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HS Code |
258671 |
| Productname | 2-Aminobenzothiazole-6-Carboxylic Acid |
| Casnumber | 39229-51-7 |
| Molecularformula | C8H6N2O2S |
| Molecularweight | 194.21 g/mol |
| Appearance | Off-white to light yellow powder |
| Meltingpoint | 280-284°C |
| Solubility | Slightly soluble in water, soluble in DMSO |
| Purity | Typically ≥98% |
| Storagetemperature | 2-8°C |
| Synonyms | 6-Carboxy-2-aminobenzothiazole |
| Smiles | C1=CC2=C(C=C1C(=O)O)N=C(S2)N |
| Inchi | InChI=1S/C8H6N2O2S/c9-8-10-6-3-1-2-5(7(6)13-8)4(11)12/h1-3H,(H2,9,10)(H,11,12) |
As an accredited 2-Aminobenzothiazole-6-Carboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2-Aminobenzothiazole-6-Carboxylic Acid is supplied in a sealed, amber glass bottle with tamper-evident cap. |
| Shipping | 2-Aminobenzothiazole-6-Carboxylic Acid is shipped in tightly sealed containers to prevent moisture and contamination. The chemical is handled according to safety regulations, packaged in compliance with transport guidelines, and clearly labeled. Shipping usually occurs at ambient temperature unless otherwise specified, with required documentation for safe handling and regulatory compliance. |
| Storage | 2-Aminobenzothiazole-6-Carboxylic Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of heat or ignition. Protect the chemical from moisture, direct sunlight, and incompatible substances such as strong oxidizers. Proper labeling and secondary containment are recommended to prevent accidental spills and ensure safe handling. |
Applications of 2-Aminobenzothiazole-6-Carboxylic Acid in Industrial ManufacturingOur factory supplies high-purity 2-Aminobenzothiazole-6-Carboxylic Acid for targeted applications across key industrial chemical manufacturing sectors. Below is a focused review of real downstream uses in pharmaceutical synthesis, dyes & pigments, agrochemical intermediates, specialty polymer additives, and analytical reagent production. Each segment reflects actual customer processes and integration practices in global markets. 1. Pharmaceutical Intermediates for Anti-inflammatory Drug SynthesisChemical manufacturers utilize this raw material during multi-step synthesis of heterocyclic-based APIs, especially in the assembly of benzothiazole structured drugs indicated for anti-inflammatory activity. The carboxylic acid group provides a reactive handle for amide coupling or esterification, enabling rapid access to downstream active molecules. This intermediate integrates after initial aromatic substitution reactions, supporting strict analytical quality controls for residual solvents and unwanted isomers. Production environments carefully monitor batch records and cross-contamination to meet drug manufacturing expectations. Industry compliance standards
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2. Dye and Pigment Intermediates for Reactive Dye ManufacturingDye producers integrate this carboxylic acid derivative as a key intermediate during synthesis of reactive dyes, particularly those targeting fiber-reactive and metal-complex classes. The aminobenzothiazole moiety introduces chromophoric properties and enables subsequent sulfonation or halogenation. Operators charge the acid at the diazo coupling stage or amidation phase, ensuring controlled pH and agitation rates to maximize yield of colour-stable intermediates. Downstream manufacturers enforce batch colorimetry and lightfastness testing on the synthetic outputs. Industry compliance standards
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3. Agrochemical Synthesis: Herbicide IntermediateProducers of advanced agrochemicals use this material in the synthesis of select benzothiazole-based herbicides. The acid group participates in direct amidation with chlorinated agents or urea derivatives, forming intermediates that inhibit weed growth by disrupting enzymatic pathways. The product's quality and impurity profile directly affect downstream purity and selectivity. Formulation managers balance addition rates and reaction temperatures according to regulatory impurity limits for pyrazole or oxadiazole frameworks. Industry compliance standards
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4. Specialty Polymer and Resin ModifierPolymer compounders deploy this heterocyclic carboxylic acid as a modifier during synthesis of high-performance thermosetting resins and specialty engineering plastics. It serves as a functional chain-terminator or cross-linker, introducing targeted flexibility or solvent resistance in the final material. Process technicians monitor its controlled dosing alongside epoxy or phenol agents, tuning the copolymer architecture for property optimization. Batch integrity relies on in-process FTIR and GPC characterization to confirm successful incorporation. Industry compliance standards
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5. Analytical Reagent and Complexing Agent ManufactureLaboratory chemical producers select this compound as a precursor for preparing specialty analytical reagents and complexing agents used in trace metal analysis. Its structural features allow for further derivatization into ligands with selectivity towards transition metals, supporting volumetric titration or spectroscopic determination in regulated environments. Quality assurance officers adhere to strict protocols surrounding purity, water content, and trace metal background during batch manufacture, with custom blending on customer request. Industry compliance standards
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As a long-standing manufacturer with decades of synthesis experience under our belts, we see each molecule as a collaborated achievement between practical chemistry and real-world needs. 2-Aminobenzothiazole-6-Carboxylic Acid stands out as more than a catalog item— it's a trusted foundation for various research pipelines, pharmaceutical projects, and specialty chemical applications. In the hands of a producer who actually runs the reactors and plans the workflow, this molecule requires not only precision in its making but also a keen understanding of the practical expectations set by our industry and our clients.
