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2-Cyclohexyl-5-Methylphenol

    • Product Name 2-Cyclohexyl-5-Methylphenol
    • Alias Carvacrol
    • Einecs 240-622-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    217841

    Chemical Name 2-Cyclohexyl-5-Methylphenol
    Molecular Formula C13H18O
    Cas Number 5181-02-6
    Appearance White to off-white solid
    Melting Point 71-73°C
    Boiling Point 314°C
    Density 1.03 g/cm³
    Solubility In Water Insoluble
    Structure Cyclohexyl group at position 2, methyl group at position 5 on phenol ring
    Synonyms 2-Cyclohexyl-5-methylphenol; PCMX
    Smiles CC1=CC=C(C=C1O)C2CCCCC2
    Flash Point 150°C
    Refractive Index 1.550 (estimated)
    Usage Antimicrobial agent

    As an accredited 2-Cyclohexyl-5-Methylphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 g, sealed with screw cap, labeled with chemical name, hazard symbols, batch number, and supplier details.
    Shipping 2-Cyclohexyl-5-methylphenol should be shipped in tightly sealed containers, protected from moisture and direct sunlight. The shipment must comply with local and international regulations for chemicals. Proper labeling, documentation, and handling precautions are required to ensure safety during transit. Avoid extreme temperatures and keep away from incompatible substances.
    Storage Store **2-Cyclohexyl-5-Methylphenol** in a tightly closed container, in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Keep the storage area free from moisture and ignition sources. Ensure containers are clearly labeled and handled using appropriate personal protective equipment. Follow all relevant safety and chemical storage regulations.
    Application of 2-Cyclohexyl-5-Methylphenol

    Applications of 2-Cyclohexyl-5-Methylphenol in Industrial Manufacturing

    2-Cyclohexyl-5-Methylphenol serves as a key specialty intermediate in several established industrial sectors. As the manufacturer, we supply this material to customers with advanced technical requirements relating to antimicrobial formulations, personal care preservatives, high-performance polymers, veterinary pharmaceutical synthesis, and specialty surface coatings. Below are major downstream application scenarios, each representing a concentrated real-world use with explicit industry practices.

    1. Antimicrobial Preservatives for Industrial Cleaning Formulations

    Industrial cleaning product manufacturers rely on our material as a highly effective phenolic biocide to inhibit a broad spectrum of bacteria and fungi in aqueous and non-aqueous formulations. Its cyclohexyl and methyl-substituted phenol structure offers strong membrane-disruptive activity, supporting long-term preservation in high-contamination environments, even at low concentrations. Downstream producers incorporate the product directly during final blending of microbially sensitive formulations, maintaining compliance with leading chemical regulatory regimes.

    Industry compliance standards

    • U.S. EPA 40 CFR 180.940 (Tolerance Exemptions for Antimicrobial Substances for Food-Contact Surface Sanitizers)
    • EU Biocidal Products Regulation (BPR, EU 528/2012)
    • China GB 38508-2020 (Use of Antimicrobial Agents in Industrial Products)
    • REACH Annex XVII substance use restrictions

    Typical usage ratio

    • 0.05%–0.30% w/w in industrial hard surface cleaners, disinfectants, and process water treatments; dosage adjusted according to microbial challenge testing results and intended in-use dilution factors.

    Downstream process integration

    • Added post-emulsification or after base solution neutralization; avoids high shear or thermal degradation by integrating during cooled batch stages before final bottling or packaging.

