Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Methoxyhydroquinone

    • Product Name 2-Methoxyhydroquinone
    • Alias 1,4-Dihydroxy-2-methoxybenzene
    • Einecs 206-224-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    333208

    Cas Number 149-76-6
    Molecular Formula C7H8O3
    Molecular Weight 140.14 g/mol
    Iupac Name 2-Methoxybenzene-1,4-diol
    Appearance White to beige crystalline powder
    Melting Point 140-142 °C
    Boiling Point 315 °C
    Solubility In Water Moderately soluble
    Density 1.26 g/cm³
    Pubchem Cid 8767

    As an accredited 2-Methoxyhydroquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Methoxyhydroquinone is packaged in a 100-gram amber glass bottle, tightly sealed, and labeled with safety and hazard information.
    Shipping 2-Methoxyhydroquinone is shipped in tightly sealed, chemical-resistant containers to prevent moisture and light exposure. It should be packed according to hazardous materials regulations, kept away from oxidizers, and labeled as a potentially harmful substance. Shipping typically requires cool, dry conditions and compliance with local and international chemical transport guidelines.
    Storage 2-Methoxyhydroquinone should be stored in a tightly sealed container, protected from light and moisture, in a cool, dry, and well-ventilated area. It should be kept away from incompatible substances, such as oxidizing agents and strong acids. Storage at low temperatures, such as in a refrigerator, is recommended to prevent decomposition and maintain the compound’s stability and purity.
    Application of 2-Methoxyhydroquinone

    Applications of 2-Methoxyhydroquinone in Industrial Manufacturing

    As a direct manufacturer of 2-Methoxyhydroquinone, we supply this specialty intermediate to key sectors operating in stringent regulatory environments. Below we outline specific downstream applications, covering technical compliance, recommended concentrations, integration in production lines, and the precise nature of end-use products.

    1. Advanced Dye and Pigment Manufacturing

    2-Methoxyhydroquinone acts as a critical intermediate for synthesizing quinone-based colorants and dye precursors. Dye manufacturers employ it in controlled oxidation steps or as a functional group modifier when developing high-performance dyes for textiles, digital inks, and plastics coloration. The material’s reactivity with diazonium salts and metal ions supports production of colorfast compounds with precise molecular structures. Our plant supports consistent purity, ensuring batch reproducibility in large-scale pigment synthesis facilities.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 registration for dye intermediates
    • ETAD (Ecological and Toxicological Association of Dyes and Pigments Manufacturers) Responsible Care guidelines
    • ISO 9001:2015 certified quality management systems for colorant intermediates
    • Validated for use under EU Safety of Toys Directive for certain pigment grades

    Typical usage ratio

    • 3–10% by weight in batch pigment or dye precursor formation, adjusted according to target molecular yield and reoxidation cycle requirements

    Downstream process integration

    • Charged during early condensation or coupling stages in pigment synthesis reactors
    • Undergoes controlled oxidation or alkylation with aromatic amines for specialized colorant development
    • Purification and milling as integral steps before product isolation and quality testing

    Final product types

    • Synthetic textile and leather dyes
    • Digital inkjet inks for industrial printing
    • High-stability polymer and plastics colorants
    • Custom pigment concentrates for coatings

    2. Pharmaceutical Intermediate for API Synthesis

    Within the pharmaceutical industry, 2-Methoxyhydroquinone functions as a key intermediate in multi-step synthesis routes for certain active pharmaceutical ingredients, especially for drugs featuring methoxyaniline, quinone, or hydroquinone motifs. Its predictable reactivity and high purity contribute to robust yield control and minimize byproduct formation. APIs using this intermediate include compounds for dermatological, anti-infective, and anti-inflammatory indications. We supply validated lots with comprehensive traceability for formulators operating under cGMP.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP and EP reference monographs for related process intermediates
    • FDA 21 CFR Part 210/211 for pharmaceutical manufacturing controls
    • ISO 9001:2015 traceability and analytical validation

    Typical usage ratio

    • 0.8–3.5 mol equivalents as determined by synthetic scheme optimization for each specific API target

    Downstream process integration

    • Charged at protected halogenation or methoxylation steps, often as a limiting reagent
    • Employed under inert atmosphere to minimize side reactions
    • Subject to controlled quenching and intermediate purification prior to subsequent stepwise transformations

