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HS Code |
217841 |
| Chemical Name | 2-Cyclohexyl-5-Methylphenol |
| Molecular Formula | C13H18O |
| Cas Number | 5181-02-6 |
| Appearance | White to off-white solid |
| Melting Point | 71-73°C |
| Boiling Point | 314°C |
| Density | 1.03 g/cm³ |
| Solubility In Water | Insoluble |
| Structure | Cyclohexyl group at position 2, methyl group at position 5 on phenol ring |
| Synonyms | 2-Cyclohexyl-5-methylphenol; PCMX |
| Smiles | CC1=CC=C(C=C1O)C2CCCCC2 |
| Flash Point | 150°C |
| Refractive Index | 1.550 (estimated) |
| Usage | Antimicrobial agent |
As an accredited 2-Cyclohexyl-5-Methylphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, 100 g, sealed with screw cap, labeled with chemical name, hazard symbols, batch number, and supplier details. |
| Shipping | 2-Cyclohexyl-5-methylphenol should be shipped in tightly sealed containers, protected from moisture and direct sunlight. The shipment must comply with local and international regulations for chemicals. Proper labeling, documentation, and handling precautions are required to ensure safety during transit. Avoid extreme temperatures and keep away from incompatible substances. |
| Storage | Store **2-Cyclohexyl-5-Methylphenol** in a tightly closed container, in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Keep the storage area free from moisture and ignition sources. Ensure containers are clearly labeled and handled using appropriate personal protective equipment. Follow all relevant safety and chemical storage regulations. |
Applications of 2-Cyclohexyl-5-Methylphenol in Industrial Manufacturing2-Cyclohexyl-5-Methylphenol serves as a key specialty intermediate in several established industrial sectors. As the manufacturer, we supply this material to customers with advanced technical requirements relating to antimicrobial formulations, personal care preservatives, high-performance polymers, veterinary pharmaceutical synthesis, and specialty surface coatings. Below are major downstream application scenarios, each representing a concentrated real-world use with explicit industry practices. 1. Antimicrobial Preservatives for Industrial Cleaning FormulationsIndustrial cleaning product manufacturers rely on our material as a highly effective phenolic biocide to inhibit a broad spectrum of bacteria and fungi in aqueous and non-aqueous formulations. Its cyclohexyl and methyl-substituted phenol structure offers strong membrane-disruptive activity, supporting long-term preservation in high-contamination environments, even at low concentrations. Downstream producers incorporate the product directly during final blending of microbially sensitive formulations, maintaining compliance with leading chemical regulatory regimes. Industry compliance standards
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2. Personal Care Preservatives in Cosmetic and Toiletry ManufacturingPersonal care industry clients utilize this molecule as an active antimicrobial preservative in sophisticated leave-on and rinse-off formulations. Its specific activity against Gram-positive organisms makes it attractive for deodorant, shampoo, and hand wash development, particularly where paraben- or formaldehyde-free declarations are critical. Compound is dissolved in the oil or solubilizer phase and incorporated into the bulk mix at sub-0.5% levels to avoid regulatory ingredient cutoffs and maintain sensory profile parameters. Industry compliance standards
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3. Synthesis Building Block in Veterinary PharmaceuticalsVeterinary pharmaceutical manufacturers source this phenolic intermediate as a crucial building block for non-steroidal anti-inflammatory drugs (NSAIDs) and antimicrobial veterinary actives. Its molecular framework supports regioselective reactions during heterocyclic synthesis and esterification steps. Downstream integration most frequently occurs during the early-stage active pharmaceutical ingredient (API) manufacturing, where strict impurity profile controls are mandated by regulatory dossiers. Industry compliance standards
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4. High-Performance Polymer and Resin ModificationSpecialty polymer producers leverage 2-Cyclohexyl-5-Methylphenol as a reactive modifier, imparting both enhanced hydrolytic stability and antimicrobial attributes to thermoset and thermoplastic resins. Its inclusion as a co-monomer or chain stopper is critical in industrial polymerization for engineered materials used in medical device casings and other high-touch surfaces. Such modifications occur during controlled addition in the in situ polymer chain propagation step. Industry compliance standards
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5. Specialty Surface Coatings for Hygiene and ProtectionManufacturers of specialty industrial and institutional coatings formulate with this active to deliver durable, non-leaching antimicrobial properties. Applied primarily in paint and varnish systems designed for hospitals, laboratories, and high-traffic public spaces, the compound integrates into the pigment dispersion or final compounding step to assure homogenous distribution and maintained surface activity throughout the lifespan of the coating. Appropriate usage aligns with rigorous product labeling and efficacy substantiation requirements. Industry compliance standards
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Experience shapes how we approach chemical solutions. After decades of hands-on manufacturing, we have learned plenty about the small details that go into producing specialty phenol derivatives. 2-Cyclohexyl-5-Methylphenol stands out in our catalog for several reasons; it never falls into the generic range of phenolics most traders try to push. True utility in chemical manufacturing comes from understanding not just the structure, but the behavior in real-world applications.
