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2-Methyl-6-Nitrophenol

    • Product Name 2-Methyl-6-Nitrophenol
    • Alias 2-Hydroxy-6-nitrotoluene
    • Einecs 221-026-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    357704

    Chemicalname 2-Methyl-6-Nitrophenol
    Casnumber 91-56-5
    Molecularformula C7H7NO3
    Molecularweight 153.14
    Appearance Yellow crystalline solid
    Meltingpoint 67-70°C
    Solubilityinwater Slightly soluble
    Density 1.31 g/cm³
    Flashpoint 148.8°C
    Pubchemid 7263
    Smiles CC1=C(C=CC(=C1)O)[N+](=O)[O-]
    Synonyms 2-Hydroxy-3-methyl-5-nitrobenzene
    Storageconditions Store in a cool, dry, well-ventilated area

    As an accredited 2-Methyl-6-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 grams, tightly sealed with screw cap, labeled "2-Methyl-6-Nitrophenol," with hazard warnings and CAS number.
    Shipping 2-Methyl-6-Nitrophenol is shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. The packaging complies with hazardous material regulations, including appropriate labeling (GHS/UN codes). Transportation may require UN-rated containers and documentation due to its toxic and environmentally hazardous properties. Handle with care to avoid spills and exposure.
    Storage 2-Methyl-6-nitrophenol should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and bases. Keep the container tightly closed and protected from light and moisture. Store in a chemical-resistant, clearly labeled container, and handle using appropriate personal protective equipment to prevent exposure through skin or inhalation.
    Application of 2-Methyl-6-Nitrophenol

    Applications of 2-Methyl-6-Nitrophenol in Industrial Manufacturing

    As a direct manufacturer of 2-Methyl-6-Nitrophenol, we supply this high-purity intermediate to downstream sectors with established industrial usage. Our product supports producers in sectors where traceable sourcing, production consistency, and regulatory compliance are essential for global market entry and customer approval. All application scenarios below reflect confirmed, widely adopted industrial practices.

    1. Agrochemical Synthesis – Herbicide Intermediate

    Large-scale agrochemical manufacturers use 2-Methyl-6-Nitrophenol as a key intermediate in the synthesis of certain selective herbicides, particularly those targeting resistant broadleaf weeds. Its methyl and nitro substituents enable precise coupling reactions that lead to the desired active molecule’s formation within multi-step synthesis. The raw material’s purity directly impacts yield and final actives’ consistency, which agencies strictly monitor.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals
    • European Crop Protection Association (ECPA) Manufacturing Standards
    • US EPA FIFRA Raw Material Quality
    • ISO 9001:2015 (process traceability and batch consistency)

    Typical usage ratio

    • Employed at 0.5%–1.2% of the overall batch mass, variable according to target molecule molecular weight and coupling efficiency needs

    Downstream process integration

    • Introduced during the coupling step after chlorination or nitration; often reacts with amines or heterocycles for target active synthesis

    Final product types

    • Selectivity-driven herbicide actives
    • Emulsifiable concentrate (EC) formulations for field application
    • Granular herbicide products (GR)
    • Water-dispersible granules (WG)

    2. Dye Intermediate Manufacturing for Specialty Textiles

    Textile dye manufacturers rely on 2-Methyl-6-Nitrophenol for synthesizing diazo and azo dyes designed for technical fibers and functional fabrics. Its specific nitro orientation enables controlled sulfonation and diazotization, which proves critical for ensuring even color uptake, wash fastness, and light stability in advanced textile processing lines.

