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2-Ethylfuran

    • Product Name 2-Ethylfuran
    • Alias 2-Ethyl-2-furyl
    • Einecs 205-923-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    589341

    Cas Number 53026-88-9
    Molecular Formula C6H8O
    Molar Mass 96.13 g/mol
    Appearance Colorless liquid
    Density 0.915 g/cm3
    Boiling Point 110-112 °C
    Melting Point -87 °C
    Flash Point 15 °C
    Refractive Index 1.466
    Odor Sweet, ether-like
    Solubility In Water Insoluble
    Vapor Pressure 21 mmHg (25°C)

    As an accredited 2-Ethylfuran factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 mL of 2-Ethylfuran; features a secure screw cap and hazard warning labels for safety.
    Shipping 2-Ethylfuran is shipped as a flammable liquid, classified under UN 1159. It should be transported in tightly sealed, properly labeled containers, away from heat, sparks, and open flames. Adequate ventilation and grounding are required. Shipments must comply with relevant DOT, IATA, or IMDG regulations for hazardous materials.
    Storage 2-Ethylfuran should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and properly labeled. Store separately from oxidizing agents and acids. Use explosion-proof electrical equipment and ensure proper grounding. Avoid storage near incompatible materials to prevent hazardous reactions. Follow all local and regulatory requirements for chemical storage.
    Application of 2-Ethylfuran

    Applications of 2-Ethylfuran in Industrial Manufacturing

    2-Ethylfuran serves as a high-purity intermediate for specialized organic synthesis and is widely integrated into industrial value chains across select advanced sectors. Below, we detail its established downstream applications, regulatory compliance landscape, incorporation process, and resulting product classifications in each major use area.

    1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    2-Ethylfuran functions as a key precursor in synthesizing various heterocyclic building blocks for API development. Its furan ring allows for targeted electrophilic substitutions, suited to controlled multi-step API syntheses under GMP conditions. Manufacturers employ it during route scouting for antineoplastic, anti-inflammatory, and antiviral candidates, reflecting its reactivity and high selectivity in forming pharmaceutically relevant ring systems.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • European Pharmacopoeia (Ph. Eur.) monographs for intermediates and solvents
    • USP NF general chapters applicable to process chemicals
    • FDA 21 CFR Part 211 (Current GMP for finished pharmaceuticals)

    Typical usage ratio

    • 2-Ethylfuran is typically introduced at 0.1–0.9 molar equivalents per API batch. Process chemists adjust loading based on target molecule, route optimization, and impurity profile management in preclinical and scale-up campaigns.

    Downstream process integration

    • Entry occurs in initial heterocycle formation stages, often as the core structural unit. Used in batch reactors under inert atmosphere with halogenating or alkylating agents. Reacted further to attach functional groups, purified in column or distillation steps before utilization in advanced API building.

    Final product types

    • Antiviral drug compounds
    • Oncology API building blocks
    • Specialty heterocyclic screening libraries for pharma R&D
    • Anti-inflammatory prodrug intermediates

    2. Agrochemical Synthesis Intermediate

    The compound is utilized in agrochemical R&D and production for synthesizing novel active ingredients, especially within furan- and pyran-derived pesticide molecules. Its incorporation enhances molecular stability, facilitates downstream modifications to functional pesticide groups, and offers compatibility with established agricultural safety regulations in principle product development.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals (for intermediates in agrochemical synthesis)
    • Regulation (EC) No 1107/2009 (EU pesticide registration)
    • EPA FIFRA compliance (for US market validation)
    • ISO 9001:2015 certified quality management for agrochemical manufacturing

    Typical usage ratio

    • Processes use 2–5% (w/w) relative to primary starting material in synthetic sequence. Ratio depends on target pesticide molecule yield and tolerance to side reactions in multi-step processes.

    Downstream process integration

    • Introduced during construction of substituted aromatic cores, often via Diels-Alder or Friedel-Crafts alkylation with chlorinated intermediates. Followed by functionalization steps, purification, and formulation into technical grade active substance.

