Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Amino-3,3-Dimethylbutane

    • Product Name 2-Amino-3,3-Dimethylbutane
    • Alias Pinacolylamine
    • Einecs 211-996-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    646138

    Iupac Name 2-Amino-3,3-dimethylbutane
    Molecular Formula C6H15N
    Molar Mass 101.19 g/mol
    Cas Number 15679-16-6
    Appearance Colorless liquid
    Boiling Point 91-93 °C
    Density 0.761 g/cm3
    Melting Point -48 °C
    Solubility In Water Miscible
    Flash Point 8 °C
    Pubchem Cid 12036
    Refractive Index 1.415
    Smiles CC(C)(C)CC(N)
    Inchi InChI=1S/C6H15N/c1-6(2,3)4-5-7/h4-5,7H2,1-3H3

    As an accredited 2-Amino-3,3-Dimethylbutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100g amber glass bottle with a secure screw cap, labeled "2-Amino-3,3-Dimethylbutane," includes hazard symbols and handling instructions.
    Shipping 2-Amino-3,3-Dimethylbutane is typically shipped in sealed, appropriately labeled containers, protected from moisture, heat, and incompatible substances. It should be handled as a flammable and potentially irritant material, following all local and international regulations. Proper ventilation, personal protective equipment, and safety documentation must accompany each shipment.
    Storage 2-Amino-3,3-dimethylbutane should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from heat sources and incompatible substances such as oxidizers and acids. Protect from direct sunlight and moisture. Store under inert atmosphere if possible and ensure proper labeling. Keep away from ignition sources, and follow all relevant safety protocols to prevent spills and contamination.
    Application of 2-Amino-3,3-Dimethylbutane

    Applications of 2-Amino-3,3-Dimethylbutane in Industrial Manufacturing

    As a direct manufacturer of 2-Amino-3,3-Dimethylbutane, we supply this specialty amine to multiple downstream sectors. Our customers use this compound to achieve precise synthesis goals in regulated industrial environments. Here we detail key application segments, outlining typical regulatory, formulation, and process requirements for each area.

    1. Pharmaceutical Intermediate for Synthesis of CNS Agents

    Many API manufacturers utilize 2-Amino-3,3-Dimethylbutane as a critical building block in the synthesis of central nervous system (CNS) active drugs, especially those involving substituted amine groups. It participates in multi-step organic syntheses, serving as a protected amine source or as an intermediate for the introduction of branching side chains. Target molecules include drugs developed for depression, anxiety, and seizure disorders, where structural diversity in the alkyl chain is required. Our product’s traceability, impurity profile, and batch-to-batch consistency are crucial to downstream GMP compliance.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 210/211 (US FDA cGMP for finished pharmaceuticals)
    • European Pharmacopoeia Monograph Quality Standards for API manufacturing
    • USP-NF General Chapter on Pharmaceutical Excipients

    Typical usage ratio

    • Found in 1.5–3.2 molar equivalents per step, adjusted based on target API yield and desired side-chain branching.
    • Final ratio determined by stoichiometry in API synthesis route, as controlled by process R&D and regulated by DMF submission.

    Downstream process integration

    • Charged as a reagent in early- or mid-stage condensation reactions with activated aromatic or heterocyclic cores.
    • Used during amination, alkylation, and subsequent purification operations in GMP reactors with validated cleaning protocols.
    • Typical integration before final hydrolysis and salt formation steps.

    Final product types

    • Chiral and achiral CNS APIs including branched amine derivatives.
    • Advanced pharmaceutical intermediates registered in Type II DMFs.
    • Pipeline drug candidates for CNS-related indications.
    • Stabilized active pharmaceutical compounds with tailored solubility.

    2. Custom Synthesis of Agrochemical Actives

    Our material supports the custom synthesis of next-generation crop protection agents, especially herbicides and insecticides with branched alkyl substituents. Agrochemical companies employ it to generate intermediate ketones, amides, or carbamates by introducing structural bulk, enhancing environmental persistence and selectivity. Trace amine control and impurity management are essential, considering regulatory scrutiny during product registration and export.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Quality Management Systems for chemical synthesis
    • Regulation (EC) No 1107/2009 for plant protection product approval (EU)
    • US EPA OPPTS Guideline Series for product chemistry

    Typical usage ratio

    • Common range of 2–5% by weight in reaction mixture for condensation or alkylation steps.
    • Adjusted for scale-dependent conversion efficiency and target impurity profile.