    Industry compliance standards

    • REACH Registration (EC No. 1907/2006)
    • ZDHC MRSL v3.1 (Zero Discharge of Hazardous Chemicals Manufacturing Restricted Substances List)
    • Oeko-Tex Standard 100 for textile chemistry
    • ISO 9001:2015 (product and process control)

    Typical usage ratio

    • Applied at 0.7–2.5% of total precursor batch, based on dye chromophore structure and target shade depth; higher ranges reserved for deeper dye tones

    Downstream process integration

    • Added during the azo coupling or sulfonation stage of the dye synthesis line; strict batch monitoring ensures no carry-over of unreacted intermediates

    Final product types

    • Reactive dyes for cotton and cellulosic blends
    • Disperse dyes for polyester and technical polymers
    • High-fastness textile dyes for uniforms, outdoor fabrics, and specialty garments

    3. Pharmaceutical Intermediate – Synthesis of Antimicrobial Agents

    Pharmaceutical ingredient manufacturers use 2-Methyl-6-Nitrophenol as a key intermediate in selected synthetic routes for certain antimicrobial and antiseptic drugs. Process engineers favor this raw material for its established reactivity patterns, enabling clean transitions to downstream nitro reduction and subsequent ring closure. Quality departments monitor trace residuals as required by pharmacopoeial standards.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP–NF Monographs (where applicable at intermediate level)
    • EP (European Pharmacopoeia) for trace impurity thresholds
    • ISO 9001/14001 for upstream process steps

    Typical usage ratio

    • Incorporated at 0.3–0.8% w/w of the target API’s mass; adjustment depends on molecule structure and hydrogenation efficiency

    Downstream process integration

    • Supplied to batch reactors for hydrogenation and subsequent heterocycle condensation; validated processes ensure low route-specific byproduct formation

    Final product types

    • Intermediate blocks for broad-spectrum antiseptics
    • Antimicrobial APIs used in topical or wound care formulations
    • Finished pharmaceutical grade intermediates for downstream synthesis partners

    4. Synthesis of UV Absorbers for Polymer Additive Markets

    Manufacturers in the polymer additives sector employ 2-Methyl-6-Nitrophenol for the targeted synthesis of UV absorber molecules, optimizing the photostability of plastics and coatings. Its phenolic core and ortho-nitro functionalities enable smooth etherification or esterification with light-stabilizing groups, which downstream process engineers control for long-term UV performance in outdoor or automotive materials.

    Industry compliance standards

    • FDA 21 CFR 178.2010 (Indirect Food Additives: Polymers – limits for stabilizers)
    • EU Regulation (EU) No 10/2011 on plastic materials and articles
    • ISO 4892-2 (Accelerated UV testing for plastics)
    • GMP for Additive Manufacturing (as per polymer sector requirements)

    Typical usage ratio

    • Added at 0.1–0.6% by weight to synthesis batches, interpretation based on UV absorber loading target in final resin and light stability test cycles

    Downstream process integration

    • Reacted in the additive synthesis stage, typically post-nitration, before the introduction of alkoxy or hydroxybenzophenone components

    Final product types

    • Hindered amine light stabilizers (HALS) precursors
    • UV absorber additives for PP, PE, PVC resins
    • Masterbatch concentrates for plastic extrusion and injection molding industries

    5. Electronics Industry – Liquid Crystal Intermediate Synthesis

    Leading electronic chemicals producers use 2-Methyl-6-Nitrophenol for precision synthesis of liquid crystal intermediates. Its molecular structure supports the manufacture of polar-substituted aromatic compounds critical in display backplanes and advanced optical films, where electronic purity and molecular uniformity directly affect screen performance.

    Industry compliance standards

    • IEC 61249-2-21 (Product specifications for liquid crystal materials)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • ISO 9001:2015 (traceability for specialty electronics chemicals)
    • Cleanroom production protocols (compliance per ISO 14644-1)

    Typical usage ratio

    • Charged at 0.2–1.0% of total reactant mass; ratio adjusted for target mesogenic group chain length and electronic properties

    Downstream process integration

    • Dosed at early-stage aryl etherification or esterification step, followed by sequence assembly of liquid crystal building blocks

    Final product types

    • Intermediate blocks for LCD and OLED display materials
    • Liquid crystal mesogens for specialty films
    • High-purity optical-grade chemicals for electronic panel manufacturing
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    Certification & Compliance
    More Introduction

    2-Methyl-6-Nitrophenol: A Closer Look from the Chemical Plant Floor

    Understanding the Substance Beyond a Label

    Most people in the market know a specialty chemical by its trade names, numbers, and a few cold facts. Here on the production side, 2-Methyl-6-Nitrophenol means a lot more than a CAS label or a package checklist. It’s a compound with real functions and problems, with unique quirks that only someone digging it out of the reactor, day after day, ever fully appreciates.

