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HS Code |
457506 |
| Chemical Name | 2-Amino-6-Chlorobenzonitrile |
| Cas Number | 29341-18-8 |
| Molecular Formula | C7H5ClN2 |
| Molecular Weight | 152.58 |
| Appearance | White to light yellow crystalline powder |
| Melting Point | 75-79°C |
| Boiling Point | 328°C |
| Solubility | Slightly soluble in water, soluble in organic solvents |
| Density | 1.27 g/cm3 |
| Purity | Typically ≥98% |
| Storage Conditions | Store in cool, dry place, tightly closed container |
| Synonyms | 6-Chloro-2-aminobenzonitrile |
| Smiles | C1=CC(=C(C(=C1)Cl)N)C#N |
| Inchi | InChI=1S/C7H5ClN2/c8-6-2-1-5(4-9)7(10)3-6/h1-3H,10H2 |
As an accredited 2-Amino-6-Chlorobenzonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2-Amino-6-Chlorobenzonitrile, 100g, is supplied in a sealed amber glass bottle with a tamper-evident cap and safety labeling. |
| Shipping | 2-Amino-6-Chlorobenzonitrile is shipped in sealed, chemical-resistant containers, protected from moisture and light. Packages are clearly labeled with hazard warnings according to international transport regulations. Shipments comply with all applicable safety guidelines, ensuring secure handling and accident prevention during transit. Proper documentation is included for regulatory and customs clearance. |
| Storage | 2-Amino-6-Chlorobenzonitrile should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizing agents and acids. Protect from moisture, heat, and direct sunlight. Ensure proper labeling and secure storage to prevent unauthorized access. Follow all relevant safety and handling guidelines for hazardous chemicals. |
Applications of 2-Amino-6-Chlorobenzonitrile in Industrial Manufacturing2-Amino-6-Chlorobenzonitrile acts as a critical intermediate in multiple industrial production chains. As an original chemical raw material manufacturer, we serve leading formulators and process integrators worldwide. We support precision applications in advanced APIs, specialty dyes, and agrochemical synthesis, adapting to each sector’s technical and compliance prerequisites. 1. Pharmaceutical Intermediates for Active Ingredient SynthesisThis compound primarily enters pharmaceutical manufacturing as an essential building block for certain active pharmaceutical ingredients (APIs), including anti-hypertensive and anti-cancer molecules. R&D and production processes rely on its stable reactivity for introducing aromatic amino and chloro groups, facilitating targeted functionalizations in multi-step organic syntheses. We supply large-scale reactors in validated GMP environments where this material ensures batch-to-batch reproducibility and meets strict impurity profiles. Industry compliance standards
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2. Agrochemical Synthesis (Insecticide and Herbicide Intermediates)Leading agrochemical manufacturers adopt this aromatic nitrile as a core intermediate in the synthesis of selective insecticidal and herbicidal agents. Its molecular structure allows controlled reactions for creating substituted benzamides and further functionalization into target active compounds. Good batch handling and analytical traceability underpin its use in regulated agrochemical production lines where field consistency and shelf stability are mandatory. Industry compliance standards
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3. Specialty Dyes and Pigments ManufacturingProducers of colorants utilize this material in specific dye classes where the aromatic amino and chloro groups increase substrate affinity and chromophore stability. The compound participates in key acylation and diazotization reactions during the synthesis of disperse, acid, and reactive dyes. Consistent purity levels and controlled moisture content ensure compatibility with downstream blending and finishing protocols in textile and polymer dyehouses. Industry compliance standards
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4. Fine Chemical Synthesis in Electronic Material PrecursorsSpecialty electronics manufacturers employ this compound as a precursor in the synthesis of aromatic intermediates for advanced materials, including liquid crystal compounds and semiconductor processing aids. The precise amino and chloro substituent positioning enables further derivatization, crucial for producing high-purity aromatic systems needed in optical and electronic applications. Purity specifications, trace metal control, and low residual solvents are essential throughout the process. Industry compliance standards
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5. Custom Intermediate for Chemical Research and Small-Molecule DevelopmentContract research organizations and specialty fine chemical houses rely on this aromatic nitrile for rapid synthesis of novel small molecules. Its dual functional groups accelerate route scouting for custom ligands, analytical markers, or innovative heterocyclic compounds. Our integrated supply chain supports laboratory-to-pilot translation, ensuring full trace documentation as required for patent filings and regulatory submissions. Industry compliance standards
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Over years of manufacturing specialty chemicals, we have seen certain products prove themselves again and again in demanding environments. One such compound is 2-Amino-6-Chlorobenzonitrile, a fine white to light beige crystalline powder. Our current model, manufactured at our facility under strict adherence to industry safety and purity guidelines, typically offers a purity above 99% by HPLC and a melting point falling in the range preferred by pharmaceutical and agrochemical customers. Packaging and sizing options adjust according to customer requirements, supporting both laboratory-scale and bulk industrial applications.
