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2-Coumaranone

    • Product Name 2-Coumaranone
    • Alias 3,4-Dihydro-1-benzopyran-2-one
    • Einecs 202-313-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    VTB
    Specifications

    HS Code

    571320

    Name 2-Coumaranone
    Other Names 2H-1-Benzopyran-2-one
    Molecular Formula C8H6O2
    Molar Mass 134.13 g/mol
    Appearance White to pale yellow crystalline solid
    Melting Point 68-70°C
    Boiling Point 274°C
    Density 1.243 g/cm³
    Cas Number 87-29-6
    Solubility In Water Slightly soluble
    Flash Point 120°C
    Chemical Structure C1=CC=C2C(=C1)C=CO2

    As an accredited 2-Coumaranone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Coumaranone, 100g: Supplied in an amber glass bottle with a secure cap, labeled with chemical details, hazard warnings, and batch number.
    Shipping 2-Coumaranone is shipped in tightly sealed containers, protected from moisture and light, and kept in a cool, well-ventilated environment. Standard chemical safety protocols are followed, including proper labeling and documentation. Transport complies with relevant regulations for non-hazardous chemicals to ensure safety and prevent contamination or degradation during transit.
    Storage 2-Coumaranone should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizing agents. Keep the container tightly closed and protected from light. Store at room temperature or below, in a chemical storage cabinet designed for organic compounds, to prevent moisture absorption and potential degradation.
    Application of 2-Coumaranone

    Applications of 2-Coumaranone in Industrial Manufacturing

    2-Coumaranone, synthesized and supplied by our facilities under strict quality control, serves as a key building block in several industrial sectors. This intermediate impacts downstream manufacturing in specialties such as pharmaceuticals, agrochemicals, dyes, perfumery, and polymer additives. Each application requires tailored handling for compliance, process integration, and specific end-product requirements.

    1. Pharmaceutical Intermediate Synthesis

    Pharmaceutical manufacturers use this lactone as a critical intermediate for the synthesis of several active pharmaceutical ingredients (APIs), with a focus on coumarin-based anticoagulants and other therapeutic agents. Our product complies with pharmacopeial standards, and we manage batch traceability to accommodate regulatory audits. Process chemists introduce this material during multi-step API syntheses, ensuring controlled reaction conditions for the safe conversion to target molecules. The resulting compounds undergo final crystallization and purification prior to formulation, packaging, and release.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
    • EU GMP Part II: Basic Requirements for Active Substances
    • USP–NF and Ph. Eur. monographs (where applicable to final API)
    • FDA guideline 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)

    Typical usage ratio

    • 5–35% molar ratio as an intermediate, adjusted by target molecule yield and process route
    • Ratios determined by stepwise synthesis batch size and conversion efficiency

    Downstream process integration

    • Introduced at the initial or second synthetic stage for oxazolone rings or coumarin-based drug scaffolds
    • Reaction in solvent phase with alkali or acid catalysts, followed by extraction
    • Post-reaction hydrolysis and purification on chromatography columns or crystallization tanks
    • Strict in-process control for residual solvents, intermediates, and impurities

    Final product types

    • Coumarin-derived anticoagulants (e.g., warfarin, acenocoumarol)
    • Pharmaceutical grade coumarin APIs
    • Other regulated specialty pharmaceutical intermediates
    • Research compounds for structure-activity relationship studies

    2. Agrochemical Raw Material

    Agrochemical companies employ this precursor for synthesis of select fungicides and herbicides based on coumarin or related benzopyrone frameworks. Our technical grade material meets REACH and specific industry tolerances for allowable trace contaminants. The product enters multi-stage reactions under controlled atmospheres at agrochemical plants, usually combined with halogenation or alkylation reagents. The output consists of concentrated technical mixtures, which undergo formulation with carriers or surfactants prior to packaging for agricultural end use.

