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2-Chloro-N-Methylaniline

    • Product Name 2-Chloro-N-Methylaniline
    • Alias o-Chloro-N-methylaniline
    • Einecs 202-429-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    738822

    Chemicalname 2-Chloro-N-Methylaniline
    Casnumber 578-68-7
    Molecularformula C7H8ClN
    Molecularweight 141.6 g/mol
    Appearance Light yellow to brown liquid
    Boilingpoint 229-231°C
    Density 1.17 g/cm³
    Solubility Slightly soluble in water
    Flashpoint 108°C
    Refractiveindex 1.584
    Structuralformula ClC6H4N(CH3)H
    Synonyms 2-Chloro-N-methylbenzenamine
    Pubchemcid 11729

    As an accredited 2-Chloro-N-Methylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Chloro-N-Methylaniline (100g) is supplied in an amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 2-Chloro-N-Methylaniline is shipped in tightly sealed, clearly labeled containers to prevent leaks or contamination. It must be handled as a hazardous chemical, typically packed in accordance with local, national, and international regulations. The packaging safeguards against moisture, heat, and physical damage during transit, ensuring personnel safety and regulatory compliance.
    Storage 2-Chloro-N-Methylaniline should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of heat, ignition, and incompatible substances such as oxidizing agents. Protect from light and moisture. Use chemical-resistant secondary containment and ensure containers are clearly labeled. Follow local regulations and safety protocols when handling and storing this hazardous chemical.
    Application of 2-Chloro-N-Methylaniline

    Applications of 2-Chloro-N-Methylaniline in Industrial Manufacturing

    2-Chloro-N-Methylaniline serves as a key intermediate in several industrial chemical syntheses. As the original manufacturer, we deliver this material to leading companies in multiple sectors, each with strict process, compliance, and integration requirements.

    1. Agrochemical Intermediate Synthesis

    Manufacturers in the agrochemical sector use 2-Chloro-N-Methylaniline to synthesize herbicides and insecticides, specifically as an amine building block in the production of phenylurea and anilide compounds. The selection and dosing are influenced by targeted crop protection formulations, reaction yield control, and environmental safety guidelines within the production process.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical registration and evaluation
    • OECD guidelines for chemical testing of agrochemicals
    • ISO 9001:2015 certification in production quality systems
    • European Food Safety Authority (EFSA) regulations for active ingredient residual limits

    Typical usage ratio

    • 5%–15% by weight in precursor blends for substituted aniline derivatives. Adjusts according to yield targets and downstream reactivity of coupling partners.

    Downstream process integration

    • Acts as a direct reactant in amination or condensation stages of crop protection synthesis lines.
    • Introduced after halogenation or nitro reduction steps when making complex ureas or amides.
    • Feeds into enclosed reactor systems with controlled nitrogen inerting and continuous quality monitoring for impurity control.

    Final product types

    • Phenylurea-type herbicides (e.g., chlorotoluron, isoproturon)
    • Anilide-based insecticides and fungicides
    • Herbicide safeners

    2. Pharmaceutical API Intermediate Manufacturing

    API manufacturers use this material as a coupling and modification agent for various active pharmaceutical ingredient (API) intermediates, especially those within analgesic and antipyretic categories. Quality requirements focus on low-metal residue, high purity, and batch traceability, with regulatory audits at each step of multi-stage syntheses.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients (ICH Q7)
    • United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.) raw material monographs
    • FDA 21 CFR Part 211 (current Good Manufacturing Practice for Finished Pharmaceuticals)
    • ICH Q3A/B impurity control guidelines

    Typical usage ratio

    • 3%–10% based on the total weight of intermediates, depending on the specific multistep route and fixed by stoichiometry of target chemical transformations.

    Downstream process integration

    • Introduced during aromatic amination or methyl-substituted ring functionalization steps in batch reactors.
    • Requires in situ monitoring for residual levels and byproducts by HPLC or GC-MS.
    • Material often undergoes additional purification before entering final coupling or N-acylation stages.

    Final product types

    • Antipyretic and analgesic intermediates
    • Arylacetamide-based APIs
    • Other heterocyclic pharmaceutical building blocks

    3. Dye and Pigment Manufacturing

    Producers of dyes and organic pigments incorporate this raw material as a monochloro-substituted donor in azo dye syntheses and other colorant preparations for textiles and plastics. Exact dosing and processing controls address both shade reproducibility and colorfastness, with integration into sequential nitration and coupling stages under industry-specific safety regimes.

