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2-Aminodiphenylamine

    • Product Name 2-Aminodiphenylamine
    • Alias N-Phenyl-o-phenylenediamine
    • Einecs 203-057-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    855504

    Cas Number 119-75-5
    Molecular Formula C12H12N2
    Molar Mass 184.24 g/mol
    Appearance Gray to brown solid
    Melting Point 97-99°C
    Boiling Point 350°C
    Density 1.15 g/cm3
    Solubility In Water Insoluble
    Synonyms 2-Aminodiphenylamine, o-Aminodiphenylamine
    Pubchem Cid 8332

    As an accredited 2-Aminodiphenylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 2-Aminodiphenylamine (100g) features a sealed, amber glass bottle with hazard labeling and a secure screw cap.
    Shipping 2-Aminodiphenylamine should be shipped in tightly sealed containers, protected from light and moisture. It must comply with regulations for hazardous chemicals, including proper labeling and documentation. The package should be cushioned to prevent breakage or leaks during transit and include appropriate hazard warnings per international and local shipping standards.
    Storage 2-Aminodiphenylamine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Protect it from light and moisture. Proper labeling and secondary containment are recommended to prevent leaks and accidental exposure. Personal protective equipment should be available when handling.
    Application of 2-Aminodiphenylamine

    Applications of 2-Aminodiphenylamine in Industrial Manufacturing

    2-Aminodiphenylamine supports several specialized downstream sectors as a key intermediate, especially where high-performance organic synthesis, antioxidant activity, or pigment composition is required. As the direct manufacturer, we ensure rigorous batch control and custom specification support for technical, regulatory, and end-use integration needs for each field.

    1. Rubber Antioxidant Production

    Rubber additive formulators use 2-aminodiphenylamine primarily as a precursor for high-grade antioxidants. During stabilization processes for both natural and synthetic rubber, the compound reacts with other intermediates in a condensation sequence, especially for non-staining antioxidant grades. Processing lines integrate this intermediate at the raw material agglomeration or masterbatch stage, ensuring precise control of dispersal in rubber matrices. The choice of dosage and purity directly impacts resistance against oxidative degradation during the service life of tire treads, conveyor belts, and industrial elastomer parts.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for additive manufacturing
    • GB/T 29517-2013 (China) Rubber chemicals—General specifications
    • REACH Regulation (EC) No 1907/2006 (Europe) for import/use registration
    • ASTM D4677—Standard Specification for Rubber Compounding Materials

    Typical usage ratio

    • In antioxidant synthesis, typically 1–5% based on polymer weight. Ratios adjust depending on final antioxidant concentration and target protection level for the rubber compound.

    Downstream process integration

    • Dosed as a primary or co-intermediate during condensation or rearrangement reactions to form antioxidant molecules before blending into rubber masterbatches.

    Final product types

    • Automotive and aviation tire compounds
    • Rubber industrial belts and hoses
    • Seals, gaskets, O-rings for machinery
    • Non-marking elastomer sports goods

    2. Synthesis of Azo and Polycyclic Dyes

    Colorant manufacturers employ 2-aminodiphenylamine as a coupling agent or chromophore builder in the preparation of complex azo or polycyclic aromatic dyes. It enters the diazotization/coupling reaction lines, which yield stable colorants for high-performance textile fibers, plastics, and ink systems. Purity control minimizes side reactions and batch color drift. Downstream, the performance of the dye relies on its molecular resistance, dispersibility, and lightfastness, achieved by precision in the initial coupling process.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (Textile safety)
    • EN 71-3:2019 (Toy safety—migration of colorants)
    • ISO 105-X12:2016 (Textiles—Tests for color fastness to rubbing)
    • EU Directive 2009/48/EC (Toy Safety Directive—azo dye restrictions)

    Typical usage ratio

    • As a coupling base, typically 0.5–3% w/w of dye batch, depending on the dyestuff’s target concentration and color depth.

