

    5. Electronic Chemicals—Resist and Inkjet Ink Formulation

    Electronics manufacturers integrate this intermediate within specialty resists and functional inkjet ink pigment systems, supporting micro-patterning and imaging in PCB and display panels. Its cyanoethyl group serves as a reactive handle during microemulsion polymerization and pigment fixation, facilitating accurate particle size and charge for application-specific resolution. Extensively validated through pilot line trials under controlled manufacturing regimes.

    Industry compliance standards

    • IECQ QC 080000 for hazardous substance process management
    • RoHS Directive (EU) 2011/65/EU for electrical equipment
    • ISO 22900 series for photoresist process specification
    • Cleanroom production certifications (ISO 14644 Class 7 or stricter)

    Typical usage ratio

    • Photoresist and pigment dispersions: 1.5–5.5% by weight
    • Determined by final print or etch resolution and color gamut requirements

    Downstream process integration

    • Added to monomer mix or pigment premix during phase inversion in reactant vessel
    • Post-functionalization and surface stabilization steps implemented as needed
    • Transferred through microfiltration and shear mixing lines for inkjet ink completing

    Final product types

    • Photoresist coatings for PCB imaging
    • High-definition inkjet inks for electrophotographic displays
    • Micro-dispersion colorants used in large format and electronic printing
    Free Quote

    Competitive 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Introducing 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate: Real-World Insights from the Manufacturer

    Our Experience with 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate

    Producing specialty chemicals for the pharmaceutical and fine chemical sectors calls for quality, reliability, and a deep understanding of each product's properties. Over years of manufacturing 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate, we have gained practical experience that goes far beyond textbook descriptions or technical specifications. Laboratories and pilot plants rarely stay satisfied with bare minimum requirements—consistent chemistry, proven repeatability, and practical utility separate useful intermediates from those that cause more trouble than they're worth.

    In our facilities, controlling purity during synthesis of this compound stands as a central focus. Our teams began synthesizing 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate following years of demand for more refined building blocks in high-value synthesis. Unlike some resellers or traders, being the manufacturer lets us monitor each batch from raw material sourcing to packaging, offering insight into not just how but why certain production measures matter.

    Understanding the subtleties of each compound is always critical. Comparing 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate with alternate intermediates, labs often discover meaningful differences that influence reliability and ease-of-handling. Certain functional groups on this acetate provide extra flexibility for downstream reaction steps. The cyanoethyl and anilino motifs open doors to selective functionalization, while the ethyl acetate backbone offers greater solubility and stability compared to more volatile esters. In multi-step synthesis, every hour saved by a predictable intermediate can shave days off a program’s timeline.

    Model, Usage, and Key Attributes

    The core structure of 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate gives it rich usefulness across pharmacological research and specialty chemical development. As actual producers, we have fielded questions from clients concerning solubility, storage, and integration with both classic and modern reaction schemes. Standard models of this product in our line feature a consistent melting point and predictable reactivity profile. Homogeneity is maintained by close monitoring at every stage—from raw input qualification through final crystallization and drying. These details may sound unremarkable, but clients know how off-spec intermediates can derail otherwise smooth operations.

    Customers across North America, Europe, and Asia-Pacific often look for intermediates that avoid the regulatory complications tied to certain restricted precursors. This acetate fills a unique niche. Its cyanoethyl-anilino bridge interacts well in several heterocyclic construction protocols. We have supplied it to support synthesis of various quinoline and indole derivatives where other aniline intermediates failed to meet reactivity or selectivity demands. The acetate moiety offers another benefit: improved handling and storage compared to lower-molecular-weight esters. Unlike methyl or propyl analogues prone to hydrolysis, the ethyl acetate balance brings a slight increase in stability, reducing the risk of by-product formation during transport or shelf storage.

    Why This Compound Matters: Real-World Scenarios

    Downstream users care about more than just theoretical yields. In the practical world of batch chemistry, every batch lost to contamination, inconsistency, or regulatory surprise can cripple product launch targets. Our plant chemists have spent years troubleshooting process bottlenecks for partners working under varied climates and regulatory frameworks. For example, in API research settings, 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate sometimes steps in when direct amination routes falter or when harsher reagents pose EH&S (Environmental, Health & Safety) concerns. The selective reactivity of the anilino group shaves unnecessary side reactions from many well-documented heterocycle formations.

    Production knowledge has been built through pilot studies, failure analyses, and re-optimization. In one case, a global pharma team reported repeated decomposition with alternative phenyl intermediates during high-temp cyclization. Substituting our high-purity acetate solved the bottleneck; not because of textbook chemistry, but because consistent purity and balanced moisture levels led to lasting batch reliability. These practical advantages can’t get fully captured by simple purity specs—they reflect processes continuously improved with real client feedback.

    Some users have tried working with lower-cost substitutes or recycled aniline derivatives. Experience shows that minor impurities migrate downstream, causing unexpected color-forming or yield-depleting side products. The margin for error narrows in upscaled campaigns. We have responded by strengthening quality controls, investing in more responsive analytical equipment, and tracking customer returns at a granular level. Any discrepancy in IR or NMR profiles prompts batch quarantine and full re-inspection—lessons earned through costly recalls and process reversals, not just theoretical QA standards.