    Industry compliance standards

    • EU REACH Regulation (EC) No 1907/2006
    • OECD Guidelines for the Testing of Chemicals
    • ISO 9001:2015 Quality Management Systems
    • Global GAP Crop Protection Product Safety framework

    Typical usage ratio

    • Between 10–25% by weight as a base structure in technical synthesis
    • Adjusted according to target fungicide or herbicide active loading

    Downstream process integration

    • Dosed in primary reactor during initial benzopyrone ring functionalization
    • Halogenation, methylation, and esterification steps follow initial condensation
    • Solvent recovery and by-product neutralization prior to isolation
    • Bulk technical concentrate standardized for active ingredient potency

    Final product types

    • Coumarin-based fungicide technicals (e.g., certain benzopyrone analogues)
    • Herbicide actives with lactone backbones
    • Intermediate blends for formulated crop protection products
    • Seed treatment active ingredients

    3. Colorant and Dye Intermediate

    Manufacturers in the dye and colorant industry select this compound as a foundation for synthesizing fluorescent and vat dyes, where lactone-containing scaffolds provide high lightfastness and tinctorial strength. Production lines conform to relevant dye industry assessment protocols and environmental discharge norms. Processing typically starts with sulfonation or phosphorylation of the molecule, and continues with stepwise coupling to create the desired chromophores. Subsequent milling and blending yield dye powders or pastes for industrial or textile application.

    Industry compliance standards

    • OEKO-TEX Standard 100 Class I-IV (textile chemical safety)
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals)
    • EU REACH Annex XVII on restricted azo dyes
    • ISO 14001 Environmental Management for manufacturing sites

    Typical usage ratio

    • 15–30% mass ratio in chromophore core structure synthesis
    • Varies with color shade depth and intended fastness properties

    Downstream process integration

    • Charged directly into reactor vessels for condensation with sulfonating agents
    • Followed by multi-step coupling to build extended aromatic systems
    • Vacuum drying and granulation of dye intermediates
    • In-process tests for color value, stability, and residue profiles

    Final product types

    • Coumarin-based fluorescent dyes
    • Vat dyes for cotton and viscose textiles
    • Specialty pigments for plastics and coatings
    • Paper brighteners for high-grade printing stock

    4. Fragrance and Flavour Additive Production

    Fragrance and flavour houses use this lactone as a precursor for coumarin derivatives in both perfumery and food additive manufacturing. Our supply matches IFRA (International Fragrance Association) and FEMA (Flavor and Extract Manufacturers Association) substance controls. Technicians introduce the intermediate in esterification or oxidative coupling processes, generating targeted aroma compounds for further blending and stabilization. Finished products are subject to rigorous GC-MS purity analysis and cross-checks against prohibited substances lists.

    Industry compliance standards

    • IFRA Standards and Guidelines (perfume safety/regulatory)
    • FEMA GRAS (Generally Recognized as Safe) listing
    • Regulation (EC) No 1334/2008 on flavourings
    • US FDA 21 CFR Parts 170 and 182 for food additive substances

    Typical usage ratio

    • 5–20% by weight for fragrance intermediate synthesis
    • Ratio managed by desired olfactory intensity or flavour note target

    Downstream process integration

    • Batch-wise entry into fragrance mixing reactors for conversion to target coumarin compounds
    • Esterification with alcohols or ketone derivatives under mild conditions
    • Vacuum stripping for residual solvent removal
    • Blending and aging in stainless steel vessels before packaging

    Final product types

    • Synthetic coumarin fragrance bases for fine perfumery
    • Industrial aroma chemicals for soaps and detergents
    • Flavoring agents for confectionery and beverages (subject to regulatory lists)
    • Blended aroma compositions in air fresheners and candles

    5. Polymer Additive Manufacturing

    The compound functions as a polymerization modifier and performance additive in engineering plastics and resins. Our production aligns with RoHS and SVHC monitoring for use in downstream processes. Industrial extrusion lines introduce the material during melt blending to enhance UV stability and mechanical properties of final products. Attention to precise dosing ensures thermal stability and prevents negative effects on polymer processing characteristics. Finished masterbatches and compounded resins undergo testing for mechanical performance and regulatory compliance before shipping.

