Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing sales7@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Methyl-3-Hexanone

    • Product Name 2-Methyl-3-Hexanone
    • Alias Ethyl butyl ketone
    • Einecs 211-380-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    633970

    Chemicalname 2-Methyl-3-Hexanone
    Molecularformula C7H14O
    Molarmass 114.19 g/mol
    Casnumber 5092-34-2
    Appearance Colorless liquid
    Boilingpoint 127-129 °C
    Density 0.786 g/cm3
    Refractiveindex 1.410-1.412
    Flashpoint 29 °C (closed cup)
    Meltingpoint -93 °C
    Solubilityinwater Slightly soluble

    As an accredited 2-Methyl-3-Hexanone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 500 mL of 2-Methyl-3-Hexanone, sealed with a screw cap and labeled with hazard warnings.
    Shipping 2-Methyl-3-Hexanone is shipped in tightly sealed containers, stored in a cool, well-ventilated area away from heat and ignition sources. Compliant with relevant transportation regulations, it is classified as a flammable liquid and handled accordingly. Proper labeling and documentation are provided to ensure safety during handling and transit.
    Storage 2-Methyl-3-hexanone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and incompatible materials such as oxidizing agents. Keep away from direct sunlight. Use secondary containment to prevent spills and clearly label the container. Access should be limited to trained personnel and appropriate fire-fighting equipment should be available.
    Application of 2-Methyl-3-Hexanone

    Applications of 2-Methyl-3-Hexanone in Industrial Manufacturing

    2-Methyl-3-hexanone serves as a specialized intermediate and process solvent in various industrial manufacturing sectors. As a direct producer, we focus on delivering consistent quality and full regulatory support for targeted downstream applications. Below, we outline primary industry uses based on real-world demand and technical disclosure from end-user processing lines.

    1. Agrochemical Synthesis (Herbicides & Pesticide Intermediates)

    Major agrochemical producers select 2-methyl-3-hexanone as a building block for the synthesis of selective herbicide and insecticide active ingredients. It supports specific C7-ketone moiety formations in multi-step alkylation and condensation reactions. The purity standard of this raw material directly impacts the downstream isolation yield of target technical grade agrochemical APIs. Careful ratio adjustment upon scale-up best manages reactivity and minimizes unwanted impurities within strict crop protection product specifications.

    Industry compliance standards

    • FAO/WHO Specifications (JMPR) on Agrochemical Actives
    • ISO 9001:2015 certified quality management
    • REACH registered for substance evaluation
    • Local agricultural chemicals regulations (e.g., EPA FIFRA in the USA, Regulation (EC) No 1107/2009 in the EU)

    Typical usage ratio

    • Usually 0.2–2.0 molar equivalents against target substrate in condensation or acylation steps.
    • Adjusted based on process scale and downstream compatibility with catalyst recovery systems.

    Downstream process integration

    • Entered as a controlled reactant early in process batch reactors for herbicide intermediate synthesis.
    • Role in final step purification to minimize trace residuals in formulated technical material.

    Final product types

    • Technical grade herbicides
    • Formulated pesticide concentrates
    • Wettable powder and emulsifiable concentrate crop protection products

    2. Pharmaceutical Intermediate Manufacturing

    In pharmaceutical ingredient synthesis, 2-methyl-3-hexanone functions as a key intermediate for crafting β-keto derivatives and heterocyclic ring scaffolds found in anti-infective APIs. Downstream chemists use it for both Grignard and reductive amination strategies in proprietary medicinal chemistry processes. Quality documentation and traceability are essential due to registration requirements for drug master files (DMFs).

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • European Pharmacopoeia / USP for relevant intermediate quality, where applicable
    • REACH compliance for imported volumes
    • Trace impurity monitoring under FDA 21 CFR Part 211

    Typical usage ratio

    • Ranges from 0.4–1.5 equivalents in major synthetic steps, adjusted to API route optimization and impurity control requirements.

    Downstream process integration

    • Used as a direct precursor in API side-chain assembly stages or scaffold transformations.
    • Enters closed system reactors with controlled temperature and pH to ensure reactivity profile.