We handle the raw materials and run the reactors ourselves. That means each batch of 2-Cyclohexyl-5-Methylphenol hits the shelf after real-time checks, not just a rubber-stamp certificate. In the plant, we see how cyclohexyl substitution brings new dimensions to the table. The methyl group adds subtle differences in terms of solubility and chemical reactivity. Our team knows these tweaks can make a world of difference in product development labs. Judged on appearance, you’ll see a clear or slightly off-white crystalline solid. You get a reliable melting point and consistent particle size, factors we check throughout the process.
Over the years, new product developers in coatings, polymers, and specialty biocides keep coming back to this compound for a reason. The cyclohexyl group brings steric bulk, which means the molecule can withstand harsher chemical environments without rapid degradation. Companies creating advanced antimicrobial formulations rely on this stability. On the manufacturing line, we’ve tested and compared it against common alkylphenols. Most break down faster under heat and sunlight; cyclohexyl-methyl variants like this show far greater long-term consistency, reducing the risk of off-odors or color drift in finished products.
Lab results matter, but so does experience. We measure melting point, purity, water content, and residual solvents in our own facility before we ship. Typical purity exceeds 99%. Our solvents and intermediates team pays careful attention to crystallization, since even minor impurities can throw off downstream reactions. You get a phenolic odor with moderate volatility — nothing overpowering, and easily handled in standard ventilated environments. We’ve found that the cyclohexyl group provides better processability in high-polymer environments, with less unexpected gellation compared to simple cresols or xylenols.
We have watched formulators experiment with dozens of phenolic compounds. 2-Cyclohexyl-5-Methylphenol works especially well as a building block for high-performance resins and stabilizers. Some clients use it directly as an antioxidant, seeking that balance between cost and resistance to oxidation. Others incorporate it as a modifier in epoxy systems, reporting smoother curing curves and fewer bubble-formation problems. Pharmaceutical developers sometimes explore its broader analogues, as similar reagents offer selective reactivity for specialized ligands or esters.
Old-school phenols like para-cresol or 2,6-xylenol have their place. We produced them for years and still run loads for bulk applications. In high-value sectors, they often fall short. 2-Cyclohexyl-5-Methylphenol fills the gap where greater steric hindrance and slightly higher molecular weight are critical. Unsubstituted methylphenols usually react too quickly, or offer poor compatibility with modern polymer blends. Cyclohexyl substitution allows tighter control of reaction rates, thermal stability, and melt behavior. This isn’t marketing spin — we’ve seen it ourselves while troubleshooting failures for customers who struggled with older phenol grades.
Consistency can make or break an industrial process. We control our process right down to temperature ramping and solvent removal. Each reactor run provides traceable lot records, checked by our shift chemists who know what variance in odor or color means on the next stage. Our quality team maintains digital and hands-on logs to spot trends long before a batch goes out. If one stage of raw material handling veers outside target spec, we isolate and rework it before shipment. Stainless steel reactors and filtrations with food-grade seals keep contamination down. These details get missed in secondary markets but matter every single day on production floors.
Most distributors never see long-term user complaints — but manufacturers do. Customers come to us with thermal stability challenges for finished adhesives exposed to year-round temperature swings. We’ve documented how 2-Cyclohexyl-5-Methylphenol’s balance of rigidity and moderate flexibility translates into lower failure rates after months of exposure. Handling spills, optimizing for large-scale mixers, and scaling up pilot batches all show what a difference raw material choice makes. Problems with off-spec material don’t stay hidden in bulk shipping either — they surface at the user’s end with gellation or crystallization issues that can trace back to a single missed control point at our plant.
We prefer straightforward feedback over layers of middlemen. Years of experience with this compound allow us to supply technical support informed by both production analytics and customer experience. As new markets like high-durability construction polymers and outdoor-use plastics expand, we keep seeing the specific advantage of cyclohexyl-modified phenols in physical and chemical testing. Manufacturing is real work — it brings real data, not just sales promises. When epoxies or adhesives based on this molecule outperform common blends under stress, our clients share those results with us. We use this information to fine-tune tank cleaning, drying routines, and filtration during subsequent runs.