    Downstream process integration

    • Introduced at the coupling stage after diazotization; reacts with diazonium salt under controlled pH and temperature for subsequent isolation, purification, and finishing of dye products.

    Final product types

    • Disperse dyes for polyester and acetate fibers
    • Azo pigments for PVC and HDPE plastics
    • Solvent dye formulations for inks and coatings
    • Colorants for textile yarns and technical fabrics

    3. Intermediate for Specialty Pharmaceutical Synthesis

    Pharmaceutical intermediate manufacturers use 2-aminodiphenylamine as a core building block in the synthesis of certain antihistamines, analgesics, and active pharmaceutical ingredients (APIs) that require biphenylamine skeletons. The raw material is introduced during the condensation, cyclization, or substitution steps within GMP-compliant multi-step synthesis. Stringent trace impurity control ensures process yields and consistent impurity profiles in the final API, critical for downstream regulatory submissions and quality assurance.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP–NF Monographs for related intermediates or APIs
    • 21 CFR Part 211 (US FDA Pharmaceutical CGMPs)
    • EU Guidelines for Good Manufacturing Practice (Part II—APIs)

    Typical usage ratio

    • Varies by pharmacopeial synthesis route; typically, 1–2 molar equivalents per reaction stage, adjusted based on product yield optimization and chemoselectivity of organic steps.

    Downstream process integration

    • Deployed in the early or mid-steps of API production, supporting ring closure, chlorination, or sulfonation reactions, followed by chromatographic purification.

    Final product types

    • Antihistamine agent precursors
    • Non-steroidal anti-inflammatory drug precursors
    • Pharmaceutical-grade colorant intermediates
    • Intermediates for neuroactive compounds

    4. Corrosion Inhibitor Formulation for Industrial Fluids

    The specialty lubricants and metalworking industry formulates corrosion inhibitors that leverage the chelating and antioxidant properties of 2-aminodiphenylamine. It is typically introduced into blending lines during concentrate preparation for engine oils, transmission fluids, or water-based coolants. The inhibitor functions by scavenging free radicals and passivating metal surfaces, prolonging machinery lifespan in power generation, automotive, and industrial environments. Manufacturers monitor formulation through in-process titration and residue stability testing.

    Industry compliance standards

    • ASTM D6557—Standard Test Method for Corrosion Control Additives in Petroleum Products
    • ISO 6743/6/2:2017 (Lubricants for metalworking—Industrial use)
    • SAE J1837—Corrosion protection for powertrain fluids (Automotive)
    • MIL-PRF-2104K (U.S. Military—Lubricating oil performance)

    Typical usage ratio

    • 0.1–1% w/w in concentrated fluid additive packages, with ratio depending on fluid type, desired protection level, and co-additives compatibility.

    Downstream process integration

    • Blended at the concentrate manufacturing step into oil base stocks or emulsions, then diluted or filled into finished lubricant or coolant packaging lines.

    Final product types

    • Engine and hydraulic oils for heavy machinery
    • Industrial water-soluble metalworking coolants
    • Automotive radiator and transmission fluids
    • Protective fluid concentrates for heat exchangers

    5. Precursor for Charge Transport Materials in Electronics

    The electronics chemical sector incorporates 2-aminodiphenylamine as a foundational molecule in synthesizing charge-transport agents for organic electronic devices. This compound is crucial in polymerization, ligand design, and redox shuttle systems in the manufacturing of OLEDs, organic photovoltaics, and photoconductors. Synthesis lines require high-purity, moisture-free input to guarantee electrical characteristics and minimize migration or yellowing in finished components. Real-time analytical monitoring checks batch conformity prior to device encapsulation or lamination.

    Industry compliance standards

    • IEC 62341-5-1:2011 (OLED—Display Requirements)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • JEITA Standard ED-8501 (Material requirements for organic semiconductors—Japan)
    • IPC-6012E (Qualification and Performance for Printed Boards—Circuit Boards)

    Typical usage ratio

    • 0.2–2.5% relative to polymer resin or charge-transport matrix, adjusted for application voltage and process yield.