We understand how even small variations in input materials cause headaches on the production line. Purity, particle size, residual solvents—these aren't just minor specifications; they impact downstream synthesis, yields, and batch-to-batch consistency. Our focus lies in monitoring and controlling each step, from raw material sourcing to final product inspection, so every shipment delivers what the customer expects. Over the past decade, incoming feedback has confirmed that stable supply and proven lot repeatability let customers make formulation changes or scale-up with minimal worries.
This compound carries weight in industries where synthesis reliability matters. For pharmaceutical intermediates, 2-Amino-6-Chlorobenzonitrile’s molecular structure forms a versatile starting point for the creation of more complex molecules. Its combination of a reactive amino group and a nitrile handle, together with a strategically placed chlorine atom, supports a rich variety of transformations—nucleophilic substitutions, ring closures, amide formations, and Suzuki couplings, among others.
Pharma R&D teams turn to this material when laying out multi-step syntheses for active ingredients or fine chemicals. Reliable access to high-quality 2-Amino-6-Chlorobenzonitrile minimizes planning and re-qualification delays. Since our facility keeps demand-driven inventory, customers also avoid extended lead times or disruptions found with lower-volume or imported stocks.
2-Amino-6-Chlorobenzonitrile also finds use in agrochemical synthesis. In this sector, robust process chemistry supports the development of new active ingredients for crop protection. Chemical engineers choosing a nitrile with a well-positioned amino and chloro group get a head start on crafting scaffolds for herbicides, insecticides, or fungicides. Fine-tuning molecular features in the benzonitrile core often leads to new compounds with better efficacy or reduced environmental footprint. Customers appreciate knowing the precursor they specified will be readily available for pilot runs through full-scale commercialization.
The market today offers a range of substituted benzonitriles. Chemically, subtle differences in substitution pattern or functional groups can have major downstream impact. For example, 2-Amino-4-Chlorobenzonitrile and 2-Amino-6-Methylbenzonitrile each react differently under standard conditions. The chloro group at the 6-position in our product provides a unique reactivity profile—making certain nucleophilic aromatic substitution reactions more accessible while enabling selective derivatization elsewhere. Customers who tried switching to alternate materials report higher byproduct formation, changes in reaction yield, or even changes in regulatory compliance outcomes due to new impurities.
Our staff frequently consult with chemists choosing between isomers. Those responsible for greenfield process development can avoid costly re-validation steps by sticking to the tried-and-true 2-Amino-6-Chlorobenzonitrile core in their syntheses. Lessons learned from troubleshooting similar aromatic building blocks led us to invest even more in refining this product's analytical profile, ensuring lower residual solvents and cleaner chromatograms. The result: higher customer satisfaction and fewer project setbacks.