    Industry compliance standards

    • EU Regulation (EC) No 1907/2006 (REACH) for substances in textile colorants
    • Oeko-Tex Standard 100 limits for harmful chemicals in finished goods
    • ZDHC (Zero Discharge of Hazardous Chemicals) requirements
    • AFIRM Restricted Substances List (RSL) for apparel and footwear

    Typical usage ratio

    • 5%–20% based on dye mass; adjusted within process scale depending on intensity, tone requirements, and final substrate type.

    Downstream process integration

    • Enters diazotization or coupling reactors during synthesis of azo, aniline, and quinoline colorants.
    • Material added post-nitro group reduction and before final solvent extraction steps.
    • Inline color testing and HPLC analysis ensure correct intermediate formation before crystallization.

    Final product types

    • Azo and anthraquinone dyes for textiles
    • Organic pigments for engineering plastics and automotive coatings
    • Inkjet printing colorants

    4. Specialty Chemical and Polymer Additive Formulations

    Producers of specialty polymers and engineering plastics utilize 2-Chloro-N-Methylaniline to manufacture stabilizers, processing aids, and performance-improving additives. The integration process prioritizes controlled reaction environments for modified aniline derivatives, and compliance includes sector-specific raw material screening to manage residual aromatic amine levels in final products.

    Industry compliance standards

    • Global Automotive Declarable Substance List (GADSL)
    • Restriction of Hazardous Substances Directive (RoHS) for electrical and electronic equipment
    • UL 94 and ISO 1043 testing for polymer additives
    • ISO 14001:2015 for environmental management during manufacture

    Typical usage ratio

    • 2%–8% in feedstock blends for co-monomer or additive synthesis, tailored to molecular structure of final polymer formulation and customer specification sheets.

    Downstream process integration

    • Used in step-growth or chain-transfer reactions during additive precursor preparation.
    • Blended with polyol or isocyanate intermediates in resin modification before bulk polymerization.
    • QC personnel monitor aromatic amine content in real time to comply with export product safety standards.

    Final product types

    • Heat stabilizers for thermoplastics
    • Processing aids for specialty films
    • Modified engineering polymers (e.g., polyimides, polyamides)
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    Certification & Compliance
    More Introduction

    2-Chloro-N-Methylaniline: A Closer Look from the Manufacturer’s Floor

    Product Story and Industry Perspective

    Every day in our factory, shelves fill up with drums of 2-Chloro-N-Methylaniline, labeled by batch and inspected each shift. We’ve seen this compound progress from a niche intermediate to a regular fixture for formulators working on dyes, pharmaceuticals, and agrochemical projects. This growth isn’t accidental. Product makers depend on trusted quality and supply consistency, especially when their end products play vital roles in modern life. Many customers want details beyond the basics, so let’s get into what 2-Chloro-N-Methylaniline means from a producer’s viewpoint.

    Understanding 2-Chloro-N-Methylaniline: Key Features

    2-Chloro-N-Methylaniline stands as a core building block for several industrial processes. It appears as a clear to pale yellow liquid, generally stable under typical warehouse settings. Customers recognize this chemical by its CAS number 695-19-2 and its systematic name. Authentic batches meet high purity standards, typically above 99%, and our routine gas chromatography tests reflect this performance day after day.

    We manufacture at a scale that supports regional and multinational operations, running continuous reactors overseen by teams trained in both safety and technical control. From raw material feeds to the final product, the workflow focuses on traceability and contamination avoidance. High-purity 2-Chloro-N-Methylaniline reacts cleanly, which matters for downstream efficiency—an issue we hear about regularly in customer meetings.

    Chemical Properties and Behavior in Processing

    The molecular structure—an aniline core with a chloro group at the ortho position and a methyl on the nitrogen—gives 2-Chloro-N-Methylaniline a unique reactivity. This arrangement influences how it fits into synthesis routes for complex molecules. You get the best results in coupling reactions that don’t tolerate a lot of byproducts, particularly in fine chemical streams.

    Producers who switch from other substituted anilines to this grade often point to cleaner reaction profiles and easier separations. Side reactions decline when purity stays high, confirmed not just by our internal labs but also by third-party auditors and mutual customer checks. So, from our perspective, investing in the right purification steps isn’t just regulatory—it’s practical for everyone down the chain.

