|
HS Code |
405635 |
| Iupac Name | N-(2-bromo-4-methylphenyl)acetamide |
| Cas Number | 7096-58-2 |
| Molecular Formula | C9H10BrNO |
| Molecular Weight | 228.09 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 132-134°C |
| Solubility | Slightly soluble in water, soluble in organic solvents |
| Smiles | CC(=O)NC1=CC(=C(C=C1)C)Br |
| Inchi | InChI=1S/C9H10BrNO/c1-6-3-4-8(10)7(5-6)11-9(2)12/h3-5H,1-2H3,(H,11,12) |
| Pubchem Cid | 2959306 |
As an accredited 2'-Bromo-4'-Methylacetanilide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 100g amber glass bottle with a tightly sealed cap, labeled “2'-Bromo-4'-Methylacetanilide, 99%,” featuring hazard and safety information. |
| Shipping | 2'-Bromo-4'-Methylacetanilide is shipped in tightly sealed containers to prevent moisture and contamination. The package is clearly labeled with hazard and handling information. It is transported according to relevant chemical safety regulations, typically via ground or air freight, with accompanying safety data sheets to ensure secure and compliant delivery. |
| Storage | 2'-Bromo-4'-Methylacetanilide should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and protected from moisture and direct sunlight. Use appropriate chemical storage cabinets, and ensure the compound is clearly labeled. Follow all relevant safety and handling guidelines. |
Applications of 2'-Bromo-4'-Methylacetanilide in Industrial Manufacturing2'-Bromo-4'-Methylacetanilide is a key intermediate utilized by leading manufacturers in specialized chemical synthesis. Its role is critical in advanced API production, agrochemical development, and performance dye formulation, among other targeted industries. As the producer, we maintain strict lot-to-lot traceability, analytical verification, and supply security to support complex downstream integration in each unique manufacturing environment. 1. Pharmaceutical Intermediate for Antipyretic Analgesic SynthesisThis product serves as a strategic building block for antipyretic and analgesic drug molecules, particularly in paracetamol derivatives with specialized metabolic profiles. Pharmaceutical companies source the material for use in regulated batch synthesis. Integration requires validated impurity control, established by-side reaction management, and optimized purification steps to meet finished API acceptance requirements. Manufacturers adjust scale and route based on process yield, targeted impurity specifications, and formulation type for the final dosage form. Industry compliance standards
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2. Agrochemical Synthesis—Phenoxyanilide Herbicide IntermediatesThe compound is a critical intermediate for manufacturing selective herbicides in the phenoxyanilide class, including active ingredients for rice and cereal weed control. Agrochemical formulators use it in batch and continuous synthesis requiring reaction scalability, by-product minimization, and tailored functionalization steps that influence herbicidal spectrum and field stability. Each campaign applies rigorous solvent recovery and in-process analytical monitoring to comply with global crop protection standards. Industry compliance standards
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3. High-Performance Dye & Pigment ManufacturingIn the color chemical sector, the compound serves as a coupling component for synthesizing specialty pigments and dyes, particularly for application in plastics, fibers, and coatings. Downstream users oversee oxidative or substitution coupling to ensure hue consistency and fastness. Integration into regulated processes demands control of metallic and non-metallic impurities, adherence to environmental emission regulations, and product-specific QA sampling throughout the production chain. Industry compliance standards
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4. Advanced Chemical Research and Custom SynthesisInstitutes and contract manufacturers deploy this compound as a customizable intermediate in the synthesis of novel heterocyclic scaffolds, potential pharmaceutical leads, and functionalized specialty chemicals. Researchers exploit its specific halogen-aniline positioning for regioselective functionalization. Process development prioritizes scalable purification, advanced impurity profiling, and precise documentation for intellectual property and patent filing. Industry compliance standards
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Every new batch of 2'-Bromo-4'-Methylacetanilide in our facility gets the same hands-on approach that we apply to every specialty compound we manufacture. Long before a client reviews the specification sheet or requests a sample, our chemists think through reaction routes, raw material sources, purification steps, and the practical details that keep quality high from the first kilogram to multi-ton scale. The market for brominated acetanilides has always demanded more precision than many care to admit, and after decades spent scaling up these reactions, our team knows where most products can fall short.
Our experience with halogen-substituted acetanilides goes back years. We have seen shifts in demand, from simple brominated intermediates for dye production to high-purity variants for pharmaceutical projects. 2'-Bromo-4'-Methylacetanilide stands out in this field. Some try to draw comparisons to more widely used bromo acetanilides, but that 4'-methyl substitution brings a different set of physicochemical properties. The reactivity of the aromatic ring shifts. We see it not only in the melting points and solubility, but in the way reactions run when you’re downstream in process development.