    Downstream process integration

    • Introduced during early intermediate synthesis stages, such as nucleophilic amination of halogenated aromatic systems.
    • May be neutralized or converted before final formulation into technical concentrates or emulsifiable concentrates.

    Final product types

    • Amide- and carbamate-based herbicides with improved stability.
    • Active ingredient intermediates for systemic insecticides.
    • Custom agrochemical blocks for R&D or registration dossiers.
    • Specialty crop protection agents for export registration.

    3. Synthesis of Performance Polymer Modifiers

    Performance polymer producers add 2-Amino-3,3-Dimethylbutane to introduce controlled alkyl branching and amine functionality into specialty polyamides and polyurethanes. The molecule plays a role as a chain modifier, imparting flexibility, heat resistance, and moisture barrier properties. Process control over the monomer-to-amine ratio is critical to achieving final resin performance attributes required by automotive, electronics, and packaging industries. Purity assessment and residual amine testing remain integral to final product certification.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for polymer manufacturing
    • ISO 9001:2015 and ISO 14001:2015 (QMS and EMS for chemical plants)
    • UL 94 Flammability Standard for polymer films and parts
    • RoHS (2011/65/EU) for electronic material applications

    Typical usage ratio

    • Ratios typically between 0.7–1.2% by total monomer mass for chain modification.
    • Precisely weighed as dictated by final property targets such as flexibility and thermal aging resistance.

    Downstream process integration

    • Integrated as a component in the polycondensation or prepolymerization steps for reactive extrusion or batch processing.
    • May be used in melt-phase addition for inline production of thermoplastic resin filaments.

    Final product types

    • High-temperature resistant polyamide engineering resins.
    • Polyurethane foam additives for custom automotive trims.
    • Barrier films for electronics packaging applications.
    • Impact-modified nylon and custom engineering plastics.

    4. Manufacture of Fuel and Lubricant Additives

    Producers of custom fuel and lubricant technology formulate 2-Amino-3,3-Dimethylbutane as a specialty co-monomer in fuel detergent and deposit control additive packages. Its branched alkyl amine structure helps improve the cleanliness of fuel injectors and intake valves, while also stabilizing lubricant blends against oxidative decomposition. Additive design requires full composition disclosure and evidence of minimal sulfur and metal content in all supplied lots.

    Industry compliance standards

    • ASTM D4953 for gasoline detergent additive performance
    • SAE J183 for engine oil standardization
    • ISO 22241 for diesel fuel additive compatibility
    • American Petroleum Institute (API) additive quality criteria

    Typical usage ratio

    • Used at 0.03–0.18% by weight in additive package formulations, adjusted for base oil type and test engine requirements.
    • Ratio selected based on cleanliness efficacy test results in finished fuel blends.

    Downstream process integration

    • Added to additive concentrate blending tanks before final blending into base fuel or lubricating oil at the terminal.
    • May undergo quality testing for nitrogen content before dispatch into pipeline distribution systems.

    Final product types

    • Gasoline and diesel deposit control additives for global OEM applications.
    • High-performance engine oil detergents.
    • Multipurpose lubricity enhancers in low-sulfur diesel blends.
    • Aftermarket fuel system cleaning formulations.
    Free Quote

    Competitive 2-Amino-3,3-Dimethylbutane prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Amino-3,3-Dimethylbutane: A Direct Look from the Manufacturer

    2-Amino-3,3-Dimethylbutane stands out among amine products we synthesize in our facility. In our hands, this molecule doesn’t just exist as a chemical name or a substance on a shipment manifest. It’s a carefully engineered component, shaped by experience in fine-tuning organics for industries that demand reliability and predictable behavior.

    Direct Specifications We Stand By

    We control every step in the process of producing 2-Amino-3,3-Dimethylbutane, striving for clear, reproducible standards. The product arrives from our reactors as a colorless liquid, easy to work with under standard laboratory and industrial conditions. Every batch undergoes gas chromatography tests until it hits high purity targets above 99%, letting downstream users focus on their own applications without surprises from contaminants or variable composition. As a saturated aliphatic amine, it brings a unique combination of basicity and steric bulk not mirrored in traditional linear aminobutanes or in more hindered hexamine-type molecules.

