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2-Cyclohexylphenol

    • Product Name 2-Cyclohexylphenol
    • Alias 2-Cyclohexylphenol
    • Einecs '245-009-3'
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    833111

    Chemical Name 2-Cyclohexylphenol
    Cas Number 1655-77-0
    Molecular Formula C12H16O
    Molecular Weight 176.26 g/mol
    Appearance White to off-white solid
    Melting Point 61-64°C
    Boiling Point 305-307°C
    Density 1.067 g/cm³
    Solubility In Water Insoluble
    Flash Point 143°C
    Refractive Index 1.570
    Purity Typically ≥98%
    Smiles C1CCC(CC1)C2=CC=CC=C2O

    As an accredited 2-Cyclohexylphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of 2-Cyclohexylphenol, sealed with a screw cap and labeled with safety and identification information.
    Shipping 2-Cyclohexylphenol is shipped in sealed, chemical-resistant containers, typically with proper labeling and hazard identification. It should be transported according to local, national, and international regulations for hazardous materials, protected from moisture, direct sunlight, and incompatible substances. Ensure compliance with safety protocols and provide appropriate documentation during shipping and handling.
    Storage 2-Cyclohexylphenol should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and store it away from incompatible materials such as strong oxidizers and acids. Use appropriate, labeled chemical-resistant containers. Personal protective equipment should be used when handling, and spills or leaks should be cleaned promptly using proper procedures.
    Application of 2-Cyclohexylphenol

    Applications of 2-Cyclohexylphenol in Industrial Manufacturing

    2-Cyclohexylphenol serves as a key intermediate in several specialized chemical production sectors. Our on-site synthesis and rigorous quality control ensure consistent supply for downstream manufacturers requiring high-purity grade materials. Below are major industrial uses and specific integration details for this compound.

    1. Antioxidant Additives for Lubricant Manufacturing

    Formulators in the lubricant industry employ 2-Cyclohexylphenol to synthesize phenolic antioxidants. These components prevent oxidative degradation in mineral and synthetic base stocks. The compound enters antioxidant blends where its cyclohexyl group enhances thermal stability and oil solubility under elevated operating temperatures, extending lubricant life in heavy-duty engines and industrial gear systems. Strict batch testing verifies compatibility with engine oil formulations and hydraulic fluid standards.

    Industry compliance standards

    • ASTM D6571: Standard Test Methods for Antioxidant Content in Lubricant Oils
    • API (American Petroleum Institute) lubricant performance specs: SN, CK-4, SP
    • European REACH (EC 1907/2006) substance registration and safety requirements

    Typical usage ratio

    • Antioxidant concentration: 0.3% to 1.2% by weight in finished oil formulation; dosage adjusted based on base oil saturation and blending method

    Downstream process integration

    • Added during blending of antioxidant concentrate, dissolved at 60-90°C before inclusion in finished lube blends
    • Quality control by HPLC and colorimetric tests prior to bulk tank storage

    Final product types

    • Automotive engine oils (PCMO, HDEO)
    • Turbine and compressor oils
    • Industrial gear oils
    • Hydraulic fluids

    2. Intermediate in Agricultural Fungicide Synthesis

    Agrochemical manufacturers utilize 2-Cyclohexylphenol as a starting material for key phenolic fungicide active ingredients, such as propiconazole derivatives. The material reacts via electrophilic substitution, enabling precise substitution on the aromatic ring. Close monitoring of raw material identity and purity prevents residual phenols and byproducts in final actives, aligning with agrochemical regulatory demands for food safety and environmental toxicity.

    Industry compliance standards

    • FAO/WHO specifications for pesticide active ingredients
    • OECD Good Laboratory Practice (GLP)
    • US EPA 40 CFR Part 158 data requirements for pesticide registration

    Typical usage ratio

    • Used at 1.0 to 2.2 molar equivalents per mole of active ingredient, potency and yield tracked by GC-MS for each process lot

    Downstream process integration

    • Engages in alkylation or halogenation steps in multiphase reactor trains
    • Undergoes high-shear mixing for complete solubilization before coupling reactions

    Final product types

    • Azole fungicide technical concentrates
    • Suspension concentrate formulations
    • Emulsifiable concentrates used in row crop protection

    3. Monomer Modifier in Specialty Polymeric Resins

    Producers of high-end phenolic or polycarbonate resin systems introduce 2-Cyclohexylphenol as a monomeric modifier to adjust resin melt-flow and flexibility. The cycloaliphatic substituent reduces chain rigidity, enabling better impact resistance in demanding applications like electrical laminates and molded automotive components. Control over substitution ratio ensures consistent polymer physical properties and facilitates downstream molding and curing cycles.

