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2-Ethoxybenzaldehyde

    • Product Name 2-Ethoxybenzaldehyde
    • Alias 2-Ethoxybenzenecarbaldehyde
    • Einecs 211-500-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    373375

    Name 2-Ethoxybenzaldehyde
    Cas Number 1566-19-0
    Molecular Formula C9H10O2
    Molar Mass 150.18 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 244-246 °C
    Density 1.079 g/cm3
    Refractive Index 1.540
    Smiles CCOC1=CC=CC=C1C=O
    Pubchem Cid 13496
    Flash Point 108 °C
    Solubility In Water Slightly soluble
    Synonyms o-Ethoxybenzaldehyde, 2-Ethoxybenzenecarbaldehyde
    Ec Number 216-356-7

    As an accredited 2-Ethoxybenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of 2-Ethoxybenzaldehyde, securely sealed with a screw cap and labeled with hazard warnings.
    Shipping 2-Ethoxybenzaldehyde is shipped in tightly sealed containers made of glass or high-grade plastic to prevent leaks and contamination. It should be stored in a cool, dry, well-ventilated area away from incompatible materials. Proper labeling and adherence to transport regulations for hazardous chemicals are essential during shipping.
    Storage 2-Ethoxybenzaldehyde should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from sources of ignition, heat, and direct sunlight. It should be kept separate from strong oxidizing agents and acids. Proper labeling and access control are essential to prevent misuse or accidental exposure. Store at room temperature and avoid moisture to maintain chemical stability.
    Application of 2-Ethoxybenzaldehyde

    Applications of 2-Ethoxybenzaldehyde in Industrial Manufacturing

    As a specialized producer of 2-Ethoxybenzaldehyde, we focus on supporting key industrial sectors that require high-purity aromatic intermediates for advanced synthesis. The following application scenarios outline where downstream manufacturers routinely incorporate this raw material, highlighting compliance expectations, formulation integration, and typical end use across fine chemical, pharma, and specialty material domains.

    1. Active Pharmaceutical Ingredient (API) Intermediate Synthesis

    Pharmaceutical manufacturers utilize 2-Ethoxybenzaldehyde as a core aldehyde synthon when building advanced heterocyclic scaffolds for API production, especially in antihypertensive and anxiolytic compound routes. The compound functions in the key condensation, reductive amination, or Grignard steps during multi-stage synthesis, where its electron-rich aromaticity enables fine-tuned reactivity. QC teams track residual aldehyde by HPLC to comply with strict impurity profiling. Adjustments to loading levels reflect yield optimization and patent-dependent process routes.

    Industry compliance standards

    • ICH Q7 GMP for APIs (International Council for Harmonisation)
    • Ph. Eur. and USP monograph requirements for raw material purity
    • Regulatory Toxicology and Pharmacopoeial trace impurity limits
    • FDA 21 CFR Part 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals)

    Typical usage ratio

    • From 0.1 to 0.8 molar equivalents per reaction step; optimization based on route-specific stoichiometry, impurity risk, and desired conversion efficiency

    Downstream process integration

    • Charged directly during condensation or cyclization steps in synthetic API production lines (batch or flow reactors); integrated with inline nitrogen purging and automated sampling for process control

    Final product types

    • Pharmaceutical bulk intermediates for CNS drugs, anxiolytics, and select cardiovascular APIs

    2. Fragrance Aldehyde Manufacturing

    Flavors and fragrance formulators use this benzaldehyde derivative as a specialty aromatic building block for crafting complex floral and green aldehyde notes. Production chemists employ the raw material in the synthesis of proprietary fragrance accords, ensuring both batch traceability and low residual solvent levels. Downstream processing mandates tightly controlled blending tanks and adherence to allergen labeling frameworks relevant for global markets.

    Industry compliance standards

    • IFRA Standards for fragrance ingredient safety
    • REACH Annex XVII restrictions (EU chemicals regulation)
    • ISO 9235:2013 (Aromatic ingredient authenticity in fragrances)
    • Cosmetic Ingredient Review (CIR) inclusion and allergen reporting

    Typical usage ratio

    • Ranges between 0.02% and 0.25% by volume in fragrance oil concentrates; determined according to olfactory intensity, regulatory limits, and desired top note profile

    Downstream process integration

    • Added during secondary blending of core aldehyde fractions; undergoes co-distillation or solvent stripping to ensure final mix volatility stability

    Final product types

    • Fine fragrance compositions, perfumed consumer products, home care fragrance oils, and personal care scent blends

    3. Agrochemical Intermediate Production

    Agrochemical synthesis facilities rely on 2-Ethoxybenzaldehyde as a chemical intermediate for producing oxygenated aromatic segments of herbicidal and fungicidal actives. Chemists combine it in acylation, alkylation, or heterocycle fusion reactions, capitalizing on the ethoxy group’s electron-donating effect for target selectivity. Traceability and residual monitoring are enforced to align with multi-country consumer safety standards in crop protection chemicals.

