Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Bromo-2-Methylbutane

    • Product Name 2-Bromo-2-Methylbutane
    • Alias tert-Amyl bromide
    • Einecs 202-691-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    265641

    Iupac Name 2-Bromo-2-methylbutane
    Molecular Formula C5H11Br
    Molar Mass 151.05 g/mol
    Cas Number 594-18-3
    Appearance Colorless liquid
    Density 1.197 g/cm³
    Boiling Point 91-93 °C
    Melting Point -102 °C
    Refractive Index 1.432
    Flash Point 12 °C
    Solubility In Water Insoluble
    Odor Characteristic halogenated odor

    As an accredited 2-Bromo-2-Methylbutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 mL of 2-Bromo-2-Methylbutane, sealed with a secure cap, labeled with hazard and identification information.
    Shipping 2-Bromo-2-methylbutane is shipped in tightly sealed containers, typically amber glass bottles or high-density polyethylene containers, to prevent leakage and protect from light. It is classified as a hazardous material and must be labeled accordingly. Shipping must comply with local, national, and international regulations for flammable and potentially harmful chemicals.
    Storage 2-Bromo-2-methylbutane should be stored in a tightly closed container in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Keep it out of direct sunlight and sources of ignition. Use secondary containment to prevent leaks or spills. Label containers clearly and ensure storage areas are equipped with appropriate spill containment and fire-fighting equipment.
    Application of 2-Bromo-2-Methylbutane

    Applications of 2-Bromo-2-Methylbutane in Industrial Manufacturing

    2-Bromo-2-Methylbutane serves as a critical intermediate in numerous fine chemical and specialty chemical processes. Its controlled reactivity and defined structure make it suitable for advanced synthesis in several industrial sectors. As a direct manufacturer, we supply this material in bulk for integration into validated downstream operations.

    1. Pharmaceutical Intermediate Synthesis

    Integrators in API production use 2-Bromo-2-Methylbutane as an alkylating agent to introduce branched side chains in the synthesis of antihypertensive and antiarrhythmic drug precursors. Its secondary alkyl bromide functionality supports the preparation of pharmaceutical scaffolds via nucleophilic substitution steps under controlled laboratory and industrial settings. Quality assurance relies upon batch traceability and compliance with cGMP protocols established in the regulated pharmaceutical supply chain.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA Title 21 CFR Parts 210 and 211
    • European Pharmacopeia (Ph. Eur.) General Notices for Synthesis Intermediates
    • China Pharmaceutical GMP (2020 Revision)

    Typical usage ratio

    • 0.9–1.3 molar equivalents relative to nucleophile used, adjusted for process yield

    Downstream process integration

    • Added in the alkylation stage following core heterocycle construction
    • Charged in batch or semi-continuous reactors under inert atmosphere
    • Controlled temperature (10–40°C) to minimize side reactions
    • Monitored via in-line HPLC for conversion check

    Final product types

    • Branched-chain antihypertensive drug actives
    • Antiarrhythmic API intermediates
    • Specialty pharmaceutical building blocks
    • Custom research chemicals for contract drug development

    2. Agrochemical Intermediate Manufacturing

    Producers of selective herbicides and growth regulators integrate 2-Bromo-2-Methylbutane to yield specific branched carbon skeletons via nucleophilic substitution or elimination methodologies. The material provides a reliable feedstock for constructing active molecules that require strict isomeric control and high conversion efficiency in subsequent synthetic steps.