    Industry compliance standards

    • EU RoHS Directive 2011/65/EU
    • EU REACH SVHC (Substances of Very High Concern)
    • ISO 9001:2015 for manufacturing traceability
    • UL 94 flammability guidelines (for plastics)

    Typical usage ratio

    • 0.5–2.0% by weight in polymer formulations
    • Adjustable depending on base resin type and required additive effect

    Downstream process integration

    • Incorporated during masterbatch blending with polyolefins, polystyrene, or engineering resins
    • Direct dosing in extrusion or injection molding processes
    • Monitored for dispersion and thermal degradation in compounding lines
    • Post-production QA for migration and polymer compatibility

    Final product types

    • UV-stabilized plastic parts and panels
    • Performance-enhanced ABS and polystyrene components
    • Polymer masterbatches for automotive and electronics industries
    • Plastic additives for construction and consumer goods
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    Competitive 2-Coumaranone prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    2-Coumaranone: A Chemist’s Workhorse

    Our Experience with 2-Coumaranone Production

    Working every day with 2-Coumaranone, it becomes clear why this compound stands out in the chemical industry. Our shop floors have witnessed both the simplicity and challenge tied to its manufacture: from managing raw material quality, controlling reaction temperatures, and ensuring minimal byproducts, there is a hands-on reality to producing this lactone that most only read about. These decisions matter, especially in large-scale runs, where a momentary temperature shift affects both yield and purity. Real equipment and real people keep the operation running, not just theoretical process flows from a textbook.

    Our 2-Coumaranone comes in powder and crystalline forms, typically white to pale yellow. Packaging choices grew out of feedback from those who actually use this compound in their day-to-day operations: robust lining, manageable batch weights, and minimal contamination risk. Over years, we have settled on specifications reflecting what works on the ground for formulators, not just what looks good on a data sheet.

    Why 2-Coumaranone Matters for the Polymer Industry

    No boardroom meeting has taught us as much about 2-Coumaranone as working shoulder to shoulder with technicians from tire, resin, and adhesive plants. In the rubber industry, 2-Coumaranone brings some unique value. Blending it into the manufacture of synthetic rubbers such as SBR and BR can alter performance characteristics, especially flexibility under different temperatures and improved resistance to weathering. Colleagues in those plants report longer life cycles and improved overall resilience of the end product, especially in demanding automotive applications.

    We watch our product show its worth in resin and coating lines. 2-Coumaranone-based resins offer excellent gloss, strong adhesion, and consistent performance in packaging and printing inks. Makers of book bindings and heat-seal adhesives favor it because it sets quickly and holds under stress. One batch to the next, plant operators appreciate not having to slow down the line due to unpredictable curing properties or off-colors creeping in.

    The Path from Raw Material to Finished Product

    We source phenol derivatives and follow a tightly monitored catalytic cyclization process. Over time, we’ve invested in refining equipment for vapor-phase reactions. Our equipment teams identified how small design tweaks — from heat exchanger placement to direct expansion cooling — affect final yield, energy use, and product purity. Avoiding off-odor byproducts and tars also calls for hands-on process and filtration improvements that can only be learned after hundreds of runs.

    Solvent use turns some heads, so we have moved toward recycling wherever we can. Spent solvents are cleaned and returned for process reuse instead of being disposed. This both shrinks costs and waste. No one here can ignore the calculations: every percent of solvent recovery goes straight to the bottom line — and reduces headaches over regulatory compliance.

    Real World Challenges in Quality Assurance

    There’s theory, and then there is reality on the blending line. Packaging, air control, and warehouse management can make or break an order. Moisture picks up quickly in ambient conditions, leading to caking or yellowing if handled slackly. Our analysis labs use IR and GC to verify composition, but it’s human vigilance during packing that catches 90% of trouble before it leaves the gate.

    Once in a while, we see drifting melting points and variations in color index. Experience showed us that the best results come from keeping a tight hold over temperature during storage and transport. Some manufacturers cut corners here, leading to unpredictable batches that upset downstream processors. Rather than relying on after-the-fact blending, we focus on pushing repeatable process control at the primary synthesis step, not simply batch testing after production.

