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2-(Carboxymethylthio)Benzoic Acid

    • Product Name 2-(Carboxymethylthio)Benzoic Acid
    • Alias ALTB-4
    • Einecs 241-646-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    855123

    Iupac Name 2-(Carboxymethylthio)benzoic acid
    Molecular Formula C9H8O4S
    Molecular Weight 212.22 g/mol
    Cas Number 4317-29-3
    Appearance White to off-white solid
    Melting Point 133-136 °C
    Solubility In Water Slightly soluble
    Smiles OC(=O)Cc1ccccc1SC(=O)O
    Pubchem Cid 24521408
    Inchi InChI=1S/C9H8O4S/c10-8(11)6-14-7-4-2-1-3-5(7)9(12)13/h1-4H,6H2,(H,10,11)(H,12,13)
    Storage Conditions Store in a cool, dry place

    As an accredited 2-(Carboxymethylthio)Benzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed HDPE bottle containing 25 grams of 2-(Carboxymethylthio)benzoic acid, labeled with product name, purity, and safety information.
    Shipping 2-(Carboxymethylthio)benzoic acid should be shipped in tightly sealed containers, protected from moisture and light. Use appropriate labeling and cushioning to prevent breakage. Comply with local and international regulations for chemical transport, presenting safety data and hazard identification clearly. Ship at ambient temperature unless otherwise specified by the manufacturer or safety guidelines.
    Storage 2-(Carboxymethylthio)benzoic acid should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from sources of ignition and direct sunlight. It should be kept away from incompatible substances such as strong oxidizing agents and bases. Always store at room temperature and clearly label the container to ensure proper identification and handling.
    Application of 2-(Carboxymethylthio)Benzoic Acid

    Applications of 2-(Carboxymethylthio)Benzoic Acid in Industrial Manufacturing

    2-(Carboxymethylthio)Benzoic Acid serves critical roles in specialized chemical manufacturing sectors, where its molecular properties directly contribute to downstream product quality, process integrity, and regulatory compliance. As the direct producer, we ensure precise consistency and documentation to support high-value manufacturing in select segments. Explore major industrial uses, each reflecting real-world production environments and regulatory demands.

    1. Advanced Corrosion Inhibitor Additives for Industrial Water Treatment

    Industrial formulators utilize this compound as a targeted chelating and corrosion inhibition agent for recirculating cooling water and industrial boiler protection. Its introduction helps prevent oxidative damage and extends asset life, especially in harsh water chemistries with high chloride or sulphate concentrations. Dosage is determined after detailed system analysis to match water characteristics, regulatory thresholds, and compatibility with other treatment chemicals.

    Industry compliance standards

    • ASTM D1384 (Corrosion Test for Engine Coolants in Glassware)
    • CTI ATC-140 (Cooling Technology Institute Water Treatment Chemicals Guidelines)
    • EU Biocidal Products Regulation (BPR) for water treatment chemicals
    • ISO 14001 Environmental Management principles for effluent and additives

    Typical usage ratio

    • 10–200 ppm, depending on system size, water composition, and combined inhibitor formulations; lower range used for closed-circuit applications, higher end for challenging open systems with aggressive scaling risk

    Downstream process integration

    • Direct injection to water streams via chemical dosing pumps after coarse filtration, often as part of a multi-pronged treatment package including dispersants and anti-scaling agents
    • Quality assurance by titration and continuous flow monitoring before and after heat exchangers

    Final product types

    • Industrial cooling tower fluid blends
    • Chemical packages for boiler feedwater maintenance
    • Ready-to-use closed loop system inhibitors for HVAC or power generation

    2. Intermediates for Pharmaceutical Synthesis (API Precursor)

    Our material is supplied to pharmaceutical synthesis plants using it as a key intermediate for aromatic thioether group introductions when constructing advanced APIs involving benzoic acid derivatives. Applications focus on manufacturing cardiovascular, anti-inflammatory, and metabolic disorder medications, where side chain fidelity and impurity control in the intermediate are critical to final API quality and regulatory approval.