As chemists, we respect the value of a compound with both aromatic stability and useful functional groups, such as the amino and carboxylic acid moieties. The position of these groups on the benzothiazole ring makes 2-Aminobenzothiazole-6-Carboxylic Acid a practical intermediate for those developing new pharmaceutical actives or advanced specialty materials. The molecule’s specific orientation guides predictable reactivity in subsequent steps—whether in amide coupling reactions or selective derivatization required for complex synthesis. Many clients bring us detailed reaction schemes showing where a slight impurity or a misplaced functional group would create failure down the line. Manufacturing this compound to a sharp specification is not alchemy; it’s grounded in manageable, monitored processes and years of problem-solving in scale-up and purification.
Producing 2-Aminobenzothiazole-6-Carboxylic Acid at any significant scale requires continuous improvements. Our teams have experimented with temperature controls, alternative solvents, and optimized filtering methods to drive higher purity and better recovery rates. These daily shop floor efforts translate to lot-to-lot consistency. Each kilogram delivers reproducibility in downstream chemistry, essential for teams working toward regulatory filing or academic publication. Story after story reaches our technical support desk: a research group wrestling with lot variance from other sources suddenly sees project turnaround after switching to our material—one batch matches the last, and the members finally get clear NMRs and efficient coupling. Lessons learned on our end? Lab-scale routines rarely translate directly; it takes guts to redesign a process line, and a willingness to invest in analytical methods that most resellers never see as necessary.
Our competitors offer benzothiazole derivatives with similar backbone structures but subtle differences in substitution pattern and purity profiles. Some suppliers push out 2-aminobenzothiazole or the simple carboxylic acid isomer, but overlook the rippling consequences that these variations hold for synthesis pathways. Cheaper alternatives often bring unexpected impurities or alternate polymorphs, which cause problems in reactions that aren’t intuitively obvious to non-manufacturers. From a process chemist's standpoint, the position of the amino and carboxylic groups—the “6” spot—profoundly affects electron distribution, reactivity, and solubility in polar solvents. Our customers have found that switching to our properly characterized product smooths out bottlenecks that arise with less precise isomers, saving both time and waste in pilot trials.
Clean chemistry does not happen by accident. Simple assay numbers or generic purity claims do not capture the complexity that goes into each batch of 2-Aminobenzothiazole-6-Carboxylic Acid. We don’t just lean on HPLC areas or single-point LCMS checks; we maintain robust screening by full NMR, elemental analysis, water content quantitation, and—when required—chiral purity checks. Technical teams painstakingly develop retention time standards, ensuring that the carboxylic acid group stands undisturbed and that no byproduct mimics the structure in downstream methods. Such detail matters when customers ship samples worldwide for third-party validation or build the molecule into a medical candidate requiring strict documentation. Before new batches leave our warehouse, specifications are not just met—they are dissected, each deviation chased to its root, and fixed, not forgotten. This approach stems from years of client-driven troubleshooting: if even a trace sulfoxide impurity pops up, our chemists overhaul the process instead of writing it off.
Shipping fine chemicals demands more than secure packing. A direct manufacturer like us handles regulatory compliance, cold-chain logistics if needed, and technical guidance tailored to customer protocols, all rooted in a clear understanding of the material’s chemical nature. 2-Aminobenzothiazole-6-Carboxylic Acid’s crystalline powder form can be sensitive to moisture and excessive light. From our experience, overlooked packaging details—such as inadequate desiccant or oxygen ingress—spell disaster down the line in sensitive synthesis contexts. Our logistics and warehouse crews work with sturdy, fit-for-purpose containers and define transit conditions up front, based on insights from actual reported issues and on-site audits. Fielding calls from a lab halfway across the planet with a question about hygroscopicity keeps us grounded in accountability, not marketing gloss.
Outside textbook summaries, the story of 2-Aminobenzothiazole-6-Carboxylic Acid lives in research stories—projects ranging from kinase inhibitor programs and agricultural protection chemistry, to dye intermediates and fluorescence probes. In pharmaceutical discovery, chemists often rely on this compound’s responsive amino group to cut reaction steps off multi-stage syntheses, which speeds up early-stage projects. Several pharma innovators push our material through amidation and Suzuki couplings, charting paths to new chemical entities. Commercial users value its stability and reactivity profile for scaling up initial laboratory hits to kilo production. As a manufacturer, our input does not end with the shipment; our technical staff takes calls about synthetic conditions, recommends purification tweaks, or offers custom modifications that tune reactivity or solubility further.
