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2-Bromoethyl Acrylate

    • Product Name 2-Bromoethyl Acrylate
    • Alias 2-Bromoethyl 2-propenoate
    • Einecs 'EINECS: 221-492-8'
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    565670

    Chemical Name 2-Bromoethyl Acrylate
    Cas Number 5888-40-2
    Molecular Formula C5H7BrO2
    Molecular Weight 179.01 g/mol
    Appearance Clear to pale yellow liquid
    Boiling Point 62-64°C at 13 mmHg
    Density 1.462 g/mL at 25°C
    Refractive Index 1.457-1.459 at 20°C
    Flash Point 97°C
    Solubility Slightly soluble in water; soluble in organic solvents
    Smiles C=CC(=O)OCCBr
    Storage Temperature 2-8°C

    As an accredited 2-Bromoethyl Acrylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Bromoethyl Acrylate is packaged in a 100-gram amber glass bottle with a tamper-evident cap and hazard labeling.
    Shipping **Shipping Description for 2-Bromoethyl Acrylate:** 2-Bromoethyl Acrylate should be shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. Label as a hazardous material according to local regulations. Handle with care, avoiding extremes of temperature. Transport using appropriate chemical packaging and documentation required for flammable and potentially toxic organic chemicals.
    Storage 2-Bromoethyl Acrylate should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep it separate from acids, bases, oxidizing agents, and moisture. Store below 25°C if possible. Use appropriate chemical storage cabinets, and label clearly. Avoid prolonged exposure to air or light to prevent decomposition or polymerization.
    Application of 2-Bromoethyl Acrylate

    Applications of 2-Bromoethyl Acrylate in Industrial Manufacturing

    As a specialized manufacturer of 2-Bromoethyl Acrylate, we supply this monomer for select, performance-oriented sectors where its unique reactivity and halogen functionalization support advanced chemical synthesis and materials engineering. Below, we outline key downstream segments where this intermediate plays a proven and integral role in production, formulation, and quality-controlled processes.

    1. Synthesis of Reactive Acrylic Polymers for Adhesive Systems

    Adhesives and sealant formulators incorporate 2-Bromoethyl Acrylate as a reactive comonomer to introduce pendant bromoalkyl groups into polymer chains, enabling controlled post-polymerization modification. This intermediate empowers production of acrylic copolymers that achieve high-performance adhesion and customizable cross-link density for challenging substrates in automotive assemblies and electronics encapsulation. The raw material enters early in the bulk or emulsion polymerization stage, precisely measured based on the desired nucleophilic reactivity of the end product.

    Industry compliance standards

    • ISO 9001:2015 for quality management
    • ASTM D1002 and D3165 for adhesive bond strength requirements
    • REACH Annex XVII, SVHC monitoring for specialty monomers in adhesives
    • RoHS Directive (EU) 2011/65/EU for electronic applications

    Typical usage ratio

    • 2–10% by weight of the monomer component, adjusted according to target polymer backbone functionality and desired cross-linking capacity

    Downstream process integration

    • Introduced during in-situ copolymerization along with acrylic esters and comonomers in the reactor vessel under nitrogen protection; post-polymerization alkylation or functionalization follows depending on the end-use requirement

    Final product types

    • Structural adhesives
    • High-performance automotive sealants
    • Surface primers for electronics
    • Encapsulation resins

    2. Chemical Intermediates for Pharmaceutical API Synthesis

    Fine chemical producers use 2-Bromoethyl Acrylate as a building block for the preparation of pharmaceutical active ingredient precursors, leveraging its bifunctional moiety in creating carbon–carbon and carbon–heteroatom bonds. Its well-defined chemical purity and high reactivity make it suitable for integration within GMP-controlled multi-step synthesis, especially for compounds requiring terminal alkylation or as an intermediate in medicinal chemistry directed libraries for small-molecule APIs.