We admit that specialty chemicals bring new handling considerations. 2-Cyclohexyl-5-Methylphenol changes the flow viscosity of resin blends. Our operators monitor filtration speed in order to optimize downstream production for coatings and sealants customers. The crystalline form travels well, but in extremely humid conditions, we recommend additional packaging layers. Over time, we found certain binder packages in paints react more slowly with cyclohexyl-modified phenols, which helps users extend pot life but can require extra care in curing schedules. These are notes we track and share with formulators who need granular advice on adapting their processes.
Early on, we faced our share of headaches trying to fit this innovation into aging equipment. Pumps set for lower-viscosity fluids needed careful adjustment. Initial scale-ups found that the thicker solution sometimes left residues in bends and fittings; we switched up agitation protocols and extended rinse times. Plant maintenance staff learned quickly to check for traces of cyclohexyl residues when routine cleaning didn’t fully clear the lines. Most users adapt within a couple of batches — our technical team checks in directly with industrial users to help dial in these parameters.
Jumping from low-cost alkylphenols to a more sophisticated structure often brings questions about value. Seeing the proof firsthand, the added stability and controlled reactivity pay off in higher yields and reduced rework. Resin plants benefit from lower yellowing risks. Polymer clients have fewer issues with batch-to-batch color drift, especially under UV exposure. Bulk methylphenols rarely match up in these categories. In antimicrobial applications, cyclohexyl-methyl phenols don’t degrade as quickly, resisting breakdown even in aggressive formulations packed with strong acids or bleach. This saves time and cost in quality complaints.
Leading resin formulators routinely call on us to provide larger particle-size lots, supporting bulk production of weather-resistant plastics. Labs working on electrical insulators use fine-graded batches, noting how the compound’s stability translates to greater dielectric performance. For chemical intermediates, 2-Cyclohexyl-5-Methylphenol steps in where substituted cresols become too reactive or volatize at inconvenient temperatures. Clients have explored it in biocidal polymers and wood preservatives — anywhere durability and slow degradation are non-negotiable. We’ve solved labeling concerns by working with labs on clearer documentation of molecular structure for compliance reviews.
Our warehouses use sealed containers resistant to light and humidity, since cyclohexyl-methyl phenols retain best stability in these conditions. We handle large drums using closed transfer, which reduces time in the open air. To avoid cross-contamination with halogenated solvents, we dedicate filtration trains and packaging lines. On user sites, best practice involves climate-controlled storage, since the material resists caking and clumping in low-moisture environments. Based on regular quality audits, clients delivering paints or high-value chemicals see almost no changes in melting point from storage — a far cry from cheaper phenolic analogs.
We know batch failures waste everybody’s time and money. That’s why every reported issue — crystallization, melting anomalies, unexpected interactions — gets tracked and traced back to the source. Operators on our plant floor keep logs and participate in feedback meetings, sharing what works and what slows down production. Suggestions from users in adhesives, sealants, or even additive masterbatches feed straight into our revised manuals and process sheets. Over the years, this loop has trimmed lead times, cut scrap rates, and let product development teams unlock more sophisticated applications.
Our experience with chemical safety began long before stricter compliance regimes. Over the years, we improved dust-control systems to handle phenolic compounds like 2-Cyclohexyl-5-Methylphenol more safely. All storage and transfer lines use positive seals to prevent accidental vapor releases. On-site monitors and proper PPE for all shift workers eliminate exposure risks. By designing our process with real safety in mind, we avoid surprises, both inside our facility and in the hands of end users who must comply with their own environmental standards. Over time, we switched to more closed-loop cleaning and waste management, ensuring our footprint stays as low as possible.
Trust doesn’t come from sales talk — it comes from actual performance, repeat orders, and honest feedback. We’ve been through cycles where a run of low-cost knockoffs hit the market, often imported without the necessary quality controls. Those too often lead to complaints on user lines: crystallization, gumming, strange colorations. Our team stands behind every shipment. We identify impurities at the microgram level and provide full support for any investigations into product performance. This isn’t extra service, just a normal part of real chemical manufacturing. We know who we are supplying, which processes they run, and what matters most for each product’s end use.
Focused improvement beats quantity every time. Over the last decade, as more sectors demand higher resilience and longer-lasting performance from their end products, our plant has prioritized compounds that offer measurable gains. 2-Cyclohexyl-5-Methylphenol stood out during internal trials for its exceptional stability and versatility. By controlling synthesis from start to finish, we bring something to the market that resists degradation, delivers reliable physical properties, and solves problems common with older phenol options. Every ton we ship carries years of practical knowledge and continual refinement — from the setup of our reactors to the real-world feedback of technical users across multiple industries. That is why formulators, polymer scientists, and process engineers continue to include our product in their most demanding projects.