    Our 2-Methyl-6-Nitrophenol—No Substitute for the Real Deal

    We don’t run short orders for resellers or dilute batches for price points—the 2-Methyl-6-Nitrophenol that leaves our gate stands up to demanding, repeated use in specialized work. We know where every input comes from, what each filtration step pulls out, and what the color of a finished drum looks like on a humid day. For every chemist needing something they can rely on, there’s a trail of watched indicators, measured heating schedules, and checked reactions behind each kilogram.

    The Details: What Sets Our Product Apart

    In our hands, 2-Methyl-6-Nitrophenol means a crystalline solid, usually pale yellow, with that notable faint, phenolic odor you notice right away during quality checks. Our typical batch achieves a purity range tested for technical needs—a high threshold so downstream reactions won’t stumble on interferences. We keep water content under serious control, eliminating problems in moisture-sensitive reactions. Particle size distribution is monitored at every filtration step, as customers running continuous processes or sensitive formulations benefit from lot-to-lot consistency.

    Heat and solvents cause headaches for some products, but our team dials in drying at just the right step. We’ve found that tweaking kiln temperature by even a small amount in the last stage helps suppress unwanted color formation or micro-impurities. You see the payoff during customer audits, when their quality teams walk the line and spot the uniformity in every bag and drum.

    Applications (and Why Purity Tells the Story)

    Our customers come from advanced chemical synthesis, fine chemicals, and certain specialized materials segments. Many work with intermediates where reactivity, selectivity, or simply absence of side reactions define the project’s success. We’ve had customers using our 2-Methyl-6-Nitrophenol in the manufacture of dyes, pigments, and particular pharmaceutical building blocks. They talk about polymerization control, consistent reaction times, and minimized cleaning between lots. That only gets possible when our delivered product resists the small but frustrating drift that plagues lesser batches.

    Pain points usually center around reactivity: too many trace metals, off-odors, or uneven melting depresses yields and adds hours to troubleshooting. Our facility’s persistent batch recordkeeping turns claimed purity into lived reality. We’ve seen firsthand how a half-value difference in purity—even on a spec-compliant shipment—affects lab results and repeatability. Contaminants cause side reactions, roughen up downstream steps, and inflate costs. Running a process that produces a steady high-purity material changes the math for anyone relying on final-stage yields.

    Where 2-Methyl-6-Nitrophenol Excels Beyond Traditional Nitro-Phenols

    Many buyers compare our product to more generic nitrophenols or to alternative methylated phenols hoping for better economics. In reality, those materials rarely hit the needed reactivity profile for precision applications. 2-Methyl-6-Nitrophenol features a distinct substitution pattern, which changes its interaction with nucleophiles and other reactive groups. Adding that methyl group at the ortho position, beside the phenol, alters both physical and chemical behavior: the melting point increases, solubility shifts, and the aromatic ring stabilizes under certain conditions. These details aren’t just talk for the chemist—they’re everyday consequences seen in reaction times, work-up purification, and final yields.

    Alternative nitrophenols frequently introduce more color or need extra purification treatments downstream. That’s a cost few in specialty chemicals can afford over the life of a production campaign. Our process, refined by our operators and process engineers, drives out more off-odors and isolates the most desirable melting fraction, cutting time (and headaches) for customers. Test results over dozens of lots have shown not only improved analytical purity but also tighter variance in parameters that matter: color index, water content, and trace metals. This level of performance separates technical-grade material from what comes out of brokers’ bags or unaccredited labs.

    Manufacturing Approach: Rigorous Inputs, Relentless Testing

    In our facility, the story starts from feedstocks. We screen suppliers with real audits, not just paperwork. Our purchasing team checks every solvent, every acid, for its exact match with our historic production files. We lock in continuous improvement cycles on reaction monitoring—at any moment, production workers may spot a small abnormality in color or filtration rate, sparking an immediate investigation. Batch logs flag anything suspect, and our lab staff double-checks before a shipment ever leaves site.