    Final product types

    • Industrial disinfectants (hospital, food plant, janitorial)
    • Recirculating cooling water biocides
    • Sanitizing wipes and sprays
    • Heavy-duty degreasers

    2. Personal Care Preservatives in Cosmetic and Toiletry Manufacturing

    Personal care industry clients utilize this molecule as an active antimicrobial preservative in sophisticated leave-on and rinse-off formulations. Its specific activity against Gram-positive organisms makes it attractive for deodorant, shampoo, and hand wash development, particularly where paraben- or formaldehyde-free declarations are critical. Compound is dissolved in the oil or solubilizer phase and incorporated into the bulk mix at sub-0.5% levels to avoid regulatory ingredient cutoffs and maintain sensory profile parameters.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009, Annex V for preservatives
    • U.S. FDA OTC Monograph for Skin Protectants (21 CFR Parts 310, 347)
    • China Cosmetic Safety Technical Specification (2015, updated 2022)
    • ISO 11930:2020 (Microbial Challenge Testing)

    Typical usage ratio

    • 0.10%–0.35% w/w based on total batch weight; level varies depending on the presence of surfactant, pH, and preservative efficacy test results.

    Downstream process integration

    • Integrated into the main vessel after cooling emulsions to below 45°C, or pre-dispersed in glycols for clear gel and shampoo types to assure even distribution and prevent phase separation.

    Final product types

    • Roll-on and stick deodorants
    • Liquid hand soaps
    • Shampoos and conditioners
    • Facial cleansers

    3. Synthesis Building Block in Veterinary Pharmaceuticals

    Veterinary pharmaceutical manufacturers source this phenolic intermediate as a crucial building block for non-steroidal anti-inflammatory drugs (NSAIDs) and antimicrobial veterinary actives. Its molecular framework supports regioselective reactions during heterocyclic synthesis and esterification steps. Downstream integration most frequently occurs during the early-stage active pharmaceutical ingredient (API) manufacturing, where strict impurity profile controls are mandated by regulatory dossiers.

    Industry compliance standards

    • US FDA 21 CFR 514 (Animal Drug Applications), ICH Q7A (GMP for APIs)
    • European Pharmacopoeia (Ph. Eur.) monographs for veterinary actives
    • Chinese Veterinary Pharmacopoeia (CVP 2020 Edition)
    • VICH GL10 (Impurities in New Veterinary Drug Substances)

    Typical usage ratio

    • Varies by synthetic route; typically 0.8–1.2 equivalents relative to target heterocycle backbone for each batch during API synthesis.

    Downstream process integration

    • Reacted during the early condensation or alkylation stage of API manufacturing; subjected to further purification and chemical transformation prior to formulation into final dosage form.

    Final product types

    • Veterinary oral and parenteral NSAID formulations
    • Antimicrobial feed additives
    • Topical veterinary ointments
    • Animal health injections

    4. High-Performance Polymer and Resin Modification

    Specialty polymer producers leverage 2-Cyclohexyl-5-Methylphenol as a reactive modifier, imparting both enhanced hydrolytic stability and antimicrobial attributes to thermoset and thermoplastic resins. Its inclusion as a co-monomer or chain stopper is critical in industrial polymerization for engineered materials used in medical device casings and other high-touch surfaces. Such modifications occur during controlled addition in the in situ polymer chain propagation step.

    Industry compliance standards

    • USP Class VI Plastics (for medical applications)
    • ISO 10993-1 (Biological Evaluation for Medical Devices)
    • FDA 21 CFR 177 (Indirect Food Additives: Polymers)
    • REACH SVHC and Compliance Dossier Review

    Typical usage ratio

    • 0.2%–1.2% by weight related to total polymer resin, depending on required antimicrobial activity or target molecular weight control in the finished matrix.

    Downstream process integration

    • Incorporated at the monomer feed or post-polymerization blending stage, typically in jacketed reactors under inert gas protection to prevent premature oxidation or crosslinking.

    Final product types

    • Medical device housings and surgical tool handles
    • Hygienic wall panels and public facility surfaces
    • Food processing conveyor belt parts
    • Anti-bacterial appliance coatings

    5. Specialty Surface Coatings for Hygiene and Protection

    Manufacturers of specialty industrial and institutional coatings formulate with this active to deliver durable, non-leaching antimicrobial properties. Applied primarily in paint and varnish systems designed for hospitals, laboratories, and high-traffic public spaces, the compound integrates into the pigment dispersion or final compounding step to assure homogenous distribution and maintained surface activity throughout the lifespan of the coating. Appropriate usage aligns with rigorous product labeling and efficacy substantiation requirements.

