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2-Cyano-Phenothiazine

    • Product Name 2-Cyano-Phenothiazine
    • Alias 2-Cyanophenothiazin
    • Einecs 629-120-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    968377

    Molecular Formula C13H8N2S
    Molecular Weight 224.28 g/mol
    Cas Number 26571-47-3
    Appearance Yellow to orange solid
    Melting Point 171-175°C
    Solubility Slightly soluble in organic solvents
    Purity Usually ≥98%
    Storage Conditions Store in a cool, dry place, away from light
    Smiles N#CC1=CC2=CC=CC=C2SC3=CC=CC=C13
    Inchi InChI=1S/C13H8N2S/c14-9-8-10-12-6-2-1-5-11(12)16-13-7-3-4-15-13(10)9/h1-8H
    Hazard Statements May be harmful if swallowed

    As an accredited 2-Cyano-Phenothiazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 5-gram 2-Cyano-Phenothiazine is packaged in a sealed amber glass bottle with a secure screw cap and clear labeling.
    Shipping 2-Cyano-Phenothiazine is shipped in tightly sealed containers, protected from light and moisture. It is classified as a chemical reagent and handled according to standard hazardous material regulations. Proper labeling, documentation, and protective packaging are provided to ensure compliance with international shipping and safety standards during transport.
    Storage 2-Cyano-Phenothiazine should be stored in a cool, dry, and well-ventilated area, away from direct sunlight, heat, and sources of ignition. Keep the container tightly closed and clearly labeled. Store separately from incompatible materials such as strong oxidizers and acids. Ensure proper secondary containment to avoid spills and use appropriate chemical-resistant containers to prevent decomposition or contamination.
    Application of 2-Cyano-Phenothiazine

    Applications of 2-Cyano-Phenothiazine in Industrial Manufacturing

    2-Cyano-Phenothiazine serves as a critical intermediate in several high-value industrial sectors, supporting efficient synthesis and formulation of advanced chemical products. Below we describe targeted downstream scenarios where this material brings distinct technical and compliance benefits throughout production cycles.

    1. Photoinitiators for UV-Curing Systems

    Engineered molecules based on the phenothiazine core, such as 2-Cyano-Phenothiazine, have become foundational in the synthesis of advanced photoinitiators used in UV-curable inks, coatings, and adhesives. Downstream compounders introduce the raw material via multi-step reactions involving alkylation and condensation, targeting photoinitiators with narrow absorption band tuning and high quantum yield. Ongoing regulatory scrutiny in the UV curing sector requires precise processing to ensure product purity and minimal migration in end-use applications. Formulators balance usage levels based on the end cure rate, targeted film thickness, and the desired mechanical properties of the coated or printed substrates.

    Industry compliance standards

    • REACH (EC 1907/2006)
    • GHS labelling for handling photoreactive chemicals
    • Swiss Ordinance on Materials and Articles (SR 817.023.21) for coatings in food contact
    • ISO 28219:2017 for UV inks labelling and traceability

    Typical usage ratio

    • 1.0–5.0% by weight in photoinitiator synthesis step; downstream formulation in ink/coating: 0.2–3.0% w/w, depending on film thickness and cure requirements

    Downstream process integration

    • Charged during photoinitiator core intermediate synthesis prior to alkylation
    • Integrated in multi-component UV ink or resin mixing after photoinitiator purification

    Final product types

    • UV-curable inkjet inks for digital printing
    • Industrial UV-cured coatings for electronics, automotive plastics, wood finishes
    • Adhesives used in electronics assembly and medical devices

    2. Advanced OLED and Display Material Precursors

    The electron-donating and conjugated structure of phenothiazine derivatives make them sought after as building blocks for organic light-emitting diode (OLED) emitters and charge transport materials. Commercial OLED layer stacks benefit from the introduction of cyano-substituted phenothiazines during key stages of organic molecule construction, improving device charge balance and extending operational lifetime. R&D and quality assurance teams control precursor specification tightly, particularly regarding purity and trace impurity content, to meet the electronics sector’s strict reliability expectations.

