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HS Code |
857392 |
| Chemicalname | 2-Chlorodibenz[B,F][1,4]Oxazepin-11(10H)-One |
| Casnumber | 56934-87-1 |
| Molecularformula | C14H8ClNO2 |
| Molecularweight | 257.67 g/mol |
| Appearance | Off-white to light yellow solid |
| Meltingpoint | 220-224 °C |
| Solubility | Slightly soluble in organic solvents |
| Purity | Typically ≥98% |
| Storagetemperature | Room temperature, dry and dark conditions |
| Smiles | Clc1ccc2C(=O)Nc3ccccc3Oc2c1 |
| Inchi | InChI=1S/C14H8ClNO2/c15-9-4-2-1-3-8-12-10(5-6-13(17)16-12)18-14(8)7-9/h1-7H,(H,16,17) |
As an accredited 2-Chlorodibenz[B,F][1,4]Oxazepin-11(10H)-One factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, labeled with hazard symbols, secure screw cap, 5 grams, chemical name, CAS number, supplier details, and expiry date. |
| Shipping | 2-Chlorodibenz[B,F][1,4]Oxazepin-11(10H)-One is shipped in accordance with all relevant chemical shipping regulations. It is securely packaged in sealed containers to prevent leakage or contamination, labelled with hazard information, and typically dispatched via ground courier or specialized chemical carriers, ensuring safe and compliant delivery to the destination. |
| Storage | 2-Chlorodibenz[B,F][1,4]oxazepin-11(10H)-one should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Avoid exposure to moisture and direct sunlight. Use an appropriate chemical storage cabinet, and ensure all local regulations and safety guidelines for hazardous chemicals are followed. |
Applications of 2-Chlorodibenz[B,F][1,4]Oxazepin-11(10H)-One in Industrial Manufacturing2-Chlorodibenz[B,F][1,4]Oxazepin-11(10H)-One, an advanced heterocyclic intermediate, addresses critical needs in regulated downstream sectors requiring high-purity chemical scaffolds. Manufactured to support rigorous industry protocols, it provides reliable performance in pharmaceutical synthesis, specialty agrochemicals, high-grade polymer modification, and advanced material science. As the original manufacturer, we supply this compound to meet the demands of complex formulation environments and stringent compliance mandates. 1. Central Nervous System Active Pharmaceutical Ingredients (APIs) SynthesisThis compound serves as a core scaffold in the synthesis of tricyclic and tetracyclic central nervous system (CNS) active pharmaceutical agents, especially atypical antipsychotics and antidepressants. Synthetic routes typically involve substituted oxazepines; the chlorinated moiety facilitates site-selective functionalization. In pharmaceutical factories, it enters as a key intermediate during the multi-step reaction sequence and requires careful QA for impurity control. Chemists adjust its dosage relevant to batch size, downstream amidation or halide exchange, and target structure. Industry compliance standards
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2. Specialty Crop Protection ChemistryAgricultural technology companies utilize this precursor to construct selective herbicides and growth regulators. It acts as a key heterocycle in synthesis lines specializing in field-tested molecules with high specificity and low environmental residue. Downstream, formulators integrate it during controlled step reactions, linking it with other active moieties for structure–activity optimization. All downstream use undergoes multi-stage stewardship and product registration for market entry. Industry compliance standards
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3. High-Performance Engineering Polymer ModificationPolymer manufacturers leverage this compound as a structural modifier to enhance heat and chemical resistance in high-end resins, particularly for electronic encapsulants and automotive components. Its integration occurs during the co-polymerization or post-polymer chain extension step. Control of the feeding protocol and reaction temperature determines its grafting efficiency and the physiochemical stability of the resulting compound. Customers focus on meeting and validating final component compliance with critical material standards. Industry compliance standards
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4. Functional Materials for Organic ElectronicsThis heterocycle enters organic electronics workflows as a building block in synthesis of active layers for field-effect transistors, OLED emitters, and advanced sensors. Materials science labs and specialty manufacturers rely on its electron-withdrawing properties to modify conjugated systems. Introduction occurs during controlled coupling or cyclization, affecting device mobility, wavelength specificity, and operational lifetime. Each production batch must satisfy trace impurity limits critical in electronics, with QC run against international electronics material standards. Industry compliance standards
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Every step on the shop floor reflects years of hands-on work with heterocyclic chemistry. Workers in our facility do not just oversee sophisticated synthesis; they come to know each batch by sight, smell, and response to process variables. The journey that brought 2-ChlorodibenzB,F1,4Oxazepin-1110H-One to commercial scale came out of real challenges from bench to reactor, including purification bottlenecks and yields that only careful adjustment of temperature, solvents, and reagent quality could fix.
