|
HS Code |
314295 |
| Chemical Name | 2-Methoxyphenyl Acetate |
| Molecular Formula | C9H10O3 |
| Molecular Weight | 166.18 g/mol |
| Cas Number | 2204-11-1 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 256-258 °C |
| Melting Point | -21 °C |
| Density | 1.127 g/cm3 |
| Refractive Index | 1.532 |
| Flash Point | 112 °C |
| Solubility In Water | Slightly soluble |
| Smiles | COC1=CC=CC=C1OC(=O)C |
As an accredited 2-Methoxyphenyl Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 2-Methoxyphenyl Acetate, secured with a screw cap and labeled with safety information. |
| Shipping | 2-Methoxyphenyl Acetate should be shipped in tightly sealed containers, protected from light and moisture. Transport as a chemical substance in compliance with local, national, and international regulations. Ensure clear labeling and include appropriate safety documentation. Handle with care, avoiding physical damage or spills. Consult the Safety Data Sheet (SDS) before shipping. |
| Storage | 2-Methoxyphenyl Acetate should be stored in a tightly sealed container, kept in a cool, dry, and well-ventilated area. Protect it from direct sunlight, moisture, and sources of heat or ignition. Store separately from oxidizing agents and acids. Ensure appropriate labeling and compliance with local regulations. Use in a chemical fume hood and always handle with suitable personal protective equipment. |
Applications of 2-Methoxyphenyl Acetate in Industrial Manufacturing2-Methoxyphenyl Acetate serves as a specialty chemical intermediate across several industrial sectors. With proven stability and compatibility, it supports high-value production environments where stringent compliance and processing standards apply. 1. Pharmaceutical Intermediate SynthesisMany pharma manufacturers use 2-Methoxyphenyl Acetate as a protected aromatic precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system therapies and anti-inflammatory agents. Its acetoxy group assists in regioselective functionalization, and careful process control ensures reliable batch-to-batch performance under cGMP conditions. Industry compliance standards
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2. Fragrance Ester FormulationSpecialty fragrance compounders incorporate 2-Methoxyphenyl Acetate for its subtle balsamic-sweet odor and masking qualities. It blends into high-end fine fragrances, personal care scents, and some detergents. Producers monitor allergen and purity profiles as per IFRA and EU cosmetic regulations. Industry compliance standards
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3. Dye and Pigment SynthesisChemical manufacturers employ 2-Methoxyphenyl Acetate in producing select aryl esters and arylamide precursors for high-performance dyes used in textile, leather, and plastics coloration. Its defined reactivity profile supports targeted esterification and coupling reactions under controlled, closed-system conditions. Industry compliance standards
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4. Agrochemical Intermediate ManufacturingFormulators in the crop protection sector utilize 2-Methoxyphenyl Acetate as a building block in select herbicide and fungicide molecule synthesis. Its aromatic structure contributes to effective intermediate functionalization in multi-step, high-yield synthetic routes, subject to strict purity and traceability requirements under agrochemical regulations. Industry compliance standards
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In daily work at our chemical plant, products like 2-Methoxyphenyl Acetate don’t just pass through unnoticed. Each batch runs under the eye of a dedicated team and a disciplined process, where raw materials come together with precision. Our 2-Methoxyphenyl Acetate, which carries the CAS number 4057-60-5, leaves the reactor as a clear liquid. We dial in each reaction so the result matches the high-level purity we promise the industry. With Big Chemistry, every detail counts. Customers in pharmaceutical, fragrance, and specialty chemicals count on accuracy batch after batch.
Experienced chemists know the issues that can pop up with off-spec product—downstream yields drop, waste increases, and timelines slip. That’s why every drop leaving our lines faces GC, NMR, and HPLC checks for purity. In our production runs, the acetate delivers a typical GC purity above 99%, and we keep water content to a minimum with Karl Fischer titration. When bulk containers leave the plant, there’s no worry about unexplained peaks or taint. Every time a new lot is released, a full set of analytical paperwork is backed up by retention samples. Over years of production, this transparency has proven to reduce customer troubleshooting and shorten qualification cycles.
2-Methoxyphenyl Acetate finds its way into more labs and plants than many realize. In the world of fragrances, this molecule gives a clean, lightly sweet note to blends needing subtlety, thanks to its narrow impurity profile. Synthesis chemists in R&D labs reach for it time and again when working on new pharmaceutical intermediates—the acetate group protects functional fragments during multi-step sequences, then cleaves away under mild conditions. The stability of the ether and ester bonds means this compound survives harsh reagents but can be modified when the time’s right. Fine chemicals producers use it as a building block for next-gen polymers, where trace by-products can lead to performance drift or yellowing unless held in check by careful, repeatable synthesis. In our line, special requests come in from customers developing new materials who want test lots—sometimes only a few kilos, other times a full drum or ISO tank. Each new application tells a story about how industrial chemistry and careful manufacturing unlock solutions further down the chain.