    Industry compliance standards

    • FAO/WHO Technical Guidelines for Agrochemical Intermediates
    • ISO 9001:2015 Certified Facility Requirements
    • Chinese National Standard GB 15319 for Pesticide Production
    • REACH Regulation (EC) No 1907/2006 for Precursor Registration

    Typical usage ratio

    • 0.8–1.1 molar equivalents per synthesis, based on downstream reactivity and purity

    Downstream process integration

    • Alkylation or elimination step after aromatic base construction
    • Solvent selection (e.g., DMF, acetonitrile) determined by target molecule
    • QC through GC-MS analysis for residual bromide and side products
    • Process adjustment for scale-up using pilot batch data

    Final product types

    • Selective herbicide intermediates
    • Plant growth regulator synthesis blocks
    • Branched-chain insecticide precursors
    • Novel active ingredient prototypes for field trial batches

    3. Odorant and Fragrance Chemical Synthesis

    Fine fragrance manufacturers use 2-Bromo-2-Methylbutane as a key alkylating agent to create branched aliphatic compounds for use in aroma molecules. Its use enables the targeted construction of intermediates that ultimately display desirable volatility and olfactory persistence in personal care product formulations.

    Industry compliance standards

    • IFRA Code of Practice Compliance
    • EU Cosmetics Regulation (EC) No 1223/2009 for Ingredient Safety
    • ISO 22716:2007 Cosmetic GMP
    • REACH Pre-manufacture Notice for Allergenic Assessment

    Typical usage ratio

    • 1.0–1.2 equivalents per derived intermediate batch, adjusted by yield and sensory profile testing

    Downstream process integration

    • Reacted via nucleophilic substitution with core tertiary alcohols or aromatic rings
    • Critical for side-chain attachment in late-stage modification
    • Process monitored by GC for profile consistency
    • Final purification by distillation or liquid-liquid extraction

    Final product types

    • Branched aliphatic alcohols for fragrance compounds
    • Bases for musk and amber notes
    • Odorant intermediates for fine perfumery
    • Flavoring ingredients for personal care products

    4. Polymer and Resin Functionalization

    Specialty polymer producers utilize 2-Bromo-2-Methylbutane as a functionalization reagent to introduce reactive alkyl groups into polymeric chains during surface treatment or copolymer synthesis. The material supports the preparation of tailor-made resins with enhanced adhesion, flexibility, or compatibilizing properties for use in advanced coatings and adhesives.

    Industry compliance standards

    • US EPA TSCA Chemical Substance Inventory
    • EU Regulation (EC) No 1272/2008 CLP for Safe Handling
    • ISO 14001:2015 Environmental Management
    • Chinese GB/T 19001-2016/ISO 9001 Quality Management

    Typical usage ratio

    • 5–20 wt% of functional monomer feed, depending on targeted resin properties and end-use application

    Downstream process integration

    • Introduced during monomer mixing or chain transfer step in emulsion polymerization
    • Reacts in situ during copolymer synthesis under thermal or UV-initiated conditions
    • QC includes molecular weight distribution and residual bromine analysis
    • Resin performance tested for adhesion and mechanical strength

    Final product types

    • Acrylic copolymer resins for high-performance coatings
    • Specialty adhesives for automotive and electronics assemblies
    • Modified polyolefin for flexible films
    • Reactive plasticizers and compatibilizer agents

    5. Organic Synthesis and Contract Manufacturing

    Custom synthesis providers and fine chemical manufacturers use 2-Bromo-2-Methylbutane as a versatile starting material or intermediate in complex multi-step synthesis. Applications include the preparation of specialty ligands, catalysts, and high-purity reference compounds, where controlled introduction of branched alkyl groups is necessary for achieving target molecular architecture.

    Industry compliance standards

    • ISO 17025 Laboratory Accreditation for Analytical Consistency
    • REACH Registration for Bulk Import/Export
    • Responsible Care® Program Certification
    • Custom QC protocols validated per contract specification

    Typical usage ratio

    • 0.95–1.5 equivalents per custom synthesis step, as determined by stoichiometry requirements and conversion rates

    Downstream process integration

    • Applied during key alkylation or substitution stages following core scaffold assembly
    • Used under inert conditions with real-time reaction monitoring for side product control
    • Integrated into process route development for scalability and process safety
    • Pilot-scale production adheres to technical transfer documentation for repeatability

