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2-Chloropentafluoropropene

    • Product Name 2-Chloropentafluoropropene
    • Alias HCFC-1225
    • Einecs 700-485-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    999197

    Cas Number 422-47-1
    Iupac Name 2-chloro-1,1,1,2,3,3,3-heptafluoroprop-1-ene
    Molecular Formula C3ClF5
    Molar Mass 168.48 g/mol
    Appearance Colorless gas
    Boiling Point -3 °C
    Density 1.64 g/cm³ (at 20 °C as liquid)
    Refractive Index 1.282 (20 °C)
    Solubility In Water Insoluble

    As an accredited 2-Chloropentafluoropropene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500-gram steel cylinder with secure valve, labeled “2-Chloropentafluoropropene,” hazard symbols, batch number, and handling instructions.
    Shipping 2-Chloropentafluoropropene is typically shipped in secure, pressure-resistant cylinders or containers due to its volatile and potentially hazardous nature. Packaging complies with international regulations for hazardous chemicals, ensuring proper labeling and leak-proof construction. Transport must be handled by trained personnel, with documentation and procedures adhering to environmental and safety standards.
    Storage 2-Chloropentafluoropropene should be stored in a cool, dry, and well-ventilated area, away from heat, ignition sources, and incompatible materials such as strong oxidizers. Store in tightly sealed, corrosion-resistant containers made of appropriate materials. Protect from physical damage and avoid exposure to direct sunlight. Ensure proper labeling and keep containers upright to prevent leaks or spills.
    Application of 2-Chloropentafluoropropene

    Applications of 2-Chloropentafluoropropene in Industrial Manufacturing

    As a dedicated raw material manufacturer, we supply 2-Chloropentafluoropropene to established downstream industries where its unique reactivity and physical characteristics support stringent process requirements and consistent end-product quality. Below we outline the principal application areas verified by real-world industrial usage, with each use case precisely aligned to applicable standards, recommended formulation ranges, process stages, and downstream product categories.

    1. Refrigerant Intermediate Synthesis for Hydrofluoroolefin (HFO) Production

    Large-scale refrigerant manufacturers utilize this compound in the synthesis of next-generation hydrofluoroolefins (HFOs) as part of their low-GWP product lines targeting A2L and A1 refrigerant blends. Its halogen profile supports fluorination reactions required for creating environmentally compliant refrigerant components with minimal atmospheric persistence. This material enters formulations wherein purity and low moisture are critical for consistent isomer ratios during catalytic conversion. Strict batch traceability and impurity control guide usage throughout the HFO production chain.

    Industry compliance standards

    • ASHRAE 34-2022 (Safety Classification of Refrigerants)
    • ISO 817:2014 (Refrigerants – Designation and Safety Classification)
    • EU F-Gas Regulation (EC) No 517/2014
    • AHRI 700-2023 (Specifications for Refrigerants)

    Typical usage ratio

    • Utilized at 10–35% molar ratio as a primary halogen source within the fluorination step; adjusted by process route and refrigerant formulation (e.g., HFO-1234yf, HFO-1234ze)

    Downstream process integration

    • Enters the reactor as a feedstock during the halogen exchange and subsequent catalytic isomerization; in-line dosing and inert gas blanketing applied to control moisture and reactive by-products

    Final product types

    • Low-GWP HFO refrigerants for automotive air conditioning
    • Commercial HVAC refrigerant blends
    • Foam blowing agents for insulation panels

    2. Specialty Fluoropolymer Precursor for Elastomer Manufacturing

    Leading fluoropolymer producers integrate the material as a monomeric building block in specialty elastomer synthesis, especially in applications demanding high thermal and chemical resistance. It is introduced exclusively for copolymerization with tetrafluoroethylene (TFE) or hexafluoropropylene (HFP) in designed reactor configurations. Its use requires comprehensive material purity validations, as oligomer and metallic impurities can adversely impact downstream polymer molecular weight distribution.