    Industry compliance standards

    • ICH Q7 GMP Guide for Active Pharmaceutical Ingredients
    • Pharmacopoeia references: USP, EP, JP—relevant monographs for intermediates
    • 21 CFR Part 211 (FDA - Finished Pharmaceuticals)
    • ISO 9001:2015 for chemical manufacturing and QC documentation

    Typical usage ratio

    • Used stoichiometrically as a building block—ranges from 1.0–1.5 molar equivalents relative to target API structure; excess may be applied to drive substitution/desulfurization steps, followed by downstream removal

    Downstream process integration

    • Batch-wise introduction at aromatic acylation or thioetherification steps in multi-stage API synthesis; staged addition with temperature and pH control to ensure group selectivity and minimize side reactions
    • Purification via crystallization, solvent extraction, and preparative HPLC

    Final product types

    • Advanced pharmaceutical intermediates
    • Custom API compounds with thioether-benzoic acid motifs
    • Bulk and small-scale pilot batches for both innovator and generic drug manufacturing

    3. Specialized Monomer Modifier in Industrial Polymer Additives

    Polymer compounders integrate 2-(Carboxymethylthio)Benzoic Acid as a functionalized monomer modifier to achieve controlled cross-linking, side group incorporation, and enhanced dispersion in engineering plastics and elastomers. Its structure allows for tailored sulfur-bridged frameworks in specialty resins, where standard functional monomers do not provide the required balance of reactivity and thermal stability.

    Industry compliance standards

    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (EU)
    • RoHS 3 (2015/863/EU) for plastics used in electronic components
    • UL 94 Flammability Standards for final compounds
    • ISO 9001:2015 for process quality and traceability in plastics manufacturing

    Typical usage ratio

    • 0.2–2% by weight of total monomer blend for copolymer and cross-linked resin production; exact percentage adjusted for target molecular weight, chain architecture, and application properties

    Downstream process integration

    • Continuous or batch-mode introduction during initial polymerization (solution or emulsion polymerization lines), ensuring full dissolution or dispersion prior to initiation
    • Incorporation with catalysts as part of an additive masterbatch for compound blending

    Final product types

    • Antistatic and anti-scratch engineering polymers
    • High-performance thermoset and thermoplastic elastomers
    • Modified epoxy and polyester resins for coatings, electrical, and automotive uses

    4. Ligand Agent in Hydrometallurgical Extraction

    In hydrometallurgy, operators use this acid as a specialized ligand for selective binding and extraction of certain metal ions, particularly copper and rare earths, from ores or industrial leach solutions. The carboxymethylthio group provides a strong and selective chelation platform, which allows for more efficient and environmentally responsible metal recovery under defined conditions, especially where interference from competing ions is problematic.

    Industry compliance standards

    • ISO 14001 for environmental management in mining and extraction operations
    • ISO 9001:2015 for chemical reagent production and supply chain traceability
    • Local environmental agency regulations on effluent contaminant thresholds
    • Waste management and safe handling standards (e.g., OSHA 29 CFR 1910 in the US)

    Typical usage ratio

    • 0.05–0.5% w/v in leach solutions, with dosing optimized according to ore assay, pH, and target metal/mineral species; lower end for high-grade solutions, upper end where selectivity is critical

    Downstream process integration

    • Pumped addition directly to stirred leaching tanks, followed by staged mixing and solvent extraction or precipitation; monitored by ICP or AAS analysis for chelate-metal complex formation

    Final product types

    • Electrolytically refined copper and rare earth oxides
    • Purified metal solutions for further metallurgical processing
    • Industrial chemical extractants supplied for closed-loop system reuse

    5. Analytical Reagent in Laboratory and Environmental Testing Kits

    Chemical analysis companies employ this material in the design of colorimetric reagents and metal-detection kits, capitalizing on its selective thio-chelating activity for quantifying heavy metals and trace contaminants in water, soil, and waste samples. The compound delivers high sensitivity and reproducibility in endpoint detection protocols for regulatory and quality assurance labs.