Making 2-Methoxyphenyl Acetate demands vigilance. Simple recipes don’t guarantee quality outcomes. Our reactors use jacketed vessels and slow addition—raw material purity is double-checked before charging the system. We track pH, temperature, and reaction time to avoid over-esterification, which might lead to side-products that cause headaches in formulation. Routinely, the lab team takes in-process samples mid-run. Operators have developed a knack for identifying subtlest shifts in color or texture, often finding small tweaks that save hours of downstream purification. Precipitate or phase separation doesn’t just happen in theory—everyone knows a rushed reaction can lead to sticky residues that complicate filtration.
We run multiple grades—standard, high-purity, and low-methanol. Every specification has a direct origin in customer feedback and historical testing. For pharmaceutical work, customers ask for lower levels of residual methanol and non-aromatic impurities. We use vacuum stripping and distillation columns optimized for fine separation, rather than bulk one-pass evaporation. With demand growing from the fragrance and flavor world, we fine-tuned the process to leave minimal carry-over from previous runs—separation is followed by passivated lines, so cross contamination drops below measurable levels. Our lab workers spend extra time analyzing headspace for trace odors, rather than checking boxes, because perfumes and flavors rely on absolute clarity of smell.
For large runs destined for polymerization, customers care more about batch-to-batch reproducibility and headspace purity than appearance alone. That shapes how the team controls drying and warehousing—absorption of ambient solvents is monitored, and every tank is dedicated for compatible products. In hot summer months, staff handle the challenge by blanketing product tanks with inert gas, avoiding micro-oxidation that could alter key parameters on storage.
The production environment makes us face chemical characteristics daily, not only in how we treat the molecule, but also in how we train personnel. 2-Methoxyphenyl Acetate gives off a faint almond-like aroma at higher concentrations, which the experienced nose in the plant recognizes as a signal to check for leaks and fume buildup. We keep safety data sheets updated with the latest findings from actual production experience, noting any new observations from shipment or storage. Spill response drills don't just play out on paper—every operator rotates through practice, ensuring rapid cleanup in the event of misplaced drums or overfills. Over the years, this has proven to save on insurance and regulatory headaches, not to mention building a safer workplace.
Our commitment toward sustainable operation leads us to recover solvents and recycle wash water. Waste streams would otherwise represent cost and compliance risks, so we close the loop in ways that deliver economic return. Regular feedback from environmental audits shapes new protocols. For example, capturing overhead vapors from product transfer lines led to new condenser installations, cutting volatile emissions substantially. Plant neighbors take note when delivery trucks stay on schedule and no odor escapes the facility into surrounding streets.
As a manufacturer, we are often asked about the difference between our 2-Methoxyphenyl Acetate and related esters or aryl acetates. In-house, we test against competitors’ lots and look carefully at every data curve. For example, compared with its close cousin, 2-Ethoxyphenyl Acetate, our product has a slightly lower boiling point, which can make a meaningful difference if you distill under reduced pressure. For chemists working late nights in kilo labs, this detail lets them plan simple purifications instead of troubleshooting stubborn residues at the rotavap.
Another practical advantage comes in avoiding common by-products. Cheaper synthetic routes sometimes leave behind unreacted acetic acid or ether-related impurities; we use a higher-grade catalyst and do an extended wash phase before final filtration. Customers have reported that using lower grade acetates led to off-notes in fragrance or reduced yield in later steps, so they trade up to our process after running small-scale comparison tests. Years of making both the 2-methoxy and 3-methoxy analogues has taught us to look out for subtle differences—they behave nearly the same in simple tests, but diverge quickly in actual application settings. Where high-purity matters—such as active pharmaceutical ingredients or food contact materials—those distinctions are not academic.
We've also seen that 2-Methoxyphenyl Acetate can outperform methyl salicylate or ethyl acetate in certain scenarios. Where salicylates might trigger allergen declarations or regulatory questions, the simpler acetate structure lets product formulators avoid extra paperwork and unwanted complexity in their documentation. In industrial processing, our acetate’s lower viscosity supports smoother transfers and easier pumping, especially important during cold weather deliveries.
