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2-Bromovaleric Acid

    • Product Name 2-Bromovaleric Acid
    • Alias 2-Bromopentanoic acid
    • Einecs 209-116-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    747777

    Chemical Name 2-Bromovaleric Acid
    Cas Number 625-68-1
    Molecular Formula C5H9BrO2
    Molecular Weight 181.03 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 125-127°C at 14 mmHg
    Melting Point -8°C
    Density 1.474 g/cm³ at 20°C
    Purity Typically ≥98%
    Solubility Soluble in organic solvents, limited solubility in water
    Synonyms alpha-Bromovaleric acid
    Smiles CC(CC(=O)O)CBr
    Inchi InChI=1S/C5H9BrO2/c1-2-4(6)3-5(7)8/h4H,2-3H2,1H3,(H,7,8)
    Refractive Index 1.461-1.463

    As an accredited 2-Bromovaleric Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Bromovaleric Acid is supplied in a 100g amber glass bottle with a secure, chemical-resistant cap and detailed hazard labeling.
    Shipping 2-Bromovaleric Acid is shipped in secure, airtight containers to prevent leakage or contamination. The container is clearly labeled with hazard information due to its corrosive and irritant nature. During transport, it is protected from moisture, heat, and incompatible substances, in compliance with all relevant chemical shipping regulations and guidelines.
    Storage 2-Bromovaleric acid should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of heat, ignition, and incompatible substances such as strong oxidizers or bases. Protect it from moisture and direct sunlight. Use appropriate chemical storage cabinets, preferably with secondary containment, and clearly label the container to ensure proper handling and safety.
    Application of 2-Bromovaleric Acid

    Applications of 2-Bromovaleric Acid in Industrial Manufacturing

    As the direct manufacturer of 2-Bromovaleric Acid, we support multi-disciplinary industries through precise synthesis and process control. Our application guidance focuses on validated, value-adding use cases driven by formulation standards, regulatory needs, and efficiency targets in downstream sectors.

    1. Pharmaceutical Intermediates for Antiepileptic Drugs

    Major pharmaceutical companies incorporate 2-Bromovaleric Acid as a key intermediate in the synthesis of anticonvulsant compounds, such as valproic acid derivatives. The chemical structure allows for controlled bromination and further transformation, enabling stepwise construction of medical molecules. The raw material must meet strict impurity thresholds and traceability standards, with robust documentation. Manufacturers typically blend it in designated reactor vessels under controlled temperature, followed by hydrogenation and functional group conversion to reach final APIs.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF and EP monograph requirements for process intermediates
    • FDA 21 CFR Part 211 for finished pharmaceutical manufacturing
    • REACH Registration, specific to precursor material controls

    Typical usage ratio

    • 0.8–1.3 molar equivalents per batch, adjusted for desired yield and downstream reactivity

    Downstream process integration

    • Charged into glass-lined reactors after catalyst and solvent charging, monitored by in-process GC-MS analysis

    Final product types

    • Sodium valproate API
    • Valproic acid prodrugs
    • Antiepileptic finished dosage forms (tablet, syrup)

    2. Agrochemical Synthesis for Herbicidal Actives

    Agrichemical producers incorporate this brominated acid in the construction of specialty herbicide molecules, particularly in the assembly of five-carbon backbone intermediates. The product’s purity and control of side-chain halides ensure stable reactions and low toxic byproducts, key for regulated pesticide development cycles. Blending takes place in sealed batch reactors, following upstream acylation or protection steps, as manufacturers prepare the intermediates for heterocyclic closure or direct conjugation.

    Industry compliance standards

    • ISO 9001:2015 for agrochemical production quality management
    • FAO/WHO specifications for technical materials
    • EPA Title 40 CFR Part 180 tolerances for herbicide active ingredients
    • Globally Harmonized System (GHS) for safe handling and labeling

    Typical usage ratio

    • 5–15% by weight relative to main reactant, based on synthetic route and target herbicide structure

    Downstream process integration

    • Added during acylation or bromination step, followed by quenching, neutralization, and distillation for purity control

    Final product types

    • Precursor for phenoxyalkanoic herbicides
    • Pyridine-based weed management compounds
    • Final technical grade emulsifiable concentrate (EC) products

    3. Synthesis of Flavors and Fragrance Esters

    Fragrance and flavor houses use 2-Bromovaleric Acid as a building block for high-value esters and lactones imparting fruity and creamy notes in compounded aromas. Controlled reactions with selected alcohols—often under strong acid catalysis—transform the acid into volatile esters, which require stringent purification and batch record-keeping. The feedstock quality (residual bromide, volatility) plays a major role in both safety and consistency for food and cosmetic end use.

