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2-Aminophenol-4-Sulfonmethylamide

    • Product Name 2-Aminophenol-4-Sulfonmethylamide
    • Alias Sulfanilamide
    • Einecs 241-435-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    729178

    Chemical Name 2-Aminophenol-4-Sulfonmethylamide
    Molecular Formula C7H10N2O3S
    Molecular Weight 202.23 g/mol
    Appearance White to off-white solid
    Solubility Soluble in water
    Melting Point 170-174°C
    Purity Typically >98%
    Storage Temperature Store at 2-8°C
    Cas Number 98-41-9
    Boiling Point Decomposes before boiling
    Synonyms 2-Amino-4-sulfonmethylaminophenol
    Stability Stable under recommended storage conditions
    Usage For research and laboratory use only

    As an accredited 2-Aminophenol-4-Sulfonmethylamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sealed in a 25g amber glass bottle with a secure screw cap, labeled with chemical name, hazard symbols, and batch details.
    Shipping 2-Aminophenol-4-Sulfonmethylamide is shipped in tightly sealed containers to prevent moisture and contamination. It is labeled according to chemical safety regulations, and shipped as a non-hazardous chemical unless otherwise specified. Handling precautions and Safety Data Sheet (SDS) accompany each shipment. Store and transport in a cool, dry, and well-ventilated area.
    Storage 2-Aminophenol-4-sulfonmethylamide should be stored in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and acids. Keep the container tightly closed and protected from moisture and light. Use appropriate chemical storage cabinets if possible. Ensure proper labeling and restrict access to authorized personnel. Follow local regulations and safety protocols for handling and storage.
    Application of 2-Aminophenol-4-Sulfonmethylamide

    Applications of 2-Aminophenol-4-Sulfonmethylamide in Industrial Manufacturing

    As a specialized manufacturer of 2-Aminophenol-4-Sulfonmethylamide, we supply this intermediate to key industrial sectors where chemical consistency and process reliability are essential. Below, we provide a detailed analysis of established downstream application tracks, highlighting regulatory frameworks, common incorporation levels, integration points, and representative end products.

    1. Synthesis of Azo Dyes for Textiles

    This compound serves as a specific diazo component in the manufacture of water-soluble azo dyes for cellulosic and protein fibers. Its sulfonamide substituent enhances dye solubility and fixation. During dye coupling, formulators dose the material precisely based on molar ratios with coupling partners. Consistency in purity and particle size supports batch-to-batch color reproducibility and high-throughput operations in continuous dyeing lines.

    Industry compliance standards

    • OEKO-TEX® Standard 100 Annex 6 (dyestuff criteria for textiles)
    • EU REACH Regulation (EC) No 1907/2006
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals – Manufacturing Restricted Substances List)
    • ISO 9001:2015 (Quality Management Systems in chemical processing)

    Typical usage ratio

    • 0.5–3.0% w/w on fabric weight, adjusted based on chromophore depth and desired washing fastness; exact concentration tailored to fiber reactivity and batch volume.

    Downstream process integration

    • Added to the diazotization vessel, reacted in aqueous phase under controlled pH with sodium nitrite, then coupled directly onto textile fiber or as a dye intermediate for further sulfonation or metal complexation.

    Final product types

    • Direct dyes for cellulosic fabrics
    • Azoic dye intermediates for print pastes
    • Reactive dyes for wool and silk
    • Dyed cotton and blended yarns

    2. Intermediate for Sulfonamide Pharmaceuticals

    Pharmaceutical producers incorporate this raw material in the synthesis of advanced sulfa drug molecules. The aminophenol backbone enables precise biotransformations, while the sulfonmethylamide moiety confers water solubility and bioactive selectivity. Process engineers manage feed rates and reaction conditions to ensure purity for subsequent condensation and cyclization, critical for GMP-compliant supply chains.

    Industry compliance standards

    • USP–NF (United States Pharmacopeia – National Formulary)
    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • China Pharmacopoeia (ChP)
    • EU GMP Part II (Active substances production)

    Typical usage ratio

    • 0.3–1.2 molar equivalents as starting material, adjusted to targeted molecular transformations during multistep API synthesis.

    Downstream process integration

    • Charged into stepwise batch reactors for condensation or nucleophilic substitution; subsequent purification steps align with validated pharmaceutical process routes.