    Industry compliance standards

    • FAO/WHO Specifications for the Quality Control of Pesticides
    • OECD Good Laboratory Practice (GLP) guidelines
    • EPA 40 CFR Part 158 (Pesticide Data Requirements)
    • REACH substance registration (for intermediates in Europe)

    Typical usage ratio

    • Typically dosed at 3% to 7% by weight of total substrate in active ingredient precursor synthesis; tuned for precursor yield and downstream impurity minimization

    Downstream process integration

    • Fed into stirred reactor vessels during core ring functionalization stages, often alongside metal catalysts and controlled pH conditions

    Final product types

    • Herbicide intermediates, systemic fungicide actives, and specialty agrochemical additives

    4. Advanced Dye and Pigment Synthesis

    Colorant and pigment manufacturers employ this aromatic aldehyde in the creation of functionalized dye precursors, especially for azo and anthraquinone series molecules where selective alkylation and extended conjugation are critical. Formulators tune loading and reaction order based on the required color fastness and solubility profiles, while QA measures ensure residual reagent levels do not interfere with regulatory colorant approvals for consumer or industrial use.

    Industry compliance standards

    • EN 71-3 (Migration of certain elements in toy colorants)
    • OEKO-TEX Standard 100 for textile chemical safety
    • #1 AATCC TM61 (Colorfastness to laundering for dyes)
    • REACH registered substance requirements (for color chemicals in the EU)

    Typical usage ratio

    • Employed at 2.5% to 8% molar ratios relative to diazo or quinone core; ratios adjusted for desired chromophore strength and pigment loading in final dispersions

    Downstream process integration

    • Blended at the diazotization or oxidation step, with in-line filtration and solvent washes to control particle size and solubility

    Final product types

    • High-performance industrial pigments, textile dyes, printing ink dispersions, and functional masterbatch colorants

    5. Fine Chemical Synthesis for Heterocyclic Compounds

    Producers of specialty fine chemicals incorporate 2-Ethoxybenzaldehyde as a precursor or functionalization agent in multi-stage syntheses, especially for creating nitrogen- and oxygen-containing heterocyclic structures used in advanced material science and research. Route planning considers the aldehyde's reactivity towards specific nucleophilic partners and focuses on conversion rates, side-reaction minimization, and downstream reprocessing efficiency, meeting expectations for traceable impurity profiles applicable to specialty chemical manufacturing.

    Industry compliance standards

    • SOCMA ChemStewards® (Responsible Care Management System for fine chemicals)
    • ISO 9001:2015 (Quality Management Systems in chemical manufacturing)
    • Responsible Care Codes (Process safety and product stewardship)
    • GMP where compounds serve pharmaceutical or analytical uses

    Typical usage ratio

    • Utilized from 1 mmol up to 15% of mass balance, as dictated by the synthetic step, product polymorphism targets, and required purity thresholds

    Downstream process integration

    • Added during heterocycle-forming condensations, reductive coupling, or specific regioselective introductions, with batchwise monitoring for conversion and selectivity

    Final product types

    • Nitrogen- or oxygen-containing heterocycle building blocks, specialty research chemicals, and advanced intermediates for high-value material science
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    Certification & Compliance
    More Introduction

    Product Perspective: 2-Ethoxybenzaldehyde from a Manufacturer’s View

    Getting to the Heart of Our Chemical Craft: 2-Ethoxybenzaldehyde

    Among the many aromatic aldehydes turning the gears in the chemical sector, 2-Ethoxybenzaldehyde stands apart as a fine demonstration of how carefully designed chemistry meets real-world applications. For us, years spent refining synthetics mean every lot stands to the scrutiny of both lab and customer expectation. Genuine experience on the production line and in the synthesis lab shows you quickly which products truly go the distance. In the case of 2-Ethoxybenzaldehyde, our familiarity starts not with the finished bottle, but all the way from the sourcing of 2-ethoxybenzene and the aldehydation process, and into the multiple uses our clients find for its unique profile.

