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2-Methylbutylamine

    • Product Name 2-Methylbutylamine
    • Alias sec-Butylmethylamine
    • Einecs 211-234-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    581684

    Chemical Name 2-Methylbutylamine
    Cas Number 109-73-9
    Molecular Formula C5H13N
    Molecular Weight 87.16 g/mol
    Appearance Colorless to yellow liquid
    Boiling Point 89-90 °C
    Melting Point -88 °C
    Density 0.75 g/cm3
    Flash Point 8 °C
    Solubility In Water Miscible
    Refractive Index 1.417-1.419
    Odor Amine-like
    Pubchem Cid 7846
    Iupac Name 2-methylbutan-1-amine
    Vapor Pressure 89 mmHg (20 °C)

    As an accredited 2-Methylbutylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Methylbutylamine is packaged in a tightly sealed 500 mL amber glass bottle, labeled with hazard warnings and chemical identification.
    Shipping 2-Methylbutylamine is shipped in tightly sealed containers, protected from moisture and direct sunlight. It must be handled as a hazardous chemical, commonly under UN 2733 classification. Transport is regulated and must comply with local, national, and international shipping regulations for toxic, flammable substances. Appropriate labeling and documentation are required.
    Storage 2-Methylbutylamine should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as oxidizers and acids. Ensure proper labeling, and keep away from ignition sources, as it is flammable. Use secondary containment to prevent leaks or spills, and store at room temperature for optimal stability.
    Application of 2-Methylbutylamine

    Applications of 2-Methylbutylamine in Industrial Manufacturing

    As the direct manufacturer of 2-Methylbutylamine, we support a wide range of industrial sectors with tailored supply for synthesis and formulation. Below, we outline several key downstream application scenarios common in global industrial manufacturing, detailing usage methods, industry regulations, production process integration, and final output products.

    1. Pharmaceutical Intermediate for API Synthesis

    Pharmaceutical manufacturers utilize 2-Methylbutylamine as a building block for the synthesis of select active pharmaceutical ingredients, especially in antihypertensive and anticonvulsant drugs. The amine group facilitates intermediate formation during multi-step organic synthesis. Our QC ensures low impurity levels required by regulatory agencies. Clients adjust input ratios based on molecular requirements, optimizing yield and purity. We provide documentation for regulatory submissions, supporting audits and customer validation steps.

    Industry compliance standards

    • ICH Q7 GMP Guidelines for Active Pharmaceutical Ingredients
    • 21 CFR Part 211 (US FDA cGMP for Finished Pharmaceuticals)
    • European Pharmacopoeia (Ph. Eur.) monographs for related substances
    • USP General Chapters & Residual Solvent Control

    Typical usage ratio

    • Ranges from 0.1 to 0.5 molar equivalents relative to target intermediate
    • Exact ratio determined by API synthesis route
    • Input mass adjusted to reactant scale-up and purification yield

    Downstream process integration

    • Added at nucleophilic substitution or reductive amination steps in API synthesis
    • Handled in jacketed reactors with nitrogen atmosphere
    • Subjected to in-process QA sampling for amine content and purity
    • Waste collected per pharmaceutical waste handling protocols

    Final product types

    • Finished APIs for antihypertensive drugs
    • Anticonvulsant precursor compounds
    • Synthetic intermediates for central nervous system drugs
    • API reference standards

    2. Agrochemical Intermediate in Herbicide Production

    Leading agrochemical producers source our amine for downstream synthesis of herbicide actives and pesticide intermediates. 2-Methylbutylamine engages in condensation reactions critical to the formation of amide and carbamate linkages. Consistent quality aids process reproducibility, meeting international agrochemical safety and purity requirements. Complexation and quenching steps depend on batch-versus-continuous manufacturing mode.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Certified Processes
    • OECD Principles of Good Laboratory Practice (GLP)
    • REACH Regulation (EC) No 1907/2006 registration and SDS provision

