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HS Code |
310041 |
| Iupac Name | 2-Amino-4-phenylbutane |
| Molecular Formula | C10H15N |
| Molar Mass | 149.23 g/mol |
| Appearance | Colorless to pale yellow liquid or solid |
| Cas Number | 22374-89-6 |
| Boiling Point | 232-233°C |
| Melting Point | 44-46°C |
| Density | 0.938 g/cm³ |
| Solubility In Water | Slightly soluble |
| Structure Type | Aliphatic amine with a phenyl group |
| Smiles | CC(CC1=CC=CC=C1)N |
| Inchi | InChI=1S/C10H15N/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6,9H,7-8,11H2,1H3 |
| Refractive Index | 1.519 |
As an accredited 2-Amino-4-Phenylbutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 100-gram amber glass bottle labeled "2-Amino-4-Phenylbutane," featuring hazard symbols, lot number, and tightly sealed screw cap. |
| Shipping | **Shipping Description:** 2-Amino-4-Phenylbutane should be shipped in tightly sealed containers, protected from light and moisture. It must be labeled as a chemical substance and handled according to applicable regulations for potentially hazardous materials. Transport in compliance with local, national, and international regulations, and ensure appropriate documentation accompanies each shipment. |
| Storage | **2-Amino-4-Phenylbutane** should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Protect it from moisture and direct sunlight. Proper labeling is essential, and access should be limited to trained personnel. Use appropriate chemical storage cabinets if available. |
Applications of 2-Amino-4-Phenylbutane in Industrial Manufacturing2-Amino-4-Phenylbutane plays a distinct role in a focused range of advanced manufacturing sectors, each governed by rigorous compliance protocols and specialized downstream processing requirements. As an original manufacturer, we support formulations and process integrations confirmed by real-world industry usage, keeping supply chain documentation and technical data fully aligned with B2B expectations and regulatory oversight. 1. Pharmaceutical Intermediate for CNS-Active Compound SynthesisIn the pharmaceutical sector, this material is routinely used as an intermediate in the multi-step synthesis of certain central nervous system (CNS)-active small molecules. Its benzylic amine functionality serves as a key building block for custom molecular scaffolds in late-stage process chemistry, where reaction control and impurity profiling determine batch reproducibility and regulatory acceptance. The precise loading must be matched to target molecule design, and production compliance verifications require full traceability from raw input to API output. Industry compliance standards
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2. Chiral Catalyst Component in Asymmetric HydrogenationChemical manufacturers utilize this material’s primary amine group as a precursor to chiral ligands for asymmetric hydrogenation, particularly when assembling fine chemicals or intermediates with enantioselective requirements. The fragment is first derivatized and anchored to a carrier, forming a ligand complex for transition metal catalysis. Loading varies by catalyst system, and documentation of chirality and conversion rates forms part of customer quality submissions. Industry compliance standards
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3. Intermediate in Advanced Polymer SynthesisPolymer manufacturers apply this amine-containing raw material as a chain modifier or end-capping agent in the synthesis of specialty polyamides and engineering thermoplastics. Its structural motif imparts improved flexibility and thermal performance by disrupting crystallinity. Formulators must monitor batchwise incorporation, and final resin performance is documented via in-house and third-party compliance testing against application-specific benchmarks. Industry compliance standards
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4. Reagent for Analytical Derivatization in Laboratory DiagnosticsAnalytical chemistry laboratories use this raw material for derivatizing certain analytes in chromatographic methods. Its role as a derivatizing reagent stems from its amine functionality, which forms stable derivatives to improve detection, quantification, or separation in complex sample matrices. Preparation and use in this application are tightly standardized due to trace analysis requirements. Industry compliance standards
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After decades in the chemical industry, we have always placed a priority on quality, consistency, and process control. Every batch of 2-Amino-4-Phenylbutane we make traces back to strict sourcing standards and continuous improvement. Our production journey with this compound started in response to genuine industrial demand, especially from research teams developing intermediates and specialty chemicals. Reliable access to pure, consistent 2-Amino-4-Phenylbutane stands or falls with how the manufacturer approaches synthesis, purification, and logistics. Our factory lines developed alongside these specific needs rather than adapting a stock product for a range of uses.
2-Amino-4-Phenylbutane, also known in scientific circles as α-phenylbutylamine, calls for rigorous manufacturing standards. Our clients and development chemists expect clarity about molecular structure, purity, and handling requirements. Every lot of our material runs through analytical methods including NMR, HPLC, and GC-MS. Each of these techniques gives a different window into molecular identity and the absence of isomers or extraneous impurities.