    Industry compliance standards

    • ICH Q7A Guidelines for Good Manufacturing Practice
    • 21 CFR Part 211 (FDA cGMP for Finished Pharmaceuticals)
    • EU GMP Volumes 4 Part I & II
    • USP <823> requirements for chemical purity and traceability

    Typical usage ratio

    • Stoichiometric usage with 1.05–1.20 equivalents per reaction, calculated based on molar conversion requirements in stepwise synthesis to minimize byproduct formation

    Downstream process integration

    • Used in nucleophilic substitution, Michael addition, or cross-coupling steps during route scouting and process optimization for pharmaceutically relevant intermediates; handled in validated containment under fume control

    Final product types

    • API intermediates with alkyl or halogenated moieties
    • NCEs (New Chemical Entities) libraries
    • Key precursors for late-stage pharmaceutical synthesis
    • Contract-manufactured chemical scaffolds for drug discovery

    3. Specialty Acrylic Resins for UV-Curable Coatings

    Producers in the high-performance coatings sector apply 2-Bromoethyl Acrylate to tailor acrylic resin backbones for UV-curable systems. The monomer’s bromoethyl functionality imparts improved wetting, adhesion to difficult substrates, and enables subsequent grafting with silanes or amines, aligning with trends towards solvent-free, fast-curing formulations. Quality assurance follows ISO and industrial standards for coating raw materials safety and composition.

    Industry compliance standards

    • ISO 12944 for protective coatings
    • EN 71-3 for coatings in toys and consumer goods (where applicable)
    • ASTM D7767 for UV-cured coating performance
    • Directive 2004/42/EC (VOC content in coatings)

    Typical usage ratio

    • 1–8% by weight as a comonomer, balanced according to resin formulation and target mechanical property profile

    Downstream process integration

    • Metered into pigment paste or binder synthesis stage in combination with diacrylates/multifunctional acrylic monomers; in-situ monitored for viscosity and reactivity during high-shear mixing prior to photoinitiator addition

    Final product types

    • UV-curable clear and pigmented coatings
    • Industrial overprint varnishes
    • Optical display and touch panel coatings
    • Protective floorings and anticorrosion films

    4. Functional Monomers for Ion Exchange Resin Manufacture

    Water treatment and specialty separation industries leverage 2-Bromoethyl Acrylate as a functional monomer to introduce active halide sites, which are further derivatized via nucleophilic substitution to yield tailored ion exchange resins—especially for chelating, catalytic, or softening purposes. Manufacturers ensure compliance with rigorous water contact and chemical durability standards throughout synthesis and bead polymerization processes.

    Industry compliance standards

    • ANSI/NSF 44 for cation exchange water softener resins
    • EN 15039 (Europe) on performance of ion exchange resins in water treatment
    • ISO 9001:2015 for quality assurance in polymer manufacturing
    • REACH registration for polymer constituents

    Typical usage ratio

    • 5–20% by weight of total monomer composition, adapted according to ion exchange capacity and desired degree of post-polymer modification

    Downstream process integration

    • Added to suspension polymerization reactors as a functional comonomer; after bead formation, the pendant bromo group undergoes derivatization with amines, thiols, or ammonia to produce active ion exchange sites

    Final product types

    • Chelating resins for heavy metal removal
    • Cation/anion exchange softener beads
    • Selective resin adsorbents for industrial process streams
    • Catalytic resins used in organic synthesis flows

    5. Macroinitiator Synthesis for Controlled Radical Polymerization

    Advanced polymer synthesis labs and industrial producers exploit the bromoethyl moiety in controlled/living radical polymerization (ATRP, RAFT, SET-LRP) to introduce well-defined initiation sites on substrate polymers or small molecules. This process allows the production of block copolymers with precise architecture for high-value specialty materials. Tight quality control and process documentation are required to comply with specialty polymer purity and performance specifications.