    Industry compliance standards

    • IFRA (International Fragrance Association) code of practice
    • EU Regulation (EC) No 1334/2008 on flavorings
    • ISO 9001 for quality consistency
    • FDA 21 CFR 172.515 for food additive status

    Typical usage ratio

    • 3–10% w/w with reactant alcohol depending on ester chain length and olfactory profile required

    Downstream process integration

    • Charged at the start of esterification reactors after solvent wetting, with acid and alcohol dosing stepwise, followed by fractional distillation and GC-based aroma profiling

    Final product types

    • Butyl valerate flavoring esters
    • Gamma-decalactone precursors
    • Perfume base stock for personal care

    4. Specialty Monomer Synthesis for Advanced Polymers

    Producers in the specialty polymer and advanced materials industry utilize this compound as a precursor for α-bromo functionalized monomers. These monomers enter radical and controlled/living polymerization lines, enabling fine-tuned copolymer properties for automotive, electronics, and specialty coating sectors. The material’s defined reactivity and chain length support block copolymer architectures and surface modification chemistries. Users track batch-to-batch consistency by FTIR and NMR to meet downstream validation.

    Industry compliance standards

    • ISO 14001 Environmental Management System for chemical processing
    • RoHS Directive compliance for electronics applications
    • REACH Annex XVII for monomer restriction
    • TSCA Inventory listing for US manufacturers

    Typical usage ratio

    • Variable—usually 0.5–2.5 mol equivalents per chain-initiator or seed, based on polymer target architecture and chain length

    Downstream process integration

    • Introduced post-initiation as a functionalization agent in solution polymerization tanks, with downstream purification via precipitation and controlled chain-end analysis

    Final product types

    • Block copolymers for adhesives
    • Functionalized acrylic or urethane oligomers
    • Tailored silicone-based surface coatings

    5. Fine Chemical Manufacturing for Custom Halogenation

    Custom chemical contract manufacturers purchase this material for introducing controlled bromination into C5 or longer carbon skeletons, which later transform into specialized fine chemicals, ligand precursors, or catalyst supports. Process chemists emphasize purity, defined alpha-position halogenation, and minimal side-reactions. Loading generally follows a validated proportion to substrate, paired with in-process QA and traceable batch records, as product value often depends on downstream coupling efficiency.

    Industry compliance standards

    • ISO 9001:2015 for documented production processes
    • REACH compliance for transport of halogenated organics
    • OECD guidelines for testing and reporting of intermediates
    • OSHA 29 CFR 1910.119 for reactive chemical management

    Typical usage ratio

    • 8–20% w/w relative to main substrate, depending on halogenation depth and residual analysis by NMR

    Downstream process integration

    • Metered into halogenation reactors under inert conditions, preceding downstream coupling, oxidation, or palladium-catalyzed cross-coupling steps

    Final product types

    • Halogenated ligand building blocks for catalysis
    • Specialty organobromine compounds for electronics
    • Intermediates for custom fine chemical blends
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    Certification & Compliance
    More Introduction

    2-Bromovaleric Acid: A Practical Perspective from Our Production Floor

    What We Make, What We Use, and Why 2-Bromovaleric Acid Matters

    In chemical manufacturing, few compounds get overlooked for their value and impact more than 2-Bromovaleric Acid. As a producer with hands-on experience, we know this compound goes far beyond the simple formula C5H9BrO2. Daily, we see its role in shaping synthesis routes, enabling specialized intermediates, and supporting constant requests from both research and scale-up applications. Over the years, it’s become clear that the real-world reliability of 2-Bromovaleric Acid is shaped as much by how it’s made as what it’s used for.

    Quality from the Reactor to the Drum

    Every batch leaves our reactors with strict attention to purity. The main model we make features a clear, colorless to slightly yellow liquid with a distinct odor, reflecting careful control over each step, from bromination right through to purification and packaging. We regularly monitor for common by-products like dibromo-derivatives or residual valeric acid and tweak processes to keep them far below detection thresholds. Test results often show purity above 98%, with a focus on a narrow acid value and moisture content to ensure reproducibility for even demanding applications.

    Handling and Storage Insights—Why They Matter to Performance

    Storing 2-Bromovaleric Acid often gets overlooked until a drum sits too long and starts to show discoloration or a faint but unmistakable halogen tang in the air. Years of moving drums from the filling line to shipment tell us the acid fares best in cool, dry areas, sealed in high-density polyethylene or glass that resists both the acid and the bromine atom’s urge to creep out. We see shipment failures drop when users remember to reseal containers tightly and avoid exposure to humidity—something that keeps both quality and shelf life where they should be.