    Applications and Why They Matter

    2-Chloro-N-Methylaniline sees use in a mix of sectors. Most of what we make feeds into colorant producers—azo and anthraquinone dye lines, for instance—where the position and number of functional groups dictate hue and lightfastness. Customers in pigment manufacturing often call out how this compound shapes their synthetic palettes and improves color strength.

    Agrochemical innovators request this intermediate for herbicide and fungicide precursor synthesis. Reaction reliability becomes crucial during scale-up, especially where regulatory reviews require reproducible impurity profiles. That’s why we work with partners to adjust process controls specifically for their downstream risk points.

    Pharmaceutical developers cautiously source this molecule for several APIs and investigational materials. We run extra analytical checks for these buyers, who must track nitrosamine and related contaminants in accordance with current guidance. Our familiarity with ICH Q7 manufacturing standards comes straight from years of regulatory inspections—an experience that shapes every batch release.

    Model and Specification Choices

    Most orders specify a liquid form, but as the manufacturer, we sometimes tailor storage and packaging formats. We standardize on drums with UN compliance markings, lined for chemical resistance. Bulk iso-container filling remains a regular option for repeat customers, lending itself to just-in-time plant deliveries and direct pipeline unloading.

    Our published typical specifications maintain purity at or above 99%, with moisture and amine-related impurities held below 0.2%. Gas chromatography signatures serve as the main purity confirmation, backed by regular titration and spectroscopic crosschecks. Each production shift enters data directly into validated software, and deviations trigger immediate sample retesting—real production-floor routines, not marketing talk.

    End users in pharmaceuticals or high-purity dye sectors ask for extra documentation. Our in-process QC teams log every test, and we provide full traceability for each kilogram delivered. Sometimes customers compare our 2-Chloro-N-Methylaniline to samples sourced overseas and notice fewer unknowns on chromatograms, a result born out of persistent investment in analytical instrumentation instead of broad claims.

    2-Chloro-N-Methylaniline vs. Related Products

    People sometimes lump 2-Chloro-N-Methylaniline in with general chloroanilines or N-substituted anilines, but the distinction matters. Pure 2-Chloroaniline, for example, carries a higher reactivity in certain condensation and coupling steps, yet often brings more environmental and safety controls thanks to its volatility. N-Methylaniline, lacking the chloro group, doesn’t offer the selectivity and reactivity pattern needed for many colorant syntheses.

    Mixing up anilines can derail batch planning. Each substituent on the aromatic ring tweaks electronic effects and sterics—effects that plant chemists see play out when scale-up steps unexpectedly go off-spec. Over the years, formulation scientists send us feedback showing that using the wrong analog causes not just a dip in yield, but shifts in reaction kinetics that slow down overall plant throughput.

    We’ve worked alongside process R&D teams comparing 2-Chloro-N-Methylaniline to the N,N-dimethyl or di-chloro equivalents. A second methyl group or chlorine atom might look similar on paper, but practical runs show significant differences in solubility, toxicity, regulatory flags, and final product disposal. As manufacturers, our role includes highlighting these distinctions during project design meetings, sharing recent process data, and offering samples to prove claims aren’t just theoretical.

    Safety, Handling, and Reliability

    Proper handling matters here, and not just on paper. We train new operators on the particular hazards of aromatic amines, with an emphasis on spill prevention, air monitoring, and PPE use. Our storage rooms use closed-loop venting and leak detection sensors that tie into facility alarm systems—because past experiences with valve leaks have driven home that the real world rarely matches the brochure.

    We maintain safety data sheets reflecting the latest GHS updates, revising recommendations based on feedback from our shipping and logistics teams rather than using off-the-shelf documents. Discussions with downstream formulators—especially those handling food chain or pharma-intermediate applications—circle back to supplier reliability as a core concern. Customers want suppliers who act fast on deviations and who share process improvement strategies openly.

    Sustainability and Regulatory Pressures

    Chemical producers feel the regulatory landscape shifting every year. 2-Chloro-N-Methylaniline falls under scrutiny in REACH, Indian and Chinese environmental regulations, and multiple regional chemical acts. We track these changes closely and work directly with consultants to keep compliance evidence ready, not only for audits but also for real-time customer needs.

    Sustainability challenges center on effluent treatment, energy use, and byproduct minimization. We run closed-loop water systems and multi-stage air scrubbers to cut down emissions above stack limits. As new rules arrive, our process engineers iterate production schemes to boost atom efficiency and cut halogenated waste at the source.

