Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Amino-P-Cresol

    • Product Name 2-Amino-P-Cresol
    • Alias 2-Amino-4-methylphenol
    • Einecs 220-487-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    755123

    Cas Number 95-84-1
    Molecular Formula C7H9NO
    Molecular Weight 123.15 g/mol
    Iupac Name 2-Amino-4-methylphenol
    Synonyms 2-Amino-p-cresol, 4-Methyl-2-aminophenol
    Appearance Light brown to reddish crystals or powder
    Melting Point 126-129 °C
    Boiling Point 310.6 °C at 760 mmHg
    Solubility In Water Slightly soluble
    Density 1.18 g/cm³
    Flash Point 162.5 °C
    Pubchem Cid 7352
    Smiles Cc1ccc(O)cc1N

    As an accredited 2-Amino-P-Cresol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Amino-P-Cresol is packaged in a sealed 100g amber glass bottle, labeled with chemical details, hazard information, and batch number.
    Shipping 2-Amino-P-Cresol is shipped in tightly sealed containers to prevent moisture and contamination. The chemical is classified as hazardous; therefore, it is transported in accordance with relevant regulations, such as DOT and IATA, with appropriate labeling and documentation. Protective packaging and temperature control may be required to ensure safety during transit.
    Storage 2-Amino-P-Cresol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and incompatible materials such as strong oxidizing agents. It should be kept away from direct sunlight and moisture. Follow all relevant safety protocols and ensure proper labeling to prevent accidental exposure or misuse.
    Application of 2-Amino-P-Cresol

    Applications of 2-Amino-P-Cresol in Industrial Manufacturing

    2-Amino-P-Cresol serves as a critical fine chemical intermediate in various industrial sectors. As the direct manufacturer, we supply this compound to strict industrial specifications, supporting rigorous downstream formulation, synthesis, and production standards. Below, we present core validated applications, each covering unique market pathways, compliance frameworks, usage ratios, process steps, and finished product integration.

    1. Hair Dye Intermediate for Oxidative Colorants

    Global cosmetic manufacturers use 2-Amino-P-Cresol as a primary precursor for high-purity, permanent oxidative hair dyes. In these applications, chemists blend this compound with selected couplers and developers, adjusting ratios for required shades ranging from browns to reds. Process operators integrate the material during the tint mass step, employing batch or continuous production, with strict in-process colorimetric monitoring. Quality control ensures residual levels after use finish below regulatory thresholds for consumer safety.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on Cosmetic Products (Annex III - Restricted substances)
    • US FDA 21 CFR 740 Subpart B - Hair Dye Regulations
    • Personal Care Product Council INCI Listing
    • IFRA Guidelines for Raw Material Traceability

    Typical usage ratio

    • 0.1–2.0% of total dye formula by weight, adjusted by required color depth and local maximum residue limits

    Downstream process integration

    • Added to pre-emulsified base at pigment grind or tint stage
    • Reacted with oxidizers (generally hydrogen peroxide) under controlled pH and temperature
    • Integrated in continuous or batch automatic mixing lines

    Final product types

    • Permanent oxidative hair dye creams
    • Professional salon tinting agents
    • Retail consumer boxed colorants

    2. Dye Intermediate for Textile and Leather Finishing

    Textile and leather processing plants employ 2-Amino-P-Cresol in the synthesis of azo and anthraquinone dyes. Technical staff use this intermediate to fine-tune dye tone, saturation, and substrate binding properties. Process engineers optimize addition points—either directly in the coupling reaction or post-sulfonation—dependent on fiber type and required end-use fastness. Batch-to-batch reproducibility remains critical, with occupational health controls over airborne and process-residual aminophenols.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical safety reporting
    • ZDHC (Zero Discharge of Hazardous Chemicals) Manufacturing Restricted Substances List (MRSL)
    • Oeko-Tex Standard 100 Annex 4 (aminophenol control)
    • GMP for Synthetic Colorants (ISO 9001, ISO 14001 for environment/quality)

    Typical usage ratio

    • 2.5–9% of dye stuff solid base; varies based on molecular design and desired color saturation

    Downstream process integration

    • Coupling reaction during azo dye synthesis batch
    • Post-chroming for leather finish dyes
    • Inline color adjustment in continuous dye lines

    Final product types

    • Reactive and direct dyestuffs for cotton and wool
    • Disperse dyes for polyester
    • Synthetic leather finish pigments