Every decision about our process for 2'-Bromo-4'-Methylacetanilide springs from years of working with clients who don’t just accept “good enough.” Physical details get checked at each stage: color, odor, crystalline form—while the industry standard focuses on a single melting point, we go further and calibrate purity with both HPLC and GC. Impurity profiles from different lots get cross-referenced, because customers in sectors like agrochemicals or pharmaceuticals cannot tolerate batch drift.
Production scale has never been about maximizing throughput at the expense of consistency. Our reactor setup can handle both moderate and larger orders, but we don’t rely on automation alone. Chemists do real-time spot testing. We send samples for third-party verification, not just internal signoff. Our analytical staff has rejected more than one batch that would have slipped past a less-experienced manufacturer. Large customers working in fine chemicals have commented more than once that our product quality has kept their own lines running when alternative sources failed.
2'-Bromo-4'-Methylacetanilide most often appears in conversations around intermediate synthesis for pharmaceuticals, dyes, and some specialty pesticides. The presence of both a bromo and a methyl group gives chemists two distinct sites for modification. In cross-coupling reactions, the ortho-bromo position enables direct functionalization, while the methyl group can alter electronic and steric effects, shifting downstream product yields. Our staff has helped more than one customer adjust process parameters after switching from generics to our product and seeing unexpected improvements in yield and reproducibility.
Certain clients order this compound for specific Suzuki-Miyaura and Buchwald–Hartwig reactions, where reactivity hinges on subtle differences in substitution patterns. Routine material from traders will contain higher residual solvents or show broad melting ranges. Purity issues like these lead to longer purification steps and unpredictable reaction results, wasting days of effort. By maintaining stringent controls and clean workups, we ensure fewer bottle-necks for customers, especially during process scale-up.
Many new clients share stories about frustrations with off-spec batches sourced elsewhere. There’s a view among bulk traders that all brominated acetanilides behave the same, but the reality looks different inside a production plant. 2'-Bromo-4'-Methylacetanilide is particularly susceptible to color changes and impurity formation if temperature profiles or pH drifts even slightly during synthesis. Customers who have received off-color, foul-smelling or partially hydrated material see exactly what happens to yield and conversion rates.
Our team refinanced our approach years ago, returning to smaller batch trials to root out the variables that plagued earlier supply chains. We learned quickly how much final utility depends on dry, free-flowing product. Moisture content may sound like a minor spec point, yet anyone who runs reliable organic synthesis knows that small amounts of water can quench sensitive reactions. We run every lot through rapid moisture analysis and maintain water content levels far below standard thresholds. Rather than focusing only on purity percentages, our QA process asks: How does this batch behave out there in the real world?
Another point worth mentioning is the particle size distribution. Not every customer discusses this at the start, but once solid handling or blending issues come up, it lands on our technical support desk. We have invested in custom milling and sieving equipment to keep granulate uniform, avoiding caking or dust clouds during formulation. That hands-on knowledge saves time for formulators and process engineers who can’t afford to troubleshoot every new batch.
Some manufacturers take a hands-off approach, shipping 2'-Bromo-4'-Methylacetanilide with no questions asked and letting the chips fall where they may. We continue to support clients long after delivery. Our technical staff regularly hosts calls with customers who run into challenges during scale-up or tech transfer. In one recent case, a client was seeing variable reaction times and inconsistent color with a generic product. We walked through their setup step by step, performed comparative testing, and isolated two minor impurities that changed reactivity just enough to cause headaches. By adjusting purification protocols on our end, we provided cleaner material. Their next production run started on time, under budget, and with none of the delays that had plagued previous campaigns.
We see the real-world effects of minor impurities play out not just in the lab but along full supply chains. If raw materials fluctuate in purity, so do throughput, waste streams, and timelines. An entire week can hinge on a reliable supply of high-quality intermediate. That’s why we treat every order not just as a transaction but as a practical partnership. As deadlines grow tighter and regulatory oversight rises, these things matter more with each passing year. We know that repeatability and transparency build trust, batch after batch.
Manufacturing 2'-Bromo-4'-Methylacetanilide has pushed us to pay closer attention to both regulatory compliance and environmental footprints. Local agencies keep raising the bar on waste disposal and emissions, particularly with halogenated compounds. Years ago, byproduct management barely registered as a talking point. Now, detailed cradle-to-gate data and closed-loop solvent recovery systems shape every discussion with clients. We track all precursor origins and share material traceability reports as part of our standard practice.
Operators conduct safety checks before and after each run, monitoring for byproduct fumes. Not every plant has invested in exhaust abatement at our level—scrubbing and neutralizing air streams before release keeps our impact low and ensures regulatory sign-offs come without last-minute surprises. Customers ask for more than just certificates of analysis now. Auditors visit plants, review process controls, and demand waste manifests before approving a new supplier. Our staff welcomes these changes because safer, more transparent operations help both our neighbors and clients sleep a little better.