    Typical usage ratio

    • Usually 15–30% by weight in amination or carbamoylation step
    • Adjustments made for mole ratio and reaction conversion efficiency
    • Process engineers optimize based on pilot plant results

    Downstream process integration

    • Fed into batch reactors for condensation with acid chlorides or isocyanates
    • Monitored for exothermic reaction profiles and pH control
    • Residual amine removed by stripping or aqueous workup
    • QC conducted for purity and residual solvent levels

    Final product types

    • Selective herbicide technical concentrates
    • Intermediates for pesticide actives (e.g., carbamates)
    • Formulated agrochemical emulsions
    • Pre-mixed bulk agro intermediates

    3. Corrosion Inhibitor Formulation in Metalworking Fluids

    Global metalworking fluid manufacturers add 2-Methylbutylamine in blended formulations for use as corrosion inhibitors and neutralizing agents. Its secondary amine structure enables reaction with fatty acids and carboxylic derivatives, improving long-term storage stability of cutting fluids and specialty lubricants. Product consistency minimizes batch-to-batch variation in functional properties. Compliance with worker safety and toxicity limits is essential for end-use acceptance in regulated markets.

    Industry compliance standards

    • ASTM D4636 for Water-Based Metalworking Fluids
    • OSHA 29 CFR 1910.1200 (HazCom Standard)
    • SAE AMS3020 for Metalworking Compound Quality
    • DIN 51385 for Testing in Lubricant Applications

    Typical usage ratio

    • Added at 0.5–2.5% by weight in concentrated fluid base
    • Ratio tailored to compatibility with oil phase and additive package
    • Formulation team adjusts based on corrosion resistance QC testing

    Downstream process integration

    • Blended into aqueous or semi-synthetic metalworking fluid bases
    • Processed under controlled agitation to prevent emulsifier breakdown
    • Integrated in final blending prior to canning
    • QA release based on pH stability and storage simulation

    Final product types

    • Industrial cutting fluid concentrates
    • Corrosion inhibitor additives for maintenance oils
    • Machine tool lubricants
    • Dedicated coolant solutions for CNC machining

    4. Rubber Chemical Synthesis for Vulcanization Accelerators

    Rubber processors and tire manufacturers apply 2-Methylbutylamine for preparation of chemical accelerators used in the vulcanization process. The amine reacts with carbon disulfide and other thiol sources to yield fast-action accelerator salts. We maintain stringent control over amine content to ensure reproducible crosslinking and compound consistency. Our documentation supports global tire and elastomer compliance.

    Industry compliance standards

    • ISO 9001:2015 for Rubber Additive Manufacturing
    • ASTM D1349 (Standard Specification for Rubber Compounding Materials)
    • UN GHS/SDS chemical communication for rubber goods
    • REACH Annex XVII for hazardous substance control

    Typical usage ratio

    • Application rates between 1–4 phr (parts per hundred rubber)
    • Ratio varies by rubber grade and target curing speed
    • Optimized to minimize bloom and maximize mechanical properties

    Downstream process integration

    • Mixed with sulfur and activators to form chemical accelerator blends
    • Charged into internal mixers before final compounding
    • Monitored for crosslinking performance in lab-scale vulcanization tests
    • Residual amine traced in finished rubber extracts

    Final product types

    • Automotive tire compounds
    • Industrial conveyor belts
    • Sealing gaskets and weatherstripping
    • Technical rubber sheet goods

    5. Chemical Intermediates for Flavors & Fragrances

    Flavor and fragrance ingredient producers incorporate 2-Methylbutylamine to synthesize specialty amine and aldehyde derivatives used in aroma formulations. The amine undergoes Schiff base formation and further modification, giving rise to key notes for food and fine fragrance blends. Compliance with food safety and allergen labeling regulations is tightly managed, with each batch traceable to origin and impurity profile.