    Final product types

    • Sulfonamide antibacterial agents
    • API intermediates for anti-infectives
    • Sulfa-containing co-crystals
    • Biosimilar drug synthesis

    3. Metal Complexing Agent for Water Treatment Chemicals

    2-Aminophenol-4-Sulfonmethylamide provides a chelating locus for custom synthesizing water-soluble complexing agents. These agents target iron and manganese removal in water purification systems. Industrial formulators utilize its specific amine and sulfonamide configuration for designing ligands with controlled pH stability and minimal residual interference, supporting environmentally compliant water treatment solutions.

    Industry compliance standards

    • ANSI/NSF 60 (Drinking Water Treatment Chemicals—Health Effects)
    • EN 15077:2006 (Chemicals used for treatment of water intended for human consumption)
    • ISO 14001:2015 (Environmental Management in production)
    • RoHS Directive 2011/65/EU (limits for use in EU markets)

    Typical usage ratio

    • 0.8–2.5% w/v in formulated chelating blends; exact amounts determined through jar-test optimization relative to target metal ion loads.

    Downstream process integration

    • Introduced during the formulation of liquid or powder additives; complexation typically occurs in-line, prior to dosing into municipal or industrial water streams.

    Final product types

    • Iron removal agents
    • Manganese sequestering blends
    • Precipitation inhibitors for cooling water systems
    • Potable water purification additives

    4. Photographic Chemical Manufacturing

    Producers of photographic developers and stabilizers rely on this specialty intermediate as a reducing and complexing agent. Its molecular profile supports fine-grain developing of silver halide films. Strict quality assurance and particle control are vital to avoid streaking or fogging in high-resolution photographic output. In process, compound addition rates are verified by spectroscopic monitoring and standardized against batch developer recipes.

    Industry compliance standards

    • ISO 9001:2015 (Quality management for photographic chemicals)
    • ISO 18911:2010 (Photographic activity test - developer stability)
    • EU CLP Regulation (EC No 1272/2008; chemical labeling for photographic chemicals)
    • Japanese Industrial Standard (JIS K7624 - chemicals for photographic processing)

    Typical usage ratio

    • 1.0–6.5 g/L within photographic developer solutions; rates governed by film type and development kinetics.

    Downstream process integration

    • Dissolved directly into aqueous developer concentrates during batch makeup; routinely filtered prior to filling to prevent particulates in emulsion processing.

    Final product types

    • Black and white film developers
    • Silver halide stabilizers for imaging paper
    • Photofinishing bath additives
    • Laboratory X-ray plate processing kits
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    Certification & Compliance
    More Introduction

    2-Aminophenol-4-Sulfonmethylamide: Experience from the Source

    Our Perspective as a Producer

    Factories never pause, and neither do the needs of our partners. In manufacturing 2-Aminophenol-4-Sulfonmethylamide, we have learned that every batch tells a story—created for real demand, tested through practice, and judged by actual performance. This product arises from decades spent watching chemicals leave our gates and return as finished goods from customers, often transformed into items used daily across the globe.

    Product Character and Specifications

    We produce 2-Aminophenol-4-Sulfonmethylamide as a free-flowing powder, pale to light brown in color. In customer’s hands, that visible trait translates to peace of mind about purity and ease of handling. Laboratories report reliable assay results, thanks to our process controls that keep active content within a narrow window. It’s easy to overlook the importance of stable moisture levels until you’ve seen what fluctuations can do to yield and process downstream. Our moisture readings stay low and steady, and the product’s melting profile lands where technicians expect, with minimal deviation from batch to batch.

    From years at the reactor controls, we’ve recognized recurrent concerns: inconsistent solubility or unpredictable performance in later synthesis steps. We’ve tuned our washing and drying stages to address this. The attention here means customers report fewer losses and less need for extra downstream adjustments. When customers need detailed analytical data, we open our records, from HPLC chromatograms to trace inorganic impurities. Nobody’s surprised by outliers—scrupulous internal checks see those caught before the product leaves the plant floor.

    Unpacking the Chemical’s Role in Application

    2-Aminophenol-4-Sulfonmethylamide does substantial work in organic synthesis. The compound’s amine and sulfonamide groups give it versatility. Our partners in dye manufacturing use it as a coupling component, reporting brighter shades in azo dye intermediates. When the process asks for consistency, any deviation can upset the shade or reduce batch yield. We keep discussions open with dye chemists, listening when one batch performs better or lasting longer in light- and wet-fastness tests. Each story feeds back into how we purify and dry the material.