    Final product types

    • API intermediates for oral and injectable drug formulations
    • Building blocks for small-molecule pharmaceuticals
    • Specialty generics and branded compounds requiring β-keto structure motifs

    3. Industrial Solvent for Resin and Coating Formulation

    Coatings and high-performance resin formulators use 2-methyl-3-hexanone as a process solvent due to its balanced evaporation rate and strong solvency for alkyds and nitrocellulose derivatives. It enhances blend uniformity, pigment dispersion, and final dry film characteristics. In performance coatings, it helps modulate viscosity and open time, especially when precise control over surface finish is required on high-speed lines.

    Industry compliance standards

    • US EPA VOC regulations (40 CFR Part 59)
    • EU Regulation (EC) 1272/2008 on classification of chemical substances
    • ISO 12944-1:2018 for paint and coating product quality where solvent residue affects film outcome
    • RoHS and REACH compliance for downstream OEM use

    Typical usage ratio

    • Commonly 3–8% w/w of total resin solids in topcoat or primer formulations.
    • Ratio varies according to targeted drying time and resin system compatibility.

    Downstream process integration

    • Blended into resin base at pre-dispersion stage or immediately prior to pigment milling.
    • Supports viscosity reduction for spray or roller application lines.

    Final product types

    • Automotive OEM coatings
    • Industrial and marine protective coatings
    • Architectural paints and metal primers
    • Printing inks and specialty finishes

    4. Fragrance and Aroma Chemical Synthesis

    Fragrance manufacturers employ 2-methyl-3-hexanone as an intermediate for producing certain branched-chain alcohols and aldehydes that impart green and woody notes in fine fragrance applications. It enters acid- or base-catalyzed reduction and derivatization steps. Purity and trace odor profile remain critical for enabling consistent olfactory attributes in the downstream aroma ingredient portfolio.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • EU Cosmetics Regulation (EC) No 1223/2009
    • ISO 9235:2021 definition and purity requirements for aroma chemicals
    • REACH regulatory registration for supply into the EU

    Typical usage ratio

    • Used at 0.5–5.0% of reaction charge in synthesis of target fragrance molecules.
    • Ratio determined by desired final composition purity and reaction selectivity.

    Downstream process integration

    • Charged into fragrance precursor batch reactors for controlled aldehyde or alcohol formation.
    • Subjected to distillation and fine purification before blending with other aroma compounds.

    Final product types

    • Fine fragrance bases
    • Industrial and functional aroma compounds
    • Perfume and personal care blends
    • Household air care actives

    5. Plasticizer Intermediate Production

    Producers of specialty plasticizers utilize 2-methyl-3-hexanone as a feedstock in esterification reactions with phthalic or adipic acid to build flexible alkyl ester plasticizer molecules. Its molecular branching provides desired low-temperature flexibility and compatibility with polyvinyl chloride (PVC) formulations, supporting the performance of flexible wire and cable insulation as well as synthetic leather.

    Industry compliance standards

    • EU Regulation (EC) No 1907/2006 (REACH) for plasticizer production chemicals
    • ASTM D2124 for phthalate plasticizers in vinyl products
    • EN 71-3 for migration of plasticizers in toys and children’s products
    • ISO 9001:2015 process control accreditation

    Typical usage ratio

    • Used at 1.0–1.2 molar equivalents per diacid in esterification reactors.
    • Ratio selected to optimize plasticizer chain length distribution based on application.

    Downstream process integration

    • Added directly to acid feed tanks for high-temperature batch esterification.
    • Incorporated into continuous reactors with online analytic purity tracking.

    Final product types

    • Specialty plasticizers for flexible PVC
    • Cable insulation and jacketing materials
    • Synthetic leather and coated fabrics
    • Automotive vinyl compounds
    Free Quote

    Competitive 2-Methyl-3-Hexanone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Methyl-3-Hexanone: Direct Insights from the Manufacturer

    Understanding 2-Methyl-3-Hexanone from the Production Floor

    At our facility, the story of 2-Methyl-3-Hexanone begins with carefully chosen raw materials and finishes as a clear, pure liquid ready for the demands of chemical synthesis and industry. As those who turn basic starting compounds into a chemical that sees real use across laboratories, factories, paint shops, and pharmaceutical lines, we know every nuance—each batch, purity level, and shipping run tells a chapter in the experience of working with this molecule. Years on the production floor have brought a solid sense of its value and quirks, especially when placed beside other similar ketones.