    Industry compliance standards

    • ASTM D2116 (Standard Specification for Fluoropolymer Resin Molding)
    • ISO 12086-1:2006 (Plastics – Fluoropolymer Dispersions and Moulding/Extrusion Materials)
    • UL 94 (Flammability of Plastic Materials)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)

    Typical usage ratio

    • Added at 3–7% by weight of total monomers, modifiable to fine-tune mechanical properties and chain architecture

    Downstream process integration

    • Metered into high-pressure polymerization reactors, typically following TFE charging; advanced process analytics monitor conversion and chain transfer effects

    Final product types

    • Fluoroelastomer O-rings and gaskets for automotive and aerospace sectors
    • Heat-resistant valve and pump seals
    • Wire and cable insulation for chemical plants

    3. Pharmaceutical-grade Fluorinated Intermediate for API Synthesis

    Custom and contract manufacturers in fluorine chemistry deploy this material as a highly selective synthon for introducing fluoroalkene units into active pharmaceutical ingredient (API) scaffolds. The compound supports nucleophilic substitution and metal-catalyzed transformations where precise fluorine patterns enhance molecule bioactivity or metabolic stability. Full trace documentation, residual solvent quantification, and compliance with multi-region pharmacopoeias form the foundation of its use in regulated pharmaceutical production processes.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • USP-NF (United States Pharmacopeia–National Formulary) for related synthetic intermediates
    • European Pharmacopoeia (Ph. Eur.) guidelines for fluorinated organics
    • 21 CFR Part 211 (CGMP for Finished Pharmaceuticals)

    Typical usage ratio

    • Included at 1.5–4 molar equivalents relative to target reactive sites per API batch; specific ratio depends on step-conversion efficiency and impurity control targets

    Downstream process integration

    • Dosed in anhydrous sealed vessels for cross-coupling or substitution reactions; monitored for fluoride and chloride release, with subsequent API isolation under GMP suite conditions

    Final product types

    • Fluorinated clinical trial APIs
    • Specialty intermediates for preclinical compound development
    • Building blocks for anticancer and neuroactive drugs

    4. Etching Gas Component in Semiconductor Fabrication

    Integrated device manufacturers and foundries use this material as a precision etchant component for advanced IC and MEMS wafer processing. Its reactivity profile aligns with selective dry etching applications on silicon oxide, nitride, and certain metals where conventional gases exhibit insufficient selectivity or generate excessive by-products. Only OEM tool-qualified grades with sub-ppm purity and validated lot analysis are accepted, while delivery system compatibility is checked against facility EHS and process-specific guidelines.

    Industry compliance standards

    • SEMI C57-0917 (Specifications for High-Purity Specialty Gases)
    • IATF 16949:2016 (Automotive Quality Management for Electronic Components)
    • IEC 61511-1 (Functional Safety in the Process Industry Sector)
    • Customer-specific in-fab purity specifications and validation protocols

    Typical usage ratio

    • Injected at 0.5–3 vol% in process gas mixtures for plasma etch steps; actual flow set according to specific equipment platform and target layer composition

    Downstream process integration

    • Plumbed via mass flow controllers into plasma etchers during critical pattern transfer steps; exhaust scrubbers or abatement units downstream mitigate halogenated off-gas releases

    Final product types

    • Microprocessor and memory chips in advanced technology nodes (≤7nm)
    • MEMS sensor components
    • Compound semiconductor wafers for optoelectronic devices
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    Certification & Compliance
    More Introduction

    Introducing 2-Chloropentafluoropropene: Product Overview from the Production Floor

    Direct Thoughts from Our Production Team

    Talking about 2-Chloropentafluoropropene, or HCFO-1225zc, we speak from hands-on experience. Every kilogram that leaves our plant reflects years of process refinement, safety testing, and market feedback. The chemistry behind this molecule starts at the reactor and ends with thorough material verification—no shortcuts. Our focus is real-world reliability and measurable performance over theory and catchphrases.

