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HS Code |
390351 |
| Chemical Name | 2-Chloro-1,4-Naphthoquinone |
| Molecular Formula | C10H5ClO2 |
| Molar Mass | 192.60 g/mol |
| Cas Number | 1010-60-2 |
| Appearance | Yellow to orange crystalline powder |
| Melting Point | 110-113 °C |
| Solubility In Water | Insoluble |
| Density | 1.45 g/cm³ |
| Purity | Typically ≥98% |
| Storage Conditions | Store in a cool, dry place out of direct sunlight |
| Synonyms | 2-Chloronaphthoquinone, 2-Chloro-1,4-naphthalenedione |
| Smiles | ClC1=CC(=O)C2=CC=CC=C2C1=O |
| Inchi | InChI=1S/C10H5ClO2/c11-7-5-9(12)8-4-2-1-3-6(8)10(7)13/h1-5H |
As an accredited 2-Chloro-1,4-Naphthoquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 100g package of 2-Chloro-1,4-Naphthoquinone arrives in a tightly sealed amber glass bottle with a clear hazard label. |
| Shipping | **Shipping Description:** 2-Chloro-1,4-Naphthoquinone should be shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. The package must be clearly labeled, handled with gloves and eye protection, and accompanied by the relevant safety data sheet (SDS). Comply with local and international transport regulations for hazardous chemicals. |
| Storage | 2-Chloro-1,4-Naphthoquinone should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and strong bases. Protect the chemical from moisture, direct sunlight, and sources of ignition. Ensure the storage location is secure, clearly labeled, and limits access to trained personnel only. |
Applications of 2-Chloro-1,4-Naphthoquinone in Industrial Manufacturing2-Chloro-1,4-naphthoquinone serves as a specialized chemical intermediate with established roles in high-value industrial manufacturing sectors. We apply strict controls and formulation expertise to support customers across distinct downstream fields, ensuring process reliability, adherence to industry standards, and stable supply for critical end-use products. 1. Pharmaceutical Intermediates for API SynthesisPharmaceutical companies integrate 2-Chloro-1,4-naphthoquinone as a core intermediate in the synthesis of anti-infective agents, particularly for active pharmaceutical ingredient (API) building blocks such as chlorinated naphthoquinone derivatives. Production departments use this compound during the stepwise assembly of specialty APIs where nuclear halogenation profiles are essential for biological activity, making it vital for final molecule purity and performance. Industry compliance standards
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2. Dye and Pigment ManufacturingIndustrial dye and pigment producers utilize 2-Chloro-1,4-naphthoquinone for preparing vat dyes, anthraquinone-based pigments, and specialty organic colorants. Its role is critical in forming chromophore structures, offering defined shade characteristics and wash-fastness for textile and plastic coloration. The compound’s reactivity enables targeted color tuning within multi-stage synthesis of high-performance pigments. Industry compliance standards
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3. Agrochemical Synthesis2-Chloro-1,4-naphthoquinone functions as a key precursor in the agrochemical sector, especially in synthesizing active ingredients for fungicides and bactericides applied in crop protection. Manufacturers leverage its selective reactivity for constructing halogenated naphthoquinone backbones, ensuring the resulting compounds offer persistent biological activity against plant pathogens. Industry compliance standards
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4. Specialty Polymer ModifiersPolymer manufacturers use 2-Chloro-1,4-naphthoquinone as a reactive additive to modify thermal and oxidative stability in advanced engineering thermosets and elastomers. The functionalization modifies the oxidation resistance during polymer crosslinking, and enables fine-tuning of mechanical properties desired in high-durability applications such as automotive or electrical insulation components. Industry compliance standards
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Each day at our production site, we handle countless kilograms of 2-Chloro-1,4-Naphthoquinone. The distinctive yellow crystalline powder may look unassuming, but the value it creates across industries keeps our team energized through long shifts and complex quality checks. This isn’t just another intermediate for us; it’s a model of chemical precision and reliability, often going by the shorthand 2CNQ among specialists. We know a molecule’s story doesn’t start or end in a catalog entry—ours begins in the reactors, extends to research benches across the globe, and finds new life in industries demanding both purity and consistency.
The main draw for chemists and manufacturers revolves around its reactivity. Every batch we synthesize demonstrates strong electrophilicity, thanks to the perfectly placed chlorine atom at the 2-position and the naphthoquinone backbone. This isn’t academic minutiae—reactivity determines yields in dye synthesis, acts as a lynchpin for pharmaceutical development, and guides novel material scientists searching for the next conductive or coloring agent. The smallest impurities or changes in crystalline structure can stifle those applications; we see this in both the process data we generate and the feedback labs give after trial runs. We employ multi-stage purification—distillation, crystallization, even chromatography for spot checks—because customers notice the difference in downstream processing ease and reliability.