    Downstream process integration

    • Fed into synthesis after catalyst introduction, then refined and incorporated into electronic material matrices during thin-film casting or vapor deposition.

    Final product types

    • Organic light-emitting diode (OLED) display materials
    • Organic photovoltaic panel coatings
    • Photoresists for microelectronic lithography
    • Conductore-active polymers for electronic inks
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    Certification & Compliance
    More Introduction

    2-Aminodiphenylamine: A Thoughtful Look at Our Product and Its Value

    What Sets Our 2-Aminodiphenylamine Apart

    Working hands-on in the field of chemical manufacturing means looking past what gets written in a catalog or posted on a typical website. In our production facility, 2-Aminodiphenylamine (CAS 133-08-4) doesn't just roll off an assembly line without careful attention paid to every stage of synthesis and quality control. Colleagues on the production floor know the smell, the color, the consistency — and how these details reward our customers over time. The chemical’s light brown to gray powder form signals to even a casual glance whether each batch shaped up to expectations. Small things, like how fine the powder flows, or how consistent the melting point stays from run to run, keep recurring for a reason: downstream users build their processes around reliability and small variations create much bigger problems later.

    From our vantage point, the applications that define this molecule are as important as its specifications. 2-Aminodiphenylamine, often discussed in relation to antioxidant systems and dye intermediates, demands steady hands in both its synthesis and handling. The product finds common ground in industries looking to extend the life of rubber — particularly in tire manufacturing, belting, and hoses. No one comes asking about the molecule for small jobs: companies want the process to work every time, and the chemistry to behave predictably every day of the year, no matter whether summer humidity or winter chill linger in their own plants. We understand this kind of expectation because we've seen what happens when minor inconsistencies catch up and disrupt a compounding line or undermine color retention in dyeing operations.

    Specifications and Consistency: What We Deliver

    A typical inquiry might focus on purity. Our standard production maintains a minimum assay of 98%. That number isn't simply a promise written on paper. Every batch undergoes multiple tests, before and after blending, using validated in-house and third-party methods. HPLC and GC analysis remain mainstays, but so do classical techniques that never lose their value in confirming residue profiles or by-product fingerprints. People ask why we bother with such diligence. We answer that experience with sensitive end-uses — such as stabilizing rubber against heat and oxygen attack — illustrates how a little extra focus reduces troubleshooting, saves on claims, and makes for stronger customer relationships. Many clients come to us after experiencing supply hiccups or mysterious failures stemming from inconsistency. That's when rigorous manufacturing — guided by operators who know what to look for — becomes a differentiator.

    Physical characteristics also influence where and how 2-Aminodiphenylamine gets used. The crystalline powder, subtle in hue and granular feel, fits smoothly into compounding lines, disperses in both polar and non-polar matrices, and stands up to temperature cycles typical in industrial processing. We see little value in coloring the truth about batch stability: moisture pickup can interfere with downstream applications, so we take pains to store, package, and ship in ways that minimize exposure. These efforts support clients needing reliable product from drum top to bottom, week after week.

    Applications: Understanding What Matters Most to Our Users

    Ask those with decades in rubber compounding about the role played by aromatic amines — and in particular, 2-Aminodiphenylamine — and the response isn't abstract. They’ve tracked field failures linked to ozone or heat cracking, examined color shifts in final products, and responded to warranty returns based on lost product performance. All of these problems circle back to the quality of preventive additives in the original formula. Our contribution starts with stable, high-purity intermediates.

    Our 2-Aminodiphenylamine heads most often into tire manufacturing, serving as an antioxidant and antiozonant. Not just major tire producers, but also makers of technical rubber goods, depend on its presence to slow cracking and embrittlement under high stress and ozone attack. Compared to other antioxidant options like p-phenylenediamines, customers note that 2-Aminodiphenylamine brings a profile better tailored to high-heat scenarios. Its aromatic structure, with two phenyl groups and an additional amine, does more than show up on a molecular diagram — it interacts at a practical level with rubber chemistry, resisting breakdown when other stabilizers flag.