    Industry compliance standards

    • ISO 22196 for antibacterial materials (when target substrate requires)
    • ISO 14001 for environmental management in specialty polymer production
    • REACH and TSCA premanufacture notification for specialty intermediates
    • QA agreement requirements for contract synthesis clients

    Typical usage ratio

    • 0.5–5 mol% relative to macroinitiator or matrix polymer feeding ratio, precisely calculated to control initiation density and polymer chain length

    Downstream process integration

    • Dosed during initial macroinitiator preparation with copper or ruthenium catalyst systems – control of reagent addition and temperature are rigorously maintained to ensure reliable functionalization

    Final product types

    • Block copolymers for thermoplastic elastomers
    • Specialty dispersants and surfactants
    • Star and graft polymers for advanced coatings
    • Functionalized carrier polymers for drug delivery research
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    Certification & Compliance
    More Introduction

    2-Bromoethyl Acrylate: A Closer Look from the Manufacturer’s Bench

    Our team has worked with 2-Bromoethyl Acrylate for years, so we know firsthand where this chemical truly shines and where its complexities demand careful attention. We come across raw acrylate monomers every day, but compounds like this one build in a layer of versatility that standard acrylates just can’t match. We make each batch in our own reactors, constantly checking purity and responding to feedback from polymer, pharmaceutical, and specialty chemical partners. This commentary sheds light on what it’s really like to produce, handle, and apply 2-Bromoethyl Acrylate in a world of ever-shifting technical requirements.

    What Sets Our 2-Bromoethyl Acrylate Apart

    We produce 2-Bromoethyl Acrylate under controlled conditions, aiming for a reliable model specification—most batches land at 98% minimum purity, clear to pale yellow liquid, and moisture levels below 0.2%. Packing and sealing matter as much as the synthesis itself; we've learned how environmental moisture can trigger hydrolysis far too quickly, so we use nitrogen blanketing and properly lined containers to help keep hydrolysis at bay during transit and storage.

    From a manufacturing perspective, achieving this standard is no small feat. We run regular gas chromatography and NMR tests because side reactions can sneak up during esterification and purification. Batches that don’t meet our quality benchmarks never leave the QC lab. Chromatograms often tell stories about raw material integrity and process tuning that spreadsheets can’t capture. It’s one thing to hit a spec sheet; it’s another to maintain consistency over hundreds of runs.

    Role and Value in Research and Industry

    Out in the field, 2-Bromoethyl Acrylate attracts attention from chemists working in surface modification, functional polymer synthesis, and pharmaceutical research. The bromine gives it a site for mild nucleophilic substitution, making it more than just a typical acrylate. Our materials end up in everything from smart coatings and hydrogels to advanced intermediates in drug discovery.

    One of our large-scale partners looked to incorporate specific ion-responsive groups onto polymer chains, and the reactive handle from the bromoethyl side chain accelerated their workflow. There’s no need for pre-functionalized acrylates when the bromoethyl group gets the job done with a single, concise step. We’ve also seen research teams adapt this compound to craft functional crosslinkers in medical hydrogel systems, pushing the performance and function far beyond that of methyl or butyl acrylate-based polymers.

    The innovation flows both ways. Customers call us with stories of novel block copolymer architectures or polymer brushes for sensors and diagnostics. Many of those ideas rest on the unique combination of acrylate reactivity and the selective handle of the bromine group. We learn about bottlenecks in scale-up—such as product stability, handling aggravations from volatility, or regulatory hurdles—and come back to our own operations to find process tweaks. That loop of feedback and improvement keeps the material both practical for routine use and open to new applications.

    The Distinct Edge Over Other Acrylates

    We’ve synthesized and handled most common acrylates, and the differences matter in practical production. Standard methyl, ethyl, or butyl acrylate monomers have limited handles for post-polymerization chemistry. In contrast, 2-Bromoethyl Acrylate brings in a two-carbon spacer followed by a bromide, opening up pathways for SN2 substitution, azide-alkyne cycloaddition, or even Suzuki-type couplings. Those capabilities let downstream chemists build up family trees of custom polymers or molecular scaffolds without multi-step, low-yield functionalization schemes.

    There’s tradeoff. Compared to its simpler cousins, this compound requires stricter handling—the bromine adds reactivity, but also calls for more care to avoid side reactions or loss through hydrolysis. Our plants aren’t set up to use generic off-the-shelf process gear; we use corrosion-resistant equipment and design each batch reaction and workup with a mind toward keeping the active bromine available without generating unwanted byproducts or excessive waste streams. We train our team to spot subtle shifts in color, smell, and viscosity, since the smallest sign of off-spec hints at early decomposition or unwanted polymerization onset. No checklist or automated sensor replaces an operator’s senses here.