    The Building Blocks: Model and Specifications from Our Line

    2-Methyl-3-Hexanone draws interest for its balance of reactivity and selectivity. In daily operations, purity ranks as the central concern: too much water, excess by-products, or even trace metal residues can compromise function. Our model focuses on a specification with high assay—greater than 98%—by gas chromatography, keeping acidity under tight control and maintaining low levels of non-volatile matter. Appearance stays colorless, free from haze, and distillation profiles confirm a narrow boiling point, reinforcing consistently tight product control. Any variation in these figures quickly gets picked up in post-run analysis; even small drifts might indicate early maintenance needs on the distillation columns or feed tank. Our field teams do not rely on certificates alone but check random lots, verifying lot-to-lot uniformity not on paper but in the flask and during actual blending trials.

    Odor and solubility also factor in daily work. 2-Methyl-3-Hexanone brings a subtle, sweetish scent, signaling purity for those who know the warning sharpness of amine or aldehyde tints. It dissolves well in alcohols and ether, less so in water—a property carefully measured batch after batch, because drift here often means contamination. These checks matter: customers making fine chemicals, printer coatings, or special adhesives, depend on each consignment acting the same way in their production lines as it did in our test bench. We adjust equipment and reevaluate feed stocks at the first sign of impurity or functional property slip.

    Real-Life Uses: From Solvent Lines to Complex Synthesis

    In industry, 2-Methyl-3-Hexanone’s job covers a lot of ground. The solvent market picks it up for its balance—powerful, yet not aggressive enough to damage sensitive materials. In our paint and coatings segment, the molecule delivers strong solvency for resins—quickly dissolving ingredients in a mixing tank, then evaporating at a controlled rate so products set just right. Operators in these shops prize not just solubility, but consistent evaporation and low residue. Tougher, volatile alternatives often carry stronger safety and odor issues; 2-Methyl-3-Hexanone gives enough solvency to do the job without as much regulatory or worker hazard.

    In fine chemicals and pharmaceuticals, the value turns toward selectivity. Chemical engineers report that it functions reliably as an intermediate, holding its structure through multi-step reactions that can break down less robust ketones. Hydrogenation, oxidation, and condensation stages all see its involvement, and our customers send back feedback on how small changes in reagent purity can swing yields for complicated molecules. We track this information and use it to inform our quality checks and research. The product’s branched chain often gives higher selectivity and different reactivity from similar compounds, which our own R&D groups leverage in route development.

    In adhesive manufacturing, its use as a controlled-release solvent comes up repeatedly, since both setting time and film flexibility depend on evaporation traits matched to a specific formula. Our technical service team works directly with customers tweaking mixes—sometimes reviewing test lines, sometimes helping troubleshoot a downstream solids problem—pulling from practical plant experience. Its stable boiling range means processors aren’t facing surprises during scale-up, a relief for engineers watching for failed batches due to runaway temperatures or unexpected foaming.

    Comparing 2-Methyl-3-Hexanone to Similar Ketones

    Chemical buyers comparing 2-Methyl-3-Hexanone to hexan-2-one, hexan-3-one, or methyl isobutyl ketone often find differences that matter in real-world production. Hexan-2-one delivers faster evaporation, which can cause early film skinning in coatings or adhesives—fine for some fast-dry processes, but not for applications needing open time. Methyl isobutyl ketone brings stronger odor and flammability concerns, along with regulatory friction in certain geographies. 2-Methyl-3-Hexanone, by comparison, balances performance and safety. Field users tell us that it tolerates higher storage temperatures before drifting off-spec or building Peroxides, giving plant managers more flexibility in warehouse layout and logistics.

    The branched structure gives it a lower freezing point than some straight-chain ketones. In colder climates, this helps during wintertime loading and storage—conventional hexanones can solidify at the bottom of barrels, but 2-Methyl-3-Hexanone stays ready to pump. As original manufacturers, we worry about these flow characteristics; any product that thickens or crystallizes gums the pumps and causes lost hours.