    Final product types

    • Specialty ligands for homogeneous catalysis
    • Custom organometallic reagents
    • Analytical standards and high-purity reference materials
    • Life science intermediates for research and pilot batches
    Free Quote

    Competitive 2-Bromo-2-Methylbutane prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 2-Bromo-2-Methylbutane: A Manufacturer’s Perspective

    Overview from Years in Chemical Manufacturing

    Our journey with 2-Bromo-2-Methylbutane tracks back decades, not as resellers trading spreadsheets, but as hands-on chemists and plant operators observing the pulse of each batch. In a field where minor compositional quirks can stall entire processes, clarity about what we make matters. Our 2-Bromo-2-Methylbutane, also known in shorthand as tert-amyl bromide, provides a straightforward profile: clear, colorless liquid, rich in reactivity and ready for demanding synthesis. We’ve spent years refining its preparation, targeting purity that answers not just to in-house tests but also to the strict benchmarks of pharmaceutical and agrochemical producers who rely on precise building blocks.

    Understanding the Product and Its Specifications

    Our production centers around feedback from the folks who rely on us. Analytical chemists want less speculation, more detail: clear GC traces, minimal byproducts, batch-to-batch reproducibility. With 2-Bromo-2-Methylbutane, we approach every run with the same focus. We manufacture and package under ISO-certified controls, running frequent in-process checks to keep the product at or above 99% purity. Water, halogenated traces, and heavy metal contents undergo daily scrutiny. We keep NMR and GC-MS audits available for trace analysis. For surface-level product listings, this may sound like excess, but on the receiving end, our clients report smoother downstream purification and reliable reaction yields that translate to cost and schedule certainty.

    Practical Use and Insights from the Field

    2-Bromo-2-Methylbutane rarely stands alone on shelves. It’s a familiar face on benches where alkylation reactions fuel a range of industry workflows—from research teams designing new CNS-active agents to full-scale production facilities crafting crop-protection intermediates. As an alkylating agent, it brings bulk and branching, giving rise to tertiary carbon centers—no small feat for those building more intricate molecules. Whether the end-use involves nucleophilic substitution under mild conditions or in the presence of competing nucleophiles, users appreciate its ability to forge robust C–C and C–N bonds with agility. Time and again, teams working on route optimization highlight how our product’s low impurity content diminishes side reactions, saves chromatography time, and tightens the margin between theory and actual yield.

    Beyond Commodity: Why Source Matters

    Many think of bromoalkanes as basic reagents, easy to find. In reality, subtle differences can trouble both research and scale-ups. Less refined versions carry shadow isomers, leftover catalysts, or residual moisture—factors that complicate reaction monitoring and lower product confidence. We have seen cases where uncontrolled storage invariable causes yellowing or slow decomposition, triggering batch failures upstream. Our approach limits light and air exposure well before shipment, with tamper-evident closures and inert-gas blanketing as standard. It keeps our product stable not just on arrival, but through prolonged storage, so chemists aren’t left adjusting for batch-to-batch quirks.

    Addressing the Safety and Handling Question

    Direct involvement on the factory floor teaches respect for both the product and those who use it. Alkyl bromides don’t reward careless handling—they bring acute irritation risks, so we stress real-world precautions in addition to the paperwork. Years of working around such compounds built a culture here of education: real human stories, not just label warnings. Clear packaging, secondary containment, and employee PPE audits at our facilities help set expectations for safe transit and use downstream. We also listen to customer reports of bottlenecks—from fume hood mist to temporary storage protocols—to keep evolving our containers and advice. These aren’t just bolt-on features; they are responses to hard-learned lessons in minimizing both environmental releases and personnel exposure.