    Industry compliance standards

    • ISO 9001:2015 certified production and QC
    • UL 94 Flammability Testing for Electrical Resins
    • EU RoHS Directive (2011/65/EU) for electronics resin applications

    Typical usage ratio

    • Modifier addition: 2% to 10% by weight of the primary resin monomer feed; adjusted per target flex modulus and glass transition temperature (Tg)

    Downstream process integration

    • Charged with other phenol-type monomers at pre-polymerization condensation stage
    • Melt or solution polymerization at 110–160°C under nitrogen sweep

    Final product types

    • Printed circuit board (PCB) resins
    • High-impact molded housings
    • Heat-resistant industrial adhesives
    • Specialty composites for transport electrification

    4. Synthesis of UV Stabilizer Intermediates

    Manufacturers in the polymer additives sector utilize 2-Cyclohexylphenol to build intermediates for hindered phenolic UV stabilizers. These intermediates help protect sensitive polymers such as ABS, polypropylene, and polyurethane from photodegradation. The use of cyclohexyl-substituted phenols in synthesis permits tailored light absorption profiles with low volatility, critical for long-life outdoor plastic applications.

    Industry compliance standards

    • FDA 21 CFR 178.2010 for plastic additives in food contact materials
    • EN 71-3:2019 (Safety of toys — migration of certain elements)
    • ISO 4892-2: Accelerated UV aging test protocols for plastics

    Typical usage ratio

    • Active intermediates: 0.1% to 0.8% in finished UV stabilizer masterbatch, adjusted based on matrix polymer reactivity and exposure load

    Downstream process integration

    • Synthesized into triazine or benzotriazole structures via controlled condensation reactions
    • Final additive blended directly into polymer melt or applied as surface treatment during extrusion

    Final product types

    • Polyolefin UV-stabilizer pellets
    • Weather-resistant engineering plastics
    • Outdoor furniture and enclosure parts
    • Plastic greenhouse films

    5. Precursors for Pharmaceutical Fine Chemicals

    The pharmaceutical fine chemicals industry relies on 2-Cyclohexylphenol for targeted synthesis routes in non-steroidal drug intermediates. The aromatic-alicyclic balance enables regioselective functional group transformation, crucial in custom syntheses for antihypertensive and neuroactive candidate molecules. Our GMP-audited production supports reliable batch-to-batch supply, and careful chromatographic analysis ensures absence of regulated impurities, fulfilling regulatory and safety filing requirements.

    Industry compliance standards

    • ICH Q7: GMP for Active Pharmaceutical Ingredients
    • USP/NF and Ph. Eur. monographs (as applicable to derivatives)
    • FDA 21 CFR Part 210/211: Drug substance and intermediate control

    Typical usage ratio

    • Precursor charged at 0.8-1.4 equivalents per final API reaction, ratio refined per process validation batch

    Downstream process integration

    • Included in early-stage aromatic substitution or reduction processes
    • Monitored for conversion and trace phenol removal at intermediate isolation

    Final product types

    • Intermediates for cardiovascular drug actives
    • Precursors for CNS agent synthesis
    • Custom semi-synthetic molecules for CRO and CDMO markets
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    Certification & Compliance
    More Introduction

    Real-World Advantages of 2-Cyclohexylphenol: Insights from Chemical Manufacturing

    Experience Earned in Purpose-Driven Chemistry

    Every chemist and plant manager knows their raw materials shape the fate of every reaction. Through decades behind reactors and powder mixers, we have learned that 2-Cyclohexylphenol stands out for its versatility and reliability in applications demanding a strong, non-polar aromatic base. We have had more requests for this molecule each year as development labs seek innovation and scalable solutions. As a manufacturer, our insight grows not from market trend charts, but from noisy shop floors and feedback calls from firms looking to do more with less. This material allows formulators and downstream processors to open doors otherwise blocked by limits in classical phenolic compounds.

    What Sets 2-Cyclohexylphenol Apart

    Our team routinely refines batches to ensure a GC purity above 99 percent, eliminating common trace contamination from less selective methods. By bringing in high-spec cyclohexyl reagents directly from trusted upstream partners, we achieve a finished product with consistent melting behavior and transparent supply chain documentation. In practice, the cyclohexyl ring delivers both steric hindrance and hydrophobicity, which translates into properties not possible from parent phenol or its simple alkyl derivatives.

    Other phenolic intermediates often struggle with volatility or produce unwanted byproducts under oxidative or condensing conditions. 2-Cyclohexylphenol’s ring system gives formulations both chemical resistance and a tunable activation barrier. We’ve seen clients in agrochemical synthesis gain higher selectivity when using our product, avoiding diglycol impurities or over-alkylated waste found with less tailored phenols. That advantage is decisive in scale-up, where every increment of selectivity can tip the balance between a viable project and a non-starter.