    Final product types

    • Insecticide actives based on furan or pyran scaffolds
    • Fungicidal intermediates
    • Novel herbicide molecules for preemergent applications
    • Pesticide development batch samples for regulatory field trials

    3. Flavor and Fragrance Additive Synthesis

    In the flavors and fragrances sector, 2-Ethylfuran appears as a selective precursor for aroma compounds with sweet, nutty, or caramel notes. Its controlled reactivity allows for synthesis of specific furan derivatives meeting safety and organoleptic requirements set by food additive authorities. Producers rely on rigorous analytical verification to ensure compliance and minimize off-odors in final blends for both food and cosmetic fragrance applications.

    Industry compliance standards

    • FAO/WHO JECFA food additive evaluations
    • IFRA Standards (International Fragrance Association)
    • EU Regulation (EC) No 1334/2008 (flavoring substances)
    • FDA 21 CFR §172.515 (approved flavoring agents)

    Typical usage ratio

    • Final usage in food flavor concentrate: 5–80 ppm. During upstream synthesis for furan-type flavor bases, loading is 1–10 mol% relative to the next reactant in catalytic systems tailored for food-grade production.

    Downstream process integration

    • Deployed in controlled low-temperature catalytic coupling to create target aroma compounds. Subsequent isolation, fractional distillation, and GC-MS profiling verify compliance before blending into finished flavor or fragrance formulations.

    Final product types

    • Nutty and caramelized flavor concentrates for bakery and confectionery
    • Sweet, warm base notes for beverage flavor mixtures
    • Furan fragrance bases for high-end perfumery
    • Aroma ingredient samples for regulatory dossiers

    4. Advanced Polymer and Resin Modifier

    Specialty polymer manufacturers employ 2-Ethylfuran for modifying resin architectures in electrical insulation and specialty coatings. Its ability to integrate into polyfurans or act as a crosslinker changes thermal resistance or electrical properties. Strict in-process monitoring ensures final resins comply with safety and performance standards required in the electrical, electronics, or protective coating industries.

    Industry compliance standards

    • UL 94 (Flammability testing of plastics)
    • IEC 60216 (Thermal endurance properties of polymers)
    • RoHS Directive (2011/65/EU for hazardous substances)
    • REACH Regulation (EC) No 1907/2006 for safety data reporting

    Typical usage ratio

    • 2-Ethylfuran is added at 0.5–3.0% by weight to base monomer feed in polymerization. Ratio depends on target thermal, mechanical, and dielectric properties, as well as compatibility with catalyst or base resin formulation.

    Downstream process integration

    • Charged into reactor during oligomer, pre-polymer, or curing steps. May act as a reactive diluent or modifier in in-situ polymerization, then integrated into bulk polymer matrices through controlled heating with precise stoichiometry monitoring.

    Final product types

    • High-temperature resistive coatings for electronics
    • Dielectric insulating varnishes
    • Specialty lamination resins
    • Protective coating intermediates for industrial uses

    5. Specialty Solvent or Extraction Aid in Analytical Testing

    2-Ethylfuran, with its distinct polarity and boiling point, is selectively used in sample preparation protocols for analytical chemistry, including gas chromatography and trace residue extraction. Laboratories value its clean evaporation profile and ability to dissolve specific analyte classes without matrix interference. Purity and trace contaminant control are critical, meeting testing labs’ stringent quality assurance protocols.

    Industry compliance standards

    • ISO/IEC 17025 (Testing and calibration laboratories competence)
    • EPA SW-846 (Test Methods for Evaluating Solid Waste)
    • ASTM D1353 (Standard Test Method for Distillation Range of Volatile Organic Liquids)
    • GMP for analytical laboratory materials

    Typical usage ratio

    • Used at concentrations of 0.2–2.0 mL per 100 mL of extraction medium. Adjustments depend on target analyte class, sample type, and instrumental detection limits.

    Downstream process integration

    • Added directly to extraction flask or sample vial during sample preparation. Involved in liquid–liquid extraction, followed by solvent evaporation and analyte reconstitution for subsequent analysis.