This molecule, part of the oxazepine family, stands apart in our product line. Our technical team faces its quirks daily. Direct chlorination on the dibenzoxazepinone structure brings a notorious risk of unwanted byproduct formation if the reaction mixture tips even slightly out of balance. Monitoring by in-house analytical chemists catches tiny changes at each stage. Our attention extends beyond paperwork, into direct, eyes-on supervision at every point that matters.
Years of production teach us that those using 2-ChlorodibenzB,F1,4Oxazepin-1110H-One want purity across all aspects, not just by HPLC or NMR. Lab analysis shows actual, lot-to-lot consistency, but so do the feel and behavior in downstream processes—no grainy residue, no unexpected shift in melting range, no drift in reactivity. Exact details on melting point, density, and solubility aren’t just lines in a reference table, but frequent conversation topics on our plant floor.
Consistent, pale off-white crystals with minimal dust content show up in every order we ship because those are the physical traits that keep downstream synthesis clean and trouble-free. The finer the particle, the more prone it becomes to clumping or forming electrostatic charges, so we have developed careful drying and sieving steps to avoid these annoyances. Packaging staff use polyethylene liners and inert gas purges based on past lessons, from both near-miss contamination events and customer feedback. If a user requests unusually high-purity material, our team adjusts solvent washes and recrystallization protocols rather than sending a stock lot.
Chemists familiar with dibenzoxazepines quickly notice where the 2-chloro derivative diverges. Our familiarity with the synthetic differences pays off for those scaling up or developing modified analogs. The introduction of chlorine at the 2-position pulls electron density away from the benzene ring, creating a different reactivity profile on that position, particularly when customer teams apply further functionalization after receipt.
Users working with dibenzoxazepinones lacking the chlorine group often see differences in product reactivity at position 2; this derivative opens up unique coupling and derivatization routes that aren’t available with the non-chlorinated core. In pharmaceutical intermediate work, the halogen atom not only alters chemical reactivity, but the physical characteristics during solid-state handling. Our operators routinely notice how the chloro group subtly changes melting behavior and solvent affinities, which can catch unprepared chemists off guard.
Older analogs may carry a reputation for incompatibility in some routes due to insolubility or difficult workup procedures. Our product offers a cleaner extraction and drying protocol, as repeated hands-on experience shows that it stays stable in standard organic solvents without releasing challenging byproducts. Routine sampling and real-time feedback have led us to optimize both our process and packaging to favor bench stability and safe, accurate transfer within the lab.
Chemists in industrial settings use theoretical yields and purity goals as a starting point. Real life often delivers a less forgiving scenario. Over the years, our process control team engineered reaction vessels with carefully matched agitation and reflux rates because small shifts in temperature or pH quickly drop the yield and quality. Our workers on the night shift can recall the distinctive odor when the solvent system veers a little too acidic, and they catch those changes long before any instrument does. Practical hands and trained eyes form the backbone of our operation.
Environmental controls matter, too. 2-chloro derivatives show sensitivity to long exposure to high humidity. Early on, uncontrolled warehouse conditions led to problems with caking and slow hydrolysis at the package surface. Today, all finished material moves quickly from synthesis into controlled drying rooms. Our dispatch crew checks every drum for seal integrity and records moisture readings before shipment leaves our dock.
Repackaging is avoided whenever possible. Breaking down large containers creates contamination risk and repeatedly exposes the compound to air, light, and trace water. We keep stock in single-lot, batch-tracked containers, keeping transparency for users and traceability for ourselves. Customer requests for non-standard sizes are handled by small-batch production, not by splitting big drums, which draws from our single-lot policy.
Producers of pharmaceutical intermediates, agrochemicals, and specialty polymers reach for 2-ChlorodibenzB,F1,4Oxazepin-1110H-One because of both its reactivity and its physical tractability. We see how our compound behaves under a range of catalysis systems. Years ago, an in-plant collaboration turned up a new palladium-catalyzed coupling route that drastically improved conversion, a process now being used by several of our key synthesis partners. This became a lasting improvement for others in the field and is now built into our internal protocols and technical advisories.
Materials scientists using our product for special polymer backbones share that the product’s solubility profile creates easier mixing and cleaner extrusion. Small details like surface finish and mechanical performance at the end-user level circle back to minor tweaks we made in crystallization and particle sizing. Maintaining this feedback loop, through direct communications with R&D partners and by direct testing in our labs, helps us keep our process aligned with field performance.
