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2-Chlorophenoxyacetic Acid

    • Product Name 2-Chlorophenoxyacetic Acid
    • Alias 2-CPA
    • Einecs 202-193-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    350955

    Chemical Name 2-Chlorophenoxyacetic acid
    Cas Number 1878-73-7
    Molecular Formula C8H7ClO3
    Molecular Weight 186.59 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 148-150°C
    Solubility In Water Slightly soluble
    Density 1.44 g/cm³
    Pka 3.06
    Odor Odorless

    As an accredited 2-Chlorophenoxyacetic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 25 kg package is a sealed, labeled fiber drum for 2-Chlorophenoxyacetic Acid, displaying hazard warnings and handling instructions.
    Shipping 2-Chlorophenoxyacetic Acid should be shipped in tightly sealed containers, clearly labeled, and protected from physical damage. Store and transport in a cool, dry, well-ventilated area away from incompatible substances. Comply with local, national, and international regulations for hazardous materials. Use proper personal protective equipment (PPE) when handling.
    Storage 2-Chlorophenoxyacetic acid should be stored in a tightly closed, labeled container in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers. Protect it from moisture and direct sunlight. Avoid storing near food or feed. Ensure the storage area is equipped for spill containment and is accessible only to trained personnel.
    Application of 2-Chlorophenoxyacetic Acid

    Applications of 2-Chlorophenoxyacetic Acid in Industrial Manufacturing

    2-Chlorophenoxyacetic acid serves as a critical synthetic intermediate and active ingredient in multiple industrial sectors, thanks to its selective reactivity and well-characterized properties. Our manufacturing facility supports global supply chains by providing high-purity material that integrates into advanced downstream processes. The following sections outline primary application scenarios in established industries, covering compliance systems, actual process technologies, material input ratios, and end-use product categories.

    1. Plant Growth Regulator Production for Agrochemicals

    In the agricultural chemical sector, 2-Chlorophenoxyacetic acid functions as a plant growth regulator, stimulating cell elongation, fruit setting, and promoting uniform crop maturation. Formulators incorporate it into water-dispersible formulations and controlled-release products for field application, supporting productivity of staple crops and horticultural varieties. Manufacturers manage strict input ratios in liquid blends and powder concentrates to achieve regulatory thresholds for specific crops, balancing active loadings with inert carriers for safety and efficacy.

    Industry compliance standards

    • FAO/WHO JMPR pesticide residue limits
    • EU Regulation (EC) No 1107/2009 (placing plant protection products on the market)
    • US EPA 40 CFR Part 180.260
    • China Ministry of Agriculture NY 1107-2006

    Typical usage ratio

    • 0.05–0.15% w/w in finished agrochemical formulations, with ratio adjusted according to crop type, application method, and national residue limits

    Downstream process integration

    • Material introduced in formulation tank after pre-dissolution in compatible solvent; joint blending with adjuvants and dispersants; final product passes through micronization and homogenization stages

    Final product types

    • Plant growth regulator solutions
    • Emulsifiable concentrates for foliar spray
    • Slow-release granules for soil application

    2. Key Intermediate for Pharmaceutical Synthesis

    The compound serves as a building block in the synthesis of certain pharmaceutical actives, including anti-inflammatory agents and intermediates for non-steroidal drug APIs. Our quality-controlled product is used in multi-step synthesis chains, where precise addition ensures controlled chlorination and phenoxy substitution. API manufacturers rely on traceable batch records and verified purity for continuous production runs under validated GMP workflows.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP <623> Residual Solvents Guideline
    • European Pharmacopoeia monographs for relevant APIs
    • CFDA Measures for the Administration of Drug Production

    Typical usage ratio

    • Stoichiometric ratios from 1.0 to 1.5 molar equivalents per synthesis stage, depending on target compound and process route; ratio further defined in process validation

    Downstream process integration

    • Input at first synthetic step in the reactor vessel, typically following activation or neutralization; subsequent stages include chlorination, esterification, or coupling reactions under inert conditions

    Final product types

    • Non-steroidal anti-inflammatory drug (NSAID) intermediates
    • Phenoxyacetic acid-derived drug substances
    • Custom pharmaceutical building blocks

    3. Pesticide Intermediate in Herbicide Formulations

    2-Chlorophenoxyacetic acid acts as a core intermediate for synthesizing selective herbicides, especially for broadleaf weed control in cereals and rice. Downstream producers convert it via etherification or condensation with amines, yielding products with enhanced environmental profiles. Input ratios are process-dependent, closely monitored to meet stringent active content and impurity profile limits laid out by global agrochemical regulations.