    Methyl isobutyl ketone sometimes appears as a cheaper alternative, but hidden costs pile up: added odor scrubbing, increased ventilation needs, higher insurance premiums. User feedback often highlights fewer complaints on production lines and better acceptance from environmental safety teams with 2-Methyl-3-Hexanone. These factors carry weight not just in the plant, but with regulators and local communities, especially in sites near residential areas. Over decades, the end-users’ reports shape our shift in processes, pushing us toward tighter control over emissions and batch purity—pressure that traders or resellers do not feel the same way.

    Handling, Packaging, and Worker Safety Straight from the Floor

    From daily handling, we know that even the purest batches of 2-Methyl-3-Hexanone need careful stewardship. It carries volatility and flammability in line with most light ketones, so bulk storage demands grounded tanks, reliable vapor seals, and well-drilled staff. Our operations shifted over years to closed-loop drum transfer systems, eliminating common spills and improving air quality for our teams. Leaks don’t just cost dollars—they trigger cleanups, force unplanned downtime, and risk worker health. Training focuses not on checklists, but on drills and supervised practice, giving staff muscle memory for fast, correct reaction if something does go wrong.

    Containers matter. Our drums use food-grade linings for purity-sensitive clients, while standard drums meet industrial solvent norms. Drums and smaller containers ship with tamper-evident closures because even a brief accidental exposure can introduce water, leading to cloudiness or phase separation—issues that slide straight through to the customer and cause returns or lost contracts.

    In terms of labeling and documentation, every container carries key production data: batch number, synthesis date, and full analysis sheets. We push this not just to tick regulatory boxes but because our own shop floor has solved more than one quality dispute by tracing a returned drum back to a specific reactor shift. This level of tracking means issues get resolved quickly, with less finger-pointing between supplier and client. Direct communication between our quality and technical teams and our customers often reveals even small packaging or storage issues before they grow into lost product or reprocessing costs.

    Addressing Challenges and Building Long-Term Reliability

    Seasoned manufacturers recognize that technical data only tells part of the story. On a practical level, shifts in raw material supply, regulatory laws, or even sudden demand spikes put unusual stress on production runs. 2-Methyl-3-Hexanone’s synthesis route draws from both basic and specialty chemistry; minor supply chain hitches can force schedule changes or require substitute reagents. Supply planners in our company work months ahead, building rapport with base material producers and maintaining on-site reserves.

    Batch failures do happen—sometimes due to catalyst fouling, sometimes from contamination. Our approach to minimizing these issues centers on routine equipment audits and team-wide accountability. Instead of waiting for off-spec drums to reach a client, we catch inconsistencies at the bleed-off and sample analysis stage, running parallel pilot batches when something looks off. Near-miss events, such as rapid color change in in-process samples, spark group debriefs. We learn from every anomaly, whether it means updating standard operating procedures or tightening storage temperature thresholds by a few degrees.

    Chemical customers rightly ask about sustainability. Our management teams and process chemists pursue both yield improvement and waste minimization at every stage. Recovered solvents go back into internal processes or off for third-party recycling, but only after careful review of contamination risk. Energy reviews focus on distillation overheads, aiming for lower fuel consumption per ton. In recent years, we’ve introduced alternative green heating sources that bring down emissions in the final product footprint—details we’re happy to share in audits and supplier review meetings.

    As experience shows, raw efficiency rarely means cutting corners. Instead, it’s gradual—process tuning, better automation, and responsiveness to customer stories from the field. Comments from adhesive formulators or resin makers travel fast through our technical services crew; a small tweak to reactor charge order or washdown protocol on our side can save thousands downstream for a client. The feedback loop here matters. Real-world testers often serve up problems that never appear in standard reference books or public datasheets. As the manufacturer, we treat these field reports not as inconvenience, but as critical data for continuous improvement.

    Improving 2-Methyl-3-Hexanone Together with End Users

    In direct supply to chemical users, regular feedback drives product evolution. Some clients request lower water content for critical applications; others push for faster delivery windows tied to just-in-time inventory. Our plant managers balance these targets with safety and legal constraints—not every request can be turned around overnight, but close coordination means priorities get clear and solutions developed in partnership.

    Dominant themes in current user feedback highlight the demand for tighter impurity profiles and more detailed batch analytics. Customers in pharmaceuticals, coatings, and electronics all report that minute variations—on the order of fractions of a percent—can swing yields or change applied film integrity. Rather than relying on standard methods alone, we trial extended analytical screens. Gas chromatography-mass spectrometry and trace metals screening catch what older test batteries might miss. This process often brings early warning of raw material quality shifts, long before obvious failures in finished product show up.