    Industry compliance standards

    • OECD Guidelines for Testing of Chemicals (Test No. 202 and other analytical methods)
    • EPA 300.0/200.7 Analytical Method standards
    • ISO/IEC 17025 Laboratory Competence accreditation
    • National metrology institutes protocols for calibrating reference reagents

    Typical usage ratio

    • 0.01–1.0% in analytical reagent formulations, with final kit dosage determined by required detection sensitivity and sample matrix composition; adjusted to minimize false positives/negatives

    Downstream process integration

    • Blending into prepared reagent solutions packaged in single-use vials or test strips during final kit assembly under controlled humidity and temperature
    • Batched under GMP-like QC management to prevent reagent cross-contamination

    Final product types

    • On-site environmental testing kits for water and wastewater
    • Heavy metal quantification strips and solutions
    • Laboratory reference reagents for trace analysis
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing 2-(Carboxymethylthio)Benzoic Acid: Purpose-Built Chemistry from the Source

    Where Precision Matters, Experience Guides

    In real manufacturing, the choices we make ripple through every batch. For anyone working with specialty chemicals, details aren’t just checkboxes — they build future product quality. People ask us about 2-(Carboxymethylthio)Benzoic Acid and what sets it apart. As a manufacturer, we have spent years refining the way this compound comes to life in our reactors, streamlining each stage without sacrificing control.

    Structure and Substance, Rooted in Practical Chemistry

    2-(Carboxymethylthio)Benzoic Acid comes from practical ideas, not shortcuts. Its structure brings together a benzoic acid ring and a thioether bridge, with the additional carboxymethyl group giving it a unique set of properties. We don’t treat this as a generic benzoic acid derivative, because the difference matters. That extra sulfur bridge isn’t just an academic talking point — it changes the solubility, the way it bonds with metals or organics, and the kind of by-products it leaves behind under heat, pressure, and pH swings.

    A lot of clients have seen standard benzoic acids disappoint when blended into more complex systems, especially if transition metals, alkali bases, or redox-sensitive substrates are part of the recipe. The carboxymethylthio group here isn’t an afterthought. Its chemical personality changes reactivity, allowing for ligation to specific metal centers where plain carboxylic or benzoic acids drop out. This can translate into more reliable performance, longer shelf life, or safer outcomes — not just on paper, but out on your plant floor.

    Specifications Forged, Not Assumed

    If there’s one lesson we’ve learned, it’s that putting numbers on a data sheet only matters if those numbers mean something in the real world. Our average purity levels typically exceed 99% by HPLC, but the story doesn’t end with percent figures. Chloride content, moisture, trace metals, and particle morphology get just as much scrutiny. Our operators work with calibrated inline probes and real-time analytic feedback — not old assumptions or “safe enough” estimates.

    Batch-to-batch reproducibility remains one of the toughest asks in specialty chemical manufacturing. Slight color differences or moisture absorption can shift downstream outcomes. To fight that drift, we don’t hand off production to “house blenders” or outsource to generic mills. Instead, we use small-lot reactors, fully controlled atmospheres, and continuous in-process monitoring, from raw material arrival through to finished packaging.

    Comparison to “Similar” Products

    Chemically, people sometimes lump 2-(Carboxymethylthio)Benzoic Acid into groups with either benzoic acid itself or with unspecific thio-acids. As anyone in the lab will tell you, this shortcut leads to headaches. Benzoic acid alone is neat, crystalline, predictable — until you need sulfur’s binding capacity or soft nucleophilicity. Plain mercaptobenzoic acids, by contrast, can bring fouling and instability, and lack the controlled carboxymethyl group that helps regulate reactivity.

    2-(Carboxymethylthio)Benzoic Acid brings both worlds together. Its extra -SCH2COOH side chain increases coordination to metals while softening reduction or oxidation issues. Think of it as adding an adjustable handle to the molecule: It grabs on where you want it to, releases when you want it to, and doesn’t leave your system unpredictable byproducts. Nobody who’s used straight benzoic or isomeric thio-benzoic acids side by side with ours fails to notice the difference.

    Often, users come to us with a challenge: a previous batch from another supplier gave them poor yields, got clumpy, or left a stubborn precipitate. The manufacturer’s workflow matters — how the compound was made, not just what went into it. For us, that means full traceability, detailed lot analytics, and never crossing lines between technical- and analytical-grade batches. You get a quantifiable distinction, not just “almost the same” chemistry.