Sustainability goes beyond “reduced footprint” slogans. Bromine supplies can be a pinch point for global supply chains, and volatility in sourcing affects pricing and availability. For several years we have invested in raw material audits and alternate sourcing pathways. Process engineers constantly discuss ways to cut solvent volumes, optimize energy use, and recycle wherever practical. We chose high-efficiency reactors on our last plant expansion—and now share usage data openly with clients who ask for a detailed look at our footprint.
Over many years, every setback, return, and urgent order has fed back into our process. We never quite “arrive”—and don’t expect to. After bringing on new hires from both industrial and academic backgrounds, we started cross-training chemists on QA, logistics, and analytical reviewing. Some of our best improvements have come from those who noticed patterns others missed, such as slight shifts in crystal habit under different cooling profiles or the benefits of altered agitation speeds for better yield. Open feedback is the norm here; no one gets stuck repeating old mistakes.
The collective pride in a tough product like 2'-Bromo-4'-Methylacetanilide comes from problem solving together. There’s no shortcut to the kind of skill built through dozens of production cycles, troubleshooting both the common headaches—solid clumping, endpoint ambiguities, color drift—and the rare, compound-specific quirks that catch only the most attentive operators. We encourage lab techs to track anomalies with detailed logs and run regular debriefs. Patterns get flagged, debated, and resolved upstream so every order maintains our hard-won standards.
Customers usually show up with a checklist: physical specs, purity, documentation, cost. After a few weeks or months, feedback changes. They begin to notice shorter setup times and fewer product-related anomalies in their downstream processing. Better lot traceability allows their own QA teams to streamline reporting to their regulatory partners. Rush orders get filled without drama—they value not just the product, but the reliability and real-time support that comes with it.
Several customers who originally sourced 2'-Bromo-4'-Methylacetanilide outside our plant have switched over to us and stayed for years. They have cited close attention to lot consistency, cleaner impurity profiles, and robust documentation as the most important differences. In fast-moving industries with shifting specifications and regulatory scrutiny, these details count far more than most outsiders realize. Our reputation grows batch by batch, driven by a simple goal: help our partners do their work better, faster, and with less hassle.
Experience has taught us that manufacturing is rarely about one-off orders or commodity pricing wars. It’s about earning trust through results, communication, and mutual respect. Every customer’s needs change over time. Some years later, a company that once bought small research lots of 2'-Bromo-4'-Methylacetanilide returns needing commercial-scale volumes. Other times, a new regulatory challenge or an unexpected impurity requires rapid technical support and a few late-night calls with our team.
We think about the entire lifecycle of each product—from ordered raw material through documented shipment—not as isolated steps, but as parts of a working partnership. Our team knows the downstream risk if any detail goes unchecked. That’s why we maintain open books, rigorous analytical work, and an on-call technical team whose job is to help solve problems as they come. Few things matter more to us than the trust our clients place in our production process and quality systems.
The methods and controls that set our 2'-Bromo-4'-Methylacetanilide apart have come from hard experience and regular dialogue with scientists and engineers on the front lines. Our facility doesn’t chase commodity niches, nor do we rest on autopilot, banking on old process protocols. We see every new project as an opportunity to advance both our product quality and customer satisfaction.
New developments in process chemistry, green manufacturing, and automation shape how we think about future batches. We stay in close contact with end users to keep up with their evolving requirements, whether those involve reagent compatibility or environmental documentation. Change is a given—our mission is to anticipate the details that matter and deliver on them before they become a problem.
Working directly with the manufacturer brings perspectives and quality safeguards that third-party traders and resellers cannot replicate. Information flows both ways. Clients describe new application spaces and unique process needs. We respond with process adjustments, custom packaging, and hands-on technical input. Our product goes straight from our controlled environment to the customer, minimizing third-party surprises or handling errors that can disrupt sensitive operations.
We measure our success in continued repeat orders, unprompted customer referrals, and tangible improvements in our clients’ workflow. Long-term partnerships don’t happen overnight. They reflect daily attention to small details, commitment to open communication, and a willingness to put expertise to work solving real-world problems. For those in need of 2'-Bromo-4'-Methylacetanilide that performs to the highest standards, the difference made by an experienced and transparent manufacturer becomes clear, shipment after shipment.
There’s no magic trick for making specialty chemicals like 2'-Bromo-4'-Methylacetanilide succeed in demanding applications. It takes skill, vigilance, and a readiness to confront issues head-on. We have learned that customers value not just a good product, but the support and experience behind it. Our team carries that responsibility every day, and we look forward to building better, smarter ways to serve the markets that rely on us.