    Industry compliance standards

    • US EPA Antimicrobial Performance Test Guideline OCSPP 810.2200
    • EN 13697 (Surface Activity for Chemical Disinfectants and Antiseptics)
    • ISO 22196:2011 (Measurement of Antibacterial Activity on Plastics and Other Non-porous Surfaces)
    • China HJ/T 201-2015 (Technical Requirements for Antimicrobial Coatings)

    Typical usage ratio

    • 0.05%–0.25% in acrylic, polyurethane, or epoxy coating bases; precise metric determined by substrate porosity, intended use case, and accelerated ageing test results.

    Downstream process integration

    • Dispersed during resin blending or pigment mill-out to assure fine-scale integration; final viscosity checked before packaging to avoid settling of active component.

    Final product types

    • Antimicrobial wall paints (healthcare, transit facilities)
    • Epoxy floor coatings for food and beverage plants
    • Protective surface sealants for touch panels
    • Clear antimicrobial varnishes for public utilities
    Free Quote

    Competitive 2-Cyclohexyl-5-Methylphenol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Introducing 2-Cyclohexyl-5-Methylphenol: Specialty Phenolic Innovation from the Factory Floor

    Real Chemical Value, Direct from the Manufacturer

    Experience shapes how we approach chemical solutions. After decades of hands-on manufacturing, we have learned plenty about the small details that go into producing specialty phenol derivatives. 2-Cyclohexyl-5-Methylphenol stands out in our catalog for several reasons; it never falls into the generic range of phenolics most traders try to push. True utility in chemical manufacturing comes from understanding not just the structure, but the behavior in real-world applications.

    Our Perspective on Producing 2-Cyclohexyl-5-Methylphenol

    We handle the raw materials and run the reactors ourselves. That means each batch of 2-Cyclohexyl-5-Methylphenol hits the shelf after real-time checks, not just a rubber-stamp certificate. In the plant, we see how cyclohexyl substitution brings new dimensions to the table. The methyl group adds subtle differences in terms of solubility and chemical reactivity. Our team knows these tweaks can make a world of difference in product development labs. Judged on appearance, you’ll see a clear or slightly off-white crystalline solid. You get a reliable melting point and consistent particle size, factors we check throughout the process.

    Why 2-Cyclohexyl-5-Methylphenol Catches the Interest of Innovators

    Over the years, new product developers in coatings, polymers, and specialty biocides keep coming back to this compound for a reason. The cyclohexyl group brings steric bulk, which means the molecule can withstand harsher chemical environments without rapid degradation. Companies creating advanced antimicrobial formulations rely on this stability. On the manufacturing line, we’ve tested and compared it against common alkylphenols. Most break down faster under heat and sunlight; cyclohexyl-methyl variants like this show far greater long-term consistency, reducing the risk of off-odors or color drift in finished products.

    Specifications Backed by Hands-On Practice

    Lab results matter, but so does experience. We measure melting point, purity, water content, and residual solvents in our own facility before we ship. Typical purity exceeds 99%. Our solvents and intermediates team pays careful attention to crystallization, since even minor impurities can throw off downstream reactions. You get a phenolic odor with moderate volatility — nothing overpowering, and easily handled in standard ventilated environments. We’ve found that the cyclohexyl group provides better processability in high-polymer environments, with less unexpected gellation compared to simple cresols or xylenols.

    How Real-World Users Benefit from Our Approach

    We have watched formulators experiment with dozens of phenolic compounds. 2-Cyclohexyl-5-Methylphenol works especially well as a building block for high-performance resins and stabilizers. Some clients use it directly as an antioxidant, seeking that balance between cost and resistance to oxidation. Others incorporate it as a modifier in epoxy systems, reporting smoother curing curves and fewer bubble-formation problems. Pharmaceutical developers sometimes explore its broader analogues, as similar reagents offer selective reactivity for specialized ligands or esters.