    Industry compliance standards

    • FAFRA (US) and EU FCM No. 10/2011 for food-contact substances
    • IFRA Code of Practice for Fragrance Ingredient Safety
    • ISO 9001 and FSSC 22000 for food ingredient production
    • Food Chemical Codex (FCC) ingredient listing for amine content

    Typical usage ratio

    • 0.2–1.0% by weight in precursor synthesis batches
    • Precise usage based on desired olfactory intensity and target chemical structure
    • Formulators test aroma compatibility prior to scale-up

    Downstream process integration

    • Added in the first step of Schiff base or reductive amination for aroma molecules
    • Carried out under inert gas to preserve product freshness
    • Reaction followed by vacuum distillation for solvent removal
    • Batch Certificate of Analysis issued for each output lot

    Final product types

    • Artificial flavor ingredients for food and beverage
    • Fragrance aldehydes and amines for perfumes
    • Encapsulated aroma compounds
    • Modified food additive bases

    6. Specialty Polymerization Catalysts and Modifiers

    Polymer and resin producers integrate 2-Methylbutylamine as a co-catalyst or molecular modifier in the production of urethane, epoxy, and acrylate resins. Its basicity and molecular structure enable fine-tuning of chain extension, crosslinking rate, and end-group functionality. Much of the value comes from tight control over reactivity index, with compatibility confirmed by rheological and QC checks across batches.

    Industry compliance standards

    • ISO 14001 Environmental Management (chemical industry)
    • ASTM D2559 for Adhesive Resin Preparation
    • RoHS Directive 2011/65/EU for electronics or automotive polymers
    • REACH SVHC communication for downstream users

    Typical usage ratio

    • Input levels from 0.1–0.7% by resin weight, adjusted per formulation
    • Lower loading improves crosslink uniformity, higher loading for rapid gelling
    • Lab assessment determines dosage by end-use viscosity targets

    Downstream process integration

    • Metered into resin kettles after initiator or crosslinker charge
    • Reaction exotherm managed by controlled cooling
    • Monitored for free amine and residual monomer with FTIR/GC-MS
    • End-use product evaluated by adhesion and mechanical property QC

    Final product types

    • Polyurethane insulation foams
    • Epoxy adhesives for electronics or construction
    • Acrylic resin coatings
    • Specialty thermoset molding compounds
    Free Quote

    Competitive 2-Methylbutylamine prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 2-Methylbutylamine: A Closer Look From Our Factory Floor

    Understanding 2-Methylbutylamine in Today’s Marketplace

    Working day in and day out with 2-Methylbutylamine gives a practical perspective on what sets this chemical apart and why customers return for it. Our factory staff see the reality of every batch, from raw material sourcing through final packaging. This isn’t a traded commodity passed hand-to-hand with little oversight; every kilogram leaving our facility comes from tanks and reactors run by people who own the process. That vantage point is a big part of why our team has solid confidence in the consistency and direct traceability of our 2-Methylbutylamine.

    Our version of this aliphatic amine, C5H13N, fills a specialized role between other short-chain amines and their branched cousins. Manufacturing applications rarely need a one-size-fits-all amine. Configurations in its structural backbone mean it delivers a profile you don’t get from simpler n-butylamines or longer, bulkier aromatics. With a clear, colorless liquid and an amine smell that’s sharp enough to stand out, this chemical holds unique value for synthesis processes needing C5 backbone flexibility.

    Process Control and Specifications: Built for Real-World Use

    In our production halls, attention to raw material quality and reaction environment means genuine accountability for each lot we fill. We run frequent purity checks using gas chromatography to make sure main content levels stay above industry benchmarks, and we monitor water and byproducts like aldehydes closely. Most demand stems from customers needing purity above 99%. The amine’s boiling point — 89-91 °C — shapes handling requirements for drum filling, storage, and downstream application.