    Managing Regulatory and Supply Chain Considerations

    Unlike traders or resellers, manufacturers engage daily with the frontlines of compliance and documentation. Each shipment reflects our direct investment in risk reduction. For buyers worried about controlled substance precursors, 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate gives options to sidestep increasingly restricted raw anilines or nitro precursors without compromising on product development goals. In some markets, new legislation rolls out with little warning, affecting viable synthesis routes and shipment clearance. By taking ownership over the raw input streams and documentation, we stay nimble—an advantage lost with generic intermediates or opaque distributors.

    Clients often comment on supply chain disruptions during periods of high regulatory scrutiny. They value being able to contact laboratories and technical specialists directly. Real root-cause analysis of every supply snag—be it contamination, customs holdups, or mis-labelling—feeds right back into our next production cycles. One case involved a cascading delay triggered by misclassified HS codes at a major Asian port. Our production and export teams collaborated in real-time with local authorities, using batch records and impurity profiles to resolve the impasse without product loss. Experiences like this shape the robustness of our documentation, much more than boilerplate certificates or secondary assurances.

    Handling, Storage, and Shelf Life: What Labs Need to Know

    Laboratory chemists regularly ask about stability, shelf-life, and compatible storage for 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate. Working as the actual manufacturer, we’ve tested formulations under various humidity and temperature conditions—well beyond the standard accelerated aging checks. The ethyl acetate backbone brings a reliable mix of volatility and resistance to premature hydrolysis, especially under cool, dry storage. Problems with similar acetates (notably methyl or isopropyl) often surfaced during multi-week storage, leading to regulator pushback or the need for urgent re-testing. With steady investment in packaging that keeps out excessive moisture and oxygen, we safeguard batch-to-batch uniformity: not as an abstract promise, but based on hard data from real-world shipments.

    Our drums, carboys, and custom-packed small units employ liners and seals specifically chosen for this type of ester. These packaging details matter—not just for compliance, but because they ensure research or commercial synthesis proceeds without interruption. Chemical packs that once caused orders to stall after customs inspection now deploy with robust certificates of analysis and storage guidance based on regional climate data. Beyond just specs on a label, this attention to packaging and shipping enables our partners to worry less about starting materials and focus more on the chemistry that adds real value.

    Comparison to Related Products: Insights Only Manufacturers See

    Labs regularly inspect a wide range of anilino-acetate and cyanoethyl intermediates looking for the right tool for a synthesis job. As the manufacturer, our perspective is shaped by seeing and solving issues other downstream users may only see after it costs them. For example, methyl aniline derivatives may offer lower initial costs but demand careful handling and often fail stability requirements for export markets like the EU or USA. Similarly, some o-cyanoethylated aniline analogues bring higher reactivity but also increased risk of rapid degradation or regulatory entanglement.

    Years of experience producing 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate in volume have highlighted a few clear advantages:

    We have witnessed plenty of well-intentioned substitutions go awry. A biopharma client once swapped in a lower-purity commercial cyanoethyl-aniline from a trader to save upfront costs. Within days, chromatography columns clogged with unknown byproducts, delaying the project by weeks. Ultimately, the lost time and batch failures dwarfed any perceived savings. These kinds of mishaps drive our continuous investment in closed-loop QA/QC systems and reinforce the importance of thorough documentation tied to every batch.

    Supporting Innovation and Addressing Ongoing Challenges

    Direct feedback from users in chemical development and drug discovery helps refine our manufacturing approach. We don’t sit behind desks pushing inventory; we troubleshoot syntheses, anticipate what side reactions are likely, and flag unusual impurity profiles before they interfere with downstream runs. For those considering new or improved routes, our team offers technical discussions backed by years of analytical and process experience. Not every substitution or process tweak makes the leap from literature to commercial batch without issues—pragmatic adjustments, not theoretical promises, get new chemistry over the finish line.

    Continuous innovation includes adjusting process parameters to respond to new impurity guidelines, like those stemming from the latest USP or EP monographs. Rather than rely on old assumptions, we actively test how new regulations may affect product qualification at customer sites. For example, after stricter nitrosamine risk requirements appeared in European regulations, our QA group re-audited each stage of the acetate’s synthetic process, confirming that all input streams were nitrosamine-free and documenting this with our shipments.

    Sometimes the best support speaks less about the molecule itself and more about the shared risk and reward of long-term partnerships. When we solve problems with customers on the ground, we update our internal playbooks, share lessons learned across teams, and refine documentation that helps not just one company but every partner using our product. Some of the most consequential technical guidance we provide has little to do with marketing language or sales pitches; instead, it involves candid conversations about challenging impurities, pilot plant limitations, or regulatory paperwork that might slow critical research.

    Conclusion: Our Commitment to Long-Term Reliability

    Years of hands-on production of 2-[N-(2-Cyanoethyl)Anilino]Ethyl Acetate have taught us the realities that extend well beyond catalogs and datasheets. The true test of quality in chemical manufacturing rests not just in purity numbers but in the lived experience of those who use our compounds in labs, kilo-plants, and factories every day. Our perspective comes from rounds of continuous improvement—tuning not just for specification, but for reliability, support, and steady partnership in a landscape where regulations and technical requirements keep moving.

    Supplying this acetate means direct accountability for every batch, every analysis, and every challenge. Unlike trading houses or generic suppliers, we stand ready to support problems before they escalate, adapting production and documentation for regulatory, technical, and logistical hurdles that partners actually face. More than a product, this approach embodies a decades-old commitment to building trust—batch after batch, year after year.