    Final product types

    • Dermatological APIs with hydroquinone derivatives
    • Synthetic intermediates for non-steroidal anti-inflammatory drugs
    • Precursors for antimalarial quinone medicines
    • Specialty excipients for pharmaceutical formulations

    3. Corrosion Inhibitor Synthesis for Metal Surface Treatment

    Corrosion inhibition product formulators utilize 2-Methoxyhydroquinone as a constituent for manufacturing quinone-based organic inhibitors. These molecules provide controlled electron transfer and surface passivation mechanisms to protect ferrous and non-ferrous metals in aggressive service environments. By influencing redox kinetics, the material enables development of both oil-soluble and water-dispersible inhibitor packages that comply with modern industrial coating specifications.

    Industry compliance standards

    • ASTM D6947-15 for corrosion inhibitor performance in hydraulic systems
    • ISO 12944-6 for anticorrosion protective coatings
    • RoHS Directive 2011/65/EU compliance for restricted substances
    • OHSAS 18001 occupational health controls in additive manufacturing

    Typical usage ratio

    • 2–7% by weight in organic inhibitor concentrate, depending on substrate type and exposure mode

    Downstream process integration

    • Introduced during organic synthesis of base inhibitor molecule before final formulation steps
    • Mixed as an additive in waterborne or solvent-based corrosion inhibitor blends
    • Combined with dispersing agents prior to emulsion or microcapsule formation

    Final product types

    • Oil and gas pipeline corrosion inhibitors
    • Industrial metalworking fluid additives
    • Protective primers for steel structures
    • Passivation chemicals for storage tanks

    4. Polymer Crosslinking Agent for Specialty Resins

    In advanced polymer compounding and specialty resins manufacture, 2-Methoxyhydroquinone serves as a redox-active crosslinking co-monomer, particularly for epoxy, phenolic, and polyurethane systems. It facilitates network formation at moderate temperatures, enhancing mechanical durability, solvent resistance, and dimensional stability of the final polymer matrices. This application requires tight control of monomer feed ratios and additive dispersion in industrial compounding reactors.

    Industry compliance standards

    • ISO 11357 (DSC analysis of polymers) for crosslinking confirmation
    • ASTM D949 for crosslinked polymer properties assessment
    • UL 94 flammability rating for end-use polymers
    • Complies with industrial hygiene standards under OSHA 29 CFR 1910

    Typical usage ratio

    • 0.5–2.5 parts per hundred resin (phr), based on total monomer or prepolymer charge, with real-world adjustments by targeted mechanical and thermal properties

    Downstream process integration

    • Dispersed with base monomer solution prior to initiation of polymerization or curing
    • Co-initiated with metal catalysts or oxidants in controlled temperature environments
    • Direct effect on final gel fraction and network density monitored by in-line QC

    Final product types

    • High-performance industrial adhesives
    • Chemical-resistant coatings
    • Epoxy castings for electronic applications
    • Advanced phenolic and polyurethane foams

    5. Fine Chemical Synthesis for Photographic and Imaging Compounds

    Manufacturers in the photographic and imaging sector employ 2-Methoxyhydroquinone as an essential building block for silver halide developer agents and as a modifying reagent in specialty imaging chemicals. Its reducing capability, combined with controlled electron-donating tendencies, enables precision formulation of compounds with specific photographic activity profiles. Strict handling and analytical processes preserve batch consistency across runs and support regulatory demands for purity and impurity limits.

    Industry compliance standards

    • ISO 18911:2010 for imaging material processing chemicals
    • ANSI IT9.11 guidelines for photographic developer purity
    • Environmental standards per EPA TSCA for chemical handling
    • Registration requirements under regional photographic material legislation

    Typical usage ratio

    • 4–12% by dry weight in developer concentrate, tailored by developer activity, batch size, and final formulation matrix

    Downstream process integration

    • Blended into photographic chemical concentrates in initial synthesis steps
    • Undergoes stepwise oxidation and coupling in multi-stage developer production lines
    • Packed in controlled environments to avoid premature oxidation

    Final product types

    • High-resolution photographic developers
    • Imaging plate chemistry for industrial radiography
    • Specialty print developer systems
    • Silver halide stabilizers
    Free Quote

    Competitive 2-Methoxyhydroquinone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Methoxyhydroquinone: Factory Insights on a Versatile Phenolic Compound

    Bringing Years of Chemical Craft to 2-Methoxyhydroquinone

    From the first days on the shop floor, handling phenolic intermediates has demanded precision and a dedication to consistency. Making 2-methoxyhydroquinone exemplifies this tradition. Our team focuses on purity because researchers and production operators count on dependable batch-to-batch quality in everything from specialty polymers to advanced dyes. Most customers ask about clarity, consistency, and how a given batch will handle downstream in formulations or reactions. This is where experience with reaction kinetics and tight process controls makes a difference.