    Why Users Keep Returning to Our 2-Bromo-2-Methylbutane

    Repeat customers drive progress around here and their R&D headaches often inform our process tweaks. Many surface-level suppliers tout competitive pricing, but our clients know the hidden costs in yield drops and troubleshooting. We invest in real communication, backing every container with access to chemists who know the route and infrastructure inside out. We’ve helped troubleshoot everything from inconsistent color to unexpected gas evolution, frequently tracing these issues back to impurities that less vigilant suppliers let slide. This feedback loop lets us optimize our plant and supports confident, repeatable outcomes in labs and production lines far outside our own walls.

    Comparing to Other Tertiary Alkylating Agents

    Chemists often weigh 2-Bromo-2-Methylbutane against tert-butyl bromide, tert-pentyl chloride, or even non-halogenated alternatives. The differences are more than academic—one brings reactivity tempered by sterics, another by volatility, and each carries its own set of side reactions. In practice, 2-Bromo-2-Methylbutane carves out advantages with its combination of moderate boiling point, solid shelf-stability, and the ability to influence regioselectivity in synthesis. Some labs prefer the alternative tert-butyl bromide for raw speed, but the added methyl group on 2-Bromo-2-Methylbutane makes for bulkier, more highly branched products and less unwanted rearrangement. In large-scale alkylations, where loss and contamination add up, our higher purity means users aren’t fighting with hydrolysis or chasing down decomposed residues.

    Traceability and Documentation Built from Experience

    We’ve always found that buyers value more than the drum and label; they want a partner who can map each batch back to a full data trail. Each lot carries documented provenance from raw material intake through to finished product. Operational data, batch analytics, and audit logs are kept up to date—not to pad compliance, but to troubleshoot rare issues with confidence. Customers from regulated sectors—pharma, flavors and fragrances, advanced polymers—draw real value from this transparency, often incorporating our certificates of analysis into their internal QMS records and regulatory filings. If trace issues arise, we can respond quickly because our own operators keep one foot in the lab and the other in the ledger.

    Tackling Waste and Environmental Responsibility

    Solvent and halide waste management remains a real test in our industry. Overproduction and rapid delivery tend to shift environmental priorities to the back burner, but we maintain closed-loop practices for both containment and recycling. Distillation residues and wash streams receive in-house treatment to prevent load on community resources and local waterways. Newer investments in VOC abatement and solvent recovery have reduced off-air losses and disposal volumes year over year. Regulatory landscapes keep shifting, but as a manufacturer we’ve found that robust compliance opens doors to global markets—and gives buyers confidence that what they source won’t come back to haunt their own ESG metrics.

    Process Tweaks Informed by End-User Feedback

    Every batch run in our plant is a collaboration with the broader scientific community. Our engineers sit down not just with raw specs, but with shared notebooks and field reports. Pharmaceutical chemists demand consistency; agrochemical scale-ups stress on-time delivery with zero surprises. We adapt procedures to minimize color, odor, and impurity drift, reading between the lines of client complaints and wish-lists. When issues surface—like rare halide carryover or moisture spikes—operators feed the experience back into process controls, not just paperwork. Direct calls to our technical team spark more experiments and lead to safer, more robust procedures, closing the gap between small-batch theory and commercial flow.

    Global Distribution and Supply Confidence

    As sourcing standards rise, guarantee of supply amounts to more than just transport logistics. Sudden global events, regulation shifts, or local bottlenecks disrupt too many projects unnecessarily. We address this with both domestic and international stockholding, strategically sited warehouses, and robust supply agreements that prioritize ongoing partnerships over once-off sales. Clients enduring border clearance delays, customs regulatory changes, or container shortages count on us for real-time updates and proactive contingency planning. Our presence at regional sites makes it easier to pivot as needed, cutting down risk and providing a buffer against supply-chain noise.