    Final product types

    • Preparation of trace residue test solutions
    • Sample extracts for GC-MS or HPLC analysis
    • Standard laboratory solvent blends for QA/QC workflows
    • Certified reference material preparations
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    Certification & Compliance
    More Introduction

    2-Ethylfuran: A Look Into Our Production and Unique Qualities

    Understanding 2-Ethylfuran From A Manufacturer’s Perspective

    Over the years, working directly in chemical manufacturing, I have seen shifts in demand for specialty building blocks, and 2-Ethylfuran continues attracting attention in both commercial and academic sectors. Unlike many commodity chemicals, this substance draws interest for its performance as an intermediate, its reactivity, and the range of applications made possible by its unique structure. Produced in our facility to ensure purity and consistency, 2-Ethylfuran stands out among the furans and ethers we regularly synthesize. With its ethyl side chain at the 2-position on the furan ring, this compound opens doors for synthetic strategies unavailable with simple furans or substituted phenolics.

    Model And Specifications

    The chemical profile centers around the furan ring, with an ethyl group bonded at the 2-position. Each batch rolling out from our reactors undergoes rigorous analysis—GC and NMR validations provide reliability, so research and formulation groups downstream receive material that consistently matches the high standards demanded by pharmaceutical, agrochemical, and specialty materials labs. 2-Ethylfuran appears as a colorless to pale liquid, volatility stays comparable to similar low-molecular-weight ethers, and its odor—subtle and characteristic—signals both authenticity and chemical integrity. Typically, we deliver it in sealed high-integrity drums or bottles, purged with inert gas to maintain product quality during storage and transit. In every step, stringent controls address both purity and moisture content, two critical factors that can affect downstream results.

    Application Experience and Use in Synthesis

    I have witnessed teams in R&D appreciate the reactivity of 2-Ethylfuran in forming heterocyclic frameworks or as a masked synthetic intermediate. Its relative stability means research chemists can handle it without undue precautions, beyond general best practices for ethers and volatile organics. This allows users to exploit the ethyl side chain as a synthetic toggle—whether as a point of functionalization, a handle for cross-coupling, or a source of selectivity in ring-opening protocols. Seasoned chemists sometimes comment on its favorable boiling point, which makes both removal and fractionation easy and predictable.

    Small-molecule synthesis often calls for building blocks that introduce subtle changes to molecular scaffolding. From experience, 2-Ethylfuran enters reactions smoothly under Friedel-Crafts alkylation, ring-closing reactions, or oxidation protocols. Its electron-rich furan ring serves as a platform for diversification, and the ethyl group at the 2-position provides extra steric and electronic tuning. Peers have used 2-Ethylfuran as a phase modifier, flavor intermediate, and as a test substrate in academic method-development. Its volatility means that careful temperature control minimizes product losses, and our packaging supports controlled withdrawals for reproducible batch-to-batch processing.

    Differentiating 2-Ethylfuran From Other Furan Derivatives

    I have handled dozens of furan derivatives—methylfurans, furfural, tetrahydrofuran among others. Each possesses a different balance of polarity, volatility, and chemical reactivity. 2-Ethylfuran separates itself from the group with the unique placement of its ethyl group, supporting specialty synthesis while maintaining manageable hazard and handling characteristics. Unlike 2-methylfuran, for example, the extra carbon on the alkyl side chain shifts its reactivity and boiling point, which impacts its suitability in multi-step syntheses or downstream chemical processing.

    Its comparably lower water solubility—relative to some oxygenated furans—allows chemists to leverage it in biphasic systems and non-polar solvent matrices. I have seen customers replace certain less selective alkylfurans with this product when the goal is reducing cross-reactivity or achieving tighter process tolerances. As a manufacturer, our feedback loop comes from these end-users, who report improved product isolation or selectivity when switching to 2-Ethylfuran in their patented methods. This niche performance edge is rarely visible in catalog data, but it becomes evident through results obtained on the bench.

    From the viewpoint of a working chemist, 2-Ethylfuran’s furan ring is less prone to aggressive side reactions than more electron-rich systems, reducing byproduct formation. We routinely confirm that our final product limits peroxide formation and impurity carryover, supporting the safety and reliability that process labs value.