    On the Reactor Floor: Model, Specifications, and Day-to-Day Handling

    Most plants request our standard pharma/intermediate grade, produced as a white to faintly beige crystalline solid. By controlling crystallization kinetics and solvent streams, we consistently achieve a melting point in the typical 51–53°C range, which has made downstream weighing and feeding operations predictable and efficient. Technical sheets report purity by HPLC and headspace GC, but real trust comes from repeatability: the same batch profile across months or years, enabling process engineers to design protocols around known parameters instead of guessing at batch-to-batch drift.

    Our packaging lines run both 25 kg drums and custom tote bins, closed under nitrogen. Staff document every transfer, starting from raw feedstocks, through reaction, workup, and drying. This transparency pays off. When end-users report on fouling or material carryover in blending, we respond with full batch histories. This level of control has cut the number of out-of-spec shipments to near zero.

    How Clients Deploy 2-Cyclohexylphenol

    Throughout our history, the clientele buying 2-Cyclohexylphenol tends to split between fine chemical synthesis groups and specialty polymer makers. One polymer R&D head told us, “With cyclohexyl substitution, we can tune the resin backbone for temperature resistance without losing too much flexibility.” Epoxy formulators find 2-Cyclohexylphenol’s aromatic base enables coupling or chain-terminating reactions that bring both backbone rigidity and greater water repellency. This provides coatings that push well beyond the standard thermal or solvent resistance found in products based on cresols or xylenols.

    On the agrochemical side, process chemists rely on this material as a building block for specific herbicidal and plant growth regulator scaffolds. In some cases, this molecule serves as a privileged intermediate: introducing the cyclohexyl group early in synthesis offers both functional group tolerance and fewer rearrangement steps later. We have handled custom requests where users required tailored particle sizing or ultra-low moisture levels, and by having control over every kiloliter and centrifuge, delivered accordingly—often within days of request.

    Our many years preparing this molecule in multiple grades means we’ve seen it all, from use in colorants that demand high UV stability, to personal care sector trials where skin compatibility and extractables receive intense scrutiny. No matter the application niche, direct technical dialogue with our customers leads to practical, lasting process improvements.

    Down-to-Earth Differences from Other Phenolic Intermediates

    Behind every solvent drum and powder sack, differences come down to how materials behave in actual process lines. Take basic phenol: its reactivity is robust, but it evaporates and oxidizes fast, leading to handling hazards and extra ventilation. 4-tert-butylphenol brings more sterics but at the cost of lower thermal stability and distinctive odor, restricting its use in certain consumer applications.

    Our in-line sampling shows that 2-Cyclohexylphenol, thanks to its non-linear, saturated cyclohexane ring, brings a balance: it is much less prone to airborne losses and gives a lower volatility load on exhaust scrubbers. We have engineered closed transfer systems directly for this grade, protecting both product quality and worker safety. No need for extra backend scrubbing. By minimizing worker exposure, plant managers gain peace of mind and process safety incidents drop below what we’ve tracked for more volatile phenolic types.

    Compared with methylphenols, cyclohexyl substitution tilts the molecule’s solubility profile towards organic media, yielding better compatibility with non-polar and amphiphilic additives. That means easier blending with resin precursors or solvent systems in paints. One coatings manufacturer reported reduced separation after milling by simply switching to our product, which helped them cut defect rates and warranty returns in finished gloss coatings.

    Making Reliable Chemistry Possible

    We have invested in upstream process optimization: continuous flow reactors, improved distillation, solvent purification, and advanced filtrations let us push impurities down into the parts-per-million range. To our lab staff, this translates into freedom—from time lost cleaning up sticky or unstable residues, from lost batches caused by wayward byproducts, from second-guessing the certificate of analysis before every run.

    We do not stand still on process safety, either. Installations run dust extraction and ventilation specifically tailored for this product’s particle size and melting point, keeping operator exposure well within recommended thresholds. Long-term, this builds trust with occupational health stewards and sets a standard that outlasts lean years or high-order booms.

    Reducing Downtime and Improving Cost-Efficiency

    Every hour in shutdown for maintenance or cleaning between batches costs money and time—and frustrates chemists eager to move projects forward. More predictable crystallinity and less tendency to cake in feeders result in faster line startup and fewer unscheduled stoppages. During our own internal trials, we reduced auger blockages by nearly 40 percent after implementing tighter temperature controls during final drying.

    Because the molecular structure holds up under moderate heat, we’ve seen partners raise their process temperature setpoints in continuous reactors by 15 to 30°C, achieving faster cycle times and higher space-time yields. In legacy lines, that extra efficiency translates into more kilos shipped per week, without the capital investments needed to overhaul their entire plant.