In conversation with client laboratories and production sites, the recurring feedback is always about predictability. Workers in pigment plants tell us their outcomes track batch-to-batch without mysterious color shifts or yield swings. Pharmaceutical researchers testing new anti-infective agents report that side-product loads remain low, which shortens development cycles. Our batch records run deep, tracking process variables all the way from the chlorinating reactor to the warehouse shelves. This guarantees low residual solvents, a defined melting point, minimal metallic content, and unambiguous NMR/HPLC signatures for each shipment.
Most users want an active content above 98.5%, often pushing us to develop methods that squeeze down the last percent of byproduct from older protocols. Our in-house labs screen incoming raw materials, reacting agents, and final product to exceed both domestic and export thresholds for purity and residual limits. Color checks, handled visually and under ultraviolet, root out isomeric impurities common with naphthoquinone derivatives. Every drum or bottle that leaves our gates comes with a spectrum of test data, but for us, those sheets stand more as verification than as sales points—the real work happened in the reactors weeks before shipment.
The most common application our teams see involves its use as an intermediate for vat dyes. These colorants require sharp, defined hues and high lightfastness; our 2-Chloro-1,4-Naphthoquinone gives dyestuff makers a reliable starting block for reds, browns, and complex blended shades. On textile factory visits, operators talk about fewer filter blockages during reduction dyeing—less sludge, more usable pigment, and simplified wastewater management. This is a direct result of controlled crystal habit and low insolubles in our material, not just an accident of luck or process drift.
Agrochemicals form another backbone, where certain naphthoquinone structures act as fungicidal scaffolds. Researchers at international companies have sent us feedback that with our high-purity product, the side reactions during synthesis are reduced, making purification of the end-active far more straightforward. This translates into lower costs, less raw material waste, and more robust trial results—a trifecta that every agrochemical developer wants.
Cosmetic pigment makers and electronics researchers occasionally request higher spec material, sometimes asking for advanced packaging or ultra-low metallics. Our team handles these bespoke orders with extended purification steps, leveraging slow cooling and solvent choice to get just the right particle habit, all while backing it up with heavy metal assays and stability studies. We invest in pilot lines and backup reactors not because it looks good in an annual report, but because these requests push us forward in terms of process ingenuity and hands-on skill.
Working with many naphthoquinone derivatives means we see firsthand how 2-Chloro-1,4-Naphthoquinone carves out its space. The chlorine atom at the 2-position increases reactivity substantially compared to plain naphthoquinone, unlocking routes for nucleophilic substitutions and bridging reactions hard to achieve otherwise. Analogues like 1,4-Naphthoquinone or 2-Methyl-1,4-Naphthoquinone lack this versatility, often falling short in dye and pharmaceutical contexts. For our production floor staff, this means keeping chlorine tonnage and waste streams in check, constantly optimizing reaction conditions, and routinely recalibrating instrumentation to catch any subtle shift in output. On the bench, scientists see sharper yields; on the line, fewer surprises.
The practical upshot? Dyestuff makers choose 2CNQ for its cleaner substitution patterns, which gives more reproducible tinctorial strength. Agrochemical and pharmaceutical developers select it for the same reason—predictability, structural clarity, and the ability to push synthesis one or two steps further with less fuss over side reaction cleanups.
Open a drum of our product and you will see tightly sealed, moisture-resistant inner linings. Our packing team prioritizes protection from air and light, since even brief exposure can affect color strength on long shipments. On our own site, all isolation and packing takes place in ventilated enclosures. Operators wear full PPE, not out of procedural obligation alone, but because the material is a potent skin and respiratory irritant, something we learned quickly in our early years of making the compound. Waste handling and containment practices stay front-of-mind, with all washwaters channeled through multi-stage treatment units. Factory audits by government teams focus on these exact arrangements, with compliance driven as much by worker health as by regulation.
We keep a close line to environmental and product stewardship teams. By following regulatory evolutions—not just on the books but as interpreted in audits—our compliance department avoids last-minute headaches for both our buyers and our own site team. We’ve refined containment protocols to limit fugitive emissions, reporting process upsets proactively to local authorities, which builds trust and keeps production running smoothly.
Nothing kills momentum faster than inconsistent raw materials or a supply chain bottleneck. Our upstream chlorination unit runs tracked batches of naphthoquinone, with raw material QC baked in at delivery, pre-reaction, and pre-drum charging. Early failures in supply chain rigor led to off-spec shipments years ago, resulting in headaches for everyone. Adjusting by moving more testing in-house, booking raw material stockpile contracts, and establishing direct relationships with reliable freight partners restored that confidence. On the rare occasion that a quality drift slips through, our technical service and site visits resolve claims directly—often to the production line itself.