Manufacturing for scientists and engineers means working hand-in-hand, not just shipping whatever is in stock. On more than one occasion, end users have hit a wall in downstream processing—maybe solubility in a new solvent or crystallization issues for formulation R&D. Drawing on batch history and analytical archives, we can point them toward effective recrystallization solvents, or suggest modifications in the isolation steps that sidestep degradation routes. For custom bulk supply, we have adjusted particle size distribution, re-dried batches for improved shelf-life, and supplied detailed impurity profiles to regulatory teams. Unlike one-size-fits-all sellers, our practice is rooted in matching our output to real feedback from actual users, and making technical data transparent for review at each stage.
Responsible production means thinking beyond the compound’s final use. The benzothiazole framework in 2-Aminobenzothiazole-6-Carboxylic Acid is not one to take lightly when it comes to environmental fate or the safety impact of byproducts. Our environmental team studies process streams for legacy contaminants, flagging any trace that could raise compliance issues or public concern. Waste minimization programs start at process design, not afterthought—less solvent in, less effluent out. Over years, we have reduced the need for halogenated solvents and improved the ease of handling powders with safer, closed-system transfer, reducing inhalation risk for the workers directly handling this chemistry. A safety-first approach carries through to customer-level hazard communication, giving users honest hazard profiles based on actual manufacturer experience, not just Safety Data Sheet citations.
Delivering fine chemicals has taken on new urgency as global supply chains face bottlenecks from logistics shocks and raw material scarcity. We have weathered more than one supply crunch, thanks to a diversified sourcing approach and deep stockpiled inventories of critical intermediates. In one recent year, border slowdowns delayed imports for months across many sectors; our pre-investment in key precursor stocks allowed us to keep supplying pharmaceutical partners with virtually no interruption. Project managers on the client side appreciate candid delivery timelines, and our policy is to update not just on shipping status but on any emerging factors likely to impact batch release date. Our customers can plan, not guess, because hard data from the manufacturing floor reaches them early and in plain language.
In-house R&D teams depend on daily feedback to refine every manufacturing stage for 2-Aminobenzothiazole-6-Carboxylic Acid. From the start, pilot batches run side-by-side to commercial lots, each subjected to incremental adjustments. Sometimes those tweaks seem small—minor pH adjustments or alternative crystallization cycles—but over hundreds of cycles, these shifts build toward sharper purity and more efficient yields. The process of adopting feedback is not top-down but interactive; chemists from several continents have sent us pointers on hydration state effects and hints for downstream reactivity. We do not hide batch defects from internal review. Instead, learning from failed runs or flagged out-of-spec samples means our formulas evolve in lockstep with both user need and environmental compliance.
Our place in the value chain stretches beyond factory gates. Academic partners seeking gram quantities for fundamental mechanistic studies depend on our flexibility. Pharmaceutical and agrochemical developers need kilogram to multi-kilogram sums, delivered with both speed and a complete documentation trail. Multi-year supply agreements are supported by analytical transparency, not vague assurances. Our technical and sales teams act as one: chemists talking to chemists, drawing on lived examples, not boilerplate. Over the years, several startups and established R&D organizations credit much of their timeline acceleration to knowing their critical building blocks would not be the roadblock.
Markets shift, regulation tightens, and raw materials fluctuate. As a direct manufacturer, our edge comes from visibility over the entire lifecycle of 2-Aminobenzothiazole-6-Carboxylic Acid, from weighing the first charge to cleaning out the last reactor. Transparency in pricing and specification shields our customers from sudden surprises or veiled cost inflation. When global demand spikes unpredictably—from sudden discovery trends or regulatory shifts—we quickly realign capacity, communicating production schedules clearly. For those in research and production, knowing the story behind each batch, not just the headline spec, offers security in a competitive space where sloppy supply chain management costs real time and real money.
End users want reliable material and actionable insight from those closest to production. Our feedback loops are as open for a new Ph.D. student as they are to procurement heads negotiating multi-year contracts. Technical documentation goes beyond regulatory compliance, answering specific “how was it made?” and “has this process changed since last batch?” questions. Requests for alternate salt forms or higher-grade purification get serious review, not knee-jerk refusals. We review each proposal for custom synthesis closely, balancing plant safety, capacity, and use-case merit. Our priority remains centered on supplying 2-Aminobenzothiazole-6-Carboxylic Acid at quality and scale, drawing confidence from the thousands of batches already on record. Our practices reflect respect for the molecule, the chemistry, and the broader purpose it serves in the growing network of scientific progress.
Beyond selling a chemical, we join discussions in technical forums, international consortia, and scientific meetings, contributing knowledge gathered from both failed projects and successful launches involving 2-Aminobenzothiazole-6-Carboxylic Acid. We review published protocols, compare them with our in-house practices, and often offer analysis or troubleshooting in peer-to-peer settings. Our technical bulletins cover supply insights, regulatory updates, and sustainability practices, building a shared information ecosystem that benefits the broader user base. By staying current with literature, safety advisory trends, and raw material position papers, we stay ahead of both risk and opportunity. For clients who care deeply about steady quality, traceable manufacturing, and real technical support, our manufacturing footprint assures them that their material is more than a stock number.