    Experience with Handling and Process Safety

    On the shop floor, no one mistakes this monomer for the friendlier acrylates. Its volatility and sensitivity make personal protective gear mandatory, and we insist on local ventilation at the point of fill and packaging. Our team always works with dedicated pumps and hoses—cross-contamination with more common esters or hydrocarbons threatens downstream polymer quality and reduces overall lot performance.

    We learned hard lessons about stabilizer choice early on. Some cost-cutting approaches relied on simple phenolic inhibitors, but we saw higher storage losses and lower color stability over time. These days, every outgoing drum uses a rigorously tested mix of stabilizers, titrated against current shipment distances and storage conditions reported by the customer. If the order ships to a climate-controlled warehouse, we might reduce stabilizer load; for field shipments through summer heat, we advise extra measures, including early QA check-ins from the recipient.

    Micro-leaks from packaging seals once led to measurable hydrolysis before customer delivery. Since then, we’ve redesigned our seal-and-pack stations, implemented leak detection checks, and qualified each lot’s cap torque and liner material with staged stress testing. Building chemical trust goes beyond molecule structure—it takes hard-won practice on the line.

    Common Uses and Industry Successes

    Pharmaceutical teams benefit from 2-Bromoethyl Acrylate’s balance of solubility and reactivity. Its bromoethyl pendant makes it an excellent intermediate for multi-step syntheses, sometimes building up PEGylated frameworks or attaching bioactive side chains for prodrug strategies. Analytical feedback from our customers tells us that yields jump when swapping this acrylate for the less reactive, non-brominated relatives. Fewer steps to reach a finished analog saves precious time in medicinal chemistry campaigns where speed means getting a clinical candidate to review ahead of schedule.

    In coatings and materials chemistry, the bromoethyl acrylate moiety has found a home—especially where advanced adhesives or high-performance films need sites for further crosslinking or surface attachment. The flexibility of the two-carbon spacer, along with the manageable reaction rates of the acrylate group, mean formulators fine-tuning viscosity, flexibility, or cure profiles appreciate the compound’s predictable reaction profile. Often, products that used to settle for generic acrylates are moving up the complexity ladder by leveraging bromoethyl acrylate’s dual functionality.

    We’ve seen high-growth work in sensor technology and nanomaterials, too. Research teams create tailored surfaces, attach ligand libraries, or build up smart interfaces by exploiting the selective reactivity on the bromoethyl side. Some of the most interesting progress has landed in environmental monitoring, where tiny changes to polymer structure enabled by this compound have meant higher sensitivity and stability in the final sensor platforms.

    What We Wish People Knew Before Working With It

    Anyone coming from a background of using standard acrylates skips a few assumptions with 2-Bromoethyl Acrylate. We talk frankly to new customers about storage: even small leaks or standing moisture lead to significant product degradation. Where many acrylates can share bulk storage facilities with little change across weeks, our experience says bromoethyl acrylate gets best results only with dedicated, dry, and temperature-controlled settings. This is especially true if you wish to maintain reactivity for advanced functionalizations.

    Our technical support spends a lot of time walking downstream teams through dosing setups. Agitation rates, order of addition, and base selection all affect product integrity. Trialing changes at the bench before scaling up avoids costly reactor fouling or sub-par yields. We keep logs of common pitfalls, from microbubbles in cast films to unusual gel times in polymerizations, and share those observations on request. The manufacturing challenges aren’t a deterrent; they’re the real business of fine chemical work.

    Comparing Bromoethyl Acrylate with Similar Compounds

    Many customers consider whether 2-Chloroethyl Acrylate or 2-Iodoethyl Acrylate could fit their process as well, but our perspective favors the bromide for a reason. Chain transfer rates, volatility, and ease of substitution balance best in the bromoethyl variant. Iodoethyl acrylate brings increased cost and lower shelf life, while chloroethyl provides slower reactions and often less secure attachment post-polymerization. We stock alternative halide ethyl acrylates for R&D, but once scale-up begins, the bromo derivative wins out most frequently for both performance and value.