    Outside the rubber sector, some clients rely on this compound as an intermediate in dye and pigment synthesis. The properties that complicate its handling — like its sensitivity to air and tendency for color change over time — are the same traits that make it useful in chemical transformations. In dye manufacturing, subtle purity differences or unwanted by-products in the starting material crop up later as off-shades in the finished batch. We continuously tweak and test our cleaning, blending, and storage steps to spare our partners these headaches. Our chemists and engineers notice the small things that keep downstream chemistry running on target.

    Comparisons and Key Differences: How Our Product Stands Out

    Over years of fieldwork, we've seen competitors take shortcuts: lower reaction temperatures to push out an extra batch, skip steps in filtration, fudge the final assay with a surface polish. Each shortcut invites trouble. Shortcuts lead to residual aniline, diarylamines, or darkened product that shows up later as visible defects or premature failure in high-value components. Our approach might not be the fastest, but it feeds long-standing partnerships. We would rather answer difficult technical questions and pursue better solutions, than explain late-stage failures or recall costs. Some manufacturers provide the chemical, but not the steady presence when downtime or complaints arise. We aim to avoid those situations from the beginning.

    Compared with related aromatic amines — say, N-phenyl-1-naphthylamine or phenothiazine — the advantages of our 2-Aminodiphenylamine show up in its blend of solubility, reactivity, and color stability. In certain dye and pigment recipes, it brings a cleaner endpoint and lets downstream chemists push for brighter color, tighter melting points, or simpler finished-product workup. In rubber, customers appreciate its balance between processability and protection: too much bulk-structure in some competitors’ products, too many low-melting by-products in others, not enough documentation or after-sales support to identify root causes when problems appear. By running every batch through both chemical tests and pilot application trials, we keep our solutions grounded in real-world production, not just lab theory.

    Upholding Quality and Transparency in Modern Manufacturing

    A reliable product grows out of more than just modern reactors and shiny lab instruments. In our experience, it comes down to a culture where operators, technicians, lab staff, and management each speak up and chase after incremental improvements. We've built these habits over decades — not months or years — and continue testing each change for practical impact.

    Clients often ask about regulatory documentation and compliance. Our teams keep current on developments in chemical policy — from REACH and TSCA to regional changes in labeling and pictograms. We maintain up-to-date safety and transport certifications, while ensuring underlying production stays ahead of tightening restrictions, especially with aromatic amines. Close tracking of impurity profiles and residual free amine is standard for us, not an afterthought. Our document sets show batch consistency, confirm raw material origins, and link every drum and bag to the reactor number and staff who oversaw the process. Full records and retention practices give our customers and their auditors what they're looking for during reviews and supplier qualifications.

    Manufacturing Insights: Lessons from Real-World Experience

    We recognize that reliability depends on more than just technical details. Over the years, we’ve seen raw material volatility, transportation hiccups, global disruptions, and shifting regulatory frameworks. Each event brings new lessons. Years ago, a delivery delay of o-nitrochlorobenzene from a key supplier forced us to rethink inventory practices. Cross-training with backup reactor lines, investing in additional purification equipment, and building long-term links with multiple logistics partners became the fallback. Some lessons only sink in when faced head-on: ramping up to triple shifts during surges in demand without compromising blend uniformity requires discipline and training.

    Our technical staff take pride in sampling — not just for routine quality checks, but for trend-spotting over time. We've tracked how minor feedstock variations, changes in ambient humidity during storage, or cold snaps within freight containers impact the finished product. Those learnings feed into tighter process controls and smarter specification limits. Involving our operators in continuous improvement meetings means on-the-ground awareness always informs big-picture planning.