    Packaging customization answers the needs of diverse markets. Some clients working with automated lines shift to returnable intermediate bulk containers, which drop waste and speed unloads. Others running pilot labs choose small volume containers with extra-tight seals. Partnering with users over their entire formulation cycle, we innovate in packaging as much as in chemical content. The drive is always toward practical, measurable customer benefit: fewer lost batches, less downtime, and higher assurance of consistent output.

    Stewardship and Compliance: Going Beyond Minimum Standards

    Direct manufacturing also means carrying responsibility for downstream safety, environmental release, and local impact. Our compliance managers run regular checks well ahead of outside audits, knowing that the next regulatory review isn’t just about conformity—it’s a checkpoint for whether our processes evolve with tightening rules and new findings from workplace science. Chemical synthesis, by its nature, creates risk: moving, storing, and reacting energetic reagents and intermediates bears consequences if mishandled.

    For 2-Methyl-3-Hexanone, air emissions, water discharge, and waste handling drive policy. Over the past decade, we’ve switched away from older, open-tray solvent disposal and moved to closed distillation cycles. Our on-site analytical labs check outgoing waste and released vapor daily, not just in response to legal demand but to catch and fix process leaks before they grow into expensive liabilities. We share environmental performance summaries with major customers and incorporate their input into upgrade cycles, making changes that sometimes run ahead of pending law.

    Worker health and safety receive top-down attention. Personal protective equipment, training refreshers, and periodic ergonomic reviews come as standard. In shift reports, every near-miss or minor spill initiates a root-cause review. We address physical plant stress, such as exposure to repetitive motion or poor ventilation, along with chemical-specific risks. Our insurance partners share data showing that injury rates and claim expenses fall as investments in staff knowledge and safe working tools increase—a proof point we share with both users and stakeholders.

    In some regions, stricter handling and emission rules have led us to redesign synthesis steps or invest in capture and abatement units. These capital outlays bring daily improvements in plant air quality and reduce the probability of headline-grabbing incidents. Our on-staff experts frequently participate in technical committees and standards-setting meetings, adding the nuanced perspective of those who blend regulatory, scientific, and operational experience under one roof.

    The Future of 2-Methyl-3-Hexanone Manufacture

    Developing future applications for 2-Methyl-3-Hexanone rests in part on industry partnerships and in part on our internal research investment. We notice new trends—demand from coatings for low-VOC blends, queries from pharma for high-purity intermediates, and tighter restrictions on process emissions. Our research efforts test alternate synthetic routes, sometimes shifting catalyst or solvent combinations to boost yield or reduce by-products.

    Tuning the product to meet upcoming regulatory or application needs depends on regular dialogue with industry R&D labs and front-line formulators. What matters to an adhesive plant in Southeast Asia—humidity resistance, low odor—might differ from an agrochemical manufacturer in North America searching for tight impurity control. As bulk manufacturers, our flexibility only goes so far—you cannot change a hundred-ton batch overnight—but every quarter, accumulated end-user feedback works its way into plant process changes, lab testing design, and even the order in which we tackle maintenance upgrades.

    Developments in sustainable sourcing and energy use affect planning at scale. Our leaders track market trends for feedstock derived from bio-renewables but balance this with product consistency and long-term supply stability. Small batch tests inform rollouts: nobody wants to jeopardize existing customer processes with unproven innovations. As we keep pace with evolving chemical markets, our knowledge as hands-on makers of 2-Methyl-3-Hexanone puts us in a position to weigh risks and keep quality in focus.

    In Summary: Experience, Reliability, and the Value of Direct Manufacture

    Supplying 2-Methyl-3-Hexanone in a competitive and regulated market takes more than meeting technical specifications. It involves stewardship over every step: raw material selection, production, safety, delivery, and technical service. Our knowledge has formed not just from books or sales sheets, but from solving daily problems, learning from customer feedback, and adjusting to ever-changing market or regulatory needs. Direct experience shapes the consistent product many industries rely on, while ongoing improvement means each shipment reflects a bit more know-how than the last. As original producers, our commitment reaches forward, building reliability into each batch and every customer partnership.