    Industry compliance standards

    • IEC 62471:2006 for photobiological safety
    • RoHS Directive 2011/65/EU
    • JEITA/EIAJ standards for organic semiconductors
    • ISO 9001:2015 quality systems for electronic materials

    Typical usage ratio

    • Recorded loading is 2–10 mol% in charge transport or emissive layer precursor step; final functional layer: 0.5–5 wt% depending on device structure

    Downstream process integration

    • Introduced as a ring-structure intermediate in arylation or coupling reactions for OLED molecule synthesis
    • Applied in dopant or host material solution blending prior to vacuum deposition or inkjet printing onto device substrates

    Final product types

    • Organic LEDs for mobile phone displays, televisions
    • Active matrix OLED panels for automotive and high-end monitors
    • Wearable display modules

    3. Pharmaceutical Intermediate for Antipsychotic APIs

    Pharmaceutical manufacturers utilize 2-Cyano-Phenothiazine as a key intermediate in the synthesis of several antipsychotic drug substances, where the cyano group facilitates further functionalization of the heterocyclic core. Downstream partners conduct stepwise condensations and substitutions under strict current Good Manufacturing Practice (cGMP) guidelines, and analytical teams perform in-process control for residual solvents and isomeric purity. Handling, storage, and documentation adhere to pharmaceutical industry audit requirements, especially in regulated markets (EU, US, Japan).

    Industry compliance standards

    • ICH Q7 (GMP for APIs)
    • USP–NF monograph for phenothiazine derivatives
    • 21 CFR Part 211 for finished pharmaceuticals
    • EU Guidelines for GMP (Annex 1 and 2)

    Typical usage ratio

    • Stoichiometric to slight excess versus the secondary amine/alkyl chloride, tailored by scale and impurity profile requirements

    Downstream process integration

    • Added in initial heterocycle building step before chlorination or amination
    • Usually isolated and subjected to sequential modifications (e.g., N-alkylation, halogenation) for final API production

    Final product types

    • Antipsychotic active pharmaceutical ingredients (e.g., perphenazine, fluphenazine)
    • Bulk API forms for contract pharmaceutical manufacturers
    • Tablet and injectable pre-formulation intermediates

    4. Dye and Pigment Intermediate for Technical Textiles

    Chemical processors in the dye and pigment segment utilize cyano group-substituted phenothiazine scaffolds for the production of high-performance vat and disperse dyes. The compound’s cyclic sulfur-nitrogen system provides favorable shade development and chemical resistance that meet the technical textiles industry’s demanding requirements. Strict control of side reactions prevents unwanted by-products affecting fastness or dispersion. Regulatory compliance in coloration processes focuses on limiting residual unreacted intermediates and monitoring effluent for environmental discharge standards.

    Industry compliance standards

    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals)
    • Oeko-Tex Standard 100 for finished textile safety
    • ISO 105 family for color fastness testing
    • REACH Annex XVII for restricted substances

    Typical usage ratio

    • Typically 5–15% of dye intermediate batch mass, with fine-tuning for target hue depth and stability

    Downstream process integration

    • Introduced as a core chromophore modifier at initial dye molecule ring closure
    • Further processed through sulfonation/coupling before drying and blending for pigment dispersions

    Final product types

    • Vat dyes for denim, industrial workwear
    • Disperse dyes for synthetic fiber coloration
    • Specialty pigments for high-performance technical coatings

    5. Polymer Stabilizer Intermediate for Engineering Plastics

    The unique electronic structure of the material enables downstream manufacturers to prepare polymer stabilizers and antioxidants for engineering thermoplastics. The phenothiazine core, functionalized via cyano substitution, provides stabilization against UV degradation and oxidative processes. Process engineers introduce the intermediate during complex multi-step synthesis of hindered amine light stabilizers or benzotriazole-based additives, closely monitoring residual monomer and thermal stability parameters according to international plastics standards.