Over time, buyer expectations shifted from price and ton-per-year metrics toward real consistency and transparency. The most engaged customers now demand live tracking from batch synthesis through to ETA at their gates. Our own IT and process automation teams built a traceability dashboard based not on slogans, but on field experience; it gives every node in the chain immediate QC and logistics insight, saving rework and hedge-stock expenses both for us and for the user’s logistics manager.
Most improvement to our 2-Chloro-1,4-Naphthoquinone isn’t the result of market trend-watching, but direct conversations with technicians, plant managers, and R&D staff on the receiving end. Feedback loops—often through site visits, live batch tests, or even troubleshooting late-night calls—give us detail that lab instrumentation can’t always capture. For example, one dye house pointed out that subtle moisture pickup in transit led to downstream hydrolysis. By switching inner linings and adjusting drying procedures, we kept our next shipment dry enough to pass their own demanding specs.
We also involve customers in test-plotting new process tweaks. One major pigment buyer agreed to pilot a made-to-order lower-ash version, running it in parallel to their primary stock for a full production cycle. Their feedback allowed us to fine-tune our final filtration steps and build a secondary grade that now fills two distinct needs—bulk and high-purity—without disrupting our main line runs.
Some of the best advances come from the tough questions. An electronics components firm needed 2-Chloro-1,4-Naphthoquinone with near-undetectable heavy metals. This pushed us to re-map our entire utilities handling and install trace impurity reclamation. The result reduced both quality drift and environmental discharge, valuable for our own cost structure as much as for the buyer’s fab yield.
Challenges don’t come from the textbook; they show up onsite and unannounced. During heavy monsoon seasons, we learned that humidity swings in the warehouse can destabilize 2CNQ over extended storage. After a series of subpar field reports, we rebuilt both climate control and handling protocols and rotated stocks more frequently—lessons that reduced wastage for us and variability for the end user.
Legal changes around chlorinated aromatics influence very real cost and logistics factors. Restrictions in one country can force changes in global shipping patterns, from preferred carriers to container labeling. Our compliance team and shipping partners meet monthly to survey updates and anticipate shifts in import approval schemes, cutting down on surprise demurrage and customs holds. While these efforts add cost at times, avoiding disruption pays for itself in customer loyalty and stable supply for critical manufacturing windows.
Our reactor staff and lab analysts become quietly but fiercely committed to consistency. Many come from local technical schools, some with generations of family connection to the trade. They know every subtle sign of batch readiness, every tweak needed as weather shifts or raw materials vary. We run regular upskilling workshops covering not only chemical know-how but practical troubleshooting—how to spot an early crystallization issue, how to correct a weighing variance on the fly, and how to keep lines running if a pump or dryer falters.
Knowledge sharing goes in all directions. Veteran process technicians train new hires on both safe handling and quick error recovery; junior chemists in our labs develop digital SOPs that streamline documentation and reduce manual error. An open-door policy with R&D means improvements found on one shift propagate across all three. Rather than top-down orders, this collection of skill and pride keeps daily production agile and customer-facing.
Demand for 2-Chloro-1,4-Naphthoquinone doesn’t stand still. Customers hunger for both larger lot sizes and niche, ultra-refined grades. Our research group spends late nights testing greener chlorination options and re-use schemes for mother liquors. These reduce byproduct handling and cut overall waste, with economic and regulatory benefits. Both energy and solvent reductions now move at a brisker pace, spurred on by more stringent standards from multinational buyers and ourselves.
We invest in process automation and AI-guided monitoring informed by thousands of real-world batches rather than simply theoretical models. This gives early warning on leaks or off-spec readings, allowing time for in-line corrections before any finished product ever hits a drum. Automation frees up experienced staff to dig into more challenging process development, not just rote production.
From the point naphthoquinone enters our stockroom to the time a client’s sample vial passes their own QC, the work behind each shipment of 2-Chloro-1,4-Naphthoquinone is both personal and technical. Years of production data, hands-on pilot batches, direct feedback, and on-the-ground learning shape every batch, each spec tweak, and every drum and bottle we fill. Our product doesn’t exist apart from the daily discipline and pride of the people who make it. This attitude forms the real difference that experienced customers recognize and value.
Anyone searching for a reliable, highly pure supply of 2-Chloro-1,4-Naphthoquinone relies not on luck or abstract claims, but on technical rigor and real relationships. For us, ongoing improvement means more than process patents or awards. It means every user, whether a research chemist, a dyehouse technician, or a regulatory auditor, gains confidence in the product’s reliability and safety because the care we put into manufacturing is visible in every shipment.