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HS Code |
345280 |
| Cas Number | 87-63-8 |
| Molecular Formula | C8H10ClN |
| Molecular Weight | 155.63 |
| Iupac Name | 2-chloro-N,N-dimethylaniline |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 234-236°C |
| Density | 1.092 g/cm3 at 25°C |
| Flash Point | 104°C |
| Solubility In Water | Insoluble |
| Refractive Index | 1.558 |
| Vapor Pressure | 0.09 mmHg at 25°C |
| Smiles | CN(C)C1=CC=CC=C1Cl |
| Synonyms | 2-Chloro-N,N-dimethylaniline; 2-Chloro-N,N-dimethylbenzenamine |
| Ec Number | 201-764-9 |
As an accredited 2-Chloro-N,N-Dimethylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams, labeled "2-Chloro-N,N-Dimethylaniline," with hazard symbols, chemical formula, and safety instructions. |
| Shipping | 2-Chloro-N,N-Dimethylaniline is shipped in tightly sealed, chemical-resistant containers to prevent leaks and exposure. Packages are clearly labeled for hazardous content and handled according to regulatory guidelines. Transport is typically by ground or air, adhering to relevant safety standards (e.g., DOT, IATA), with documentation to ensure proper handling and traceability. |
| Storage | 2-Chloro-N,N-Dimethylaniline should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Keep the container protected from direct sunlight and moisture. Use in a chemical fume hood. Ensure appropriate labeling and store away from heat sources and ignition points to prevent hazardous reactions. |
Applications of 2-Chloro-N,N-Dimethylaniline in Industrial ManufacturingAs an established producer specializing in aromatic amine derivatives, we supply 2-Chloro-N,N-Dimethylaniline to global manufacturers for integration into advanced chemical syntheses across dyes, agrochemicals, and pharmaceutical intermediates. The following sections provide dedicated application scenarios, each presenting real-use compliance frameworks, recommended technical usage ratios from plant-level practices, detailed process connection points, and resulting downstream product categories. 1. Intermediate for Cationic Dyes Synthesis2-Chloro-N,N-Dimethylaniline plays a key role as a precursor in the synthesis of cationic (basic) dyes, particularly for coloring polyacrylonitrile fibers. It introduces the required electron-donating and electron-withdrawing balance during the condensation and quaternization phases, impacting both color strength and fastness. Users often select it for trityl dye compounds where specific chromophore development and shade precision are demanded in textile and fiber coloring operations. Industry compliance standards
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2. Agrochemical Intermediate for Herbicide SynthesisIn high-volume agrochemical sectors, this chemical serves as an essential building block for synthesizing certain phenylurea and anilide herbicides. Producers rely on its chloro group for electrophilic aromatic substitution, allowing precise linkage to form herbicidal backbones. Large-scale agro plants utilize it to achieve required purity that prevents active ingredient degradation in field formulations. Industry compliance standards
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3. API Intermediate in Antihistamine ManufacturingPharmaceutical manufacturers apply this raw material during the targeted synthesis of certain antihistamine drug intermediates. Its dimethylamino function allows selective introduction of substituents, crucial for subsequent cyclization and esterification in producing non-sedative H1 receptor antagonists. Strict impurity control during these steps ensures downstream compliance with global monographs. Industry compliance standards
Typical usage ratio
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4. Precursor for Specialty Agrochemical Color MarkersBeyond active agro ingredients, certain agrochemical formulators use this compound to create marker dyes for seed coatings and pesticide formulations. It supplies a chromophore base that integrates into custom-blended, field-stable markers, supporting traceability and application verification in modern precision agriculture. This colorant use demands stability under UV and agro-formulation exposure conditions, verified through rigorous QC protocols. Industry compliance standards
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5. Intermediate for Pigment Violet 1 ProductionThis raw material is an essential starting point in synthesizing Pigment Violet 1, a triarylmethane pigment widely adopted for high-grade inks and plastics coloration. Its role centers on leading the amine condensation, ensuring final pigment particle uniformity and tinting strength. Our material meets targeted purity for multi-ton scale pigment manufacturing under continuous-flow processes. Industry compliance standards
Typical usage ratio
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For chemical manufacturers, the phrase “2-Chloro-N,N-Dimethylaniline” carries meaning beyond a chemical formula. Decades making specialty and fine chemicals for pharmaceutical, agrochemical, and color industries have taught the critical nuances in preparing aromatic amines like this one. Our facilities use well-tested methods so each consignment upholds required standards for 2-chloro-N,N-dimethylaniline, also called 2-chloro-N,N-dimethylaniline or o-chloro-N,N-dimethylaniline.