    Industry compliance standards

    • FDA 21 CFR §178.2010 (indirect food additives: polymer stabilizers)
    • UL 746C for polymeric component safety
    • ISO 4892-2 for light aging testing of plastics
    • RoHS for restrictions on hazardous substances in consumer electronics

    Typical usage ratio

    • Employed at 0.5–3.0% w/w of polymer stabilizer synthesis batch; final additive loading: 0.1–1.0% by weight in compounder pellet blend, adjusted by polymer matrix type

    Downstream process integration

    • Inserted during condensation or substitution stage in stabilizer molecule build-up
    • Combined with base resin during masterbatch compounding or hot-melt blending for ready-to-use plastic pellets

    Final product types

    • Injection molding and extrusion-grade polyamide, PBT, and polycarbonate compounds
    • Plastic parts for automotive under-hood applications
    • Outdoor enclosure and telecommunications housings
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    Certification & Compliance
    More Introduction

    2-Cyano-Phenothiazine: Expanding the Capabilities of Functional Materials

    Practical Experience with 2-Cyano-Phenothiazine

    Manufacturing high-purity 2-Cyano-Phenothiazine takes more than following a recipe. Our production team meets challenges at every stage, from consistent crystallization to the removal of colored by-products that come from subtle variations in raw material batches. Our years in process optimization let us manage raw material supply fluctuations while maintaining product consistency. Even the water quality entering the reactors produces tangible differences at scale. That’s the reality in the plant, far away from any theoretical process flow diagram.

    During synthesis, ensuring the stability of the cyano group on the phenothiazine backbone is central. Side-reactions like hydrolysis or oxidative dimerization can crop up without warning if microenvironmental controls slip. Someone unfamiliar with the plant’s rhythms might assume a clean conversion is trivial; real-world chemistry always brings new surprises. We’ve built analytical checkpoints—HPLC and UV-VIS analysis—across our batch lines to deliver a repeatable product. It’s what serious customers in electronics, pharmaceuticals, or specialty coatings expect.

    Why 2-Cyano-Phenothiazine Matters in Modern Synthesis

    Phenothiazine derivatives have shaped fine chemicals for decades, from photosensitive compounds to smart dyes and advanced intermediates. Introducing the cyano group into the 2-position changes the electronic properties of the molecule. That one substitution opens up new routes in organic synthesis where standard phenothiazine falls short. Downstream, this core difference matters for end-users designing new materials and processes.

    2-Cyano-Phenothiazine stands out in electron transfer and redox catalysis. Chemists leveraging its cyano functionality target higher electron affinity in OLED research, photocatalyst development, or fine chemical synthesis. Higher electron affinity allows more efficient charge transfer, and the molecule brings this without introducing fussy or unstable substituents. Reliability goes up, and so does innovation.

    Understanding Model and Specifications

    Our flagship production line for 2-Cyano-Phenothiazine operates at a multi-ton scale and emphasizes sharp lot-to-lot reproducibility. Color, melting range, and spectral signature reflect a deliberate investment in batch analytics. Modern specifications address purity thresholds above 98%, with attention to moisture content and polymorph identification. Traces of unreacted phenothiazine or isomeric contaminants stay well below critical limits, as shown by our chromatographic profiles.

    Early feedback from customers tells us a simple description of material form makes a difference on the shop floor. Our batches typically arrive as a pale yellow crystalline powder that pours freely, thanks to careful drying and sieving at the end of synthesis. This granular detail cuts handling surprises for formulators in the lab and plant. Some buyers expect pre-weighed aliquots, which we provide on contract, helping to save valuable time and avoid waste. These small steps in keeping hands-on workflows efficient—rather than only resting on statistical claims about purity—keep production lines moving.

    Where 2-Cyano Differentiates From Other Phenothiazines

    Packing a cyano group onto the phenothiazine system creates more than superficial differences. Chemically, the 2-cyano derivative earns its reputation by shifting electron density, raising the reduction potential compared to base phenothiazine. Translating lab findings into scalable production, our own team has measured consistent spectral shifts in both UV-Vis and electrochemical assays. What starts as a minor difference on paper grows into a decisive advantage in real-world applications demanding precision electron transfer or charge separation.

    Experience tells us formulators sometimes try to swap in cheaper phenothiazine versions in pursuit of cost savings, especially on early project stages. This almost always leads to underwhelming results for applications rooted in electronic characteristics. In the photoinitiator world, the altered absorption maximum of 2-Cyano-Phenothiazine produces higher efficiency. In pharmaceutical synthesis, selective functionalization routes rely on that same electronic tuning, offering cleaner product streams in fewer steps. Trying to substitute basic phenothiazine often sets development programs back months as screening confirms what seasoned chemists already know. The investment in a specialized derivative creates longer-term savings and reliability.

