Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Amino-3,5-Dimethylbenzoic Acid

    • Product Name 2-Amino-3,5-Dimethylbenzoic Acid
    • Alias 2-Amino-m-xylene-5-carboxylic acid
    • Einecs 216-473-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    890292

    Product Name 2-Amino-3,5-Dimethylbenzoic Acid
    Cas Number 13316-12-4
    Molecular Formula C9H11NO2
    Molecular Weight 165.19
    Appearance Off-white to yellow solid
    Melting Point 159-163°C
    Purity Typically ≥98%
    Solubility Slightly soluble in water; soluble in organic solvents
    Synonyms 2-Amino-m-xylene-5-carboxylic acid
    Smiles CC1=CC(=C(C=C1N)C(=O)O)C
    Inchi InChI=1S/C9H11NO2/c1-5-3-6(2)9(10)7(4-5)8(11)12/h3-4H,10H2,1-2H3,(H,11,12)
    Storage Conditions Store at room temperature in a dry place
    Ec Number 236-362-0

    As an accredited 2-Amino-3,5-Dimethylbenzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, labeled "2-Amino-3,5-Dimethylbenzoic Acid, 25g," with hazard symbols, tightly sealed cap, and desiccant pack inside.
    Shipping 2-Amino-3,5-Dimethylbenzoic Acid is typically shipped in tightly sealed containers to protect against moisture and contamination. It should be handled as a chemical substance, following standard safety protocols. Shipping is done in compliance with local, national, and international regulations, ensuring safe transport and proper labeling for laboratory or industrial use.
    Storage 2-Amino-3,5-Dimethylbenzoic Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizing agents. Protect it from moisture, direct sunlight, and sources of ignition. Proper chemical labeling and secure shelving are recommended to prevent accidental spillage or exposure. Always follow relevant safety protocols and local regulations.
    Application of 2-Amino-3,5-Dimethylbenzoic Acid

    Applications of 2-Amino-3,5-Dimethylbenzoic Acid in Industrial Manufacturing

    2-Amino-3,5-Dimethylbenzoic Acid plays a crucial role across multiple specialized chemical manufacturing sectors. We supply high-purity grades directly to downstream processors who use this intermediate for targeted synthesis of dyes, pharmaceuticals, specialty pigments, and advanced polymer additives. Below we outline key industrial applications, usage ratios, compliance standards, integration in production, and typical finished products.

    1. Synthesis of Pharmaceutical Intermediates for Antibacterial Agents

    Pharmaceutical manufacturers incorporate 2-Amino-3,5-Dimethylbenzoic Acid as a building block to synthesize advanced antibacterial compounds, particularly benzoic acid derivatives for oral and topical dosage forms. The material undergoes amidation, chlorination, or condensation to yield target molecules, and producers rely on precise input ratios for reproducible purity and quality in subsequent stages.

    Industry compliance standards

    • Good Manufacturing Practice (GMP, ICH Q7)
    • USP/NF monograph requirements for intermediates
    • EU EudraLex - Volume 4 standards
    • FDA 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • 0.8 – 1.2 mol equivalents based on target active pharmaceutical ingredient synthesis scale; adjusted for reaction pathway and yield

    Downstream process integration

    • Material charged in initial synthesis step for acylation or coupling reactions under controlled dry conditions
    • In-line sampling enables in-process testing for purity and conversion before downstream isolation

    Final product types

    • Quinolone antibacterials (e.g., ciprofloxacin precursors)
    • Sulfonamide-based antibiotic intermediates
    • Active ingredient synthons for branded generics

    2. Manufacture of Specialty Azo Dye Intermediates

    Dye producers use 2-Amino-3,5-Dimethylbenzoic Acid as a diazo component to develop high-performance azo dyes for textile, leather, and ink applications. The acid group and ortho-dimethyl substitution ensure color fastness and unique chromatic properties during coupling with stabilizing agents. The material supports consistent batch-to-batch shade control.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006
    • OEKO-TEX® Standard 100 for textiles
    • ZDH/Industriegewässerverordnung (German wastewater ordinance for dyestuffs)
    • Quality management per ISO 9001:2015

    Typical usage ratio

    • 0.95 – 1.05 mol equivalents vs coupling component depending on dye structure and final application

    Downstream process integration

    • Introduced after precise pH adjustment for diazotization phase, followed by staged coupling with aromatic amines
    • Filtration and purification steps designed to minimize isomer impurities

    Final product types

    • Reactive dyes for cotton and viscose
    • Acid dyes for wool and silk substrates
    • Direct dyes for cellulose fibers
    • Inkjet printing colorants for digital textile printing

    3. Preparation of Organic Pigment Precursors

    Pigment manufacturers use 2-Amino-3,5-Dimethylbenzoic Acid as a key aromatic acid in the synthesis of complex organic pigments. The material supports thermal and chemical stability enhancement in final pigments, which are essential for plastic, coating, and automotive finish industries seeking long-lived, bright coloration.