On paper, the chemical structure is simple: a dimethylaniline core with a single chlorine atom attached to the ortho position on the benzene ring. In practice, producing high-purity batches involves tight controls on reaction conditions and purification. Purity always matters; for catalytic reactions or when synthesizing advanced building blocks, small impurities can lead to off-spec results down the line. This isn’t just a matter of color or clarity. Trace byproducts might affect downstream steps, waste time, and raise production costs for end users.
Reputation as a manufacturer grows from experience and feedback. Our lots of 2-chloro-N,N-dimethylaniline regularly achieve assay values above 99 percent, as measured by gas chromatography and HPLC. We keep water content low by investing in adequate drying, whether that means precise vacuum transfer or the right drying agents. Unreacted starting material and side products, such as N-methylaniline or polychlorinated derivatives, remain below minimal thresholds.
Packaging and documentation receive the same scrutiny. Industrial clients expect consistency from drum to drum, and that’s only possible with well-maintained filling systems and integrity checks. Containers stay sealed and use materials that won’t interact with the amine or introduce contamination – plain steel drums just don’t cut it for reactive aromatic amines. Secure, inert-packaged material means no surprises when the product is opened.
Aromatic amines share certain physical and chemical behaviors, but a single change in substitution pattern brings vast differences in utility. Many clients ask how 2-chloro-N,N-dimethylaniline varies from its isomers or close cousins:
Years spent exchanging technical notes with research heads, plant engineers, and application chemists have cemented the product’s value in complex syntheses. 2-chloro-N,N-dimethylaniline often becomes a precursor in the production of azo dyes or used as a coupler in pigment manufacture. Textile dyeing remains a core field, but it’s not alone. Agrochemical intermediates sometimes use this amine structure as a base skeleton. Fine chemical companies employ it in stepwise couplings, especially where ortho-chloro substitution blocks unwanted side reactions.
Pharmaceutical development taps into this molecule's ability to introduce both nitrogen and halogen into complex scaffolds. Custom synthesis firms like working with our lots because the purity and consistency save time during scaling. We’ve heard from seasoned chemists who recount weeks saved avoiding repeated recrystallizations thanks to well-purified starting material.
We recognize the responsibility to provide actionable documentation alongside each batch: full chromatograms, impurity profiling, detailed COAs. Clients in regulated industries count on this transparency. They’ve told us that clarity up front makes for smoother audits, and cleaner validation steps.
Experience with secondary aromatic amines makes clear the need for judicious handling, not just for product longevity but also worker safety. Controlled ventilation in filling and dispensing areas, PPE requirements, and careful transfer protocols help avoid both exposure risks and off-spec material. We train our staff in the practical realities – from the best ways to keep lines dry, to methods for sampling under inert atmosphere.
Temperature and packaging translate directly to shelf life. Exposing product to humid or oxygen-rich air degrades quality faster. Over the years, we’ve found a multi-layer drum seal offers both mechanical resilience and protection from external environmental factors during global transit.
Clients sometimes ask why products from different sources don't always behave the same way in formulations. Living with the day-to-day of chemical production, we’ve seen cases where what’s on the COA doesn’t tell the whole story. Minute impurities, batch-to-batch residual moisture differences, or microtraces of catalyst can affect clarity, flow properties, or even odor, influencing downstream productivity.
Replicating fine-scale production across bigger volumes requires assay precision and honest feedback. We operate with in-house labs plus independent verification when requested, striving for both product and documentation that’s matched to the end-use task, whether that means color stability in a dye vat or maximum conversion in a pharma intermediate synthesis.
As the original manufacturer, we trace every lot of 2-chloro-N,N-dimethylaniline to its process batch. Raw material sourcing stands under strict quality checks, and our reactors run in controlled campaigns, not generic continuous processes. Both personnel and equipment history get logged, so that any process deviation can be quickly pinpointed and corrected. External auditors and multinational firms visiting our plant find open books – a necessity for confidence and accountability.