    The Strategic Role in Photocatalysis and Redox Chemistry

    One of the most promising uses for 2-Cyano-Phenothiazine curves through the landscape of organic photoredox catalysis. We support industrial R&D teams fine-tuning photoredox processes, where subtle variations in catalyst electronic structure shift yields and selectivities. The cyano group positions the molecule within reach of visible-light activation wavelengths. Synthetic labs working with aryl halide activations, photo-initiated radical cyclizations, or C–N bond-forming reactions share their data back with us. Performance improvements show up as increased throughput, fewer by-products, and—on a practical level—reduced need for repeat purifications.

    In our own pilot lines, we tested side-by-side runs using parent phenothiazine versus the cyano-functionalized molecule. Instrumental analysis verified what process operators saw: faster conversions, lower light dose requirements, and simplified downstream separations for the cyano derivative. That success translates into less downtime and a smaller waste stream, both of which plant managers value just as much as bench chemists do. These differences may not jump out in a small-scale academic study, but they reshape economics at commercial volume.

    How We Optimize for Customer Usage

    Field feedback shapes how we refine each batch—not just once but as a living process. Our collaboration with end-users flags new requirements, whether motivated by evolving regulatory standards or changes in how customers process materials. For example, trace metal residues from earlier synthetic routes tended to interfere in electronics-grade applications. We responded by switching reducing agents and upgrading purification steps, keeping final metal content below single-digit ppm thresholds. The resulting improvements have helped several partners ramp up production of optoelectronic devices with fewer QA-related callbacks.

    People encountering 2-Cyano-Phenothiazine for the first time sometimes expect the same handling profile as other nitrogen-heterocycles. Our technical support team often gets calls about storage, stability under light, and solvent compatibility. Years of shelf-life and photostability testing paint a clear picture: limiting UV exposure and controlling humidity keeps product performance predictable for much longer. We recommend polyethylene-lined containers and inert-atmosphere storage not as a generic precaution, but as lessons learned from batches that saw color shifts or agglomeration under less controlled warehouse conditions.

    Partnering with R&D for Next Generation Applications

    As upstream manufacturers, we don’t just wait for orders. Our labs regularly work in tandem with R&D partners tackling areas like organic electronics, advanced lithography, and photochemical synthesis. Some teams focus on solar cell development, using 2-Cyano-Phenothiazine as an electron acceptor in organic photovoltaic blends. Others explore it as a mediator or dopant in hole-transport layers, banking on the molecular affinity shifts unique to the cyano substitution. Our shared work includes detailed structure-property studies, freshly synthesized analogs, and regularly updated spectral libraries so collaborators aren’t working blind.

    Active communication between our chemists and customer engineers flags issues much faster than through formal complaint channels. One client in OLED manufacture struggled with batch-to-batch differences in device lifetimes. A deep-dive, hands-on session in their facility mapped the problem to ultra-trace differences in isomeric impurity profiles. Adjusting the fractionation stage of our process eliminated the problem. This direct and ongoing collaboration forms the practical core of enduring quality.

    Meeting Changing Industrial Trends and Compliance Needs

    As environmental regulations stiffen and demand shifts toward greener chemistry, we’ve evolved our production cycle to minimize waste and solvent emissions. Our upgraded lines recover and recycle more solvent at every batch, dropping total waste and corresponding disposal costs. For industries sensitive to process by-products—microelectronics firms, advanced pharmaceutical process chemists—this upfront effort removes friction later on during regulatory reviews.

    We routinely test each lot against international purity standards and provide detailed supporting data—analysis by GC-MS, NMR, and metal content screening. Our experience shows buyers rarely rely on summaries; instead they pull full analytical reports when fine-tuning sensitive applications or submitting product dossiers to regulators. Open access to this depth of information builds trust and speeds up their own compliance efforts.

    Addressing Customer Challenges Directly

    Real-world manufacturing demands flexibility, not dogma. Customers scaling new syntheses share obstacles, from unexpected solubility issues to reactivity quirks that only appear on the kilogram scale. Our technical support staff includes plant chemists who have seen these process variables up close. For one partner scaling up a photoinitiator blend, minor water residues in the 2-Cyano-Phenothiazine batches led to batch-to-batch mixing issues. Swapping out a drying step, under vacuum and at a specific temperature curve, resolved the issue and normalized their process yields.