While specs might appear straightforward on a certificate of analysis, true quality depends on what happens on the shop floor. We adopted a closed-system approach to minimize contamination risks and ensure reproducibility. Batch records detail process controls for temperature, pressure, and mixing—slight tweaks in any of these variables influence purity and downstream safety data. Operators receive continuous training, reinforcing a culture where hands-on knowledge and pride in craftsmanship drive every batch.
We test each lot for purity, moisture, trace metals, and residual organics to ensure suitability for rigorous synthesis. Consistency means less rework at the customer’s plant and more time spent focusing on product innovation. We've learned over time that stability, both in the chemical sense and in supply chain reliability, matters just as much as any published assay data.
Responsible chemical production extends beyond quality checks. We prioritize environmental stewardship and workforce safety by investing in closed-system engineering, advanced air filtration, and automated waste handling. Our real commitment shows in maintaining full traceability on each raw material lot, working with inspectors to meet ever-tightening global environmental and safety regulations.
Downstream industries use 2-Amino-6-Chlorobenzonitrile for regulated applications. Our direct customers, whether in pharmaceuticals or crop sciences, want to know the upstream supply chain stands on solid ethical footing. Ongoing investments—in laboratory analytics, monitoring, and documentation—back our promises with proof, not just marketing. Auditors examining our facility have direct access to data confirming adherence to REACH, GHS, and other regulatory frameworks for safe handling and use.
Innovation in fine chemical manufacturing isn't limited to creating new molecules. Over the years, we've responded to industry requests for tighter purity brackets, customized particle sizing, or lower target levels for regulated impurities. Process adjustments took time. Our team worked through dozens of pilot trials to balance output yield with the added steps necessary for impurity reduction or crystallization control. What customers gained: a predictable product that matches specific synthesis needs, with clear documentation supporting every change.
Our technical service group maintains dialogs with synthesis chemists, offering insight drawn from large-scale production. Questions about solubility, compatibility with different solvents, or observed side-product formation get answers based on lab results and production experience. Customers taking on new product development projects value access to real, firsthand manufacturing insight. The technical team can supply bench-scale samples for process optimization long before larger orders get placed, reducing the risks associated with downstream scale-up.
Supplying a specialty molecule like 2-Amino-6-Chlorobenzonitrile requires more than simply reacting raw material and packaging the result. Our integrated facilities handle everything in-house, from raw material synthesis to purification and final packing. The advantage: tighter control over all input streams and a proven ability to address supply disruptions swiftly. During the recent raw material shortages faced globally, our facility’s flexibility and advanced inventory systems allowed us keep regular shipments steady without quality compromise or extended delivery times.
End users tell us this peace of mind gives their operations a significant edge, removing the uncertainty that sometimes comes from fragmented or brokered chemical supply chains. Our direct accountability for each production step means customers can trace each bag or drum back to a single origin, with documented oversight and traceability at every stage.
Our built-in quality assurance program covers more territory than routine wet chemistry or HPLC. Customers with sensitive downstream applications benefit from our investment in advanced impurity profiling using LC-MS, GC-MS, and elemental analysis systems. If a project demands, we review multi-year product consistency documentation and can provide detailed records on the observed impurity trends or batch performance for regulatory filings.
Some customers carry out demanding downstream scale-ups where even minor impurities interfere with complex transformations. Our analytical team works closely with theirs, exchanging data and feedback to ensure product fits the application and avoids unwanted side reactions. Years of direct lab and plant feedback have given us a proven workflow for fast troubleshooting and process modifications. Responsive support like this minimizes lost time and helps protect multi-million dollar R&D investments.
With tighter standards and growing scrutiny on chemical safety, the market for 2-Amino-6-Chlorobenzonitrile places a premium on traceability. Our company commits to not only maintaining compliance with international standards but also proactively seeking ways to improve transparency. From blockchain-supported batch logs for high-value shipments to digital certificates of analysis, customers gain confidence in both the materials themselves and the documentation supporting each delivery.