    Industry compliance standards

    • Global Crop Protection Organization (GCP) technical standards
    • REACH Regulation (EC) No 1907/2006 registration for intermediates
    • ISO 9001:2015 for product quality consistency
    • Brazil ANVISA pesticide import requirements

    Typical usage ratio

    • 0.1–0.5 molar equivalents, adjusted per transformation route (e.g., etherification with dimethylamine vs. alkylation for proprietary actives)

    Downstream process integration

    • Introduced directly into reaction vessels during stepwise synthesis; followed by neutralization, purification, and concentration; in-process QC ensures conversion rate and by-product minimization

    Final product types

    • Phenoxy herbicide active ingredients
    • Chlorinated auxin derivatives for rice paddy management
    • Custom pre-mix concentrated herbicides

    4. Synthesis Intermediate for Specialty Dyes and Pigments

    The molecule enables downstream producers to introduce halogenated and ether functionalities in specialty dye intermediates. It serves as a starting material for azo and anthraquinone systems where chlorinated side groups impart lightfastness and chemical resistance. Processes demand reliable input volumes to maintain final product color strength and reproducibility in textile, leather, and high-end printing inks.

    Industry compliance standards

    • OEKO-TEX Standard 100 for harmful substances in textile auxiliaries
    • EN 71-3 for migration of elements in toy and ink applications
    • ISO 9001:2015 for dyes and pigment manufacturing
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals)

    Typical usage ratio

    • 0.07–0.2 molar equivalents, set by the target dye structure and desired chlorination extent; ratio varies to manage shade intensity and process efficiency

    Downstream process integration

    • Charged at the diazotization or coupling stage of dye synthesis; typically dissolved in a buffered system to control pH and reaction kinetics; post-reaction purification follows precipitation or crystallization

    Final product types

    • Chlorophenoxy-substituted azo dyes
    • Halogenated pigment intermediates for inkjet formulations
    • High-performance acid and reactive dyes for textiles

    5. Starting Material in Organic Synthesis for Aromatic Esters and Plasticizers

    This raw material supports the manufacture of aromatic esters and specialty plasticizers used in high-value polymer compounding. Chemical processors employ it as an acyl donor or aromatic ring modifier, targeting applications in wire coating, film lamination, and flexible packaging. Plant engineers calibrate feed quantities to deliver batch-to-batch consistency and ensure full downstream reactivity, matching end-use mechanical property requirements.

    Industry compliance standards

    • FDA 21 CFR Parts 175–178 for indirect food contact substances
    • EU Regulation (EC) No 10/2011 on plastic food contact materials
    • ISO 14001:2015 for environmental management at production sites
    • Japan Food Sanitation Act for additives in packaging

    Typical usage ratio

    • 0.2–0.8 weight equivalents in esterification reactions, set according to target molecular weight and mechanical characteristics of finished plasticizer

    Downstream process integration

    • Charged with alcohol or polyol reagents in reaction kettles, often with acid catalysts under controlled temperatures; product isolation by distillation or extraction prior to compounding into base resins

    Final product types

    • Aromatic ester plasticizers for PVC and synthetic rubbers
    • Specialty additives for heat-sensitive polymer blends
    • Precursor compounds for wire and cable insulation formulations

    6. Base Compound in Laboratory Reagents for Analytical Chemistry

    Research and QA/QC laboratories utilize 2-Chlorophenoxyacetic acid as a calibration and derivatization reagent in chromatographic and spectroscopic analysis. Its stable structure and known impurity profile support use in trace analysis of environmental and residue samples. Laboratories apply precise input quantities, referencing international method protocols for accuracy and reproducibility across testing batches.