    Innovation Drives the Next Generation of 2-Bromo-2-Methylbutane

    The chemistry toolbox keeps advancing, and demands for greater selectivity and environmental profile drive our internal R&D. Tighter process controls and more effective greener-by-design production routes move us away from legacy halogen handling, with newer catalysts and solvent systems under active development. Customer projects often seed these innovations: for example, several collaborations with medicinal chemists have led us to retool trace metals filtration and reduce energy footprint in batch operations. As more industries ask for lifecycle data, we keep refining both our product and the means behind it.

    How Product Quality Impacts Downstream Workflows

    Reproducible synthesis relies on each component doing its job without unknowns muddying the waters. With 2-Bromo-2-Methylbutane, high purity translates directly to less rework and troubleshooting at the bench. In high-stakes settings like pharma API research or fine fragrance intermediates, even trace contaminants can wreck a project’s timeline, not to mention regulatory headaches. By leaning on high-throughput analytics and historical trend data, our team can adjust for shifts in feedstock or process variabilities before they ripple down to the customer. Long-standing clients often cite this level of quality control as their reason for sticking with our supply, despite aggressive pushes from competitors.

    Differences Between 2-Bromo-2-Methylbutane and Similar Chemicals

    Life in manufacturing teaches you the nuances between similar alkyl bromides. For instance, tert-butyl bromide is quicker to react but leaves a different carbon skeleton in place. Slight changes in mass, distribution of electronic density, and leaving group potential collectively influence downstream chemistry. Some plants choose tert-pentyl chloride for cost savings alone, but those familiar with organic synthesis know chlorine’s weaker leaving ability brings added risk of elimination reactions and low yield. Our 2-Bromo-2-Methylbutane sits in a Goldilocks zone, giving precise control without many side products. The clean, sharp endpoint in nucleophilic substitution marks a real step up from lower-grade, mixed isomer alkyl bromides encountered in some supply chains.

    Continuous Improvements: An Open Conversation

    Our conversations seldom end at the point of sale. We host ongoing dialogues with customers—sometimes solving issues unrelated to our product, such as general process troubleshooting or adapting packing sizes to evolving plant needs. This willingness to learn both ways is woven into our standard operating procedure. Customer-led audits, internal quality reviews, and joint R&D sessions feed directly back into better procedures. Some improvements, like container upgrades or updated MSDS documents, came directly from feedback regarding their use and handling in far-off facilities. We view every interaction as a test case for building the world’s most dependable source for specialized intermediates.

    Stories from Partnered Laboratories and Plants

    Stories filter in from users whose protocols once stalled from off-color reaction masses or erratic phase separation. More than a few labs recall days lost to purifying by-flavored solvent residues from rough-cut bromoalkanes. With our streamlined 2-Bromo-2-Methylbutane, chemists report more robust alkylation chemistry, fewer unexpected spots on TLC plates, and less uncertainty about what’s lurking in the flask. One large-scale pharma synthesis team broke through bottlenecks caused by competing elimination pathways with our material; only through real-time technical discussions and open access to batch documentation did adjustments come together. We value those stories as much as any metric.

    Looking Forward: Meeting Tomorrow’s Demands

    Every calendar year brings new requirements and tighter demands on suppliers—some imposed by changing markets, others by regulators, and many by users determined to optimize their own productivity. Our product development roadmap bends in response. We keep updating our internal benchmarks based on both technical literature and real customer input, folding in more rigorous third-party testing and faster turnaround on custom specifications. Our engineers monitor not just product output, but everything from employee safety stats to customer-reported issues and anticipated market shifts.

    In Conclusion: The Manufacturer’s Promise

    Real-world chemical manufacturing isn’t just about hitting numbers on a spreadsheet. It's about knowing how a clear, colorless reagent made here supports projects around the world—and about answering the call when something needs to change. In every drum of 2-Bromo-2-Methylbutane we send out, our team stakes a reputation built over years of focused experience, steady learning, and mutual respect with the scientific community. For those on the other end, that means a product as dependable as the people making it—supported by facts, handled with accountability, and evolved by listening to every lab and plant it touches.