    Use Cases Driven by Real-World Demands

    Chemistry never happens in a vacuum. In practice, folks reach for 2-(Carboxymethylthio)Benzoic Acid when ordinary benzoic acid just can’t cut it. For instance, in coordination chemistry, it becomes more than a ligand — it forms part of structured templates for metal-organic frameworks, or brings reliability to non-aqueous syntheses that collapse with sulfonic acids.

    In scale-up production, pharmaceutical intermediates and specialty resins often depend on stable sulfur-containing binders that survive both acidic and basic conditions. The thioether linkage here doesn’t cleave at mild pH, holding up where benzylic thiols or basic thioureas fall apart. We’ve watched in client trials how stability during reaction workup translates to higher recovery rates and less batch rejection.

    Researchers targeting trace-metal chelation or looking to modulate the redox stability of organometallic complexes also lean on this molecule. It strikes a balance: enough sulfur to work as a soft donor, not so much that you get unwanted side reactions or foul odors. Electroplating baths, catalyst supports, and even analytical reagent chemistries use this advantage, outpacing the old standbys for both efficiency and predictability.

    Why Direct-from-Manufacturer Quality Changes Outcomes

    The difference between “on-spec” and “fit-for-purpose” can be traced back to the source. As manufacturers, we make choices every day about raw material suppliers, reactor protocols, and packaging environments. You won’t find generic stock or repackaged intermediates on our shelves. Our chemists and engineers design every step for consistency, giving you a product that delivers the same performance in January, July, or October.

    One challenge with sulfur-containing organics lies in their tendency to develop oxidative spots, especially if exposed to stray oxygen or moisture. Relying on transit from faraway suppliers increases risk: one humid port stop can turn a high-purity grade into a maintenance headache. By packaging under nitrogen atmospheres and using specialized moisture-barrier bags, we prevent that kind of degradation before it ever leaves our site.

    We test each lot not only for structural purity, but for shelf stability under realistic lab and plant conditions: three months at 25°C, one month at 40°C, open and closed storage. These tests aren’t window-dressing — they match the situations you’ll face, whether you’re weighing for gram-scale reactions or multi-ton slabs. Our batch records detail the actual results and let you see, upfront, what kind of longevity to expect.

    Solving Application Bottlenecks with Experience

    People buy chemicals to solve problems, not to create new ones. Time after time, we see users bring up old headaches like slow dissolution, stubborn caking, or unmanageable dusting — issues that trace back to particle engineering, not just raw composition. We address these practical issues by tuning our milling and drying processes for controlled particle size and minimal fines, based on real feedback from our customers’ trials.

    In one pilot, a partner needed fast dissolution in polar aprotic solvents, with zero residue in glass reactors. Our engineers adjusted crystal growth parameters, changing both cooling rates and solvent ratios to shift particle habit. The resulting product shaved hours off downstream processing, cutting total batch time and reducing impurities. Feedback from those trials led to a permanent tweak in our production line, helping all future customers — not just the one who asked for it.

    Dust suppression sometimes means the difference between a safe operation and an environmental incident. We’ve worked directly with multinational manufacturers who need spill-proof, low-fine product for automated bulk feed. By adjusting drying and adding just the right anti-clumping steps, we meet those workplace standards, reducing product loss and airborne risks that can come from cheaper, less thoughtful production.

    Supporting Regulatory and Analytical Transparency

    You’re never left guessing what’s in the drum you receive. We believe in full analytical transparency. Each certificate comes with full chromatographic traces, NMR verification, and explicit impurity levels for real regulatory compliance — not just a “meets spec” rubber stamp. Where necessary, we provide tailored documentation for REACH, TSCA, or region-specific guidelines, with detailed dossiers built on our own validated test results, not manufacturer hearsay.

    Our plant undergoes annual third-party audits as well as regular client-initiated visits. Nothing we produce leaves the facility without strict identity confirmation, physical testing, and batch records set aside for reproducibility checks months or years later. Every single lot gets archived samples, while our analysts track trends in aging, impurity growth, and even packaging performance, learning from outcomes over time.

    Scaling for Custom Projects and New Applications

    Innovators often push chemistry beyond the catalog. We’ve supported R&D partners looking for micron-scale purity, non-standard particle shapes, or altered crystalline habits for unique applications. Through collaborative development, we create new methods and scale-up protocols, setting benchmarks the wider industry then adopts. If your process needs a tweak — say, altered solubility, lower residual solvent, or a mixed anion/cation blend — we can carry those requirements direct from pilot run to production, rather than forcing you to choose “closest fit” compounds from generalist providers.