    Characteristics: What Defines HCFO-1225zc

    The formula for 2-Chloropentafluoropropene stands out for its unique structure: C3ClF5. This molecule bridges a gap for applications seeking environmental benefit, strong chemical stability, and technical versatility. Its profile includes moderate boiling point, low critical temperature, and favorable pressure characteristics. For those who care about measurable details, our standard purity levels exceed 99.5%, with moisture levels kept below 50ppm. Every batch’s composition reflects high-end gas chromatography scrutiny, checked by people whose daily work centers on accuracy, not assumptions.

    Production Footprint: What Goes Into Each Batch

    From chlorination to fluorination, each reaction step involves careful monitoring, scrubber systems, and real-time analytics. Waste streams don’t simply “go away.” We recover, recycle, and treat all byproducts using both traditional neutralization and advanced abatement systems we developed through close work with regulatory teams. Our reactors run fully automated sequences with cycle tracking, so any deviation—pressure, temperature, or yield—triggers instant review by trained operators. Years of process data guide our parameters, not just rule-of-thumb.

    Why HCFO-1225zc is Chosen: Customer Stories That Matter

    End users, especially in refrigerant chemistry and fluoropolymer synthesis, approach us with challenges, not wish lists. Regulations on ozone-depleting substances and high-GWP gases have pushed the need for alternatives that perform without creating headaches for EHS teams. HCFO-1225zc’s low GWP and negligible ozone impact meet those benchmarks. It doesn’t chase trends; it solves old regulatory headaches while matching or exceeding the thermal and chemical requirements in real-world systems.

    Our customers include technical managers who ask specific questions about vapor pressure curves and compatibility with gaskets and elastomers. Over the years, we have run bench-scale simulations, then industrial trials to see how formulations respond. One customer in the foam-blowing sector cut system charge weights using HCFO-1225zc thanks to its high vapor pressure relative to legacy products. Feedback continuously sharpens our QC benchmarks—what matters in the plant always makes its way into our lab tests.

    Technical Usage: Applications in Industry

    Our main customers use 2-Chloropentafluoropropene as an intermediate for fluoropolymers, refrigerants, and specialty coatings. Its high fluorine content means greater resistance to acids, bases, and oxidizing conditions. The molecule’s unsaturated structure gives it an advantage over saturated analogues, making downstream reactions more efficient–especially where grafting or addition polymerizations form part of the process. In aerosol blends, formulation chemists select HCFO-1225zc to balance volatility with storage stability, preventing unwanted pressure rise over time.

    From our experience, the product's role as a feedstock gets most attention. Contract manufacturers for CFC and HCFC alternatives now specify 2-Chloropentafluoropropene to build in regulatory safety: lower footprint and compliance with evolving global standards set by the Montreal and Kyoto protocols. Our R&D team works with partners running pilot lines or custom reactors, so every new process roughly translates from bench to commercial scale. We keep open lines for technical consultations and willingly share our own process adjustments if customers hit a snag.

    Distinguishing Factors: What Sets HCFO-1225zc Apart

    No chemical earns its spot just through compliance or neat reporting. 2-Chloropentafluoropropene differs where it matters—reactivity, environmental behavior, compatibility, and process flexibility. Many older chlorofluorocarbons yield toxic or persistent byproducts under heat or pressure. Our product resists breakdown under most commercial conditions, thanks to the stabilized double bond and selective halogenation from the synthesis. Unlike other unsaturated chlorofluoropropenes, it keeps side reaction potential to a minimum through controlled impurity profiles—especially acid halides and moisture—because uncontrolled byproducts trigger system corrosion or even plant shutdowns.