    Looking at the Details: Specification and Purity

    Strict quality is non-negotiable in our factory. Every kilogram of 2-Ethoxybenzaldehyde rolling off our line faces exacting standards suited to fine fragrance chemistry, pharmaceutical intermediates, and specialized materials. Purity levels above 98% are routine in our output. The typical product appears as a pale yellow to almost colorless liquid, with a molecular formula of C9H10O2 and a molar mass settling at 150.17 g/mol—verified batch by batch through both GC and HPLC. Practical details: its boiling point sits near 248°C, and its density hovers around 1.08 g/cm3. We keep water and acidic impurities in check, because these flaws cost customers time and yield down the line.

    How Our Process Influences Product Reliability

    Field experience in chemical manufacturing has pressed on us the impact even a minor slip in temperature or residence time can have. Over time, we invested in scalable stirred reactors, temperature automation, and upgraded distillation columns. Batch-to-batch repeatability isn’t about luck; it’s built on technical vigilance and constant analytical feedback. For 2-Ethoxybenzaldehyde specifically, the final distillation step makes or breaks product odor and color consistency. Our attention at this stage brings users less by-product interference—especially when their applications reach into areas like aroma chemicals where subtle impurities become glaring mistakes in a finished scent.

    The Place of 2-Ethoxybenzaldehyde in the Marketplace and Chemical Reactions

    Some folks ask what makes 2-Ethoxybenzaldehyde worthy of attention among so many benzaldehyde derivatives. It’s not simply another tick on a materials list. Functionalization at the ortho position with an ethoxy group brings heft in both reactivity and end-use versatility. This alteration from parent benzaldehyde amplifies its role as a flavor and fragrance building block. In the world of fine fragrance and ingredients, subtle shifts in substituent placement often mean the difference between a mundane base note and a prized component. Perfume chemists and formulators care about the warmth the ethoxy group imparts compared to, say, a plain benzaldehyde or a bulkier alkoxy alteration.

    On the pharma side, we encounter customer requests for intermediates in active pharmaceutical ingredient research. The ethoxy handle provides a useful anchor for further substitutions through ether cleavage or carbonyl functionalization. Custom reactions—think Grignard additions, reductive aminations, or even directed ortho-metalation—move forward more predictably with our high-purity starting material. Anyone who’s had a whole week’s development undone by trace metallics or oxidized byproducts in their aldehyde stock knows the cost behind the claims here.

    Our Take on Applications

    In more than two decades of directly supplying makers of aroma chemicals, our technical team has tracked a constellation of uses for this compound. Flavors, fragrances, and specialty organics lie at the nucleus. Its clean, pleasant, subtly nutty odor finds its greatest preference in high-end perfumery bases, especially where chemists seek mellow, less-harsh aldehydic structure. It isn’t just functional—the sensory properties matter to the noses in the lab and consumers down the line. We support formulators using this material in flavor work under applicable guidelines, but always stress a need for end-use analytical validation, as purity alone doesn’t confer regulatory clearance.

    One demand often echoed by our industrial users relates to solubility for blending into both polar and non-polar systems. The material dissolves efficiently in organic solvents yet keeps limited solubility in water—traits that simplify its integration into many matrices. Our users, especially in the coating and polymer sector, report that the ethoxy function brings useful chemical levers for post-integration modifications. Whether they pursue acetal derivatization or drop it straight into condensation reactions, working with predictable, contaminant-free 2-Ethoxybenzaldehyde trims lost time and makes for tighter material balance sheets.

    Comparing 2-Ethoxybenzaldehyde with Other Aromatic Aldehydes

    Years of comparison sampling tell us that not every aromatic aldehyde fills the same niche. Among alkoxybenzaldehydes, shorter groups like methoxy tilt volatility and reactivity, but often become too aggressive in odor. Overlong chains, say with butoxy groups, veer into waxy or fatty territory—less cared for by formulation chemists working toward clarity and moderate volatility. The ethoxy group balances these extremes. Customer feedback consistently indicates that 2-Ethoxybenzaldehyde checks the right boxes in olfactory intensity, tenacity, and chemical maneuverability.

    Plain benzaldehyde remains cheap and easy, but overuse leads to industrial monotony and isn’t tolerated in more nuanced compositions. Many applications—especially in perfumery—show better consumer reception when 2-Ethoxybenzaldehyde’s gentle warmth and reduced harshness come into play. Technically speaking, the substituent position matters: para-ethoxy and meta-ethoxy alternatives offer clear differences in both electronic effects and substitution chemistry. Yet, for the majority of fragrance and pharma builds tested in-house, ortho-positioned ethoxy gives superior results for subsequent modification or direct sensory performance.