    Usage Realities in Synthesis and R&D

    Our product rarely sits idle. Chemists and process engineers rely on its reactive bromo group for alkylation, acylation, and more intricate transformations. In research settings, 2-Bromovaleric Acid builds carbon frameworks, lends itself to forming heterocycles, or introduces controlled functional handles for downstream chemistry. Its carboxylic function opens routes for ester and amide formation, which turns out to be highly useful when designing analogues or creating building blocks for pharmaceuticals, especially for chain-elongation strategies.

    On the pilot-plant side, the acid’s liquid state, moderate boiling point, and manageable viscosity let us scale reactions without fuss. A properly prepared batch reacts predictably with amines, alcohols, or bases, delivering consistent conversion rates. Feedback from long-time users tells us the difference between lab-bench and ton-scale handling isn’t dramatic if we stick with stable, high-purity lots.

    Comparing with Other Halogenated Acids

    Colleagues often ask if 2-Bromovaleric Acid competes directly with its cousin 2-Chlorovaleric Acid or even straight-up Valeric Acid. From the manufacturing and application angle, each finds its niche. The brominated version activates more readily in substitution and coupling steps, which means faster reaction rates and fewer harsh conditions during alkylations. In contrast, chlorinated analogs often require more extreme conditions or catalysts and still give lower conversions in some key synthetic routines.

    Pure Valeric Acid lacks the reactivity for a wide swath of modern transformations. While it serves well in basic alkyl chains or as a solvent component, only brominated analogs offer the two sites of orthogonal reactivity that open so many options for advanced intermediates. Customers looking for the combination of a reactive handle and a carboxylic group keep coming back for brominated acids, particularly as more pharmaceutical scaffolds incorporate halogen-substituted side chains.

    Control Over Contaminants: What Sets Quality Apart

    Every manufacturer promises high quality. In our daily work, the difference comes from how closely we watch for trace contaminants—iodides, residual alkali, color pickups from corroded tanks, or leftover processing aids that escape conventional filtration. Over the years, shifting to closed-system reactors, refining workup steps, and using in-line sensors for purity assessment help us tackle these challenges. We don’t stop at industry minimum standards; repeat customers know we tackle very low ppm levels that might trigger headaches in polymerization or specialty pharma work.

    Tech support teams often share reports from customers noticing cloudiness or side reactions caused by halide slippage outside stated control ranges. Tracking down the culprit sometimes leads back to a minor impurity in a single drum that escaped detection. This highlights why we push for full traceability and lot-by-lot analytics, not just meeting paperwork requirements but catching drift in bromide ratios, carbonyl indices, or acidity that can ruin a batch at scale.

    Building Relationships with Users—Learning from Their Workshops

    Every user faces real-world hurdles deploying 2-Bromovaleric Acid. Some research groups want slightly different acid values to tune their esterification rates. Others need better stability in stored bulk lots, especially for seasonal production schedules. Over time, these needs make their way back to our shop floor, driving improvement cycles and the occasional process tweak.

    We’ve worked closely with teams developing creative uses in flavors, fragrance precursors, or new materials for electronics, and every feedback loop saves both sides time and resources. By tracking which impurities or physical properties matter most to a given downstream process—whether it’s a color change, a shelf-life issue, or an odor profile affecting workplace acceptability—we’ve adjusted everything from washing steps to the design of storage tanks.

    Some collaborative efforts have even led to custom lots: for example, reduced residual halogen for polymer work or tweaks that suppress off-notes for flavor applications. In pharmaceutical synthesis settings, we sometimes produce runs with even tighter limits on water content and trace metal contamination. Years of adapting to end-user feedback taught us the limits of generic “meets spec” supply and the real cost savings in supporting tailored approaches.

    Safety and Regulatory Considerations—What On-the-Ground Compliance Looks Like

    No chemical manufacturer can ignore evolving safety and environmental standards around brominated chemistry. Local and international guidelines keep tightening around halogenated organics. From years of audits and environmental assessments, we know that simple mistakes in labeling, packaging, or residue management can lead to unexpected waste costs or compliance dilemmas.

    On our floor, handlers wear robust PPE, and spills get immediate attention. Ventilation systems draw off the distinctive, sometimes persistent smell of brominated acids early in the process. Teams carry out waste handling under inspection, making sure trace acid and vapor releases never exceed local permitted levels. Waste streams pass through neutralization and filtration treatments before anything goes off-site.

    Working closely with regulators has helped pair our in-house efforts with bigger industry moves toward sustainability. Investing in bromine recovery and destruction units keeps our emissions and waste as close to zero as achievable. Collaborating with clients on container reuse and effective drum returns closes the loop both environmentally and financially.