Older systems using hand-batch records sometimes let minute errors slip through. We’ve invested in digital systems that track every gram from precursor to finished drum. If a client ever needs a record of specifics, such as detailed impurity runs or handling conditions, we respond with direct documentation rather than generalizations.
International shipments add another layer of scrutiny. Customs and client site inspections often require more than just COAs. Our team provides full shipping documentation, photographic evidence of drum sealing, and, when needed, temperature-logger records to confirm consistent transit environments for sensitive cargos.
Decades supplying the same fine chemical to recurring buyers brings trust, but also a continual expectation to adapt. Input from end users guides our approach to both process optimization and new technical requirements. Small changes in application, like a shift in solvent systems or downstream catalysts, sometimes increase the need for even lower levels of residual byproducts or moisture.
Pharmaceutical and dye companies often come back, preferring to source directly from a known producer rather than risk unpredictable outcomes with resellers or generic sources. In trouble-shooting calls, our technical staff rely on real production records to address issues, rather than standard responses or unhelpful speculation. Shared history with lots helps smooth changing specifications or evolving regulatory demands.
Direct manufacturing of aromatic amines puts compliance right in the conversation. Waste minimization, solvent recycling, and emissions controls enter process planning from the outset. Our newer synthesis lines run on reduced solvent systems, both to reduce environmental impact and to cut downstream treatment costs. Corporate buyers and clients in high-regulation regions ask for evidence, and our operations provide pollutant reporting, certified disposal documentation, and real-time safety data.
We keep our staff trained in best environmental practices and maintain storage facilities that minimize risk. Audit visits are routine, not last-minute events. This transparency reassures international partners handling sensitive downstream uses.
A common challenge with 2-chloro-N,N-dimethylaniline: balancing purity, yield, and economic production rates. Cutting corners, either in raw material selection or in the post-reaction workup, can push unwanted byproducts above target limits. Experience shows that dedicated, well-trained staff catch small anomalies before they impact a batch. Investments in in-line analytics and early signal tracking have made it easier to halt and address issues well before they scale up.
Distant shipping destinations sometimes raise stability questions. In response, we conducted our own shelf-life and transport stress studies and now use double-sealed linings for oceanic shipments. For customers in warmer climates or without climate-controlled warehouses, we ship with cold packs during the hot season.
Clients deploying new analytical methods, such as advanced NMR or high-resolution GC-MS, have worked with us to cross-check purity assessment protocols. Adjusting batch reporting for these new methods helped remove discrepancies before new batches were scaled up.
Our approach draws on direct plant data and real problem-solving. Some years back, a dye company reported unpredictable yields after switching to our product from a generic source. On review, the core issue turned out not to be assay numbers, but trace catalytic metals stemming from an upstream process difference. Adjusting reactor cleaning and catalyst dosing protocols produced an order-of-magnitude drop in these residues. Our customer’s performance issues disappeared, and the same approach has helped prevent recurrences.
Pharmaceutical manufacturers have remarked on batch repeatability, especially during scale-up. More predictable results flowed from better impurity control, not just higher stated purity. Looking at impurity profiles, we continuously refine operating windows for reaction temperature, chlorination rate, and isolation time.
In the early days, downstream issues often surfaced after the fact. Current practice prioritizes active listening, shared pilot trials, and rapid feedback within a flexible manufacturing structure. As needs changed or new application requirements appeared, so did internal standards and process upgrades.
We see customer needs evolving, with more digitalization and more demanding specifications every year. Cost efficiency and environmental compliance will only matter more as regulatory controls stiffen. Our in-house R&D teams keep tuning both process chemistry and analytics so that each lot of 2-chloro-N,N-dimethylaniline sets a higher bar.
Open partnerships with clients mean ongoing sample exchange, third-party testing, and transparent reporting. More than a formula, this product’s value sits in reliable utility and straight answers. Our focus stays on actionable documentation and accountable process management – both for today’s applications and tomorrow’s challenges.
Direct manufacturing experience grounds our understanding of both the molecule and the marketplace. Responding to each new technical challenge, each adjustment in regulatory outlook, we draw on a track record built from working in the field, not from the sidelines.