    Industry compliance standards

    • ISO/IEC 17025 for calibration laboratories
    • AOAC International Official Methods
    • US EPA SW-846 for environmental analysis
    • GLP (Good Laboratory Practice) guidelines

    Typical usage ratio

    • 2–20 mg/L standard calibrant concentration for HPLC/GC analysis, with dilution adjusted for instrument sensitivity and detection limits

    Downstream process integration

    • Weighing into solvent matrix for preparation of external calibration standards; sometimes derivatized in situ for enhanced detectability; used as spiking material in quality control samples

    Final product types

    • Certified reference materials
    • Chromatography test kits
    • Laboratory reagent solutions for environmental monitoring
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    Certification & Compliance
    More Introduction

    Introducing 2-Chlorophenoxyacetic Acid: Practical Insights from a Chemical Manufacturer

    Direct from Our Production Floor: What Sets Our 2-Chlorophenoxyacetic Acid Apart

    Every batch of 2-Chlorophenoxyacetic Acid leaving our plant carries years of hands-on experience in precision synthesis and a deep understanding of client needs from across the globe. We manufacture this specific phenoxyacetic acid derivative in our own reactors, under strict protocols that we have refined with real-world feedback from our agricultural partners. It is known throughout the industry as a reliable plant growth regulator, particularly favored for its performance in fruit and vegetable crops.

    Our focus has never been just about offering another chemical option. As a manufacturer who deals with the daily pressure to meet strict residue limits and secure regulatory compliance, I've seen what matters most to growers and formulators: consistency, solubility, and predictable response in the field. This compound’s molecular signature, with a chlorine atom at the ortho position, gives it a unique position among phenoxy herbicides and plant growth stimulants. That single chlorine switch alters its physiological effects and sets it apart from 2,4-D and other phenoxy analogues.

    Chemical Profile and Specifications: No-Nonsense Detail

    We standardize our 2-Chlorophenoxyacetic Acid at a minimum purity of 98% by HPLC, as that purity level delivers the best balance between cost and biological activity for field applications. Having worked with formulations where a lower-purity product gummed up mixing tanks or led to unreliable foliar absorption, I can’t overstate the importance of minimizing inert content. Our technical team checks for melting point (105-107°C) and clarity after dissolution, since even a slight departure can signal contaminants that may create new crop injury risks or blunt the growth response.

    The powder appears off-white, though slight color differences can show up between production runs due to trace moisture or variations in the dried product. We pack the product to control caking and water absorption, because any moisture pickup during storage knocks down flowability and can mess with pre-mix solutions. Granular options exist for automated spreading, but most buyers take the fine crystalline grade because it dissolves fast—critical for rapid batch-mixing in sprayer setups or fertilizer factories.

    Applications that Validate Its Value

    Most of our output goes into agriculture and horticulture, and I've seen the shift in both crop protection and crop enhancement markets as customers recognize what this molecule can deliver at field level. Citrus growers use it to prevent premature fruit drop. Tomato and bean farmers rely on its rooting effect in transplant shock. In greenhouses, it serves as a cost-effective replacement in hormone blends once dominated by natural auxins, which are both fickle to procure and break down too quickly. We run side-by-side field trials with agronomists and major farm co-ops, tracking yield and visual response, and those hard acre results speak louder than any generic claim.

    Outside the farm, this chemical still finds niche utility. A handful of our industrial clients use it in labs for custom organic syntheses—its structure slots neatly into more complex molecules where selective aromatic substitution is needed. The demand there may be small in volume, but it speaks to robust chemistry that can stand up to more than just field use.

    Key Differences versus Other Phenoxy Compounds

    Comparisons usually start with 2,4-D, since that compound is everywhere you look in the world of plant hormones and weed control. 2-Chlorophenoxyacetic Acid carries a single chlorine, not two. This nuanced difference may look minor on paper, but on the ground it creates a much softer profile for certain crops—less harsh growth suppression, and a more defined rooting or fruit retention effect instead of wholesale broadleaf weed kill. Many of our long-term clients switched to us after bad experiences with 2,4-D drift or residue problems, which our product helps avoid by offering a milder and more targeted response.