    Differences from Other Lactones and Similar Intermediates

    We often field questions about differences between 2-Coumaranone and other lactones, especially gamma-butyrolactone or delta-valerolactone. Each shares some structural similarities but brings its own quirks in reactivity and final product attributes. For instance, gamma-butyrolactone is more common as a solvent and intermediate in pharmaceuticals but offers less utility in industrial resins or rubber than 2-Coumaranone. Meanwhile, delta-valerolactone works in specialty polymers but can fall short on physical property modification in larger-scale rubber compounding. Our process lines make these distinctions clear because the handling and purification steps differ; what works for a smaller lactone does not always translate at scale.

    Some producers substitute coumarin or phenolic intermediates, assuming close performance. Years of working alongside downstream users taught us that these substitutes rarely meet the same performance criteria. 2-Coumaranone’s specific ring structure grants polymers and resins a distinct toughness and gloss, difficult to replicate with alternate chemistry. In heat-seal adhesive applications especially, non-coumaranone formulations tend to give inconsistent tack and aging properties.

    User Feedback and Continual Adjustment

    Relying on direct user feedback guided many process changes. Tire customers noticed initial blends performed unevenly in high-humidity storage, prompting us to adjust not only our drying protocols but also how we line storage bins. Bookbinding customers commented on occasional stringing during hot-melt application, leading us to tighten particle size distribution and further screen raw inputs. We learned to keep an open ear to every stage of the supply chain, because the plant floor uncovers problems that the development lab or management suite often overlook.

    Customers in coatings and cast resins focus more on color and clarity. These users motivated us to fine-tune purification — extra steps in distillation and filtration, longer holding times for crystallization. In these cases, the effort paid off in brighter, more stable films that held up better under sunlight or harsh solvents. We keep regular archive samples so that if a user ever flags trouble, we can go back and pinpoint changes that caused it.

    Sustainability Concerns and Green Chemistry Approaches

    More producers in every sector ask about sustainability and process transparency. Our own plant feels growing pressure for reduced waste, less energy input, and safer handling. We moved to lower-emission reaction systems and pushed heat exchangers and condensers to cut fugitive losses. Solvent management, once an afterthought, became central: every recycled liter cuts both cost and environmental impact. Some steps in our process still need improvement, but each cycle through the system teaches us how to minimize loss and maximize recovery. Water use also draws attention. Developing closed-loop wash water systems and monitoring discharge streams became second nature for our techs, given upcoming local regulations.

    Choices about raw material sourcing also shifted. Sourcing phenol from suppliers who can track and certify their input streams builds confidence along the entire supply chain. Each link has to withstand questions from end customers and regulators. Our regular audit teams visit upstream partners, dig into process records, and check compliance — not to win green labels, but to control the variables that land on our own doorstep if upstream quality drops.

    Worker Safety and Practical Handling Insights

    On the ground, 2-Coumaranone does not handle like simpler solvents or polymer intermediates. Its powder can dust in dry conditions, requiring both adequate fume handling and worker awareness. We shifted our packaging lines to prevent dust blowouts, moved to stronger seals, and upgraded local ventilation near repack zones. Transporting the compound through humid environments highlighted caking problems, so we moved rapidly to shorter transit times and desiccant packing where necessary.

    Training our people goes further than signs and manuals. We run routine hands-on sessions, making sure every operator recognizes odors, off-colors, or signs of cross-contamination. Our teams learned through tough experience that prompt bin cleaning and strict batch control are critical: cleanup costs rise fast in case of a spill or mislabel, especially when downline customers run highly sensitive equipment. Reducing errors became about nurturing a culture in the plant — not just top-down orders but real buy-in from the operators who deal daily with risk and reward.

    Adapting to Market Demands and New Applications

    We remember a time when 2-Coumaranone mostly served bulk rubber compounders. New requests now roll in from specialty adhesive makers, electronics encapsulation, and even designers of specialty films for packaging applications. These users fall outside the traditional base, pushing us to create more tailored grades, finer screens, or additional stabilization. In electronics, for instance, users demand ultra-clean grades, free from trace metals or organic residue, since even ppm-level contamination can lead to circuit failures. We invested in new filter and wash steps to answer those calls.