    Why this Matters in the Research to Production Pipeline

    Handling and synthesizing with 2-Bromovaleric Acid asks for repeatability and safe operation from the start. In our experience, pilot batches often reveal development issues that paper chemistry doesn’t predict—such as microcrystalline precipitate formation, viscosity shifts under different temperatures, or unexpected interactions with catalyst systems. Pre-empting these bottlenecks requires a steady hand, real-world handling know-how, and continuous communication with process chemists and engineers.

    We support smaller research projects just as carefully as full-scale industrial syntheses. That means single-drum shipments with the same analytics as full containers, helping academic or startup teams avoid scaling headaches or surprise impurities during crucial tests. This approach comes not from just chasing sales, but from the recognition that trust and transparency drive long-term demand and smoother product rollouts.

    Behind the Numbers: What End Users Often Ask

    Specs sheets just scratch the surface of what chemists and production engineers want to know. Most questions that come our way focus on batch-to-batch consistency, ease of transfer from lab bench to plant, and troubleshooting for downstream processes. Researchers value a direct dialogue about supply security, shelf life under various climates, and the practicalities of handling an acid with a bromo group in bulk. Commercial operators tend to push for documentation on past customer uses, audits, and the real impact on final product quality.

    Our experience suggests the single most common user concern remains drift in purity or the presence of odor- or color-forming impurities. We back up every shipment with rigorous, traceable analytics and have a standing policy allowing for test-run samples—no surprises, no last-minute recalculations required. Industrial end users often stop buying from generic traders and switch to us after getting burned by undetected trace contaminants or slow-shipping re-packed products that degrade in transit.

    Advances in Production—What Has Changed and What Has Stayed the Same

    Over the past decade, we have streamlined synthesis through everything from greener brominating agents to fully automated flow reactors. This shift means more uniform product quality, fewer by-products, and a safer working environment. Yet, the core steps—preparing precursor acids, controlled bromination, and vigilant purification—remain the backbone of every batch leaving our site.

    On the logistics front, investing in temperature-stable transport and optimizing drum design for minimal headspace and vapor escape have led to dramatic improvements in product shelf life and user acceptance. With every improvement, we have more data showing longer periods of active use without degradation and a sharp drop in return or replacement requests from users worldwide.

    Industry Challenges and Opportunities: An Insider’s Take

    It’s easy to overlook the constant pressure on raw material pricing, sourcing of bromine, and supply chain hiccups that strike every chemical manufacturer. What keeps successful producers ahead is agility—switching suppliers, locking in long-term contracts, and building redundancy into shipping logistics for global users. Our plant managers live through these cycles and keep customers informed about real timeframes and alternate sourcing, especially as regulatory or shipping crises hit.

    While larger end-users sometimes carry reserves, smaller groups depend on honest feedback. We offer real-time production updates, transparent lead times, and clear explanations about what drives any cost changes. Most long-standing customers point out that clear communication about raw material or logistics issues makes our service as valuable as the product in the drum.

    Future Prospects—Where We See Demand Growing

    As more industries look to halogen-modified intermediates for advanced materials, specialty pharmaceuticals, and even emerging sectors like agricultural chemistry, the need for high-quality 2-Bromovaleric Acid rises. Advances in fine chemicals, new catalyst systems, and custom-designed organic molecules all favor compounds with both reactivity and flexible integration options. Research collaborations with institutes and large industrial players keep us tuned in to new requirements, sometimes years before the demand peaks.

    On the sustainability front, brominated compounds face greater scrutiny than ever. We’re tackling these concerns at the source with recovery, containment, and waste minimization investments that assure buyers of responsibility all the way from synthesis to disposal. Shifting to greener process inputs and working closely with downstream users to reduce environmental impact forms part of our everyday mission and long-term strategy.

    Why Source Direct From the Manufacturer

    After years in the industry, one trend stands out: users demanding direct supply links to manufacturers. When communication runs only through repackagers or resellers, miscommunications pop up: missed specification changes, degradation from re-bottling, and wild swings in analytical quality. Supplying direct means we can troubleshoot, support, and adapt with far greater speed and accuracy. Product leaves our site with confidence, not guesswork, and feedback gets routed straight to people who can solve problems, not just pass on paperwork.

    The Bottom Line—Meeting Real Needs With Real-World Product Knowledge

    2-Bromovaleric Acid isn’t just a line item in our catalog; it’s a daily test of manufacturing discipline, application knowledge, and industry responsibility. By focusing on detailed analytics, customer-driven tweaks, and open lines of communication—combined with a commitment to safety and environmental stewardship—we support every use case, whether it’s a boutique synthesis or a new batch destined for global distribution. The acid’s role in everything from pharma intermediates to performance chemicals continues to grow, and each improvement comes out of concrete feedback and real-world experience, not just numbers on a spec sheet. We treat every request as an opportunity to both deliver and learn, keeping the value chain robust from the reactor to the research lab and beyond.