    We treat every custom request not as an interruption but as a chance to deepen our process visibility. For example, we’ve shifted from standard aqueous isolation to solvent-free pathways for clients with ultra-strict water exclusion needs, opening up entirely new end uses. This hands-on adaptability means you actually get the chemistry that your project demands, instead of a one-size-fits-all product.

    Long-Term Support and Continuous Improvement

    The world doesn’t stand still, and neither do our standards. Since chemical supply can make or break downstream innovation, we invest in both staff expertise and facility upgrades. Seasoned chemists mentor every operator. We tweak production as new regulatory or user data comes in, not just in annual reviews. This steady feedback cycle shows in our test numbers, in client satisfaction, and in noticeably cleaner reaction outcomes on customer lines.

    We keep logs of customer feedback, not just formal complaints. Every suggestion — “what if it dissolved faster?”, “can particle sizes be made more uniform?” — informs the next production run. Over time, this constant improvement narrows variation, sharpens test results, and solves problems for the broadest possible swath of users. Our main goal isn’t just a high-purity product in a bottle; it’s chemistry that works as hard as you do, every time.

    Building Confidence Through Manufacturing, Not Marketing

    True security in your specialty chemicals comes from the reliability of the manufacturing process itself, not from promises written after the fact. Our experience as direct producers means everything about our 2-(Carboxymethylthio)Benzoic Acid — from source verification through final testing — is driven by people who understand the stakes. There’s no substitute for first-hand control over sourcing, reaction, purification, drying, and packaging.

    We’ve seen what happens when outside brokers or generic blenders get the call: product quality varies, complaints rise, and users lose track of the chemistry behind their formulations. For us, it’s all about core expertise, delivered batch after batch, year over year. Reproducibility and documented performance beat price wars or empty promises every time. Whether you’re scaling a new process or tightening up a legacy plant, that confidence shows at every step — and wins back weeks, headcount, and trust from the teams depending on those results.

    Staying Ahead: Environmental and Safety Considerations

    We take environmental stewardship seriously. Production of sulfur-containing organics poses real hazards — effluent streams, air emissions, and waste handling can’t be left for someone else to worry about. Our facilities run with onsite treatment, closed-loop solvent recovery, and multi-stage purification of both liquid and solid waste. Operators have clear protocols, and the plant’s emissions have met or exceeded local and international benchmarks for years.

    On the safety front, because 2-(Carboxymethylthio)Benzoic Acid is seldom a “bulk” commodity, its safe handling in packaging and shipment counts twice over. Our teams document every loadout, use correct labeling, and adjust transport plans for seasonal risk factors like humidity spikes or transit slowdowns. Clients get material that works — not product that failed in transit, or that needs remediation upon arrival.

    From Source to Application: Why the Right Chemistry Matters

    Working with true manufacturing partners offers practical benefits. You get real answers about timeline, technical details, and how the compound actually performs in finished use. If you’ve ever had to troubleshoot a paint formulation, polymer blend, plating bath, or pharma intermediate because your compound was “almost right,” you know that source quality makes the difference between downtime and consistency. Our 2-(Carboxymethylthio)Benzoic Acid reflects what experience, care, and hard work deliver. We stand behind every drum and bottle, not just because our name is on it — but because our teams are the ones who crafted it from start to finish.

    Looking Ahead: Maintaining Standards in a Changing Industry

    Regulatory landscapes shift. End-user applications grow more demanding. Our aim stays the same: reliable, high-purity 2-(Carboxymethylthio)Benzoic Acid that gets you the results your downstream processes need. Through ongoing investment in analytics, training, waste treatment, and feedback-driven tweaking, we set a standard that goes beyond minimum compliance. The best specialty chemicals don’t just meet specs; they earn trust where it matters most — in real plants and daily operations.

    In sharing our process and philosophy, we don’t just invite business. We open ourselves to scrutiny and promise to keep earning the confidence of every user. For us, product and reputation go hand in hand, each new batch a marker of the craft and precision our teams build every single day.