    Compared to natural plant auxins like indole-3-acetic acid, 2-Chlorophenoxyacetic Acid resists breakdown and shows real staying power in challenging light and pH conditions. You don’t see the effect vanish overnight during a cold snap. This trait helps maintain its predictability, and that’s something our customers have come to count on, especially for export crops with tight post-harvest handling schedules.

    Manufacturer’s Perspective: Production Methods and Quality Commitment

    The chemistry behind 2-Chlorophenoxyacetic Acid isn’t new, but constant pressure to improve safety, waste management, and cost keeps pushing us to upgrade how we make it. In our experience, using high-purity raw materials and closed systems matters far more than fancy-sounding tweaks. If you start with technical-grade phenol with too many offcuts, side reactions go up and you get byproducts that no amount of post-purification will fully remove.

    We use direct monochlorination under controlled temperature, then manage the acetic acid addition with real-time pH monitoring. These aren’t just bullet points—they’re hard-learned safeguards. Fail to monitor, and you end up with off-color product, reduced biological activity, or, at worst, safety incidents in the plant. Our people spot potential issues by eye and by habit, and over the years, we’ve cut batch variability down to a fraction of what the industry used to accept. That shows up in fewer customer complaints and more repeat business.

    Waste minimization also ranks high on our agenda. The old methods produced unnecessary chlorinated byproduct streams requiring expensive neutralization. We continually test reagents and recycle solvents whenever we can, not because it’s fashionable, but because it’s costly to dispose of hazardous waste, and local environmental authorities inspect our operations at regular intervals.

    Handling and Practical Advice from Years of Shipping the Product

    Having shipped thousands of tons over the years, we see where problems come up—humidity infiltration, poor sealing, temperature fluctuations during transit. We avoid thin plastic liners because, even sealed, they don’t stand up against moisture creeping in during a long ocean crossing. Double-bagging and triple-checking container seals on humid days keeps the material flowing and usable at the customer’s location. Customers who have switched to our packaging report huge reductions in caked drums and speedier batch dissolution.

    We also provide lab support for first-time users, especially those developing new blends. In some countries, local water hardness can throw off pH and affect solubility. We help troubleshoot, because if formulation fails once, confidence in the whole order can collapse. On the farm, simple practices like pre-mixing with clean water and using constant agitation during tank mixing have proved to prevent sediment and give uniform crop application. These bits of advice come directly from season-to-season conversations with growers facing real weather and equipment challenges.

    Insights on Regulatory Requirements and Environmental Pressures

    The market for 2-Chlorophenoxyacetic Acid is shaped by shifting regulations. Europe and North America constantly update residue definitions. More countries require complete traceability for every batch. We maintain detailed batch records, with full tracking from raw material source to final shipment. This isn’t just about ticking off certificates; it is about building trust through transparency. Our compliance officers routinely audit not just our own operations, but also those of upstream suppliers. That keeps contaminant risks in check before they can ever threaten the final product.

    In response to more stringent environmental policy, we have upgraded our effluent treatment and switched to lower-chloride production waste chemistries. These investments cost money, but we see returns through smoother regulatory inspections and fewer shipment delays. Countries tightening chemical residue thresholds push us to offer higher-purity versions and tighter particle size control for more precise field application.

    Feedback Loop: How Growers and Formulators Steer Our Directions

    Our most valuable feedback doesn’t come from marketing reports; it comes from clients who tell us about rainout events, failed formulations, or standout yield results. This dialogue pushes us to maintain a responsive production schedule and develop flexible order volumes for both small-batch research and full-season commercial needs. Specialty fruit growers, who face huge financial hits on crop loss, ask for smaller lot numbers with documented purity, and we cater to that through tight process batches and custom labeling.