    Humidity control and nitrogen blanketing keep the product from picking up unnecessary water. Containers and transfer lines use non-reactive materials to avoid trace metal contamination; our lab’s titration and GC-MS data provide the kind of numbers customers check closely. Weight and inert lining, plus a low moisture spec, have a direct impact in electronic chemical and API precursor work. This focus on hands-on, tight-batch quality makes a consistent difference, especially for repeat projects.

    Where 2-Methylbutylamine Fits: A Plant-Level Perspective

    From a practical standpoint, we see the most frequent orders for 2-Methylbutylamine coming from pharmaceutical intermediates, crop protection compounds, and fine chemical syntheses. A good example is its role as a building block for making substituted amides and ureas, particularly where the methyl substitution on the backbone alters reactivity as compared to n-butylamines. In local factories, batch chemists lean on that branched structure when seeking molecules that need steric bulk or slightly reduced nucleophilicity.

    In pharmaceutical ingredient work, our amine sometimes gets chosen over its straight-chain analogues not just because of measurable purity, but because the branching changes metabolic or synthetic by-product profiles. That flavor of specificity matters for customers trying to minimize side chains or chiral impurities during scale-up. Comparing to isomers like 3-methylbutylamine, subtle changes in yield, reaction time, and downstream purification can make a difference over hundreds of kilograms. Our technical service team regularly helps customers explore those distinctions at bench or pilot plant scale, swapping notes and actual samples rather than relying on generic chemical handbooks.

    Direct Manufacturing Touch: What That Means for Quality

    Running production in-house instead of through tollers or external contractors gives direct feedback for batch corrections and a better data trail for audits. Each tank charge, reagent batch, and emptying line gets logged and confirmed on-site by our staff. Because we’re not just handling drums or relabeling material, we upgrade supply flexibility: if a customer needs a special packaging size or lower moisture than typical, we adapt the filling room procedures instead of negotiating with a distant supplier.

    On several occasions, large-volume clients required split shipments with customized drum linings or anti-static protection due to static and amine volatility. Having everything under our own roof meant swapping out filling heads and checking purge profiles on the fly, rather than having to push back delivery times while someone else retools. That kind of responsiveness rarely shows up on a certificate of analysis, but for the customers it matters to, being able to dial in specs is more valuable than generic documentation.

    What Sets 2-Methylbutylamine Apart From Other Amines

    Chemically, the 2-methyl branching sets this molecule apart from both linear butylamines and longer chain pentylamines. The bulk of the methyl group at the second position tweaks both basicity and steric hindrance. Synthetic chemists using it as a nucleophile or starting material see cleaner conversions and reduced side reactions, particularly in alkylation and acylation steps. Manufacturing observations over years show reduced issues with forming high-molecular-weight byproducts compared to n-butylamine and improved storage stability versus isopropyl or sec-butyl analogues with more volatile branching.

    Some may ask about performance in agricultural actives manufacturing — in that field, the behavioral difference is even sharper. Where linear butylamines often cause volatilization losses or quick degradation during formulating, 2-methylbutylamine stands up longer and gives better predictability. Repeatedly, our in-house blends have shown improved retention in soil simulation tests and lower off-gasing during hot weather storage. Over a season’s production, this consistency in physical properties can make a measured impact on product shelf life and application effectiveness.

    Comparing to tert-amylamine or dimethylbutyl homologues, the tradeoff comes in reduced volatility but also easier reactivity control. This allows for less complex containment in customer plants, particularly where vent gas treatment is a concern. Our own filling crew appreciates having an intermediate amine like this with neither the handling hazards of light alkylamines nor the sluggishness seen in longer chains. Bulk tank storage lasts longer, and filter changeouts stay manageable — direct advantages for production schedules.

    User Experience and Handling: An Operator’s Take

    No spec sheet captures what it feels like to shift 2-methylbutylamine around a tank farm or to monitor line cleanliness in the drum-filling bay. The odor is typical for short-chain amines — sharp, but still manageable under basic ventilation. Unlike some cycloalkylamines that push respiratory comfort even through mask protection, this amine clears out of the headspace quickly between transfers.