    Molecular Qualities and What Sets This Compound Apart

    2-Methoxyhydroquinone stands out among substituted hydroquinones due to its unique methyl ether group at the ortho position. This small change alters solubility, reactivity, and overall handling profile. Technically, this compound looks simple—its systematic structure is 1,4-dihydroxy-2-methoxybenzene—but in practice, this minor shift in structure impacts both physical properties and downstream application. From plant experience, significant differences show up on the line: more stable crystallization, less stickiness during drying, and a subtle but important difference in odor and handling characteristics compared with regular hydroquinone or methylated analogs.

    Production Discipline and Batch Quality

    Manufacturing steps for 2-methoxyhydroquinone lean heavily on precise ratios, careful temperature ramps, and steady solvent control. Years of refining batch parameters have taught us the effect of small deviations—one misjudged hour during demethylation or oxidation and impurities climb in a heartbeat. Finished product leaves the dryer in off-white to tan crystals. Particle size control means faster dissolution in solvents and simplified downstream use, whether dissolving for a dye intermediate or purifying for analytical chromatography. Consistency in infrared spectrum, melting range, and moisture is checked constantly by our in-house analysts.

    Handling and Physical Properties Observed at Scale

    Specialty fine chemicals never behave in the lab as they do in a 200-kilo reactor. At full scale, 2-methoxyhydroquinone has shown less tendency to cake during long storage compared to unsubstituted hydroquinone. The methoxy group offers better resistance to aerial oxidation, so discoloration and decomposition losses during storage are reduced. This means more stable logistics for customers and less waste during formulation or blending. During loading or sampling, dust levels from this product sit lower and with the right extraction, plant staff find it easier to keep environments clean compared with some other phenolics.

    Applications: Where Chemists Find Value

    Requests come in from teams developing antioxidants, polymer stabilizers, textile dye precursors, even flavor chemistry. The ortho-methoxy group confers SELECTIVITY in reactions where mono-oxygenation is needed. Unlike its cousin, methoxyhydroquinone’s reactivity profile lets chemists tune substitutions—less para reactivity, more ortho-specific reactions. Compared to hydroquinone, it brings a softer redox character to redox catalysts or resin modifiers. Practical uses stem from these chemical traits: gentler reactivity, more specific selectivity, enhanced solubility.

    For dye chemistry, this means more vivid hues and stability in certain acidic or oxidative environments. Polymer chemists often prefer it due to decreased discoloration during extrusion or curing. This specific profile rarely emerges with other hydroquinone analogs that lack the ortho-methoxy group.

    Comparing with Other Hydroquinones and Substituted Phenols

    Years of direct plant analytics and customer troubleshooting highlight the advantages in stability and processing. Compared to the more common hydroquinone, 2-methoxyhydroquinone puts up less of a fight with large-batch oxidation or UV aging, thanks to the electron-donating effect of the methoxy group. Chemically, the methoxy substitution depresses the tendency for oxidative browning—a headache during packaging or blending for certain applications.

    Catechols or resorcinols, both close relatives, bring their own quirks: more water solubility but less thermal stability, and their odor can overwhelm a workspace far faster. Many resin makers and dye formulators have shifted toward 2-methoxyhydroquinone when standard phenolics fail to deliver the required storage or color stability. As for price, it lands mid-range—more than bulk hydroquinone but more accessible than exotic, multi-ring phenolic compounds.

    Quality Certification and Laboratory Experience

    Years in specialty chemical manufacturing train a team to look beyond numbers in a certificate of analysis. Regular batch sampling for 2-methoxyhydroquinone means checking color index by spectrophotometry, quantifying trace organics via GC, and running rapid HPLC for purity benchmarks. Customers rarely find unexplained variance, due to plant controls implemented after hard-earned lessons with earlier phenolic products.