Analytical chemists doing research into metabolic or degradation studies appreciate the compound’s consistency. We field direct calls from lab staff confronting unexpected retention times or spectral artifacts. In many cases, our batch-level recall of starting materials, storage times, and cleaning processes solves the puzzle. First-hand technical support, based on actual involvement with each production lot, remains a key reason for our long-term relationships with users.
Quality results from daily vigilance and a steady willingness to fix problems as they appear. The physical plant team documents not just clean analytical readouts, but every observation from production runs, including color shifts, flow characteristics, and crystallization texture. Our chemists trace any off-odors or off-colors back through the chain—solvents, temperature histories, aging time, and even vessel cleaning records. Facility staff adjusted standard operating procedures after one batch displayed unexpected beige tint, revealing a vendor’s batch of solvent with contaminants previously unseen by outside labs.
No two batches behave identically. Chemists in our team track every variation, no matter how minor, using both standard analytical tools and non-standard approaches. Observations from the filtration line—pressure build-up, cake compaction, clarity of mother liquor—are added to our internal database for future investigation. Regular, internal round-table reviews with QC, production, and logistics staff cross-examine all deviations. These stand-up meetings shape practical solutions, not just corrective paperwork, and actively inform operational tweaks.
Research groups and industry operators develop new molecules using our 2-ChlorodibenzB,F1,4Oxazepin-1110H-One as a building block. Knowledge flows in both directions. Problems encountered in scale-up, mechanisms and byproduct profiles, and separation challenges frequently come back to us, shaping minor improvements in how we approach subsequent production runs.
Our technical support line does not just distribute certificates and data sheets. Chemists in actual lab work listen to details of reactivity, batch history, and downstream troubleshooting. Many times, down-to-earth discussions with users have led us to adjust parameters such as extended drying times, modified bulk packaging, or replacement of a specific solvent grade, avoiding pitfalls we see others run into. Field knowledge, gained by tight collaboration and mutual problem-solving, steers our ongoing improvements.
Over decades, the demand for specialty building blocks rises and falls with shifts in pharmaceutical research, regulations, and economic trends. Gaps in supply chains have taught us the value of robust, local raw material sourcing. Forced downtimes, once caused by vendor changes or poor-quality starting materials, are now largely avoided. The purchasing team builds long-term relationships directly with chemical suppliers, not through trading houses.
We saw market shortages ripple through the industry during worldwide disruptions. Those who counted on spot-buy shipments from brokers found themselves with untested or poorly documented lots. We avoided such pitfalls by holding safety inventory, keeping batch-level controls, and maintaining a threshold of overproduction. Procurement and logistics staff receive ongoing feedback from the front lines—demand projections updated weekly, raw material lot checks, and plant tours by partners, not just auditors. This real-world exposure narrows the gap between planning and execution.
Sustainability and chemical handling are not abstract policies. Workers who manage 2-ChlorodibenzB,F1,4Oxazepin-1110H-One in the plant want to avoid exposure to fine dusts, splashes, and volatile residues. Direct input from the plant floor led us to invest in closed-transfer systems and automated blending, reducing airborne particulates and manual handling. Regular air quality and residue monitoring are seen as routine protection, not just regulatory requirements.
Environmental regulations grow stricter by the year. By mapping our process emissions and waste streams, we shifted from high-effluent wash-down protocols to closed-loop solvent reclamation for our most commonly used purification steps. Waste aqueous streams are neutralized on-site with careful, logged addition and off-gassing controls, overseen by our own team members who have developed their skills through firsthand work.
Customers bringing our material into new markets rely on honest transparency regarding content and traceability, not just regulatory-compliant paperwork. We support their audits with full access to historical lot records, environmental data, and staff interviews, backing up any data we provide with direct, original documentation.
Real change in chemical manufacturing comes from an openness to evolve alongside partners—researchers, buyers, end-use operators. Each request or complaint that crosses our desk becomes a learning point. By keeping ears open to feedback and eyes on the daily realities of production, we adapt our routines quickly. This direct, two-way engagement with the wider scientific community guides every upgrade in our production line, analytical procedures, and even daily maintenance.
Over time, collaboration shapes more than just the technical attributes of 2-ChlorodibenzB,F1,4Oxazepin-1110H-One; it creates long-term commitment to safety, transparency, and the real-world viability of our product. Our team continues to push for better, safer, and more reliable delivery, grounded in years of cumulative expertise at every stage from molecule to finished drum.