    Addressing Challenges and Finding Sustainable Solutions

    Manufacturing aromatic amines, especially those based on diphenyl structures, doesn’t come without challenges. While waste management, emissions, and plant worker safety remain in the spotlight, our approach looks for solutions at every step. On the environmental front, solvent recovery systems, closed-loop filtration, and spent-acid neutralization setups reduce our impact and streamline compliance. We've switched several steps to aqueous and less hazardous solvents, investing in downstream cleaning to head off cross-contamination. Every improvement means less risk and a more robust final product.

    Workplace safety gets equal priority. Regular air monitoring, mandatory PPE, and routine medical screenings have become part of daily routines, not just compliance checkboxes. Discussions about possible skin sensitization, inhalation exposure, or accidental spillage move beyond paper policies. Everyone knows real stories about colleagues who caught a whiff of an off-odor, noticed a change in product color, or caught a pump seal issue during nightly checks. These past incidents set the tone for current vigilance and training.

    Seeking better performance doesn’t end in the reactor or QC lab. Feedback from high-use clients tells us which improvements hit home: upgraded packaging that weathers rough transport in humid climates, enhanced liners that cut down on product caking in long-term storage, or custom drum sizes for automated dosing. These details emerge from direct calls, site visits, and questions from line supervisors who use our material day in, day out. Our ability to adapt comes from staying tuned to operational realities, not just market analysis slides.

    Supporting the User: What Our Customers Tell Us

    The feedback from customers serves as both direction and discipline for us. No one wants surprises at the critical switch-over from one lot to the next on their production floor. A single off-spec drum out of hundreds shipped over the year erases months of goodwill. In one instance, a client manufacturing high-visibility colored hoses flagged an unexpected tint shift. Reviewing retained samples, running back the process records, and rechecking raw material origins uncovered a subtle spike in a by-product. The fix: review the stabilities of every additive and step in the process chain, building stronger limits into the next production run. This cycle of response and prevention doesn’t show up on an invoice, but it shapes loyalty and expectations on both sides.

    A few users have pushed us to continually refine packaging — keeping moisture and oxygen exposure near zero during storage and transit. These requirements led to heavyweight liners, redesigned closures, and traceable security seals. Transport partners have commented on our detailed forwarder instructions and labeling clarity. Avoiding any chance for cross-contact with food, cosmeceutical, or other sensitive goods means that traceability doesn’t end at the plant gate; it stays with a shipment until opened in the customer’s shop. Failures in the chain often expose where other suppliers get too comfortable — experience keeps us vigilant.

    The Road Forward: Commitment and Innovation in 2-Aminodiphenylamine Manufacturing

    Remaining competitive means more than just holding ourselves to industry benchmarks. Tomorrow’s challenges — ever-sharper emission standards, evolving attitudes around aromatic amines, shifting preferences for green chemistry — drive our development work. We’re experimenting with new catalytic steps, recycling secondary amines and refining plant-wide heat management schemes for more sustainable operations. Our technical team audits suppliers more frequently now, probing sustainability claims and tracking not just cost, but energy and water footprints.

    Having spent years immersed in the world of aromatic intermediates, we understand that lasting value emerges through attention to detail and the willingness to act. Shifting regulatory landscapes, global trends in material safety, and application-driven performance benchmarks keep us on our toes and push us to share new findings and offer prompt technical support. Navigating these changes, our commitment stands clear: maintain clear quality, consistency, and service for every customer relying on 2-Aminodiphenylamine to drive their own success.

    Informed Choices, Real-World Performance

    A lot of words could be spent on the theoretical attributes of 2-Aminodiphenylamine, but from our perspective as the manufacturer, its real value shows in the hands of those aiming to cut downtime, build better products, and stay ahead of evolving industry requirements. We’ve seen how strong relationships, built on trust, knowledge, and genuine curiosity, lead to advances everyone enjoys. Our daily drive to produce a product you can rely on, with answers rooted in experience, remains unchanged. We look forward to sharing our know-how, supporting new developments, and ensuring our 2-Aminodiphenylamine continues to mean something more than just a line on a balance sheet.