    3. Pharmaceutical Intermediate for API Synthesis

    API manufacturers integrate 2-Amino-P-Cresol in the staged synthesis of antipyretic, anti-inflammatory, and related active pharmaceutical ingredients. Chemists exploit the ortho-amino-cresol motif in ring closure, alkylation, or condensation processes—for example, when building antipyrine analogues or certain analgesics. Process validation targets traceability and impurity profiling through all critical steps, including QbD (Quality by Design) approaches adopted for regulatory dossiers.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) for APIs (ICH Q7)
    • European Pharmacopoeia Monographs relevant for downstream APIs
    • US FDA Drug Master File (DMF) referencing for intermediates
    • Japanese JP and Chinese ChP registration standards

    Typical usage ratio

    • Reactant ~0.3–1.7 molar equivalents per API intermediate; process chemist adjusts ratio for pathway yield

    Downstream process integration

    • Charged at initial step or during key condensation/cyclization stages
    • Monitored for trace/impurity carryover into the final API
    • Handled under validated cleaning and containment procedures

    Final product types

    • Antipyretic/analgesic active ingredients
    • Anti-inflammatory agents based on phenolic backbone
    • Synthetic antimalarial and anticonvulsant intermediates

    4. Stabilizer and Building Block for High-Performance Polymers

    Polymer R&D teams select 2-Amino-P-Cresol as a phenolic stabilizer and as a functional monomer for engineering resins. Its ortho-amino-phenolic structure serves dual roles: as an antioxidant during polycondensation and as a reactivity modifier in chain build-up for specialty coatings. Process engineers dose the compound in melt-blending or solution-polymerization stages, then rigorously validate integration with FTIR and thermal analysis tests.

    Industry compliance standards

    • ISO 9001 certified polymer QC and traceability
    • RoHS Restriction of Hazardous Substances (for electronics and coatings applications)
    • UL 94 (flame retardance where relevant)
    • REACH pre-registration for innovative materials

    Typical usage ratio

    • 0.5–3 phr (parts per hundred resin); higher loading used for stabilization, lower when acting as functional monomer

    Downstream process integration

    • Dosage at polymerization initiator stage (batch reactor or continuous line)
    • Solution dissolved pre-admixture or melt feed for copolymer
    • Ensured dispersion by high-shear mixing

    Final product types

    • Specialty phenolic resins
    • Epoxy and polyurethane coatings
    • High-temperature melt adhesives
    Free Quote

    Competitive 2-Amino-P-Cresol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Amino-P-Cresol: Genuine Insights from the Production Floor

    Introducing 2-Amino-P-Cresol (4-Amino-2-methylphenol, Model: 4APC-0035)

    For more than two decades, we have been manufacturing 2-Amino-P-Cresol at our chemical plant, watching shifts in market demand, industrial uses, and regulatory frameworks steer the landscape. In the daily operation of our facilities, quality is not just a promise—it is ground into every kilogram we ship. Clients often hear from traders and third-party sellers about 2-Amino-P-Cresol as just another intermediate or specialty chemical, but as the ones who actually synthesize it, handle the raw materials, and oversee each batch, we see its practical value differently.

    Molecule Profile and Key Chemical Properties

    Our team produces 2-Amino-P-Cresol (chemical formula C7H9NO), often referred to as 4-amino-2-methylphenol in the industry. The product’s typical appearance forms a pale brown crystalline or off-white solid under standard storage. Purity levels consistently reach above 98% by HPLC, with the remainder made up almost entirely of structurally related isomers and trace mineral content, never exceeding safe thresholds we monitor in-house. Moisture content remains well below 0.5%, with free phenol undetectable under our QA protocols. Melting point checks out between 117 and 121°C, and these tight physical ranges support downstream process reliability.

    Batch-to-batch consistency keeps our production floor running with minimal deviation, an important point not easily appreciated without hands-on manufacturing experience. We set our technical standards high, but meeting those numbers every day depends on more than paperwork—it comes from attention at every stage: raw cresol purification, precise ammonia handling, and structured heating-cooling cycles through our stainless reactors. Quality is easier talked about than actually delivered in drums and bags.

    Applications: From Hair Dyes to Advanced Polymers

    Most buyers inquiring about 2-Amino-P-Cresol focus on its role in hair dyes, where it serves as an oxidative intermediate, helping to build dark brown and black shades with better fade resistance than some older dye bases. There are performance differences in how color develops and holds, largely due to the specific arrangement of the methyl and amino groups opposite each other on the ring. That small change in structure shifts oxidative reactivity, which hair dye formulators rely on for controlling tone and stability.

    Beyond personal care, some clients in specialty polymer production and organic synthesis use 2-Amino-P-Cresol as a starting point for more complex molecules. For example, pharmaceutical manufacturers appreciate its dual functionality—having both an amine and a phenolic group—for driving condensation and coupling reactions. These features expand its reach beyond just colorants to include resin modifiers, antiozonants, and even corrosion inhibitors in customized lubricant packages.

