|
HS Code |
422126 |
| Cas Number | 109-08-0 |
| Iupac Name | 2-Methylpyrazine |
| Molecular Formula | C5H6N2 |
| Molecular Weight | 94.12 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 139-141°C |
| Melting Point | -23°C |
| Density | 1.063 g/cm³ at 20°C |
| Solubility In Water | Soluble |
| Odor | Nutty, roasted, chocolate-like |
| Flash Point | 37°C (closed cup) |
| Refractive Index | 1.510 at 20°C |
As an accredited 2-Methylpyrazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 250 mL amber glass bottle with a tight-seal cap, labeled "2-Methylpyrazine, 98%," featuring hazard and handling instructions. |
| Shipping | 2-Methylpyrazine is shipped in tightly sealed containers, protected from moisture, heat, and ignition sources. It should be labeled according to hazardous material regulations. Transport follows international and local guidelines, as it is a flammable and irritant compound. Proper ventilation and handling procedures must be in place during shipping to ensure safety. |
| Storage | 2-Methylpyrazine should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible materials such as oxidizing agents. Keep the container tightly closed when not in use. Store in a chemical storage cabinet designed for flammable liquids. Properly label the container and ensure ground and bonding during transfers to prevent static discharge. |
Applications of 2-Methylpyrazine in Industrial Manufacturing2-Methylpyrazine serves as a foundational intermediate in multiple industrial sectors, supporting the synthesis and formulation of high-value, specialty downstream products. As the original chemical manufacturer, we work with global processors to ensure quality, traceability, and reliable application in end-user manufacturing. Below are the primary industrial application segments with compliance, usage, integration, and product insights. 1. Food Flavoring Ingredient ProductionManufacturers in the food additive sector integrate 2-methylpyrazine as a key aroma and flavor precursor in savory and roasted food concepts, especially for snack, cereal, and seasoning production. Precise dosing control is critical to achieve desired note intensity while maintaining food safety and regulatory thresholds. All additions are monitored for consistency in high-temperature processing and subsequent flavor development during baking, roasting, or extrusion. Industry compliance standards
Typical usage ratio
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2. Pharmaceutical API Synthesis Intermediate2-Methylpyrazine acts as a core intermediate in the synthesis routes for certain antitubercular and anticancer pharmaceutical active ingredients. Chemical engineers integrate the material primarily through Friedel-Crafts or acylation sequences in multi-step synthesis. Strict compliance and in-process monitoring assure both the purity of input and the structural integrity of pharmacopeial intermediates. Industry compliance standards
Typical usage ratio
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3. Agrochemical Active Ingredient ManufacturingProducers of crop protection agents utilize 2-methylpyrazine for pyrazine-building-block integration in pesticide, herbicide, and fungicide synthesis. The chemical typically enters the early condensation or cyclization stage and is crucial for generating specific bioactivity profiles. Industry focus includes reduction of environmental impact through traceable raw feeds and compliance with safety tolerances. Industry compliance standards
Typical usage ratio
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4. Polymer Modifier and Additive PreparationThe polymer processing industry incorporates 2-methylpyrazine for functional monomer modification and as a chain-modifying additive, particularly in specialty engineering plastics and resins. This application targets improvements in flame retardancy, anti-static properties, and modification of crystallinity. Producers follow REACH and RoHS directives strictly, maintaining trace impurity levels to prevent polymer yellowing and off-gassing during molding. Industry compliance standards
Typical usage ratio
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5. Specialty Solvent & Heterocyclic Compound SynthesisChemical processors use 2-methylpyrazine as a building block in the manufacture of advanced heterocyclic compounds, including custom solvents and fine chemicals for electronics and analytical applications. These syntheses require controlled conditions for purity and critical documentation for traceability, often under ISO or cGMP guidelines. Integration occurs in facilities with capabilities for solvent distillation and purification. Industry compliance standards
Typical usage ratio
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Years shaping pure 2-Methylpyrazine have taught us what reliable quality truly means for buyers and downstream users. In our production halls, this aromatic compound’s story begins with the raw chemistry—precise reaction controls and high-purity feedstocks make all the difference in yield and clarity. Its chemical structure, C5H6N2, marks it as a simple methylated pyrazine, but its applications and sensory impact run much deeper than the formula suggests.
Every batch of 2-Methylpyrazine we produce meets rigorous standards, with GC assay readings consistently clocking above 99.5%. Pale yellow to colorless in appearance, it comes across the line clean and free-flowing. Its boiling point, in the lower 130s Celsius, lines up with what experienced customers look for in a volatile flavor intermediate. Residual moisture and ash content receive special attention—if you have ever stepped into a flavors lab and watched the impact of a few stray impurities on the finished note, you know why.