    In pharmaceuticals, the compound finds use as an intermediate. Chemists trust it for developing molecules where purity sets the project up for regulatory review. Small differences in trace metal content or identity impurities make the difference between progress and a roadblock. Time and time again, we see projects move forward more smoothly when researchers get a straight answer about what’s in each drum. As manufacturers, we stay in touch with researchers in fast-moving fields, sharing updates when we’ve cut a process impurity or improved filtration. That channel of information works both ways.

    The material also plays a supporting role in the agricultural sector, entering the synthesis of active substances for crop protection. Plant scientists grapple with increasingly complex regulatory limits on trace residues and byproducts. We’ve learned not to trim close to the limits—delivering a slightly purer material costs a little more, but nobody wants to go back and trace a failed registration to a process shortcut.

    Quality Commitment Grown from Experience

    We’ve seen less precise versions of this chemical on the market. These tend to create headaches downstream, from slow reaction rates to appearance of colored specks in finished dyes. Customers bring us real samples of failures—batches that crystallized with the wrong hue, powders that clumped and failed to disperse, or filtrations that dragged on for hours. We tackle those problems not with formulaic answers, but by retracing each step in our plant and in their test run. That way, the next shipment avoids the same trouble.

    We take in waste streams and side fractions, monitor pH drift, and manage trace sulfur transfers. These steps aren’t just about box-checking, but because every small slip leads to a visible change: a delayed reaction, a different odor, or a batch that doesn’t quite match the reference. Every chemist in our facility understands what small impurities mean downstream. It isn’t enough to produce to a generic “industry standard” when partners rely on each lot for their reproducible results.

    Testing happens batch by batch, and we store retains longer than required. If something goes sideways in the field, we invite those who found the problem to our plant. Blade-to-batch, we run comparisons so everyone understands exactly where the issue started. We also learn plenty from these calls—sometimes, subtle feedback about crystal habit or particle size has led us to swap filtration media, or to tweak a crystallization endpoint that we’d once considered “good enough.”

    What Sets Our Production Apart

    Our 2-Aminophenol-4-Sulfonmethylamide stands out for consistency in parameters customers actually track. Experienced dye manufacturers and pharma process heads notice fewer batch failures and less re-testing. Our customers report the dusting properties make automated handling more reliable. Drums pass through handling lines without the caking or static that’s more frequent from some competitors’ versions. This comes from direct feedback and tweaks to our drying and packaging: changing anti-caking agents carries real-world effects, and our adjustments come from field trials, not just lab-table ideas.

    The main difference with alternative products usually starts with the origin of raw materials. We source in-house and avoid unidentified recycled feed, which brings benefits in low trace contaminants and batch-to-batch color uniformity. In some markets, suppliers cut steps and send partially purified or overheated material. That saves costs, but past buyers have called us with stories of hidden fines, off-odors, and unexpected melt points. These headaches get traced directly to shortcuts upstream. By keeping controls tight, we’ve eliminated customer reports of “drum-to-drum” variability—the kind that leaves procurement teams searching for which batch to trust.

    Product differences also show up in shipping. We’ve sent drums across continents, responding to concerns about temperature, humidity, and long warehouse waits. Our packaging evolved after we witnessed condensation issues firsthand at a customer port. Now every shipment is lined, sealed, and double-checked, not just as a matter of form, but because we’ve seen what happens in less robust packaging. These aren’t abstract concerns, but lessons learned after shipments sat too long in tropical warehouses and product quality suffered.

    Knowledge from Continuous Improvement

    Feedback, field trials, and close collaboration with users have shaped every improvement. Once, pigment manufacturers flagged slow reaction rates and traced the cause back to minute byproducts. We responded by installing new purification sequences. Dye-makers wanted lower moisture, not just for regulatory paperwork but because of actual effects on the shade of finished goods. We invested in better vacuum dryers and routinely check every output for changes. Anything that dips outside pre-agreed criteria brings production to a halt, followed by a deep-dive into process logs and real-time adjustments.

    Keeping the door open to customers and university researchers, we regularly review market requirements and new findings. If a new impurity is detected out in the field, or fresh analytical methods reveal something unexpected, we don’t shy away from updating our procedures. Backing chemical quality is not just about ticking regulatory boxes. Each iteration often comes from direct customer reports, raw material upgrades, or tighter lab measures. We also absorb lessons from suppliers: raw input variation is checked early, minimizing unexpected surprises in finished goods.