    Commitment to Quality, Transparency, and Expertise

    In our facility, nothing replaces direct oversight. I spent years optimizing the conditions that yield high-purity 2-Ethylfuran, sometimes running dozens of trials before identifying the most effective catalyst combination and purification strategy. Small changes—choice of solvent, temperature ramps, distillation cut points—affect both throughput and impurity profile. Every year, our team revisits these process conditions, integrating external feedback and new analytical tools to further tighten specifications and reduce waste.

    We do not make vague claims on purity or performance. Our customers, ranging from multinational companies to university spinoffs, base project success on material reliability. Feedback pointed us toward regular lot-review summaries. Each outgoing shipment now travels with a complete quality report, including trace impurity data and independent confirmation of the absence of stabilizing additives which might compromise reaction selectivity. We learned—often from real process failures elsewhere—that unreported stabilizers or trace impurities can derail gram-to-kilo scaleups, so we keep the process simple and fully transparent.

    Maintaining a sharp focus on safety, we adopted continuous vapor-phase and liquid-phase monitoring to reduce exposure risks for our workforce and downstream partners. Flammability testing and peroxide formation studies get repeated every quarter, not just as a regulatory ritual but as a safeguard to our long-term partners and internal teams who depend on accurate risk assessment data. As a result, several new processors credited our data with making the decision to expand their own uses of 2-Ethylfuran—an outcome we take pride in, as the supplier responsible for every stage of production.

    Addressing Market Gaps and Synthetic Challenges

    It is not uncommon to see supply gaps for some specialty furans, especially as research pivots to greener or more structurally complex targets. 2-Ethylfuran sometimes faces these fluctuations as demand outpaces supply from smaller producers or from inconsistent sourcing. Our response comes through active investment in capacity, regular review of precursor sources, and building inventory safety stocks to weather spikes. Feedback from industry showed that abrupt shortages can cost research groups precious time or even derail commercial launches. By managing a domestic and international network of raw material sources, our plant keeps steady output and provides forward-order options so users can count on uninterrupted access.

    There are challenges on the technical side too. Unlike simpler ethers, the 2-ethyl group must be introduced with care—avoiding over-alkylation, minimizing ring cleavage, and controlling isomer formation. These factors can complicate scaleup in other hands. In our operation, process development never stops. Over the past decade, advances in reaction engineering and in-line analytics allowed us to boost yields, trim residual solvent carryover, and control batch reproducibility. Our engineering team partners with customer sites on request, advising on how to store, handle, and efficiently deploy 2-Ethylfuran for both pilot-scale and production runs.

    Environmental and regulatory rules shift constantly, so we keep our compliance team in the loop with every batch run. Our stewardship tracks waste minimization, emission control, and safe byproduct disposal, surpassing regulatory minimums. When international users seek detailed environmental data for downstream licensing, we promptly provide full dossiers covering handling, emissions, and safe process modifications. By keeping this open channel, we help downstream partners design safer, greener, and more robust synthesis platforms.

    Collaborative Approaches for Process and Product Innovation

    As a chemical manufacturer, innovation rarely means solitary invention; it grows through dialogue and joint troubleshooting. Many product enhancements in our 2-Ethylfuran line grew from this cycle—end users reporting trends in performance, flagging solvating or reactivity issues, and even proposing process upgrades from their own engineering teams. We act on these suggestions by running pilot trials and sharing the findings, building trust and tangible improvements into every new order.

    Each application brings its own set of requirements. In formulation chemistry, teams value 2-Ethylfuran’s controlled volatility and ability to dissolve lipophilic actives. In synthetic methodology labs, selectivity and reproducibility take precedence. In our experience, no amount of data replaces the impact of real feedback: “We see less byproduct,” “The material handles well during scale-up,” “Our chromatograms show cleaner separation.” Those comments drive new batch sizing strategies, alternate container choices, and updated packaging protocols.

    Working in partnership with customers, we also develop handling and dosing guidelines tailored to the unique demands of their facilities—whether for continuous addition, dosing into high-pressure reactors, or integration into automated synthesis platforms. Sharing best practices becomes crucial, especially for a substance like 2-Ethylfuran that mixes volatility with selective reactivity.