    Long-Term Value: Handling, Shelf Life, and Storage Lessons Learned

    Lessons from years of storage of bulk and packaged material guide how we present recommendations. Despite its relative stability under recommended conditions (cool, dry, sealed vessels), even a well-made 2-Ethoxybenzaldehyde risks slow color drift if exposed to air or light. We’ve tackled these challenges by switching to nitrogen-blanketed drums in transit and suggesting brown glass or UV-resistant containers for smaller volumes. Our sustainability-minded partners now frequently request technical support on recycling or repurposing off-spec materials, building a broader stewardship ethos that runs parallel with chemical quality.

    On the production side, we avoid the temptation to over-process. Ultrafine filtration sometimes strips off nuance from what end-users want for fragrance foundations; our process engineers and lab analysts long ago set an upper limit on scrubbing aids and finishing throughput. Each tweak to purification finds us balancing material purity and desirable sensory traits—a trade-off most clear only to those who’ve both made and used the product, not just relabeled it for resale.

    Why User Feedback Shapes the Evolution of Our Product

    One unique edge of direct manufacturing is the chance to listen to real users and adapt. We regularly review notes from formulation teams, academic collaborators, and industrial chemists using this aldehyde as a core intermediate. Several years back, regular feedback about a faint off-odor in a few summer batches triggered a deep dive into our cooling jacket controls, and we’ve never repeated the issue. These iterative improvements rarely get noticed by label-readers, but heavy users—those who synthesize kilos rather than milligrams—see big gains in reliability, especially as scale increases.

    Our technical support staff remains engaged beyond the delivery note. Consultations evolve based on late-stage application troubleshooting, such as residual solvent concerns, crystallization tendencies at low temperature, or supplier substitutions in multi-site production chains. Scaling up a promising route from bench to pilot often unmasks volatility or storage tolerance issues otherwise invisible at lab scale, and our accumulated production and customer feedback data turns up in how we set process windows or batch-release criteria now.

    Supply Consistency and Transparency: Lessons from Downturns and Booms

    Anyone true to chemicals manufacturing remembers the times of market volatility—raw material shortages, logistical hiccups, or regulatory pivots. A few years back, disruptions in the supply of ethoxybenzene forced tighter stock allocations and upended delivery schedules industrywide. Our response? More diversified sourcing, raised safety stocks internally, and stepped up in-house analytics; these measures have paid off across market cycles. Our real strength comes from production lines that can flex output but refuse to cut corners. We compete on methodical tracking, from raw material arrival through to finished material sign-off, not by swapping out sources or shortcuts that would undermine end-user trust.

    Research, Innovation, and the Future of Aromatic Aldehydes

    Manufacturers like us who spend decades surrounded by aromatic intermediates see demand curves move, but we see even more dramatic shifts in technical requirements. Research into green chemistry and sustainable feedstocks nudges us out of comfort zones. Current projects in our development suite include new catalysts to make the aldehydation stage less resource-intensive and waste-reducing distillation techniques. Our process engineers embrace the challenge, betting on incremental improvements that float downstream as bottom-line savings and a smaller environmental stamp. Close partnerships with academic labs shape prototype runs, allowing the next generation of 2-Ethoxybenzaldehyde to show better carbon efficiency and reduced solvent use.

    The market’s push for low-tox and biobased derivatives emphasizes the need for ongoing reinvention. Customers increasingly want proof—LC/MS spectra, traceability, and lifecycle assessments—instead of just certificates or audit statements. We’ve taken to opening up more of our analytical protocols and tracking supply chain milestones, even as our lab staff stays quiet about proprietary tweaks learned from hard-won process experience. For some, this seems excessive; for us, it’s simply the cost of credibility and a sign of commitment to long-term quality.

    Summary: Experience Beyond the Label

    Reflecting on the path from raw material to packaged product, 2-Ethoxybenzaldehyde means more than a chemical formula on an invoice. It shows the intersection of thoughtful process management, technical rigor, detailed sensory and analytical work, and responsive customer interaction. Years of hands-on production and direct client engagement remind us that every barrel or drum pulled from our warehouse carries both our reputation and a shared responsibility to the industries downstream. The chemical market sees lots of resellers and brokers putting their mark on commoditized products, but only close-to-the-source manufacturing can deliver the trusted performance and honest feedback loop serious users count on.

    Choosing the right supplier for any aromatic aldehyde means more than checking off a few purity boxes. It demands honest history in production, willingness to help resolve unexpected application snags, and consistent improvements both in chemical and service. From our vantage point, that’s what keeps us motivated to return to the line, batch after batch—making sure our 2-Ethoxybenzaldehyde stands up to both analytical scrutiny and the tougher tests of real-world use.