    Industry compliance standards

    • EN 71-3:2019 Safety of toys – Migration of certain elements
    • ASTM D5538 for organic pigment purity
    • ISO 14001:2015 for environmental management during pigment production
    • Canada DSL/NDSL inventory regulations

    Typical usage ratio

    • 20–35% by charge mass relative to total aromatic compounds; optimized per pigment structure and color depth

    Downstream process integration

    • Charged into condensation reactors before final precipitation and grinding
    • Integrated in pigment synthesis upstream of solvent degassing and milling phases

    Final product types

    • High-stability red and orange pigments for plastics
    • Coating pigments for automotive paint systems
    • Masterbatch color concentrate granules
    • Solvent-based printing ink pigments

    4. Modifier in Polyamide and Polyester Polymerization

    Specialty polymer producers utilize 2-Amino-3,5-Dimethylbenzoic Acid as a functional chain stopper and comonomer in advanced polyamide and polyester processes. Adding controlled quantities enables manufacturers to tailor polymer crystallinity, dye receptivity, and mechanical performance according to application-specific requirements in engineering plastics and technical fibers.

    Industry compliance standards

    • ISO 9001:2015 (quality systems for polymer production)
    • EU Regulation (EU) 10/2011 for plastics intended for food contact (if applicable)
    • FDA 21 CFR 177.1500 for nylon resins used in repeat-use articles
    • REACH Substance of Very High Concern (SVHC) requirements

    Typical usage ratio

    • 0.3–0.8% w/w based on total monomer charge; response-adjusted for viscosity and terminal group balance

    Downstream process integration

    • Metered addition at polymerization feed stage
    • Monitored by online viscosity and color control for batch or continuous polymerization setups

    Final product types

    • Modified polyamide (Nylon) pellets for industrial injection molding
    • Dye-receptive polyester fiber for automotive upholstery
    • High-clarity engineering thermoplastics for electronics

    5. Intermediate for Agricultural Chemical Active Ingredient Synthesis

    Agrochemical synthesis companies rely on 2-Amino-3,5-Dimethylbenzoic Acid for producing high-value intermediates in herbicide and pesticide active manufacturing. The unique substitution pattern enables selective functionalization and compatibility with various reaction partners during process scale-up for commercial agrochemical APIs.

    Industry compliance standards

    • FAO/WHO Technical guideline for pesticide specification
    • GLP (OECD Principles of Good Laboratory Practice)
    • China GB 2763 Pesticide Residue Maximum Limits (if exported to China market)
    • ISO 17025 for analytical laboratory competence during QC

    Typical usage ratio

    • Varies from 0.6–1.1 molar equivalents dependent on the synthetic pathway, adjusted to optimize conversion and minimize residual byproducts

    Downstream process integration

    • Initial condensation or cyclization step for complex aromatic ring structures
    • Quality control through HPLC assessment pre- and post-reaction

    Final product types

    • Active intermediates for post-emerge herbicides
    • Synthetic intermediates for fungicides
    • Precursors for selective insecticide actives
    Free Quote

    Competitive 2-Amino-3,5-Dimethylbenzoic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Amino-3,5-Dimethylbenzoic Acid: The Manufacturer’s Perspective

    Honest Work, Consistent Results

    Every batch of 2-Amino-3,5-Dimethylbenzoic Acid that leaves our plant tells a story of focused attention and chemical precision. Over the years, we have seen the needs from chemists, pharmaceutical developers, and specialty product manufacturers grow more sophisticated. Meeting those needs takes clean raw materials, well-calibrated equipment, and a team that understands why each step—from synthesis to purification—shapes the final outcome. As direct producers, we witness firsthand the small adjustments that make the biggest differences in purity and reliability, helping our customers trust every shipment they receive.

    Model and Specifications Built on Experience

    The technical name for this molecule communicates the essential: a benzene ring, amino group at position two, and methyl groups at positions three and five, along with a carboxylic acid. Over many runs, we’ve fine-tuned our process to produce this acid to high levels of purity. Standard batches come out as an off-white to pale yellow solid, ready for further synthesis after mild drying. Typical melting point falls around 185-189°C, which matches consistent yields and helps confirm the absence of main impurities. From experience, we know even slight deviations in color or melting range point to side products—so we monitor each batch for any drift outside the well-proven range.