    Quality ties directly to raw material selection—using only known lots of precursors, not off-spec streams. More than a formal procedure, this approach stems from the cost of downtime and rework after a rejected delivery. Many batch losses in early years tracked back to solvent quality or storage conditions; these strictures on supply chain now form part of daily plant checks.

    Packaging, Storage, and Longevity Insights

    Chemical plants perform real-world tests storing 2-methoxyhydroquinone in varied climates. It holds dry in steel-lined drums for over a year with only slight color drift, as long as moisture stays controlled. Pallet stacks in uncooled warehouses suffer little clumping or change provided container seals remain tight. On the production floor, staff appreciate packages that open easily for precise weighing, without the clouds of dust common to similar materials.

    For short-term bulk use, open bags last days on plant benches without appreciable loss in reactivity or color—so customers get a versatile product both resilient in storage and stable in use. This contrasts sharply with more air-sensitive phenols that brown or degrade even in sealed drums.

    Lessons Learned Over the Years

    Decades of chemical manufacturing do not allow shortcuts. Some manufacturers opt to skip extended drying or detailed impurity checks; every time, it returns as a customer complaint about color drift or unexpected reactivity. Care in the methoxylation and oxidation process pays dividends in long-term stability.

    Learning from difficult batches, the practice of keeping reaction temperatures within tight bounds stemmed from costly impurity spikes seen at only a few degrees out of range—no software-based automation ever replaces regular operator checks. Additives that stabilize color during packaging arose after several harsh winters where temperature swings sparked minor browning.

    Common Application Challenges—and How Practical Experience Resolves Them

    One recurring point from customers, especially in dye and resin segments, centers on solubility in various organic solvents. Early batches sometimes left stubborn residue—over the years, process changes tweaked crystal morphology for faster dissolving, with improved particle surface area coming from finer control over crystallization and drying. Cleaning reactors and minimizing lost yield became easier, reducing both downtime and waste.

    For redox-active applications, avoiding trace metal impurities is critical. In-house purification steps use only food/pharma-grade solvents, and trace metal screens catch even minute cross-contamination, lowering unpredictability in catalysis or sensitive electronics manufacturing. These practical improvements stem from direct plant feedback, not theory from datasheets.

    Safety and Operator Handling Experience

    Safe plant practices begin with consistent personal protective equipment and careful product handling. Over repeated campaigns, staff reported less irritation and dust inhalation complaints from 2-methoxyhydroquinone versus stricter phenolics. The product’s lower volatility limits airborne concentrations, and bulk packaging solutions further minimize direct contact. This increases productivity and satisfaction on the floor.

    Environmental Practices and Sustainability Perspective

    Customers more often request reassurance on waste minimization and responsible production. Years of solvent recycling and heat recovery during manufacturing of 2-methoxyhydroquinone have cut hazardous output and fossil energy use. Proper waste treatment—maintaining pH and segregating spent solutions—makes significant difference to local compliance, especially where effluent controls are strict. Staff pride themselves on process improvements that reduce need for harsh oxidizers and lower the risk of accidental discharge.

    By narrowing the solvent panel and improving reaction yields, the plant now recycles significant material back into the process, lowering total waste and environmental burden. Feedback from partners in regulated markets has driven many of these initiatives, leading to a safer workplace and reduced regulatory headaches.

    Final Word: Choosing 2-Methoxyhydroquinone for Specialty Chemistry

    Deciding among phenolic intermediates comes down to more than price or a list of typical properties. Experience shapes judgment on what makes a product reliable in demanding applications. Our plant’s long hours and close attention to reaction details give this compound characteristics that set it apart in tricky downstream chemistry.

    Customers benefit from lower risk of color drift, steadier handling, and refined solubility. For those in search of a balanced phenolic that delivers predictable results in dye formulation, resin curing, or redox processes, 2-methoxyhydroquinone provides a proven tool. The manufacturing journey for this compound, from technical prep to full-scale batches, involves expertise, discipline, and a focus on customer-driven improvements. These accumulated lessons, tested under rigorous plant conditions, deliver stability and performance that serve critical segments across research and industry.

    The best results continue to stem from thoughtful manufacturing wrapped around years of practice, ongoing feedback, and a commitment to tight specifications at every step. 2-methoxyhydroquinone stands as a testimony to what specialty chemical manufacturing can achieve when attention to detail meets practical chemistry.