    In our own factory, every ton leaving our doors was touched by real people—chemists tracking reaction endpoints and plant engineers watching pressure spikes in real time, not platforms or consultants. From polymer scientists tweaking molecular weights to dye houses adjusting hue, the raw material’s tight specification gives them less to troubleshoot downstream.

    Product Handling, Supply, and Storage Reality

    We never like to see theoretical shelf life cited without actual stories from the field. 2-Amino-P-Cresol, with its moderate volatility and reactivity, holds up well under proper storage—airtight drums, dry rooms, stable temperatures under 30°C. Yet, we have fielded calls from customers who took shortcuts, leading to partial discoloration, moisture uptake, or caking. Small physical changes can queue up process headaches, whether blending with dye precursors or charging into reactors.

    Shipping this material carries no high-hazard label under GHS, but that never excuses sloppy containment. Our approach uses triple-sealed fibre drums or HDPE lining, each batch uniquely tagged for traceability. We have heard more than a few tales from partners about repacked or mishandled material, which leads to extended cleaning cycles or odd color development. Experience says: reliable quality starts at the source, not in the warehouse.

    Where cost-sensitive clients may be tempted to try cheaper “substitutes” or off-grade alternatives with similar aromatic structures, our long-term users usually come back after one or two headaches. The tiniest deviation in the isomeric ratio can totally shift downstream reactivity—which means a misstep can kill a batch of expensive dye or pharmaceutical precursor. Engineers who have spent nights purging lines of contaminated resin know this all too well. We listen to their stories and use them as cues to push specification stricter year by year.

    What Sets 2-Amino-P-Cresol Apart from Lookalikes

    If you spend enough time in contract manufacturing, you see a steady stream of requests for alternatives: 2-amino-o-cresol, 4-amino-m-cresol, other aminophenol-methyl-derivatives. Chemistry textbooks can make these differences look trivial, but anyone who has run a full-scale synthesis line sees real-world contrasts.

    The specific position of the methyl and amino groups on the benzene ring does more than adjust a number on a report. This layout influences electron distribution, reactivity under oxidation, and even basic properties like solubility. Clients relying on 2-Amino-P-Cresol in dye synthesis see the difference in batch color—stability and shade shift dramatically compared to para-aminophenols or meta isomers.

    Resin modifiers also can’t swap in just any aminocresol without risking altered polymer branching or condensation rates. We have seen polymer chains crystallize differently based on subtle ring structure, impacting finished performance in coatings and cured adhesives. In our own test labs, switching out 2-Amino-P-Cresol for similar molecules gave consistently less predictable results—from cure time to product viscosity.

    It takes the right molecule for a job done right. Some market players try blending various aminocresols to cut raw costs, but downstream effects always emerge: discoloration, uneven cure, unpredictable shelf behavior. Honest conversations with quality control heads in both small and global firms have stitched together this lesson across the industry. Direct manufacturing experience with tonnage-scale operations backs it up: molecular detail cannot be skirted if the end goal is production that runs on time, every time, with no surprises.

    Sourcing Direct from the Manufacturer: Inside Accountability

    Our facility manages sourcing, synthesis, quality control, and direct distribution, minimizing the risk of mislabeling, contamination, or blending with lower-grade intermediates. Unlike brokers or warehouse retailers, our records track every batch from the storage tank down to individual drums and bags. Technical staff stand behind every lot shipped, and customers actually talk to our production chemists—not just sales reps—if a nuance in their process emerges.

    We have welcomed chemists from large multinational firms to walk our floor, review logbooks, and verify active filtration steps, ensuring what reaches their plants matches what lab-scale development promised. Anyone who runs a continuous or batch process knows the pain of a swapped intermediate. Avoiding those costly downtime events starts with clear lines of accountability and technical engagement.

    Our on-site R&D keeps tabs on process improvement too. We routinely adjust reactor conditions to minimize byproducts and fine-tune purification, based on what commercial users report as pain points. It’s not about building a sales pitch but preventing those moments when an entire dye lot turns a shade off, or a resin batch gels too soon. Hearing from users about their floor issues—then tracing those concerns back to actual process tweaks in our plant—keeps us grounded and drives continuous improvement.

    Quality Assurance: Life Beyond External Certifications

    Most chemicals move with paperwork in tow, covering ISO registrations, reach compliance, and safety certifications. While these badges show framework alignment, on-the-ground quality hinges on monitoring, constant feedback from end users, and accountability at every stage. For us, batch release only comes after an in-house panel of analytic tests. HPLC purity, melting point, moisture—these get checked every time.

    We sometimes find ourselves replacing third-party shipments that have failed a partner’s in-house QC—scenarios that reveal gaps in broader industry supply chain control. Our own QA never leans solely on documentation: process chemists inspect every lot before drums seal, with junior staff trained side-by-side on what a compliant batch actually smells and feels like. These skills take years to embed, and teach lessons no datasheet captures.