    From the production team’s perspective, the substance remains a straightforward material: fluid at room temperature, no crystallization under regular conditions, and cleans easily with standard alkaline washes. Pump system compatibility is high due to its low viscosity and non-corrosive nature compared to more caustic amines. This has reduced unscheduled maintenance and extended the lifetime of process seals and gaskets on our lines. In chronic batch operations or for customers pulling full-container loads, that practical edge often outweighs small differences in cost per ton.

    Our plant safety audits highlight two main points: storing in well-sealed steel or HDPE containers to avoid water condensation, and regular vent checks during warm weather. Trained workers recognize that proper PPE — especially gloves and splash goggles — makes a meaningful difference since the amine can irritate skin or eyes. Spills or leaks, though seldom an issue, remain manageable owing to its moderate volatility and water solubility. Neutralization protocols in our plant leverage standard acids, speeding cleanup and getting equipment back online with minimal disruption. From an in-plant reliability standpoint, 2-methylbutylamine earns respect as a solid, predictable performer.

    Traceability and Real-World Accountability

    Any regulatory or customer audit that tours our facility sees our documentation chain — each raw amine batch links directly to its source container, timestamped and signed by local staff. Samples get archived for up to two years, especially where pharmaceutical or custom application business pushes up record-keeping requirements. This traceability builds real trust that batch consistency isn’t just a promise but a demonstrated, repeatable process.

    Working so closely with industry partners has also given our technical team a different view of what real support looks like. Instead of quoting safety data sheets by rote or reading back standard values, we swap plant stories, highlight rare contamination cases, share what works and doesn’t for long-term storage, and help troubleshoot process hiccups. Customers see this as a partnership, not just a sale. Some come back year after year for regular lots, others test an initial shipment and then customize specs based on their changing upstream synthesis. Being a true manufacturer means listening to the plant challenges at every step rather than just talking product features.

    Sustainability and Waste Concerns: Actual Efforts, No Greenwashing

    Everyone working in chemical production today feels the pressure to reduce waste and emissions, whether for regulatory, cost, or plain common-sense reasons. On our line, 2-methylbutylamine gets fractionally recycled from some side streams, capturing excess from filtrate washes and especially from condensate in the vacuum stripping process.

    Instead of venting or neutralizing outright, we capture and reprocess these streams to feed back into the next intermediate tank, trimming both raw input needs and tertiary waste volumes. This closes the loop and keeps disposal from being a sore point, both environmentally and economically. Scrubbers on the vent system cut down ammonia and alkylamine vapors, which not only meets current standards but keeps the air inside the plant more manageable for teams on extended shifts.

    At shipment scale, efficient bulk packing means fewer intermediate containers, degassing steps, and transfer cycles. By consolidating full tank loads and tying shipments directly to customer demand schedules, fewer partial drums sit in storage. This cuts down evaporative losses and keeps the material fresher by the time it reaches the user’s feed tank. While there’s still room for further improvement, the routines we keep in manufacturing actually show up on the plant floor, in both scrap rate reductions and real dollars saved over the year.

    Regulatory and Analytical Realities: On-Site Verification

    As a manufacturer facing routine external audits, we approach compliance as a regular, controllable part of daily life rather than a distant hurdle. Our 2-methylbutylamine batches get sampled in-line for impurity content and final drum fills; documentation lives onsite, not locked in offsite archives. Purity, water, and volatile content checks run right before loading so customers get actual readings rather than aged paper specs.

    Requests for additional quality data often come in, sometimes tied to custom registration or European REACH dossiers. We give in-plant, real-world answers because we’re the actual source, not relying on brokered paperwork or post-hoc certificates. Due to increasing international attention on trace amines and byproducts, we maintain low detection limits on key impurities such as secondary amines and residual solvents. Customers with higher purity demands — biopharma, electronics, or specialty polymers — have direct access to our analytical team to talk through results, not just see them as numbers.