    Packaging trends also reshaped how we think about 2-Coumaranone. Food-safe adhesives and compliant coatings require not just technical, but regulatory validation. Our compliance teams wrestle hand-in-hand with QA to ensure analytical traceability and clean reporting — files that users and auditors welcome rather than dread. Transparency through every step of manufacturing and QA builds more trust than any simple certificate ever could.

    Summary of Key Lessons Learned in Manufacturing

    Routine QA audits taught us the biggest improvements come from tight process integration, real communication across shifts, and active troubleshooting. Static process charts only get a plant halfway there. Operators who question inconsistencies, lineworkers who flag off-spec lots, technicians who review baseline instrument data — these people drive real product reliability.

    On the production side, control over reaction temperature and isolation timing matters more than any theoretical yield calculation. Our senior chemists and engineers often catch process drift early, long before analytics might warn of out-of-spec batches. Experience in filter maintenance, dust control, and humidity management — the practical skills developed during years on the line — matter as much as advanced instrumentation. Investment in people pays back daily, ending up visible in the trust returning customers place in each shipment.

    The Road Ahead for 2-Coumaranone

    2-Coumaranone sits at the intersection of trusted applications and new directions. For many years, tire rubber, adhesives, and resin users depended on it for robust blends and lasting performance. We now face expectations for cleaner, safer, and more sustainable production — from ourselves, from our customers, from regulatory bodies, and increasingly, from the public.

    New applications emerge in each development meeting. Specialty elastomers for medical equipment, next-generation industrial coatings, and encapsulants for solar modules and batteries represent just a few areas of investigation. Achieving higher purity, tighter control, and rigorous traceability are what will open these fields. On the ground, that means more investment in purification columns, real-time monitoring systems, and skills training across all shifts.

    Supporting Our Customers Beyond the Barrel

    Real product value shows once our 2-Coumaranone leaves the plant gate and faces real-world application. Our customer support does not end with a signed delivery note. Our team partners with users on troubleshooting: from fine-tuning resin formulation, batch troubleshooting, to discussing exact process settings for adhesive turbines or rubber mixers, we stay invested in the outcomes. For some orders, joint testing and on-site visits clarify blending questions. Technical teams from both sides trade findings, adjust settings, and swap samples until the result meets each specific need.

    We keep detailed logs and production data for years. These records ground every claim we share with our partners. When challenges come — an off-smell here, a viscosity drift there — our records support investigation and solution-finding. By committing to openness, we avoid finger-pointing and blame, focusing instead on effective fixes.

    Regulatory Shifts and Material Traceability

    No material, including 2-Coumaranone, escapes the growing web of regulatory scrutiny. Our experience with evolving environmental, health, and export requirements proved one lesson: preparation and recordkeeping head off last-minute headaches. Red labels and overdue paperwork can stop containers at the dock, delay projects, or lead to costly scrapping. Our team dedicates significant time each week not just to staying up to date with rules, but to running drills and reviewing traceability from drum to lot to raw input. Our investment in ERP and lab integration grew directly out of hard lessons: lost time and credibility cost more than any new software ever could.

    In some export markets, trace metals or even trace-level aromatic content can trigger non-compliance. We adopted more robust batch testing and regular reviews of our supply chain, not simply to avoid penalties but to build relationships through reliable delivery and meeting every spec, every time. Regulatory shifts will keep coming. The stability we offer to our partners reflects consistent diligence, open records, and steady communication.

    Conclusion: The Value of Direct Manufacturing Experience

    Manufacturing 2-Coumaranone brings surprises, challenges, and new solutions every quarter. No third-party can grasp the complex day-to-day reality: changing moisture levels, raw material surprises, or shifts in customer demand. The value we supply comes from lived experience — troubleshooting synthesis lines, improving packaging, and constantly learning from the users who rely on us. Consistent support for all customers, adaptation to changing markets, and a real commitment to safety and sustainability drive improvement at every stage. It takes hands-on work and an open feedback culture, not just equipment and data, to produce the 2-Coumaranone that keeps industry moving.