    Bulk pesticide formulators want compatibility with other actives, so we focus on keeping certain residuals below detection thresholds to prevent tank mixing problems. Some customers, chasing new regulatory approvals or export certifications, have asked us to provide both conventional and low-residue versions of our product. Our plant can switch between these batches with comprehensive cleanouts in place to protect order integrity. Every year, this dual capability becomes more important as traceability rules tighten.

    Technical Support and New Applications

    We regularly partner with agricultural extension agents, universities, and industry research groups to field-test new application methods. Sometimes they ask for novel formulations, like slow-release granules or new surfactant blends to improve uptake. Early testing provides early warnings on outlier behavior before those new blends ever hit a real crop. We prioritize sharing negative results as openly as successes, since even bad outcomes steer our product improvement.

    More recently, we see clients experimenting with 2-Chlorophenoxyacetic Acid for tissue culture propagation in berries and ornamentals. These uses require an extremely clean product to avoid fungal or bacterial contamination. Working closely with technical teams at these nurseries, we tweaked filtration and drying protocols to hit higher sterility standards and eliminate sources of carryover.

    Worker Safety, Handling, and Local Community Impact

    Daily production brings constant focus on staff safety. We invest time training operators on PPE use and spills, and our waste air is scrubbed before release. Periodic reviews keep our team ready for both routine tasks and rare emergencies, with older hands teaching newer hires what to watch for—from early signs of dust in the air, to off-spec odor that signals a process blip. In our region, the community keeps an eye on factory activity, and we welcome audits and tours to build mutual trust. We joined several industry-academic safety outreach groups, directly supporting better regional practices. Customers and neighbors count on our plant running clean, safe, and reliably.

    Safe transport sits high on our agenda, as does honest hazard communication. Exporters can get into trouble if paperwork downplays corrosivity or dust risks. We send SDSs, not because of ticking legal boxes, but because end users need clear, accurate hazard data at hand. Over the years, we’ve fielded late-night calls from shipping companies and customs inspectors; experience teaches that being transparent upfront keeps supply lines open and protects everyone’s reputation.

    Future Trends and Ongoing Challenges

    Plant growth regulators evolve alongside broader changes in agriculture—climate stress, pressure to lower chemical loads, and tighter food chain scrutiny. Growers expect more powerful data about how each input influences profit. Our research team chases incremental advances: improvements in bioavailability, formulation stability during long shipping, and safer byproduct management.

    One major focus in our pipeline is lowering environmental load with precision blends. Customers want more effect at lower dose rates. Achieving this asks for slicker formulations: finer-milled powder dissolves faster and ensures more complete uptake, trimming overall use. Research partnerships explore using biodegradable carriers and working to push as much of the molecule as possible onto its plant target. Success here pays off twice—crop response improves, and environmental residue risk drops.

    We face challenges in developing new application technologies, such as smart sprayers using satellite and sensor feedback to dose accurately and minimize drift. Data from these trials feeds directly back into how we process and filter the finished product. If a particular sprayer system reports clogging, our quality team tweaks drying times or sieving protocols to get it right in the next run. Every tweak aims for a compound that fits modern equipment, not just old-school spray rigs.

    On the regulatory front, uncertainty remains around local registration or allowable residue limits. We put extra effort into working with local agencies and agricultural suppliers, not trying to force fit foreign documents, but adapting our product dossiers for each market based on direct feedback from regulatory chemists. This up-front work saves wasted time and frustration for both us and our clients.

    In Summary: What Trust in a Manufacturer Means

    If there’s one lesson we’ve learned, it’s that trust builds at every link in the chemical supply chain. Our 2-Chlorophenoxyacetic Acid reflects meticulous attention not just to purity, but to performance and usability in the field. Backed by thousands of tons delivered, years of open customer communication, and a long track record of regulatory compliance, we see our job as delivering not simply one more chemical, but a solution that enables sustainable crop production, research advances, and responsible manufacturing.

    For those who rely on the compound—whether for orchard fruit set, row crop rooting, tissue culture, or new discoveries—we keep a practical focus, listening and adapting our processes so that each batch fits the next challenge. In an industry where shortcutting quality may save money but wrecks results, our approach stands for direct accountability: factory-tested, field-validated, and ready for the realities of how you use it.