    Process chemists who have tried adjusting reaction conditions around the quirks of generic phenothiazine derivatives have circled back to our team after seeing limited improvements. With 2-Cyano-Phenothiazine, they can directly fine-tune activation energies in light-driven reactions, for example, or extend performance windows in organic solar film fabrication. These changes accumulate real cost savings and improve output reliability, especially when extended over months or years of production.

    Where 2-Cyano-Phenothiazine Lands in Next-Generation Chemistry

    Our own downstream partners continue to surprise us, as they unearth uses outside legacy applications. Some have begun exploring the compound for dye-sensitized photoelectrochemical systems, leveraging the strong light absorption and fast charge relocation. Others have trialed it as a precursor for heterocyclic construction in pharmaceutical building blocks, riding the added reactivity of the cyano substituent.

    While some might overlook the significance of a single functional group, bench chemists and product formulators see how this translates into differentiated reaction rates, cleaner product streams, and a broader accessible reaction landscape. Plenty of familiar nitrogen-containing scaffolds support the industry, but the edge given by a tuned substituent can mark the difference between experimental success and commercial viability.

    Practical Handling and Storage from a Manufacturer’s Perspective

    Unlike intermediates that tolerate significant operational abuse, 2-Cyano-Phenothiazine requires deliberate care in handling and storage. We moved away from cardboard drums and implemented UV-blocking, polyethylene-coated vessels after early shipments showed quality drift in less protected packaging. Those lessons, learned painfully on the receiving dock and at QA check-in, now inform every new supply contract. Delays and caked material can cripple high-throughput downstream syntheses.

    Plant operators appreciate straightforward guidance. Clear labeling for storage temperature, moisture sensitivity, and light exposure accompanies every package. At the same time, we maintain a technical support line for in-process troubleshooting—often solving user-side issues with brief recommendations from our experienced operations team. These practices come from years of direct dialog with our customers rather than generic template guidance.

    Comparing Real Performance with Competing Materials

    Alternative phenothiazine derivatives and other aromatic nitrogen systems have their uses, but side-by-side trials draw out clear distinctions in photochemical, redox, and organic electronics experiments. Sourcing lower-cost analogues from generic supply brokers ended up producing inconsistent catalytic activity. Complex downstream purification requirements and uncertain stability eat into project budgets.

    Our 2-Cyano-Phenothiazine, consistently processed and validated, has set a proven benchmark in several customer studies. Formulators comparing product performance under demanding conditions see less batch rework and greater process predictability, raising their own throughput. For researchers integrating the compound into iterative R&D cycles—where feedback loops can span days, not weeks—having a consistent and responsive supply chain adds unexpected momentum.

    Continuous Improvement in Manufacturing

    Change on the plant floor never happens automatically. We maintain a seasoned team familiar with both synthetic chemistry and hands-on industrial troubleshooting, who watch for bottlenecks and quality drift before they filter out into customer complaints. By working with customers to gather return data from real production runs, our team can tweak process conditions, update purification steps, and recalibrate analytical equipment rapidly.

    This hands-on approach stretches from our QA lab to the late-shift operator, tracking and responding to outlier data before they become routine. Investment in spectroscopic monitoring, solvent recycling installations, and direct feedback keeps failure rates low—even as throughput increases. Evidence of these cumulative improvements lands in faster batch release, tighter process windows, and growing downstream customer loyalty.

    A Manufacturer’s Perspective on Market Evolution

    Market demand for specialized phenothiazine derivatives shows no signs of slowing, as industries move toward performance materials that offer unique electrochemical or photophysical profiles. 2-Cyano-Phenothiazine, once considered a niche intermediate, now finds use in mainstream photoredox and electronics processes. We continue shaping our production and support capabilities around this trend, keeping communication lines open with formulation chemists and production managers. Demand spikes have taught us that maintaining excess capacity beats trying to chase short-term supply surges with an overcommitted plant.

    As downstream sectors tighten process tolerances and push toward greener, high-performance chemistry, our manufacturing strategy revolves around more than batch stats or regulatory compliance checkboxes. By folding broad practical experience into daily plant operation, and by listening to the evolving needs and pain points of real users, we continue to produce a 2-Cyano-Phenothiazine product that advances both new research and commercial projects.