    A decade ago, outreach about these improvements felt mostly voluntary. Now major buyers score suppliers not just by price and delivery time but by precise LCA audits and carbon figures. Brands downstream from us, keen to assure shareholders and end consumers, expect proof that upstream chemistry aligns with public commitments to greener supply chains. We share our protocols with partners willing to invest in co-optimization—real joint projects that take years, not months, but pay off in risk reduction and brand protection.

    Supporting Innovation in Downstream Fields

    The utility of 2-Chloro-N-Methylaniline grows with each new pesticide, pigment, or specialty polymer that comes to market. Our liaison staff attends technical conferences, showcases working samples, and answers questions about performance data drawn straight from the plant floor. Success stories pass between R&D teams more by word of mouth than by glossy catalogs: a new high-performance pigment line, a pharmaceutical derivative finally through pilot scale, or even a film coating that resists breakdown in harsher environments.

    Shared learning accelerates both product and process advances. Once a downstream partner flagged a troublesome synthesis step with another supplier’s lot. After running parallel trials with our 2-Chloro-N-Methylaniline, they reported increased throughput and fewer chromatographic outliers. Our technical group visited their site, traced the improvement to lot-to-lot purity consistency, and followed up by testing joint modifications to crystallization endpoints. A half-day of work saved three weeks of troubleshooting—evidence that direct manufacturer insight beats theory or broad claims.

    Facing Supply Chain Realities

    The pandemic era put chemical supply lines to the test, with raw material delays, transport hold-ups, and price swings now regular talking points. We’ve invested in local backups, buffer tank farms, and digital tracking. Our logistics crew tracks every outbound shipment using time-stamped processes, from trailer loading to customs signoff.

    Customers depend on predictability—not only purity or technical compliance, but delivery you can set a watch by. Unplanned stops or prolonged lead times mean entire production lines sit idle. That’s why we keep local buffer stocks, reroute through alternate ports, and notify buyers as soon as a disruption looms. It’s not a perfect science, but direct experience with these headaches makes us double-check projections, rather than promising the world and hoping the numbers work out.

    Longstanding customer relationships grow on transparency. Our account staff shares real capacity information—good and bad—across upcoming quarters, helping buyers plan for peak production or raw material renewal seasons. Lessons learned from previous disruptions feed into new route planning and secondary sourcing.

    Continuous Improvement and Customer Feedback

    Manufacturing high-purity intermediates like 2-Chloro-N-Methylaniline isn’t a “set and forget” affair. We regularly adjust operating parameters based on customer feedback, pilot plant results, and updated regulatory thresholds. Incoming calls from process engineers trying to fine-tune yields or meet downstream compliance targets often spark changes that ripple through our own SOPs.

    Every change runs through both in-house and independent third-party validation. Operators on the floor catch subtle trends that sometimes escape the lab, such as viscosity shifts in summer heat or odor strength during longer storage. These observations build into shared plant knowledge, reducing mishaps for future runs.

    Buyers facing tighter downstream specs—less than 0.1% unknown impurities, trace-level moisture targets—challenge us to push quality further. We don’t shy from delivering regular audit trails, providing split sample data, or troubleshooting post-delivery hiccups. Joint root-cause analyses after outlier events help teams on both sides learn for next time, profitably and safely.

    Looking Forward: The Manufacturer’s Role

    We take pride in seeing 2-Chloro-N-Methylaniline support new innovation and daily commerce alike. Our staff, spanning operations, QC, logistics, and technical services, brings years of direct handling and supplier-side troubleshooting to every batch that leaves our gates. Most of our improvements—be it tighter purity, safer handling, or more reliable supply—stem directly from frontline challenges, not distant market trends.

    In a market flooded with generic versions and traders offering uncertain reliability, our value rests on transparency, consistent quality, and technical support drawn from real-world production. Customers rightfully deserve more than a spec sheet—they gain from working with those who know the product, have navigated its challenges, and stand ready to solve new ones.

    Our approach stays rooted in the experience of daily production: continuous investment in technology, regular engagement with regulators and downstream users, and the sustained effort to raise standards across the board. For buyers pursuing robust supply and performance from their 2-Chloro-N-Methylaniline, working with a proactive manufacturer means fewer surprises and more shared success, batch after batch.