    We test with modern methods. Our analytical team runs HPLC and GC, but practical experience trumps even the fanciest chromatograms. When a tank’s odor seems slightly strong or its shade drifts, we pull extra samples and halt the line until root causes are found. The aim never changes: batches with proven, usable performance in the applications that matter to real customers, not passing minimum generic standards.

    Regulatory Insight and Safety Experience

    Handling 2-Methyl-6-Nitrophenol comes with its own set of challenges. The compound isn’t entirely benign; safety must be part of every shipment, every process. Our workers use proper containment, personal protection, and engineered controls. We equip our site with local exhaust, regular leak monitoring, and clear labeling—all to prevent exposure and ensure operators remain healthy for the long haul.

    We align our operation with the most current chemical handling guidelines. Tracking, documentation, and spill prevention go beyond industry averages. Our team doesn’t gloss over safety updates—every procedural tweak gets briefed and followed in the real world. Waste management receives the same scrutiny to keep our footprint as light as possible.

    Differences from Brokered or Batch-Mix Products

    Customers sometimes assume chemical grade is chemical grade. After a few years answering questions from technical leads and researchers who have run back-to-back syntheses, we know better. A brokered batch from a vague source may be labeled as 2-Methyl-6-Nitrophenol, but performance rarely matches ours. Often, those alternatives come with a broader melting range, higher amounts of colored impurities, and inconsistent bulk densities.

    Troubleshooting production with uneven stock places an unnecessary risk on your deadlines. Evaporation, grinding, and mixing often turn up problems others failed to eliminate at the source. Our control over particle size, flowability, and impurity profile reflects hard-won know-how in both process and packaging. It’s not just an issue of playing it safe; our consistency saves your time and reduces scrap while dialing in the best process controls.

    Reliability and Consistency: Lessons Learned

    Manufacturing 2-Methyl-6-Nitrophenol for years has taught our crew to spot trends and manage issues upstream. Humidity swings or a suboptimal solvent batch can throw off a lot. Our recordkeeping isn’t just for compliance—it’s a tool for improvement. Cross-checking every lot reveals long-term drifts that minor single-batch analysis won’t catch. We adjust filtration, drying, or crystallization the moment we find a potential trend, not months down the line after problems reach the customer.

    We’ve developed protocols with built-in guards for trace iron or copper, since upstream carrier chemicals occasionally introduce metals that most labs ignore on routine analysis. These trace metals affect specific reactions in color chemistry and specialty polymer applications; eliminating them protects your investment in both time and expensive processing.

    Supporting Innovation: Why a Dependable Batch Matters

    We hear plenty of stories from those scaling up research—pilot plant chemists running a couple of kilograms, then moving on to 100 kilogram runs. The margin for error narrows at each step. If a single batch underperforms, downstream productivity tanks and questions start flying. Several customers working in dye and organic synthesis have shared stories about failed reactions traced back to variable purity or moisture content from other suppliers. Our team has seen the data: tighter controls on process variables produce improved reproducibility.

    Academic and industrial researchers rely on reference-grade lots to develop new chemistry. An unpredictable, shifting raw material restricts development, preventing reliable scale-up. Our work turns out not just material that meets specification sheets but grants these innovators the confidence to iterate and scale up at speed with predictable results.

    Practicalities of Packing and Delivery

    We’ve learned that even a perfect batch can create problems if packaging goes wrong. Bulk containers allow moisture or atmospheric contamination if handled poorly, which throws off sensitive downstream uses. We switched to thoroughly sealed, moisture-barrier packaging, selecting drums and inner liners that block both water vapor and ambient contamination. Our shipping team uses logs that check seal integrity before and after transit. In the warehouse, every pallet is monitored; if a seal breaks, the whole shipment is quarantined for testing.

    We stagger shipments for customers running long production campaigns. Reserve lots get routine retesting if held beyond baseline shelf life—there’s no sense risking a customer’s run just to move stock. Lab results are shared directly, and we encourage customer audits rather than shying away from scrutiny.