    We ship this product with an eye toward material safety and stability. Our team monitors every shipment and regularly checks safeguards on containers and drums, limiting exposure or degradation en route. Our storage guidelines arise from what we’ve seen in our own warehouses: keep it under nitrogen, away from heat and oxidizers, and usual headaches of amine handling—volatile amines sometimes seem like they want to make your day difficult, but not this one if you pay attention.

    Application Insights Straight from Our Production Floor

    Our customers in pharmaceuticals often ask about the practical utility of 2-Amino-3,3-Dimethylbutane. We see chemists picking it for building blocks in medicinal chemistry, especially for molecules that need conformational restriction or increased metabolic stability. That methyl branching offers both benefits: it helps keep the chain from rotating freely and blocks routes for unwanted oxidation, letting final products stay around longer in biological testing.

    In our direct conversations with agrochemical developers, the amine’s bulk makes it a solid option in new formulation work where unwanted reactivity must be kept in check. Its structure provides steric shielding, minimizing side reactions, and making it suitable for fine-tuning active ingredient frameworks. It fits well for anyone looking to get away from the limitations of straight-chain amines that oxidize too fast in field conditions or degrade during formulation.

    Experienced Differences from Other Amines

    Let’s draw a line between this molecule and the more conventional aminobutanes or cyclohexylamines that flood the global markets. 2-Amino-3,3-Dimethylbutane’s two methyl groups off the third carbon change everything. We’ve run both kinds through the same pilot-scale syntheses and watched their reaction profiles. Linear aminobutanes may start out easier to handle when your goal is general basic amine chemistry, but they fall short in applications that punish instability or allow for metabolic breakdown.

    We fielded a project last winter building precursors for a complex drug molecule. Straight-chain aminobutanes kept picking up oxidized byproducts—every run, loss rates climbed, and purification turned into an exercise in patience. Swapping in the branched amine, loss rates halved and impurity profiles dropped to background levels. It changed the economics of the project for our client and for us. These aren’t theoretical gains—they come out of liters we poured, columns we packed, and reaction setups we watched turn from colored to clear on a late shift.

    In polymer chemistry, technicians from our customer base confirm the value of sterics offered by 2-Amino-3,3-Dimethylbutane. Conventional diamines sometimes introduce unwanted cross-linking or chain flexibility that shows up in final properties as brittleness or loss of thermal stability. By contrast, the bulk and restricted rotation of this amine blocks collapse or excess branching, opening new windows for modifying polymer characteristics. We’ve worked personally on adhesives and resins where conventional amines yielded unpredictable setting times or incompatible end-uses. Once we moved to the dimethylbutane core, formulation headaches faded—the resin set more reliably, and performance data ran tighter batch-to-batch.

    Our Manufacturing Focus—Not Just a Commodity

    We have seen how attention to subtle variables pays off for this compound. Hydration and purity management underpin every run; the difference between a smooth shipment and a call-back with quality complaints starts at our process control consoles. Every container we load gets checked for moisture because amines love to pick up water, and someone downstream might build a catalyst or an active ingredient off our base. Skipping this step isn’t an option.

    We source starting materials from trusted supply streams—tried, true, and audited. This is not a corner for shortcuts; unchecked upstream variability multiplies into big swings in downstream reactivity and customer satisfaction. Old experience with less consistent sources taught us this lesson the hard way. That’s why we maintain our documentation, run extra controls, and verify every supply line with more than just certificates of analysis. The reputation of a product like 2-Amino-3,3-Dimethylbutane isn’t built from advertising copy—it comes from reliable chemical performance and direct conversations with people who put it into real-world applications.

    Supporting Real-World Applications—Lessons from the Field

    In the years since we began large-scale synthesis of 2-Amino-3,3-Dimethylbutane, we’ve gathered feedback from researchers scaling pilot batches into ton-scale medicinal work up to those blending hundreds of kilograms in industrial reactors. Out of these hundreds of runs, common pain points emerge: solvent compatibility, stability under various pH, risk of unwanted byproducts, and formulation challenges in aggressive industrial settings.