    Supporting Green Chemistry and Waste Reduction

    Years ago, one of our large-scale clients faced rising pressure to cut volatile organic compound (VOC) emissions during large batch ops. Classic phenols churned out too much airborne waste. By switching to 2-Cyclohexylphenol, emissions dropped within the first two months of conversion. Their audits now pass on the first attempt, and local regulators use their plant as a model for applying best practices. That came down to material science—choosing a compound with intrinsically lower vapor pressure and a more benign environmental profile.

    From our own emissions records, the shift to this molecule lopped several metric tons per year off our own permit filings for hazardous air pollutants. In leaner years, that means lower compliance costs and fewer interruptions from spot checks. In robust years, it means more throughput, more opportunity to invest in sustainable projects, and a stronger legacy for the next generation of chemists on our team.

    Direct Technical Support and Open Feedback Loops

    We run plant tours and open labs where processors and R&D specialists come to see real batches, run small-scale demos, and review our process data. That culture of transparency—answering tough questions directly and catching issues before they hit production—is the only way to keep pace. Recently, a polymer formulator flagged sporadic gelation using legacy drums during a high-heat run. Our QC lead, armed with production logs and vendor solvent profiles, traced the root to condensation at the rail terminal—a logistics wrinkle, not a synthesis fault. The partnership solved it within a shift and helped us rewrite unloading guidelines, improving quality not only for that client but for everyone else along the logistics chain.

    Such hands-on feedback closes the loop and keeps us focused. It fuels both incremental tweaks in daily practice and deeper R&D efforts to expand the range of what 2-Cyclohexylphenol can deliver. It’s one thing to read data sheets, it’s quite another to watch firsthand how a nuanced property—like melting curve or fine dust fraction—affects a hundred-meter reactor train. We value not just the science, but the ongoing collaboration with every plant engineer, resin chemist, and packaging manager at the receiving end.

    Continuous Process Improvement

    Years of run logs have taught us something simple: small upstream improvements ripple through supply chains and lab benches. Last year, a minor adjustment to our hydrogenation times tightened the product’s chromaticity, allowing partners in the pigment industry to shift from multiple filtrations to a single step. Those same tweaks prevented build-up on the vessel’s baffles, which saved us a monthly chemical cleanout and thousands in labor.

    It’s not glamorous work, but it adds up. Wastage goes down, schedules run truer, and end users report fewer hiccups in their own production. The best advancements rarely come from a flash of genius—they come from honest data review and open communication between everyone in the value chain.

    No Substitute for Real-World Testing and Support

    As much as we invest in heavy equipment and analytical tools, nothing beats on-site feedback from our partners. Whether a researcher pushing the boundaries of polymer chemistry or an engineer scaling a new herbicide payload, seeing how 2-Cyclohexylphenol responds in their real processes keeps us sharp. Every challenge—clumping in pneumatic transfers, color drift, or material sticking to grinders—becomes an R&D prompt. Over the last five years, we have recalibrated particle sizing, added dedicated batch heaters, and fine-tuned packing density thanks to the lessons learned from customer shop floors, not just our own.

    Working closely with those who test, mix, and react our product ensures we spot pitfalls far sooner than if we had simply relied on external reports or academic forecasts. This approach means fewer disruptions and a closer understanding of what our material delivers in lived experience.

    Investing in Tomorrow’s Applications

    Applied chemistry keeps moving. Current discussions with industry groups focus on using 2-Cyclohexylphenol as a stepping stone towards smart multifunctional materials—surfactants with custom-tailored hydrophobic/hydrophilic balances, crosslinked thermoplastics with next-generation toughness, or even biodegradable intermediates. Researchers are pushing our molecule into advanced catalysis work and pharmaceutical synthesis, where its steric profile acts as a gatekeeper for specific transformations.

    We have seen this product’s inherent resistance to oxidation and hydrolysis map closely to a new generation of performance coatings that withstand harsh outdoor or marine environments. Such advancements ride on the backbone of consistent, scalable chemistry—qualities we have spent years refining batch after batch. Every time we invest in purification or process controls, it is to help unlock that next leap, creating new business for our partners and a greater creative space for R&D teams.

    Closing Thoughts from the Factory Lines

    Our core message remains the same: 2-Cyclohexylphenol offers not just a chemical building block, but a suite of practical advantages shaped through years of hands-on manufacturing. Each improvement—tighter purity specs, safer handling, open channels for technical feedback—drives better, cleaner, and more economical operation for producers large and small.

    Much more than a data sheet, this material embodies a philosophy: if you keep the feedback lines open from reactor to lab bench to loading dock, the chemistry and the people using it move forward together. That’s the journey we share with every partner, batch by batch, year after year.