    Customers sometimes ask about direct comparison to 2-Hydroxyethyl Acrylate, especially for hydrophilic polymer work. The hydroxy group enables hydrogen bonding but lacks the reactive handle for further elaboration. For high value-add applications—such as attaching peptides, fluorophores, or bulky groups reliably—the bromoethyl structure gives much more freedom. It’s a choice between manageable functionalization and simple hydrophilicity; we recommend bromoethyl acrylate when creative chemistry and customization are needed.

    Environmental and Safety Considerations from the Plant Floor

    Over the years, environmental safety has moved to the front of our production and shipping strategy. Unlike more benign acrylates, 2-Bromoethyl Acrylate poses clear hazards for aquatic life and carries stricter transport rules. Our wastewater and air handling systems have evolved to capture trace emissions and neutralize any released brominated byproducts before they can affect the local ecosystem. We track and log all raw material and product flows—total accountability from reactor feed to packed drum is a daily expectation, not a paperwork requirement.

    On the regulatory front, we stay current with regional rules on halogenated chemicals. Our safety training for new operators runs longer when moving up to this compound, and we enforce strict zone controls to contain even minor spills. Each canister gets tracked right through to recycling or disposal, cutting off avenues for uncontrolled environmental exposure. These steps come from direct lessons learned, as well as regular third-party audits that challenge us to keep refining our routines.

    Practical Solutions and Ongoing Innovation

    Production challenges sometimes catch even seasoned chemists off guard. Early on, trace metals from cheap reactor linings catalyzed side polymerization. Investing in upgraded glass-lined reactors proved essential not only for yield but also for maintaining color and odor standards demanded by customers in healthcare and electronics. Every time we solve a manufacturing snag, we circle back to customers who pushed for a better or cleaner product—and we share what we’ve changed, encouraging feedback on every improvement.

    Our R&D lab spends as much time on storage and usability improvements as on synthesis. We test custom stabilizer systems, dosing aids, and user-friendly packaging that let users draw the compound without waste or exposure risks. One recent advance split the product line by application area, offering tighter water content control and more robust inhibitor mixes to suit either pharmaceutical synthesis or high-throughput materials labs. Our team calls customers to verify the new batch works as intended; regular dialogue identifies quirks in different reactors or application methods and drives our own incremental changes.

    In an era of digital procurement, we still sign off personally on every lot and retain a sample for cross-checking against any customer inquiry. Years of batch data, operator notes, and retention samples have solved more technical disagreements than any data sheet ever could. Our operators remember challenging lots by name and relay tips for process adjustments back to both our own technical staff and to end users—a closed loop not offered by hands-off suppliers or brokers.

    Future Directions: Meeting High Standards and Evolving Needs

    New customer requests keep appearing at our door. Sometimes a biotech startup seeks finer control of side-chain functionalization for a novel biomaterial. Other times, advanced materials developers request specialized grades with even lower impurity profiles or tighter inhibitor tolerance. We rarely turn these orders away; instead, we treat them as technical challenges to broaden our portfolio. Over time, user-driven modifications have pushed us to implement real-time data collection on every batch, automate more QC checks, and wire in environmental monitors during shipment to anticipate and prevent quality drop-off.

    We keep a sharp lookout for regulatory changes, especially in markets aiming to restrict certain halogenated intermediates. Anticipating change, we invest in cleaner synthesis, better containment, and comprehensive documentation. By reporting not just specs but traceability and handling best practices, we help customers prepare for their own audits. The partnership strengthens both process safety and the end-use reliability of what our customers build with our products.

    Building Reliability, One Batch at a Time

    Managing production, handling, and distribution of 2-Bromoethyl Acrylate is not a generic task—it calls for engagement at every stage and incorporates feedback from seasoned chemists and new users alike. Every drum and liter comes backed by real-world experience, decades of manufacturing insight, and continual adaptation to the fine details that shape top-tier performance. Our investments in process design, operator training, safety improvements, and customer support keep this versatile monomer working for scientists and producers in cutting-edge fields.

    The journey from acrylate feedstock through reaction vessels to the final, carefully stabilized product shouldn’t be invisible. We take pride in each delivered batch—and in sharing both the lessons learned and the best practices supporting constant improvement in how 2-Bromoethyl Acrylate contributes to discovery and progress across industries.