    Environmental Responsibility in Manufacturing

    Manufacturing specialty chemicals responsibly means recognizing impacts beyond our factory fence. We have invested in modern scrubbers, closed-loop solvent recovery, and real-time emission monitoring. Our waste streams undergo careful multi-stage neutralization and handling. Local guidelines inform our disposal, but we also work with third-party auditors to push beyond minimum compliance.

    We address local community concerns with open-door policies and regular site tours for students, regulatory officials, and neighbors. Public transparency helps resolve misunderstandings about what we handle and why. We’re accountable not just to our own workers, but to everyone downwind or downstream of our plant.

    Real-World Challenges: Learning from the Front Lines of Synthesis

    Every production cycle reveals potential trouble spots most outsiders never imagine. Summer humidity, winter cooling rates, or even new personnel on the shift introduce variables that, unchecked, show up in the final product. Patching that up with deeper process control, hands-on operator training, and line-by-line checks brings better product quality. Continuous investment in process hardware means fewer unplanned shutdowns and less waste—an advantage every buyer appreciates after a few disrupted runs.

    Some weeks bring tough calls—accepting a slightly out-of-range input batch or delaying delivery to guarantee spec. Our approach has always been open and direct: we’d rather face a tough conversation than risk damaging a customer’s confidence with a questionable load.

    Putting Experience to Work: The Knowledge That Keeps Quality High

    Long-term success manufacturing 2-Methyl-6-Nitrophenol comes from keeping skilled operators on the lines. Years of hands-on training turn teammates into experts who can spot trends with a glance. Maintaining knowledge sharing between shifts keeps process drift at bay and captures incremental improvements. We actively reward vigilance and improvement suggestions, no matter how small.

    Process records guide both daily preparation and long-term planning. Review meetings focus on actual batch history, not just compliance paperwork, and supply chain team benchmarks both incoming and outgoing stock for better foresight. Problems flagged in the warehouse or logistics department get analyzed by production—not simply passed around in an endless loop.

    Why Quality Control Outperforms Volume Chasing

    The specialty chemical business pushes for volume, speed, and cost reduction. We hold our ground on keeping specifications tight and feedback loops open. Sampling at every stage—raw materials, intermediates, and final goods—grabs issues before drums ever ship. Customers who have tried both the variable, brokered lots and our in-house material consistently report fewer problems and smoother blending into their plants.

    Failing a batch, scrapping a shipment, or rescheduling a delivery sting—there’s no way around it. Chasing tonnage at the expense of control costs more for everyone in the long run. Over decades, our plant culture rewards those who hold to the higher bar, who put traceability and performance above the false economy of cutting corners.

    What We See Ahead: Demand, Trends, and Product Improvements

    Demand for 2-Methyl-6-Nitrophenol keeps climbing as new uses open up in electronics, advanced materials, and specialty coatings. Synthesis specialists push requirements for lower residual solvents and even narrower purity bands. We’re developing process tweaks to bring in new equipment, faster inline testing, and more consistent filtration steps. Each improvement is measured by one simple test: does it help our best customers build a better end product, reduce waste, or ramp up their own production reliability?

    Pressure to align with global green chemistry trends grows every year. We’ve started projects to switch from certain legacy solvents to more environmentally friendly options and invest in recycling wherever material properties hold up. These moves help both environmental and bottom-line metrics; customers increasingly prefer suppliers with measurable sustainability efforts and published improvement milestones.

    Final Thoughts—Experience Over Advertising

    After decades of taking raw chemical inputs and turning them into finished products, the most important lesson remains: genuine reliability beats any promise on a website or marketing brochure. Customers who have shared both routine orders and supply crises with us trust the effort that goes into every drum of 2-Methyl-6-Nitrophenol. They see it in both the big details (high purity, consistent delivery) and small ones (lack of color drift, even crystal habit).

    We keep improving methods, tackle challenges openly, and focus sharply on practical needs from the chemical plant up. That commitment defines our product and draws the line between us and companies content to move someone else’s finished goods around. The difference becomes clear in every synthesis, test, and final result. For those who care about quality—not just compliance—that’s the only reputation worth earning.