What sets this compound apart comes through practical observation. The solid powder form offers ease in handling and precise measurement, especially compared to oily analogues prone to air or moisture uptake. Routine inspections during drying and packaging catch any deviations before the material leaves our facility. We monitor melting point, particle distribution, and color closely. By controlling reaction temperature and time during synthesis, our process consistently holds purity to over 99%. This becomes particularly critical in chemical transformations with strict requirements on starting material quality. Any impurity can ripple through subsequent steps, so we address it at the very beginning.
Process engineers, QC staff, and production supervisors all understand how seemingly minor imperfections can escalate. We've responded to these realities by configuring our batch reactors for efficient agitation and uniform heating, ensuring conversion rates avoid the formation of unwanted structural isomers. Our teams use in-line monitoring, which cuts down on batch-to-batch fluctuation. Observations from the shop floor feed directly into improving synthesis cycles and preventing contamination.
We have found that storing and transporting 2-Amino-4-Phenylbutane benefits from an airtight package – an approach learned first-hand after noting that open drums exposed to humid conditions sometimes led to slight agglomeration or yellowing. These lessons taught us to adopt double-sealed bags and invest in climate-controlled storage, reducing such risks to negligible levels. Only direct observation over years of shipment deliveries and warehouse cycles brought this to the fore.
In our discussions with chemists working in pharmaceutical intermediates and specialty monomers, the importance of 2-Amino-4-Phenylbutane grows from its role as a robust building block. Research teams prefer our solid, high-purity material for reductive amination, N-alkylation, and catalytic transformations. The primary amine group ensures targeted reactivity, and the phenyl ring provides access to compounds with increased lipophilicity or aromatic functionality. Having a dependable source cuts unexpected delays from material variation, and our history with custom projects means we can address unusual synthesis needs.
Purchasers from specialty polymer plants look for higher assurance on thermal stability and minimal off-gassing. During early collaboration, one plastics customer showed us how trace impurities from other vendors’ batches produced off-smells during extrusion. Once they switched to our powder, that issue subsided, since our in-process controls kept contamination in check. Our consistent feedback loop between factory, application testing, and customer teams helped zero in on finer points like granularity and carrier solvent compatibility.
Comparing 2-Amino-4-Phenylbutane to structurally similar amines reveals genuine distinctions. We often get inquiries from researchers debating whether to use this molecule or a branched-chain analogue. The straight-chain backbone and the position of the aromatic ring in 2-Amino-4-Phenylbutane shape both reactivity and downstream performance. Branching at the butyl group, for instance, changes the boiling point and can complicate crystal formation. Odd odors and compromised color stability can result from these minor changes at the molecular level.
Another comparison comes up with phenethylamine derivatives. That class offers higher volatility and different amine reactivity. 2-Amino-4-Phenylbutane shows distinct solubility in organic versus aqueous systems. Our lab testing backs this: recovery from neutralization steps, extraction into toluene or ethers, and precipitation for isolation run smoother with this compound than more hydrophilic alternatives. Over the years, our formulation branches tracked and logged hundreds of trial outcomes with these candidates—a data set that guides our process tweaks and recommendations.
We avoid selling near analogues as direct replacements since the results in the end product rarely align. Synthetic teams in fine chemical development benefit from clear separation between similar amine choices, and our experience helps steer users away from false economies.
Factory work on 2-Amino-4-Phenylbutane starts long before the first beaker. Raw material sourcing, in real-world settings, plays as large a role as the technical sequence of reactions. Over time, we discovered that minute impurities in starting phenylbutanone created subtle color shifts or compromised shelf stability. We contract with upstream suppliers willing to tailor-grade inputs rather than rely on commodity offerings. Random spot checks in the receiving warehouse added an extra line of defense.
The operator eye remains the ultimate check, even in a data-dependent plant. Our senior technicians spot slight irregularities in texture or hue that instruments alone might miss, acting as an early warning for investigation. Manufacturing at significant scale taught us to accept no shortcuts at the expense of reliability. Cycling equipment for cleaning and batch turnover does not come at the cost of cross-contamination—each client batch receives separate verification. While automation boosts efficiency, we keep people intimately involved at every stage for assurance.
Any material leaving our site includes a set of certificates drawn from genuine analytical data, not simply industry conventions. Each year, we run stability studies across different environmental conditions to confirm shelf life. Our documentation archive includes data on melting point, moisture level, particle size distribution, and heavy metal content. These records track original readings rather than rounding to meet expectations.
One trend that emerged over time: laboratory-prepared 2-Amino-4-Phenylbutane seldom matches the consistency of the continuous manufacturer. Scaling batch volumes improves reproducibility and controls minor side reactions often invisible on the bench. Having an internal analytics team builds the capacity for troubleshooting and developing custom methods when standard protocols fall short. Inspection of long-term retained samples confirms batch repeatability.