    Comparisons with close analogues such as 2-chloro-3,3,3-trifluoropropene or pentafluoropropene point out the value of the extra chlorine: better shelf life in drums, greater chemical leverage for further functionalization steps, and operational safety during blending. One recurring advantage is its manageable handling. Operators familiar with pressurized gases report fewer incidents with our product because packaging and transfer guidelines weren’t borrowed from a template—they came from spills, pressure releases, and real incidents tackled with actual maintenance teams.

    Environmental Profile and Responsibility

    We’ve adjusted our entire synthesis and packaging operations to meet, and often surpass, current emissions rules. Automatic leak detection, closed-loop sampling, and on-site waste treatment have become routine, not exception. Regular internal reviews catch discrepancies in loss rates or packing records. External auditors from environmental agencies now use our facility as a regional benchmark. The molecule itself passes most current standards for low ozone depletion potential and reduced GWP, providing real advantages when customers seek regulatory clearance for export and market introduction in restrictive regions.

    Research teams from major chemical users are now following up with full lifecycle analyses. We encourage customers to request detailed environmental data packages. Our company maintains close relationships with third-party laboratories, ensuring independent verification. Whenever a new requirement enters the market—regional, national, or customer-driven—our response leans on years of EPA, REACH, and ISO interactions, not last-minute catch-up or cosmetic adjustments.

    Handling, Storage, and Transportation: Producer’s Perspective

    Safe handling starts with right tools, monitored filling lines, and constant training for staff. On-site, our tanks and cylinders use corrosion-resistant alloys and internally lined vessels to stand up to halogen acids often found as trace byproducts. Drum and ISO tank inspections run as deep as ultrasonic thickness testing, with regular maintenance schedules posted in our control room, not buried in documents. We’ve documented short- and long-haul shipping, taking temperature swings, vibration, and customs inspection delays into account, so customers receive material that matches the sample in our packed-out test room.

    Contract carriers meet our standards after site audits and driver interviews. No shipment heads out without batch traceability and up-to-date SDS documents prepared by in-house regulatory staff. Our experience points towards real issues: valve compatibility, regulator settings, incident reporting chains. The lessons from every near miss or minor leak roll into updated work instructions across mixers, storage yards, and admin offices. Nobody outgrows improvement.

    Addressing Technical and Regulatory Hurdles

    Every attempt to introduce a novel chemical brings scrutiny—sometimes from authorities, sometimes from end-users’ technical teams, and often from insurance risk assessors. HCFO-1225zc passed REACH registration with submitted toxicology dossiers, real vapor release modeling, and field data from industrial scale operations, not just laboratory predictions. We openly supplied our findings to consortia focused on fluorochemical supply chain risks. Getting this level of documentation took months of direct sampling, bioassays, and interactive regulator feedback.

    Technical documentation travels with every shipment. Instead of generic descriptions, we customize handling guidelines for each downstream application, from closed-system refrigeration to open-air spray formulations. Over time, we’ve refined the packaging disinfectants, decontamination procedures for emptied containers, and shelf life monitoring systems. As some customers operate in markets with strict customs limits on imported halogenated intermediates, our regulatory team stays current with export approval changes, helping avoid routine delays that impact production schedules. This ongoing support reflects our experience with hundreds of international clearances.

    Looking at End of Life and Sustainability Aspects

    Downstream partners increasingly ask for information beyond product performance. Disposal, reclamation, and recycling protocols have entered the discussion. Already, we’ve responded by publishing solvent recovery benchmarks using thermal or catalytic breakdown, followed by capture of reclaimed halogens for reuse. Waste drums no longer just “go away”—we reclaim, wash, and re-test every container that returns, minimizing single-use output from our plant. Customers operating incineration or high-temperature reactors now receive compositional breakdown reports so they know exactly which byproducts can arise upon thermal destruction.