    Sourcing, Sustainability, and the Long View

    The landscape for specialty chemicals such as 2-Ethylfuran shifts with every new biotech, pharmaceutical, or advanced materials project. Sourcing second-generation bio-based furans opens possibilities for further reducing carbon impact while maintaining chemical performance. Our research partners have shown that green precursors can integrate into existing processes, given robust purification and analytical controls. Our facility now evaluates renewable feedstocks where feasible, and shares results of life cycle analyses with users invested in environmental certifications or green label development. Scaling up bio-based supply lines takes patience. We make incremental investments—testing compatibilities, mapping out the cost-performance ratio, and phasing in changes where specifications allow.

    Sustainability is more than a slogan—customers now call for detailed data on emissions, waste output, and the eco-footprint of fine chemicals. We publish green chemistry benchmarking data for key products, 2-Ethylfuran included, and revise sourcing or process protocols in direct response to environmental assessment findings. While meeting technical targets forms the baseline, we support each purchasing partner with full transparency and technical backup. In a market with tight quality control and long-term research dependencies, such openness fosters both practical and scientific progress.

    Meeting Regulatory and Quality Demands

    Navigating the stringent regulatory environment for intermediates takes vigilance. Every batch of 2-Ethylfuran receives a compliance review before shipment, covering major international requirements and region-specific demands. Inspection teams at our plant match outgoing products to the evolving needs of both developed and emerging markets. We maintain certified and regularly audited facilities, documenting all qualification and quality procedures.

    Traceability stands as a core value at our site. Detailed manufacturing records follow each batch from raw materials to finished product. Our laboratory information systems support queries for historical data, helping customers answer complex quality or audit questions. Challenges sometimes arise: whether due to new market compliance rules or updated regulatory standards. We adjust in real-time—modifying storage, labeling, and shipping protocols to stay ahead of requirements. This ability to adapt, informed by decades of production and compliance experience, provides reassurance in a climate of increasing scrutiny.

    Customer audits now cover not only traditional QA/QC but also supply-chain reliability, emergency communications, and data tabulation. Our staff welcome these interactions as valuable opportunities to refine workflow and technical documentation.

    Responsive Support and Shared Benchmarks

    No two users approach 2-Ethylfuran with the same set of goals. Whether destined for a flavor synthesis campaign, a targeted pharmaceutical intermediate, or as a reactive diluent in advanced resin systems, success depends on communication and shared knowledge. Over time, the most productive customer relationships grow around honest, two-way sharing of both progress and obstacles. We do not treat support as a formality—direct phone and digital access to our technical group ensures users of 2-Ethylfuran receive informed answers, grounded in years of on-the-floor experience.

    Our application scientists live out the reality that data drives improvement. Reports of purity issues, reaction anomalies, or even logistical snags trigger root-cause analysis and, if needed, process improvement. Routine site visits, application seminars, and joint pilot runs cement the dialogue required for research clients putting 2-Ethylfuran to work in novel ways. These collaborations led to process tweaks—changes in shipping conditions, alternate container formats, or scheduling of just-in-time deliveries to quality-driven organizations.

    The Value Of Experience From The Shop Floor To The Lab

    No amount of theory substitutes for learning how a specialty chemical behaves in a real production environment. As a producer, I see the small details—a slight shift in distillation pressure, water ingress during transfer, subtle color changes after storage—that can spell the difference between batch success and unexpected rework. This shop-floor perspective, fused with a commitment to analytical rigor, supports every ounce of 2-Ethylfuran shipped from our plant.

    Process teams rely on robust, fail-safe methods and data that reflect trial and adaptation, not just ideal lab conditions. We take pride in maintaining this standard, integrating direct feedback from partners developing new catalysts, pharma actives, or agricultural chemicals out of our reagents. The incremental improvements—faster delivery cycles, better packaging, or cleaner product specs—don’t come from templated process maps, but years of adaptation to customer needs and honest reporting of results.

    Reflecting on these years in chemical manufacturing, 2-Ethylfuran represents not just a versatile building block but also an enduring example of where rigorous practice, transparency, and customer collaboration yield real innovation in specialty chemistry.