    Moisture content always receives extra attention. Even a bit of extra humidity can impact how this compound reacts downstream. Every batch comes out after oven drying, and we run Karl Fischer titration to confirm water sits below recognized thresholds. By handling these checks in-house, we have shielded customers from hair-pulling delays caused by sticky or inconsistent solids. Each drum, each bag—the same careful checks, with clear documentation that has stood up to detailed audits from major industry partners.

    Why Purity Matters in New Synthesis

    We see 2-Amino-3,5-Dimethylbenzoic Acid heading to a wide range of applications, yet the one thing customers ask about most is purity. Unlike traders, who may not see the end results, we hear directly from researchers when a sulfonamide synthesis stalls or a specialty pigment comes out off-shade. Minor contaminants—byproducts of an unoptimized reaction or incomplete workup—cause complex downstream headaches. Pharmaceutical partners especially tend to set tight purity specifications for every incoming lot. Meeting these isn’t just a checkbox for us; it stems from running thousands of kilogram-scale reactions and knowing that cuts and shortcuts lead to more re-crystallizations and impatient clients. A typical specification we ship regularly features 98% minimum purity as determined by HPLC or GC, but for more critical pharma applications, we have developed processes that push well above 99.5% on customer demand.

    Beyond the main peak, trace amounts of xylene derivatives and unreacted starting material can create real havoc. Unlike the broader market, we avoid shortcuts in workup, opting for multi-stage crystallization. Our staff inspects solids for foreign color or odor, and if anything looks suspect, we halt packaging and run deeper analytics. Years of hearing feedback from chemists—sometimes unsolicited—have convinced us that robust purity brings more repeat orders than an attractive sales sheet.

    Consistent Particle Size for Higher Handling Quality

    Lab and factory handling depend on how a solid behaves during weighing, transfer, and charging. Over time, our customers taught us to standardize not only purity, but also physical form. By tuning our drying protocols and carefully controlling precipitation rates, we deliver a free-flowing powder that resists clumping. In our experience, a pourable consistency saves real time on busy production lines and guards against losses that cut into a department’s already tight margins. For anyone scaling up, a reproducible feedstock avoids the “lottery” of batch-to-batch surprises.

    Applications: Driven by Customer Needs

    Our record books tell a clear story: the majority of our 2-Amino-3,5-Dimethylbenzoic Acid sells to pharmaceutical research and development centers. Medicinal chemists use it as a building block for anti-inflammatory agents, specialty antibiotics, and enzyme inhibitors. Several clients synthesize benzothiazole derivatives or isoindoline compounds that only function well with reliable isomeric purity. We have also seen customers use it as an intermediate for azo dye production, where precise control over functional group position ensures color consistency and light fastness.

    Organic electronics researchers reach out for this compound due to its conjugated aromatic core, which can be engineered into specialty conductive polymers. Agrochemical developers, too, use our acid for coupling reactions leading to novel herbicides and fungicides. In each field, small differences in impurity profile translate to weeks lost on process troubleshooting, which only manufacturers see up close. We work directly with teams refining their synthetic routes, offering technical feedback on solubility, stability, and reactivity issues. Our doors stay open to clients who need more than a stock catalog solution; most times, they want honest advice on how to scale with fewer surprises.

    Standing Apart From Generic Options

    Walking through industry expositions, we hear the same questions about “how our product differs.” Some resellers offer generic 2-Amino-3,5-Dimethylbenzoic Acid, often sourced through layers of brokers. We’ve tested many of these samples at our own QC labs. They often suffer from inconsistent purity, broad melting point ranges, and variable particle size. In a few unfortunate cases, we’ve seen lots contaminated with unrelated aromatic amines or with residues from poorly washed glassware. These inconsistencies breed downstream costs, ranging from failed analytical runs to off-spec product recalls.

    By owning and controlling the entire chain—from raw material vetting to regular equipment recalibration—we hold ourselves to a traceability standard rarely matched in the market. Each batch receives a unique identifier tied back to recorded maintenance schedules, operator signatures, and detailed analytical logs. Customers who have battled unexplained process failures tell us the ability to trace each lot back to a single origin solves more problems than any price-based incentive. We have responded to requests for “old school” batch samples by maintaining retains from every production run for over five years.

    Instead of viewing 2-Amino-3,5-Dimethylbenzoic Acid as a commodity, we treat it as a specialty product whose reliable supply can make or break larger projects. This mindset has brought industry partners back to us after trying “just-as-good” sources and experiencing unwelcome surprises.

    Every Step Counts: Production, Packaging, and Support

    Chemical manufacturing means more than running reactors and collecting solids. Success shows in the little details: lining fiber drums by hand to prevent contamination, checking seals for integrity before shipping, and recording temperature logs when shipping in changing seasons. On several occasions, clients have reported damage from environmental stress—so we responded by investing in insulated warehouse storage and improved double-layer bagging for sensitive cargos. We respond to requests for lot-specific retests without hesitation, understanding that unexpected batch behavior requires quick, open communication.