Demand for 2-Methylpyrazine draws heavily from flavor and fragrance houses, where it imparts roasted, nutty, cocoa-like tones even at trace concentration. Most of the people who call us for regular shipments run labs concerned about flavor authenticity in food, beverages, and tobacco. Having worked closely with flavorists, we know nothing slows down new product launches like off-notes or inconsistent supply. We maintain clear material traceability and full QA/QC documentation to avoid surprises at the application stage, since real-world experience has shown that small lapses can quickly translate to lost batches and costly trouble-shooting. For those using it in pharmaceutical synthesis or agrochemical intermediates, batch-to-batch uniformity keeps processes efficient and avoids revalidation headaches.
Our manufacturing teams insist on uninterrupted process control, from reaction time and temperature to purification and final packaging. There is nowhere to cut corners when it comes to removing residual solvents or controlling headspace oxygen, because storage stability depends on these steps. Some competitors supply material that tests fine right after packing but drifts in color or titer after transport. We’ve learned to minimize these issues through inert-gas blanketing and using HDPE containers that avoid unwanted leaching or permeability. These are details manufacturers notice, often only after discovering why a new source turned sour. Our logistics team ships with short turnaround times to reduce warehouse holds, a practice that comes from direct customer feedback about previous instability with oxidized batches.
Any lab can print a certificate of analysis, but too many buyers have found that certificates alone don't tell the whole story. We invite site visits, periodic audits, and open discussions about cleaning regimens, storage tank conditions, and in-process control—not just the final product specifications. Experience shows that supply hiccups don't always start with the big issues; sometimes, it’s a cleaning cycle cut short on a transfer line. So we run our QC samples on each drum, not just on bulk tanks, especially before loads headed overseas. Users working in food or tobacco rely on this diligence, since regulatory and sensory hurdles can put pressure on every new launch.
Many industrial users compare 2-Methylpyrazine with structurally similar compounds, such as methylated pyrazines with isomers at other positions, or with ethylpyrazines that offer nuances in flavor or reactivity. The methyl group at the 2-position brings a distinct, round warmth—less piercing than its 3-substituted cousin, and clearly different from 2,3-dimethylpyrazine’s intense roasted note. Customers have learned to spot supply sources that blend lower-cost byproducts or off-cut material to present a superficially compliant aroma. If a batch brings a sharp or musty undertone, chances are high there’s more than just the targeted isomer in the drum. We don’t cut lots or blend residues; everything leaves the line after passing through a set of analytical and organoleptic checks.
Pyrazine chemistry rewards patience and penalizes shortcuts. At scale, exothermic steps during methylation create risks for unwanted polymerization, so our reactors are jacketed for precise thermal control. One missed hotspot, and you get colored tars instead of the bright, pure product customers want. Thorough degassing and staged crystallization help ensure clarity and recognizable aroma strength in every outgoing drum. We continue to invest in catalyst recovery and solvent recycling, not because it looks good on paper, but because we have lived through the real headaches that arise from supply disruptions or charge contamination. More than a decade ago, we lost batches to a faulty distillation column gasket, so we now perform line checks by default before every production run.
Direct experience tells us that traceability and compliance put real constraints on production. For food-adjacent and food-grade supply, every solvent and auxiliary is food-contact-rated, from reaction to drums. Allergen declarations, migration tests, and REACH data sets are kept live and ready for review. We maintain HACCP plans not as marketing, but as a living part of the workflow—because only consistent scrutiny stands up to the questions regulatory auditors ask. For customers producing ingredients for export to North America, Europe, or Japan, our in-house compliance team tracks changes and works through new requirements in advance, sending updated documentation at the batch and container level. Real experience has shown that advance notice and joint audits head off paperwork bottlenecks months down the line.
We know from years of feedback that packaging makes a big difference once materials reach a busy mixing, blending, or application facility. We moved early from metal barrels to heavy-walled food-grade plastics, eliminating flavor taint, ensuring lighter lifting, and cutting spillage from bung corrosion. Each drum comes with easily scannable labeling and lot coding; unloaders can check the material on the spot before it enters a facility. These details matter on the plant floor and have come directly from stories told by customers who had lived through confusing drum swaps or labeling errors before switching to us.
2-Methylpyrazine belongs to a low-to-moderate risk group in chemical processing, but nothing in our shop happens without PPE, air handling, and training. We have handled single-drum to bulk-tanker scale-offs, always controlling emissions and storing away from oxidizers and acid-sensitive materials. Storage in cool, dry, well-ventilated buildings, with spill trays staged and inspected, helps mitigate the real spill risks that infrequent users and smaller crews sometimes overlook. Our crews run through fire and vapor release drills, prompted not by regulations alone, but by a close call with a barrel shift in shipping years ago that nearly led to a hazardous material response.