Years of supplying 2-Methoxyphenyl Acetate have taught us just how much logistics and packaging affect the customer’s end result. Direct shipment from our site means reduced risk of cross-contamination. Clients come back not only because we keep technical details steady, but also because we solve real-world shipping headaches. We stock sizes from kilo bottles for R&D departments to bulk drums and IBCs for large-scale plants. These are cleaned using dedicated solvent cycles, and each is lined with tamper indicators so nobody worries about ‘mystery’ product.
On the packing line, workers handle every drum as if it’s destined for their own lab. Seasonal temperature swings can wreak havoc on volatile organics, so shipments for temperature-sensitive orders get staged with climate monitoring. Delivery drivers learn about the chemical firsthand, so they can answer questions at the customer dock. Several new clients first called us after receiving leaking or mislabeled product from an importer. Transparency wins their business—we show certificates, test sheets, and history of every batch without excuses. If there’s an issue, we work quickly, sending both replacement stock and fresh data, so plant production never skips a beat.
Raw material costs and transportation push and pull prices, yet our goal remains to provide stable supply, not just cheapest price. Value comes in product quality, sure, but also in knowing that missing a delivery window can grind entire projects to a halt. Every new market we move into brings new handling regs and shipping protocols, so our regulatory staff stays up late reading through new customs rules ahead of big rollouts.
End users don’t just care about paperwork—they want results. Formulators in the fragrance industry notice right away when a new batch of acetate brings off-odors, or doesn’t blend as seamlessly as before. Once, after noticing a rising trend in slight yellowing in customer QC logs, we traced the issue to a minor temperature fluctuation during key distillation stages. Correcting that factor restored optical clarity and let downstream blending lines run uninterrupted. Issues like this rarely appear in textbooks, so the knowledge rolls forward, batch to batch.
Managers share call records from our technical service team, who routinely walk clients through optimal storage and usage tips. For example, storing the product away from direct sun avoids color shifts over long-term storage—one simple change made a meaningful difference for customers managing multi-month inventories. Feedback from this open channel has driven formulation tweaks and product improvements. A few years ago, a R&D partner suggested minor shifts in our neutralization stage to address concerns with trace acidity. After pilot trials, this modification became standard operating procedure, improving both stability and shelf life across our product range.
Process engineers sometimes request alternate packaging or co-shipment with related intermediates. Meeting those needs means adapting warehouse and fulfillment processes, and worker suggestions shape the protocols. Operators found that delivering warm drums in winter climates decreased loading complaints from drivers and receiving staff, which fed into the next year’s shipping SOPs. This sort of on-the-job evolution seems small but cuts costs on damage claims and keeps customers returning.
As regulatory and safety expectations shift, producers face more scrutiny than ever. We regularly update documentation, safety statements, and compliance notes. Our teams manage REACH and TSCA dossiers in-house, rather than relying on generic forms. Experience has shown that early engagement with regulators avoids customs delays and prevents day-long holds at ports. Every destination market, from Europe to Asia, comes with unique forms and paperwork—our staff stays on top of updates, reducing post-shipment surprises.
Global demand sometimes leads to imbalances in supply chains. We learned early not to overpromise lead times during periods of raw material tightness. Backing up sales commitments with stocked inventory smoothes bumps in global freight, especially during port congestion or demand spikes. Our team keeps close watch on carrier schedules and weather impacts, issuing early alerts if delivery times may slip. Customers appreciate proactive updates rather than last-minute apologies.
Our documentation matches local regulation—every shipment goes out with full compliance statements. The data won’t fix every paperwork issue, but it gives downstream manufacturers confidence when they file for their own product registrations. Many customers have told us this removes weeks from their approval process, keeping production lines humming.
Research and development never sleeps. Over the past decade, specialty applications for 2-Methoxyphenyl Acetate have grown. More customers now use it in sustainable materials and green chemistry. Our technical team regularly trials new catalysts to avoid legacy reagents, sharpening our process so it meets both modern and future standards. We source renewable feedstocks where possible and publish batch-level provenance reports, allowing customers tracking the sustainability of their supply chain to keep records clear.
Partnership with end users drives us to develop sustained release forms and alternate grades. For high-purity applications, chemists sometimes request water-white appearance and longer shelf life, prompting our process engineers to test various stabilizers or alternative container linings. Each new request feeds back into production—methods get tweaked, equipment upgraded, and documentation improved. This adaptation lives at the heart of manufacturing, and every improvement helps customers stay nimble in a changing marketplace.
Over the years, producing 2-Methoxyphenyl Acetate hasn’t grown routine. With each batch, the focus remains on product quality, process control, and solving new puzzles brought by real-world application. Sharing technical insights and listening to end users brings value beyond a drum or a shipment—it cements trust rooted in experience and mutual problem-solving.