    Understanding the Core Differences: Beyond Traditional Alkylphenols

    Old-school phenols like para-cresol or 2,6-xylenol have their place. We produced them for years and still run loads for bulk applications. In high-value sectors, they often fall short. 2-Cyclohexyl-5-Methylphenol fills the gap where greater steric hindrance and slightly higher molecular weight are critical. Unsubstituted methylphenols usually react too quickly, or offer poor compatibility with modern polymer blends. Cyclohexyl substitution allows tighter control of reaction rates, thermal stability, and melt behavior. This isn’t marketing spin — we’ve seen it ourselves while troubleshooting failures for customers who struggled with older phenol grades.

    Reliability from Batch to Batch: Our Factory Practice

    Consistency can make or break an industrial process. We control our process right down to temperature ramping and solvent removal. Each reactor run provides traceable lot records, checked by our shift chemists who know what variance in odor or color means on the next stage. Our quality team maintains digital and hands-on logs to spot trends long before a batch goes out. If one stage of raw material handling veers outside target spec, we isolate and rework it before shipment. Stainless steel reactors and filtrations with food-grade seals keep contamination down. These details get missed in secondary markets but matter every single day on production floors.

    Real-World Challenges: What We’ve Learned Supplying Niche Chemicals

    Most distributors never see long-term user complaints — but manufacturers do. Customers come to us with thermal stability challenges for finished adhesives exposed to year-round temperature swings. We’ve documented how 2-Cyclohexyl-5-Methylphenol’s balance of rigidity and moderate flexibility translates into lower failure rates after months of exposure. Handling spills, optimizing for large-scale mixers, and scaling up pilot batches all show what a difference raw material choice makes. Problems with off-spec material don’t stay hidden in bulk shipping either — they surface at the user’s end with gellation or crystallization issues that can trace back to a single missed control point at our plant.

    Supporting Data and Real Feedback

    We prefer straightforward feedback over layers of middlemen. Years of experience with this compound allow us to supply technical support informed by both production analytics and customer experience. As new markets like high-durability construction polymers and outdoor-use plastics expand, we keep seeing the specific advantage of cyclohexyl-modified phenols in physical and chemical testing. Manufacturing is real work — it brings real data, not just sales promises. When epoxies or adhesives based on this molecule outperform common blends under stress, our clients share those results with us. We use this information to fine-tune tank cleaning, drying routines, and filtration during subsequent runs.

    Limitations and Practical Considerations

    We admit that specialty chemicals bring new handling considerations. 2-Cyclohexyl-5-Methylphenol changes the flow viscosity of resin blends. Our operators monitor filtration speed in order to optimize downstream production for coatings and sealants customers. The crystalline form travels well, but in extremely humid conditions, we recommend additional packaging layers. Over time, we found certain binder packages in paints react more slowly with cyclohexyl-modified phenols, which helps users extend pot life but can require extra care in curing schedules. These are notes we track and share with formulators who need granular advice on adapting their processes.

    Avoiding Common Pitfalls: Practical Advice from the Plant

    Early on, we faced our share of headaches trying to fit this innovation into aging equipment. Pumps set for lower-viscosity fluids needed careful adjustment. Initial scale-ups found that the thicker solution sometimes left residues in bends and fittings; we switched up agitation protocols and extended rinse times. Plant maintenance staff learned quickly to check for traces of cyclohexyl residues when routine cleaning didn’t fully clear the lines. Most users adapt within a couple of batches — our technical team checks in directly with industrial users to help dial in these parameters.