R&D teams often approach us seeking trial lots or scaled-down packaging, especially when testing new formulations. Instead of standard bulk drums, we have adjusted to include smaller, tamper-evident canisters, since the true value sparks when users can dose accurately and reseal the remainder. This practice began with a university lab group struggling to keep their test stock from spoiling—after visiting and learning their needs, we reworked our filling line to run pilot- and lab-scale volumes. These new practices flow upward, showing established customers what extra service looks like.
We have weathered raw material price spikes, transport bottlenecks, and currency swings—no manufacturer escapes market cycles. Years back, a sharp rise in feedstock cost squeezed smaller factories out of the race; only forward contracts and early bulk purchases allowed steady shipments to carry through. We share honest forecasts with downstream buyers and help them build inventory plans that cushion against seasonal fluctuations. In periods of global freight slowdowns, we lean on regional supply chains and use local partnerships to act faster than the wider global market, so those depending on us avoid some of the harsher shortages or quality stumbles seen elsewhere.
The most valuable improvements in our 2-Methylpyrazine production have come from two-way discussion with customers, not just process optimization inside our gates. We treat every complaint or product-return request as training for future batches. Over the years, we created new analytic standards—like extra microtrace impurity screens or expansion of sensory evaluation panels—by responding to customer QA teams who found note variations or performance drifts that lab numbers alone might have missed. Our technical liaisons work directly with application chemists at customer sites when troubleshooting is needed. We don’t believe in sealing up proprietary methods so tightly that a user can’t see what might affect their final blend or ingredient line.
Having been asked to identify “fake” or tampered samples more than once, we stay vigilant in monitoring trademark infringements and repacked product entering the gray market. Astute buyers have brought in competitive samples that varied widely from true 2-Methylpyrazine profiles—sometimes diluted with higher-boiling solvents or off-grade pyrazines that introduce unwanted odor or performance issues. We've developed and refined our analytic and authentication measures so users can authenticate genuine supply quickly, protecting both our business and theirs from costly surprises.
Some of our best improvements have come from mistakes made and subsequently addressed over years of continuous production. From resolving a feed tank miscalibration during storm-induced blackouts, to riding out a regulatory investigation sparked by an unlabeled allergen claim, we’ve accumulated direct knowledge of the practicalities at every production and supply step. This hard-won expertise informs both the structure of our processes and our communication style: grounded, practical, and equally open about both strengths and the limits of what a pure chemical can deliver.
The industry standard lacks specific guidance for climate-sensitive production of pyrazines, so we took it upon ourselves to implement solvent recovery, renewable utility sourcing, and optimized waste management. We balance solvent life cycle with environmental risk; outdated methods that trade energy savings for potential contamination don’t fit in modern operations. Those investing in green chemistry demand full process transparency, especially as downstream markets for organic and natural flavors gain traction. By auditing our output streams, we quantify residual load, export volume, and recovery efficiency—then share this data with long-term customers when they audit us for compliance with their own sustainability goals.
2-Methylpyrazine has a well-established place in flavor, fragrance, and specialty chemistry, but efficiency and quality improvements continue to present new challenges. We push for tighter process analytics, more robust contaminant removal, and faster logistics tied directly to order cycles. Customers in high-value food and beverage rely on this understanding for smoother launches, but there remain gulfs to cross in harmonizing regulations among global markets. Product labeling, additive lists, and quality testing still change at different rates, making ongoing dialogue and joint adaptation a regular part of our operations. As new technologies appear—continuous reactors, digital QC platforms, sealed sampling systems—we adopt and test in parallel, but never at the expense of material traceability or batch retention.
Some industry players finish the sale and move on, but years of real experience confirm that after-sales support is where reputations are built—or lost. Our customer support includes guidance for storage practices, technical use advice, and repeat sampling driven by user feedback. Many of our strongest business relationships started with a troubleshooting call, not an automated order. Sometimes that support means rapid batch replacement in the wake of a shipping miscue, or collaborative troubleshooting when a customer’s process hits a snag. We aim to build the same trust and technical backbone we would expect ourselves, had the roles been reversed.
Market interest in 2-Methylpyrazine continues to reach beyond traditional flavoring—emerging uses show up in smart packaging, where sensor technologies harness its volatility; others look to its structural backbone in the search for new pharmaceutical intermediates and synthetic building blocks. These applications raise new quality requirements, so we engage with R&D departments to co-develop new grades or adjust specifications where it makes sense. We treat every novel application as an opportunity to learn, adapt, and grow, helping shape an industry that remains at the cutting edge of both chemistry and practical manufacturing expertise.
Manufacturing 2-Methylpyrazine goes far beyond technical recipes or rote specifications. It draws on the collective lessons our teams have gathered, the challenges we’ve survived, and the partnerships we have built along the way. Every bottle, drum, and container shows the sum total of those lessons, and we stand by this material with the practical knowledge only direct manufacturing can provide.