    Local regulators drop by our shop floor without much advance notice. This keeps everyone tuned up, from the forklift drivers to lab technicians. The outcome: no shortcuts, minimal rework, and a comfort level with third parties observing procedures firsthand. This transparency shapes lasting supply relationships and makes sure the amine isn’t just fit on paper, but in practice.

    Challenges and Opportunities: A Manufacturing Veteran’s Thoughts

    Chemical manufacturing isn’t glamorous, but it rewards hands-on know-how and team consistency. Watching 2-methylbutylamine drum after drum head out to customer sites each month, real issues and opportunities stand out. Batch reproducibility, raw material supply, and plant reliability stay top of mind. Sometimes, global logistics create delays outside our control — a storm closes a port, a supplier pauses shipments for maintenance. The response relies on years of plant scheduling experience, backup supplier contacts, and the ability to adjust production priorities.

    Another challenge: real-world handling hazards. Even with modern safety controls, amines carry flammability and toxicological risks if managed carelessly. Routine spill drills, emergency neutralization lines, and frequent worker safety refreshers remain essential. Our operation favors functional, protective habits over paper compliance. People in the plant know the smell and behavior of the amine well — a spill or leak doesn’t go unnoticed, and fixation on continuous improvement keeps the risk profile in check.

    As chemical end markets shift, fresh application demands naturally pop up. Over the last few years, more start-up companies and research labs have turned to us for non-standard grades, specialized moisture levels, and tailor-made blends. The process of adapting these customizations — sometimes just a minor tweak to the distillation profile, other times a full formulation test — stretches product knowledge but also keeps us engaged and learning. For both established bulk buyers and these emerging innovators, direct factory experience and equipment access mean solutions happen on practical timelines.

    Direct Factory Communication: Fostering Long-Term Value

    Open lines between our production supervisors, lab techs, and customer teams have saved both parties costly delays more times than we can count. Whether clarifying an order spec at midnight or tracking a minor impurity uptick, real conversations solve problems. For our customers, the knowledge that there’s a live team behind every batch — with the authority to fix things — beats anonymous email exchanges or the frustration of waiting days for answers from a distant broker.

    This practical, embedded approach doesn’t just streamline troubleshooting; it builds mutual trust. Customers are more comfortable planning their own schedules and launches, knowing they can reach the people filling their orders. Our regulars see the same faces at industry events and site tours, cementing a relationship that thrives on actual delivery rather than promises.

    Supporting Innovation: Working With Customers To Get Results

    Over time, customers from a wide variety of sectors — pharma, agriculture, electronics — have challenged us with questions that lead us to tweak our production process or testing methods. The 2-methylbutylamine we make today runs purer, with better control of trace methylated analogues, than it did five or ten years ago. Each feedback loop, whether from a plant incident or a formulation hiccup, feeds into product evolution.

    We collaborate on application studies, co-develop isolation and stabilization routines, and jointly review analytical data when something looks off. As new uses emerge — such as niche catalysts for green polymerizations or antiviral intermediate production — we open our lab and process rooms for short-batch trials and pilot runs. The willingness to try, fail, and retool on the real factory floor is what keeps the product competitive and the customer base loyal.

    Looking Ahead: Changing Markets, Consistent Manufacturing Values

    Global chemicals markets won’t stand still. Regulatory standards tighten, end users ask for tighter specs, and sustainability targets rise year by year. Our take is simple: direct manufacturing control and clear communication deliver better products and fewer surprises. This approach keeps 2-methylbutylamine efficient, clean, and well understood — not as a commodity, but as a precise, traceable material central to next-generation synthesis challenges.

    Everything experienced on our shop floor translates into how our amine functions for our customers. From reaction yield to safe storage, every adjustment and detail reflects a hard-earned dedication to reliability, safety, and real chemical insight. As the next demand wave arrives, this hands-on, honest method will keep our 2-methylbutylamine — and the products built from it — on solid ground.