    Even as we keep pace with new regulations, true quality comes from the hands and eyes of those running the plant. Mistakes caught early keep engineers from having to clean day-long agitated reactors or toss whole shipments due to discoloration detected too late. People outside the industry sometimes see paperwork and think process control is a check-box exercise. In production reality, sustained quality means living and breathing every parameter, every day.

    Challenges in the Supply Chain, Lessons Learned

    Anyone working in specialty chemical supply over the last decade has seen abrupt price swings, feedstock shortages, and transport hiccups. For 2-Amino-P-Cresol, upstream costs—like high-grade cresol and ammonia—often jump at a moment’s notice after regional plant shutdowns or regulatory changes. Buyers dependent on short-term contracts find themselves scrambling for quality intermediates. Our choice has always been to maintain buffer stock of both raw materials and finished product, keeping customer lines running even during market squeeze.

    We have never relied on just-in-time ideals alone. Field experience tells us the gap between laboratory specification and industrial performance can swallow entire months of production if not managed with foresight. We have kept relationships with upstream suppliers tight, audited every year, ensuring traceable, sustainable access to starting materials. These are decisions shaped by production line emergencies, not spreadsheet idealism.

    Recent supply pinch-points have highlighted the difference between clients who chase price and those who bet on reliability. While bulk commodity buyers may risk blending or switching intermediates to save cost, specialty users repeat their orders based on trust in what they actually get—batch after batch. We hear from technical leads who remember surprises with generic intermediates: unexpected foam, color drifts, or poor conversion rates. Keeping ahead of such curve-balls only happens with manufacturing partners who know the entire story, not just the spot price.

    Responsible Manufacturing—Health, Safety, and Environmental Management

    Solvent extraction, pH-neutralization, filtration, and high-temperature reactions combine to create 2-Amino-P-Cresol, each carrying their own attention points. Our plant integrates regular environmental sampling, emission capture, and continuous operator training—not as paper exercises, but to keep everyone heading home safe at end of shift. In handling cresols and concentrated ammonia, reaction hazards are real for operators unless engineering controls keep air free of noxious vapors.

    Effluent handling receives more than rhetorical commitment. We run closed loop water recirculation, chemical scrubbers, and real-time monitoring of discharge, as required by both internal standards and local regulations. Overproduction leads to careful inventory control, not offshore dumping or off-grade sales, which too many in low-cost markets quietly rely on. For us, compliance is rooted in shared accountability; every person on our floor knows the consequences of a missed check, not from memos but because our team culture passes down field lessons year on year.

    Pricing Perspective: Direct Production Costs and Value Rationale

    Raw producer input always drives unit pricing. Sourcing high-purity cresol and managing ammonia oxidation steps with proper containment make up much of the real cost. Adding quality testing, responsible packaging, and warehousing turns a commodity chemical into a reliable tool for industrial users. We reject sub-grade lots at our own expense to ensure end users never face hidden costs mid-process.

    Some traders advertise discounted 2-Amino-P-Cresol sourced from brokers or overstock piles—product quality and handling history often remain a guess. In our experience, a few cents saved per kilogram at purchase can burn through tens of thousands in lost batches, cleaning, or reputation. For specialty users and technical managers, buying directly from those who actually make the molecule reduces risk and clarifies accountability.

    In lean times, we have absorbed price spikes on raw materials to keep partner deliveries whole. Trust runs both ways. Firms who build their pipeline around stable intermediates expect clarity on both lead times and technical support—not arms-length transactions from sellers lacking visibility on where a batch came from. Every plant outage, every disrupted campaign, becomes a case study for us, feeding back into our supply and cost policy.

    Why Experience Matters: Relationships Beyond the Transaction

    Long-term partnerships grow in chemical manufacturing not on price alone, but the lived experience of working through issues on the ground. We receive calls about process adjustments, dye discoloration mysteries, or scale-up headaches—conversations that lead to collaborative troubleshooting, process improvement, and sometimes the co-development of new material grades.

    Raw material supply is not immune to world events, technology shifts, or new environmental standards. Years in the field dealing with shutdowns, batch contamination, and shipping delays means we have built both redundancy and resilience into production and distribution. Technicians, QA engineers, and account managers at our plant know more about 2-Amino-P-Cresol than you’ll find in any datasheet. Every order carries that experience, and every returning customer validates it.

    Whether you need a steady drum supply for continuous coloring lines, or periodic orders for research-scale synthesis, partnering directly with manufacturers shapes the process far beyond the immediate transaction. Our commitment to material purity, specification control, and direct accountability remains constant—backed by stories and lessons built molecule by molecule, batch by batch, year after year.