    Comparing 2-Cyclohexyl-5-Methylphenol to Simpler Alternatives

    Jumping from low-cost alkylphenols to a more sophisticated structure often brings questions about value. Seeing the proof firsthand, the added stability and controlled reactivity pay off in higher yields and reduced rework. Resin plants benefit from lower yellowing risks. Polymer clients have fewer issues with batch-to-batch color drift, especially under UV exposure. Bulk methylphenols rarely match up in these categories. In antimicrobial applications, cyclohexyl-methyl phenols don’t degrade as quickly, resisting breakdown even in aggressive formulations packed with strong acids or bleach. This saves time and cost in quality complaints.

    Usage Scenarios We’ve Supported

    Leading resin formulators routinely call on us to provide larger particle-size lots, supporting bulk production of weather-resistant plastics. Labs working on electrical insulators use fine-graded batches, noting how the compound’s stability translates to greater dielectric performance. For chemical intermediates, 2-Cyclohexyl-5-Methylphenol steps in where substituted cresols become too reactive or volatize at inconvenient temperatures. Clients have explored it in biocidal polymers and wood preservatives — anywhere durability and slow degradation are non-negotiable. We’ve solved labeling concerns by working with labs on clearer documentation of molecular structure for compliance reviews.

    Practical Knowledge on Storage and Handling

    Our warehouses use sealed containers resistant to light and humidity, since cyclohexyl-methyl phenols retain best stability in these conditions. We handle large drums using closed transfer, which reduces time in the open air. To avoid cross-contamination with halogenated solvents, we dedicate filtration trains and packaging lines. On user sites, best practice involves climate-controlled storage, since the material resists caking and clumping in low-moisture environments. Based on regular quality audits, clients delivering paints or high-value chemicals see almost no changes in melting point from storage — a far cry from cheaper phenolic analogs.

    Improving Through Real-World Feedback

    We know batch failures waste everybody’s time and money. That’s why every reported issue — crystallization, melting anomalies, unexpected interactions — gets tracked and traced back to the source. Operators on our plant floor keep logs and participate in feedback meetings, sharing what works and what slows down production. Suggestions from users in adhesives, sealants, or even additive masterbatches feed straight into our revised manuals and process sheets. Over the years, this loop has trimmed lead times, cut scrap rates, and let product development teams unlock more sophisticated applications.

    Environmental and Safety Concerns Addressed at the Manufacturing Level

    Our experience with chemical safety began long before stricter compliance regimes. Over the years, we improved dust-control systems to handle phenolic compounds like 2-Cyclohexyl-5-Methylphenol more safely. All storage and transfer lines use positive seals to prevent accidental vapor releases. On-site monitors and proper PPE for all shift workers eliminate exposure risks. By designing our process with real safety in mind, we avoid surprises, both inside our facility and in the hands of end users who must comply with their own environmental standards. Over time, we switched to more closed-loop cleaning and waste management, ensuring our footprint stays as low as possible.

    Trust Built on Experience, Not Marketing

    Trust doesn’t come from sales talk — it comes from actual performance, repeat orders, and honest feedback. We’ve been through cycles where a run of low-cost knockoffs hit the market, often imported without the necessary quality controls. Those too often lead to complaints on user lines: crystallization, gumming, strange colorations. Our team stands behind every shipment. We identify impurities at the microgram level and provide full support for any investigations into product performance. This isn’t extra service, just a normal part of real chemical manufacturing. We know who we are supplying, which processes they run, and what matters most for each product’s end use.

    Final Perspective from the Factory: Why We Keep Focusing on 2-Cyclohexyl-5-Methylphenol

    Focused improvement beats quantity every time. Over the last decade, as more sectors demand higher resilience and longer-lasting performance from their end products, our plant has prioritized compounds that offer measurable gains. 2-Cyclohexyl-5-Methylphenol stood out during internal trials for its exceptional stability and versatility. By controlling synthesis from start to finish, we bring something to the market that resists degradation, delivers reliable physical properties, and solves problems common with older phenol options. Every ton we ship carries years of practical knowledge and continual refinement — from the setup of our reactors to the real-world feedback of technical users across multiple industries. That is why formulators, polymer scientists, and process engineers continue to include our product in their most demanding projects.