    Direct Dialogue with Users

    Customers regularly ask what differentiates one producer’s material from another’s, and we always return to lineage and openness. Knowing where every gram comes from—what reactor line, which shift, every raw material driver—gives our partners more than test certificates. They trust the hands on the valves and the eyes on QC screens. No truckload leaves without double-data: we match shipping logs, batch data, and on-site lab results to the field’s actual needs. Sometimes, lots sold under the same grade differ sharply depending on source, prompting in-depth troubleshooting that we’re always willing to join.

    We aim to demystify unexpected results. A batch that fails in a customer’s hands receives our full attention. We run matching experiments, simulate process conditions, and adjust if we find a better way. This spirit of partnership—going beyond the sale—sets a standard for what customers should expect from chemical producers. Shared experience is at the foundation: customer chemists bring decades in their trade, and our input grows from similar years spent troubleshooting, adjusting tanks, and monitoring shifts under every kind of pressure.

    Staying Ahead of Regulatory and Market Shifts

    Increasingly strict regulatory standards globally have forced chemical manufacturers to think beyond pure analysis tables. We’ve adapted regular auditing, traceability procedures, and track evolving registration lists. When new country regulations or global treaties change accepted impurity levels, our process shifts in sync, often ahead of compliance deadlines. This isn’t just preparation—it keeps new market entries smooth for our partners, letting them focus on process or formulation advantages instead of supply interruptions. Anyone who has gone through sudden customs holds or import notices from regulatory updates knows the value of a supplier already prepared.

    We stay connected with working groups and keep a watch on chemical safety databases, bringing whatever we learn into our production review. Transparency is critical. If a regulatory question arises, we are positioned to produce up-to-the-minute documentation and real production logs. This open policy reflects actual practice. Information moves in real time—whether it’s a new requirement for an export market or an unexpected customer audit, our team brings experience not just in production, but in compliance and communication.

    The Value Provided by Direct Manufacturing

    Being the primary producer grants more control and more responsibility. As a manufacturer, we don’t rely on intermediaries or imported drums from unknown partners. Every batch comes with a clear story, from raw input to final drum. Troubleshooting and upgrades—whether a tweak in dehydration, a shift in raw material pre-treatment, or a new packaging seal—stem from real-world discussions and feedback. Unlike products passed through brokers or re-baggers, our 2-Aminophenol-4-Sulfonmethylamide can be traced and tracked, which makes a palpable difference when users face a production hiccup or need tech support.

    Working directly with users across dye, pharma, and agro sectors, we catch issues invisible to casual traders—like the impact of microscopic crystals on blending, or the slow build-up of trace contaminants over repeated syntheses. Our operators understand more than just batch numbers. They track how process changes show up on the customer side. Technical teams are available not just for routine support, but to walk the line with engineers, test samples, and help adjust processes on-site, if needed. This hands-on connection is what we think marks a good chemical manufacturer.

    Addressing Challenges: Solutions from Shared Learning

    Challenges always arise, whether in the lab or warehouse. Mislabeled shipments, humidity spikes in storage, or changes in a partner’s process can all affect performance. By staying close to logistics partners, we’ve cut error rates in labeling and packaging. Our plant team works year-round to avoid bottlenecks, focusing on site safety and environmental controls—no discharge, better containment, fewer process upsets.

    Supply chain volatility now shapes markets more than ever. Holding reliable inventory levels, building in real-time batch tracking, and standardizing shipment protocols minimize the risk of stockouts or write-offs for our customers. We’ve learned to stay flexible, adjusting quantities, package sizes, and testing schedules to fit real demand. We know customers have been let down by over-promises elsewhere, so our team focuses on what’s deliverable and maintains open lines for discussing bumps in the road.

    Every issue leads to discovery and improvement. Sometimes, solutions are simple: swapping filter grades, installing backup sensors, or assigning more staff to visual inspection. Where problems reach up the supply chain, we’ve worked with raw material producers to screen contamination or adjust delivery schedules. Where technical specifications clash with real-world use, we partner with end-users to run tailored pilot batches before full-scale production.

    Forward Focus: Building Trust through Action

    The trust between chemical producer and end-user grows not only from quality but from responsiveness. Our experience with 2-Aminophenol-4-Sulfonmethylamide has repeatedly shown that open technical dialogue prevents most problems, and that transparency strengthens partnerships. We keep investing in plant upgrades based on user feedback, regularly review process controls, and stay up to date with changing safety and environmental needs.

    As chemical manufacturing evolves and requirements rise, we continue to integrate field experience back into every production run. Users find the peace of mind that comes from direct manufacturing: steady results, open communication, and the willingness to adapt. There is no substitute for knowing exactly how and why each batch meets the needs of those who depend on it downstream.