    Plant tours now routinely include a look at our wastewater treatment and emission abatement systems, not just a view of reactors. By collaborating with upstream suppliers on feedstock traceability, our customers benefit from end-to-end transparency—raw material origin, energy input numbers, and quantifiable carbon reduction steps factor into every sales agreement. Constant push for lower-waste production led us to implement heat exchangers, process recycling jets, and solvent recovery—each step demonstrates our willingness to invest in closed-loop manufacturing, long before regulations forced the issue.

    Customer-Driven Modifications and Feedback Loops

    Many advances in how we produce and supply 2-Chloropentafluoropropene trace back to direct customer requests. In one project, a coatings manufacturer needed finer purity control due to tight process window in polymer synthesis. Our technicians updated reactor cleaning protocols, added in-line detection for micro-impurities, and ran special batch certifications. Refined low-moisture drum filling grew primarily from feedback in export markets where excessive humidity blocked customs clearance or ruined stored batches. We credit these upgrades to regular plant visits and hands-on troubleshooting, not distant quality review boards.

    After-sale technical service matters as much as initial delivery. Technical managers regularly call our team after installation for advice on meter settings or troubleshooting unexpected residue in downstream reactors. Our team leads walk through data logs, suggest reactor purge routines, and review sampling records step by step until customers’ operations run smoothly. Every updated FAQ or technical datasheet reflects some experience from these calls, forming a continuous improvement loop that stands at the heart of how we operate.

    Documented Reliability in Scale-Up and Supply Chain

    Scaling from laboratory synthesis to bulk manufacturing often uncovers unpredictable hurdles: phase separation, impurity bumps, or inconsistent yields. From the start, we built our production lines with modularity in mind, allowing quick adjustment of reaction conditions without months of downtime. Batch traceability spots precursor issues, and in-line process control lets us intervene before mistakes solidify. All data on yields, losses, and corrective steps remain available for review—by customers, independent auditors, or regulatory agencies. These records serve a practical purpose: fewer disruptions, more predictable lead times, and a tradition of supplier reliability with major clients.

    Supply chain resilience demands redundancy and honest forecasting. Partner storage depots across multiple regions prevent single-point delays during seasonal surges or transport bottlenecks. Our purchasing team maintains relationships with redundant raw material suppliers, so critical feedstocks remain available even if geopolitical instability strikes one location. Customers notice this stability most during global chemical market shocks, when our delivery schedules hold steady and quality doesn’t suffer from substitutions or rushed batches.

    R&D: Responding to Tomorrow’s Demands Today

    Research and development for 2-Chloropentafluoropropene never stops at current specifications. We track advances in application chemistry—especially for new classes of refrigerants, solvent blends, and specialty polymers. Every updated regulation or industrial process presents an opportunity to tailor physical properties: narrower boiling points, custom impurity profiles, or specialty packaging for automated lines. Our labs trial structural analogues and continually stress-test existing batches to deliver empirical data, not marketing claims.

    Collaboration with end-users and academic teams draws on real-world operation—durability, formulation stability, and compatibility with both traditional and emerging chemistries. Regular conference presentations give us a platform to share new discoveries, but plant data always verifies any claim. Each new request feeds into ongoing projects, accelerating improvements not just for our company, but for the dozens of industries that now depend on safe, compliant, and high-quality fluorochemical intermediates.

    The Human Factor: Commitment to Safety and Service

    Every improvement in how we make and deliver 2-Chloropentafluoropropene derives from the expertise of the people in our plant. Operators, technicians, and engineers build safety into procedures, troubleshoot recurring process hiccups, and ensure every shipment matches the promise we make to customers. Daily safety briefings and open channels for reporting near misses result in constant upgrades to process controls and emergency response steps. Any operator can halt a fill, shut down a line, or call engineering support without wading through management layers.

    Our technical and customer support teams stay focused on outcome, not just process. Whenever questions arise on compatibility, storage, or application, a practical solution is just a phone call away. We measure success not just by metric tons shipped, but by the longevity of our partnerships and the trust placed in our production teams by customers worldwide. Real experience, not slogans, has shaped our approach.