Handling chemicals, regardless of hazard class, requires diligence rooted in culture more than just regulations. For 2-Amino-4-Phenylbutane, routine staff training focuses on safe transfer, precise weighing, and rapid identification of packaging damage. Our procedures reflect the lessons learned over years of system upgrades and responses to inspection findings. Fielding occasional client questions about safe incorporation into closed systems—especially with automated feeders—has made us refine the overall chain of custody.
A partnership mind-set with our customers resulted in joint process safety reviews too. One example: some users asked about vapor pressure when increasing process temperatures. In response, our team set up pilot trials and provided vapor containment strategies that later entered wider operational practice.
Waste minimization efforts started decades ago, long before legislation shifted. In our plant lines, unreacted starting materials and side products from 2-Amino-4-Phenylbutane syntheses get segregated for solvent recovery or downstream conversion rather than bulk disposal. Environmental audits flagged process water contamination thresholds, so we put in place closed-loop rinse cycles and online conductivity monitoring. These steps not only reduce environmental impact but cut unforeseen costs.
Clients sometimes come to us with post-application waste reduction goals as well. Our technical support group has spent time in customer plants, examining how to optimize transfers and minimize container residue. Over the years, collaboration across manufacturer and end user sites has gradually driven down overall loss.
We owe many process refinements to direct client feedback. One pharmaceutical customer noted that their crystallization step became unpredictable with past suppliers. After in-depth walkthroughs and shared analytics, we traced the problem to minor secondary amine contaminants. By adapting purification steps and verifying with extended-run chromatography, batch-to-batch consistency returned. Open channels like this, backed by decades of continuity between our production and support teams, foster sustainable relationships.
Genuine manufacturer-customer collaboration allows advanced warning of downstream changes. Whenever formulation scientists introduce new chemistries or regulatory targets shift, we adapt our product and protocols by drawing on current production records, recent delivery case studies, and QC archives. No off-the-shelf datasheet stands in for the lessons logged by our people, who maintain a detailed timeline of process, inquiry, and solution.
Every shipment of 2-Amino-4-Phenylbutane we send can be traced through our records—from origin, batch operator logs, raw material COAs, stepwise analytical data, and shipment tracking. Decades in chemical manufacturing underscore that full traceability prevents costly confusion, supports fast troubleshooting, and anchors customer trust. Whether a client calls with a question five months after receiving material, or three years later referencing archived lots, we can backtrack every detail.
Early in our manufacturing life, mislabeling or incomplete records caused major headaches for both us and outside partners. Rigorous paper trails and digital archiving arose not only from compliance requirements but real-world mishaps. Our trust in thorough documentation pays dividends with each successful delivery and problem-free customer audit.
Shifts in raw material costs, demand cycles from pharmaceutical partners, and evolving research needs continually drive our process improvement. Fluctuations in global supply chains caused us, more than once, to revisit and secure alternative feedstocks for 2-Amino-4-Phenylbutane without sacrificing purity or timeline. Our in-house R&D group leverages trends in downstream science, anticipating what tomorrow’s novel drugs, polymers, or analytical targets might require.
Over the years, this forward-looking approach let us stay ahead of sudden spikes in usage, pandemic-induced delays, and regional policy changes. Investing in flexible lines, staff cross-training, and local warehousing provides a buffer against shocks. The result is less downtime and faster turnaround for shipments, drawing repeat orders from clients that need certainty.
Experience shows that no two ounces of 2-Amino-4-Phenylbutane are exactly alike without rigorous QA practices. Paying attention to minor process improvements—such as updating agitation speeds in reactors, validating every piece of glassware, or trialing enhanced filtration media—reaps cumulative gains in product stability and application reliability. Even seemingly minor batch inconsistencies can disrupt sensitive syntheses or delay development programs.
We encourage our partners to share not just specifications but the particulars of their process environment, so we can tailor recommendations or suggest process tweaks. Factory visits and technical exchanges supply insights impossible to gain from paper alone.
As new research applications for 2-Amino-4-Phenylbutane continue to emerge, our experience as a direct manufacturer keeps us alert. We respond to evolving standards in pharmaceuticals, advanced materials, and specialty syntheses not by relying solely on established methods, but by real-world problem-solving at every stage. Tightening requirements on impurity profiles and traceability raise the bar—challenges willingly met through staff training, facility upgrades, and transparent process records.
Our reputation for consistency rests on the vigilance of every operator, supervisor, and chemist who handled this compound across its production history. Only direct, long-term manufacturing experience captures both the triumphs and the rare missteps necessary to deliver 2-Amino-4-Phenylbutane as a dependable, high-purity building block. For every request that lands on our factory floor, we listen, adapt, and get better, batch by batch.