    Feedback loops drive continuous improvement. By tracking small customer complaints—about dust, about a slightly sticky bag, about a delayed analytical report—we identify bottlenecks and areas to address. Our technical team stays available both by phone and on-site for troubleshooting, whether it involves questions on dissolution, reactivity with other reagents, or cleaning protocols after use. Many of our repeat clients return for this open line, knowing that accountability remains long after payment clears.

    Green Chemistry and Process Safety

    Environmental and worker safety carry real weight in specialty synthetic chemistry. Years ago, we transitioned away from outdated solvents and optimized workup stages to minimize hazardous waste. By shifting to closed-system filtration and improved solvent recovery, we substantially reduced emissions and limited operator exposure. These investments paid off: our ability to demonstrate compliance has won the trust of customers facing their own audits and regulatory checks. The downstream benefit goes beyond good practice—it means fewer regulatory headaches for those relying on our supply.

    We also support partners developing greener processes by offering detailed impurity profiles, helping chemists reduce reliance on hazardous reagents for final purification. Researchers focusing on sustainability have told us that upstream contaminant reduction saves both time and resources. Continual data collection over years allowed us to further tighten process parameters, keeping unwanted byproducts low enough that many partners simply skip secondary purification, bringing real energy and solvent savings.

    What We Know from Real-World Projects

    Direct work with end users offers insights that marketing materials cannot. A pharmaceutical client running into mystery peaks on an HPLC found the origin—parts per million of a dimethyl isomer—from a single step in our process. Because we could access archived batch data and analytical run histories, we quickly identified the root cause and revised our purification sequence. Later, this client shortened their development cycle and eliminated several previously mandatory re-analysis steps, all because of fast, transparent communication supported by reliable data.

    In another case, a client in specialty pigment manufacturing faced unusual color drift in their end product. By sending technical staff to their production site, we determined the interaction stemmed from micro-trace lot-to-lot differences in our acid’s purity. Adjusting precipitation and drying parameters on our end brought the issue under control. These experiences shape the product we make, influencing process tweaks and technical instructions we share with future partners. We do not treat these encounters as “trouble tickets”—every technical discussion leaves our process more robust.

    Resilience in the Supply Chain

    In years of unpredictable shipping and raw material shortages, the value of manufacturing your own product becomes clear. Import disruptions, regulatory changes, and shipping delays all impact delivery to end users. Maintaining a full pipeline—holding backup stocks of key raw materials and finished goods—reduces panic rush orders and lets customers count on steady supply year-round. We have worked through emergency scenarios, sometimes producing off-hours to fill shortfall, believing that meeting customer commitments comes before paper profits.

    Control of the manufacturing chain also enables us to respond quickly to requests for documentation, extra testing, or custom packaging. As partners move toward stricter process controls—a requirement for new drug approvals, among other things—we keep detailed records and can produce custom statements on residual solvents, allergen risks, or compliance with regional chemical directives. We do not claim perfection in every scenario, but we have learned that owning the source of our product brings more predictability, more improvement opportunities, and fewer chain-of-custody mysteries.

    Looking Ahead: Innovation Informed by Feedback

    We focus on continuous innovation, both in product purity and in service experience. Direct, forthright communication with users remains just as important as advances in chemical yield or cost savings. Regular visits to customer plants reveal problems not visible from a laboratory bench. By gathering real-world complaints—big and small—we find the direction for upgrading equipment, retraining staff, or experimenting with new process improvements.

    Upcoming development directions include lowering energy loads during drying, expanding real-time process monitoring, and integrating predictive analytics for batch quality. Our R&D unit studies subtle changes in reaction kinetics and impurity trends, aiming to further reduce off-lot variation. Our regular client briefings cover not just delivered product specs, but process improvement updates backed up by data and case studies. This culture of honest exchange, field-tested solutions, and reproducible quality grows out of years of direct, accountable manufacturing.

    Commitment Rooted in Daily Practice

    Customers use our 2-Amino-3,5-Dimethylbenzoic Acid to build complex molecules—their scientific progress, product lines, and reputations all tie back to simple, repeatable raw materials. As a manufacturer working at industrial scale, we have seen thousands of small improvements: one filter change making solids behave better, one quality check building new trust, one technical visit preventing days of wasted effort. These things compound over time, shaping the product, the service, and the value that only true production experience can provide.

    For us, making this compound is a craft supported by years of practice, shared lessons, and a direct line from day-to-day production to each customer’s lab or line. This connection, built on real transparency, marks the real difference between product made for catalogs and product made for those who’ll stake their work on its reliability.