Feedback from downstream manufacturers shapes our priorities for process and documentation improvements. In cases where a regulatory authority raised concern over a particular impurity, our team worked backward through the synthesis and supply chain, pinpointing the source and adjusting process control points. This level of responsiveness isn’t possible without hands-on experience in chemical process engineering and a genuine partnership mentality with our customers.
Operating a chemical plant responsibly requires constant vigilance to manage effluent streams, minimize solvent waste, and deploy energy efficiently. For many years, teams across our facility have adopted new solvent recovery and closed-loop processes to cut the carbon footprint associated with producing 2-Amino-6-Chlorobenzonitrile. Filtration and post-reaction workup generate wastes, and managing these byproducts has shaped our approach to lean manufacturing.
We frequently share best practices from our own environmental audits with interested customers, who need hard data to back up sustainability claims in their own markets. Stepwise reductions in emissions, combined with ongoing investments in infrastructure modernization, have both improved our local environmental performance and also given our customers new confidence in the ethical footprint of their purchased materials.
Safe storage and handling routines for this compound stem from long operational practice, not just paperwork. Our packaging standards withstand tough transport conditions and maintain the stability required for extended warehouse storage. Customers dealing with regular batch inventory can rely on the stable shelf life under reasonable conditions, reducing the need for extra retesting or recertification repeated every few months.
During shipping, we use tamper-evident seals and robust containers, supported by real-world shipping route data to minimize temperature excursions, moisture ingress, or accidental exposure. All these steps evolved from incidents and lessons learned by the production team through hard experience on the factory floor. Because we manage logistics in-house, any issues reported by customers are checked against our own delivery logs, speeding up resolution.
R&D groups operating in pharmaceuticals, agrochemicals, or specialty polymers use 2-Amino-6-Chlorobenzonitrile to push the boundaries of molecular design. Its structural features allow rapid modification to test new hypotheses or improve bioactivity, and dependable upstream sourcing lets researchers focus on innovation, not procurement issues. Synthesis teams also run pilot batches to fine-tune yields, impurity profiles, or reaction efficiency before launching at full scale.
Our team supports development by providing studies and technical documentation that can smooth the path for regulatory acceptance or intellectual property protection. Whether crafting a new drug lead scaffold or building a smarter herbicide backbone, customers find value in a stable supply of this key aromatic amine, paired with guidance from experienced synthetic chemists who helped bring the substance to market.
Recent disruptions in global supply chains reinforced the value of domestic, vertically integrated specialty chemical manufacturing. Our proactive inventory management and deep supplier relationships buffer customers from delays seen elsewhere. Short-term supply interruptions not only hinder ongoing production but also risk regulatory compliance if substitutes bring unapproved impurities or variations. This is why we keep critical materials like 2-Amino-6-Chlorobenzonitrile in steady production, working well ahead of demand forecasts and keeping open communication with key customers.
We actively monitor input costs, freight routes, and market shifts, so that our customers have early warning if economic or regulatory changes threaten supply stability. When shortages hit the market, customers relying on imported intermediates can experience downtime or forced reformulation. With us, chemists reach out and often receive prompt updates directly from our operations team—no third-party red tape or confusion about lead times.
The fine chemical sector moves quickly, adapting to new science, regulations, and market needs. Standing still is not an option. Our long-term focus on dependable manufacturing, transparency, and active technical support grows out of the shared challenges faced by those who rely on 2-Amino-6-Chlorobenzonitrile. Industry partnerships, ongoing investment in process efficiency, and tight integration between plant and technical teams set the stage for continued improvement—both in the quality of molecules delivered and the trust built between supplier and customer.
With a history built on listening to end users and solving real-world challenges, we continue aiming for product excellence, regulatory transparency, and shared success. Sourcing the right intermediates drives progress in everything from pharmaceuticals to agriculture to materials science. The journey of a molecule, from plant to laboratory to final product, deserves careful attention. Through practical experience and hands-on commitment, we ensure that each shipment of 2-Amino-6-Chlorobenzonitrile helps support safer, more efficient, and more innovative chemistry worldwide.