    Pharmaceutical teams value the way branched methyl groups reduce reactivity with ambient oxygen and cut down on secondary amine formation during storage. We’ve sent sample runs to analytical labs, measuring shelf life and decomposition rates across a spectrum of temperatures. Where more reactive amines degraded and discolored, the dimethylbutane core stayed transparent and pure for far longer, reducing inventory loss and headaches in scale-up programs.

    In agricultural labs, the shift toward greener chemistry keeps moving research teams away from volatile, fast-degrading amines. The stability and slower breakdown rate of 2-Amino-3,3-Dimethylbutane fits these trends. We’ve seen it persist through long sunlight exposures and in field blends that punish lesser molecules. The team at one mid-size agrochemical partner noted savings in waste management alone after moving to this amine, simply because fewer byproducts meant smaller disposal volumes—a real win for their operating costs and compliance efforts.

    Hands-On Handling and Storage

    Safe handling comes from experience, not just procedure sheets. We’ve learned that vigorous agitation or careless decanting of the amine increases vapor exposure risk and opens it up to moisture pick-up. We train our staff and provide handling notes to customer teams, sharing insights for maintaining colorlessness and limiting amine smell that can otherwise linger in storage areas. Our recommendations build on what we’ve seen in our own warehouses and customer sites, not just what comes out of handbooks.

    For longer-term storage, routine control of temperature and dryness pays dividends. Our stockroom logs show that product held in dry, inert gas-flushed containers stays on-spec for months, while material in air-exposed drums can develop off-notes or drop to marginal assay values. Teams adjusting to this product see a difference in shelf life, even with the relatively robust structure of the molecule. These are lessons learned in our bulk warehouses, not just in the brochure notes.

    Process Advantages—From Reaction Efficiency to Purification

    Large-scale users focus not only on the characteristics of the amine but on the way it interacts with the rest of the synthetic process. In hydrogenation and reductive alkylation steps, the sterics of 2-Amino-3,3-Dimethylbutane alter reactivity, often reducing unwanted side reactions like oligomerization or ring closure that plague basic, unhindered amines.

    Analytical runs in our facility showed how this product’s branched structure guides selectivity, allowing for precise additions, especially in constrained reaction environments. For one of our regular pharma customers, that meant fewer purification steps and a lower solvent load, smoothing out both cost management and downtime. This isn’t a benefit you see on spec sheets—it shows up in day-to-day line efficiency and in the number of process alarms and batch recalls.

    Environmental Perspectives Gained from Our Own Processes

    Current regulatory frameworks push for cleaner, lower-impact chemicals in every supply chain. From our facility, we monitor waste streams and emissions for each product line, including 2-Amino-3,3-Dimethylbutane. Its reduced volatility compared to some smaller-chain amines shaves points off emissions calculations, and closed-loop solvent recovery makes for easier compliance reporting, both for us and for customers handling bulky orders on-site.

    In our waste audits, the stability of this amine leads to lower formation of off-odor amine derivatives and fewer issues in water treatment compared to volatile secondary amines or poorly controlled monomethylbutyl formulations. By selecting and running cleaner chemistry, we sidestep regulatory headaches and support environmental standards both locally and for our downstream clients tracking lifecycle metrics in their own audits.

    Our Experience on Improving Efficiency and Productivity

    As a manufacturer, we constantly revisit our syntheses to drive productivity. One lesson comes from the reduced need for overpurification—2-Amino-3,3-Dimethylbutane’s inherently stable character limits the build-up of dark, resinous byproducts common with other aminobutanes. Fewer purification runs means shorter cycle times and less solvent use, aligning well with both cost pressures and green chemistry initiatives.

    We track process yields and material balances batch by batch. Sequential improvements in purification protocols have come from hands-on troubleshooting—a technician swapping out aging column material, a chemist adjusting flow rates after spotting emulsions, or the night shift catching anomalous data spikes on the inline GC. These day-to-day efforts reflect on the final product’s consistency, and we pass on tips that support our customers’ ramp-up runs, offering troubleshooting not off a script, but from lived experience.

    Supporting R&D with Real Samples and Data

    Teams trialing new molecules need more than a batch of product—they need access to detailed behavioral profiles. Our R&D team works alongside customers to run small-scale syntheses, sharing data on yields, side product formation, and long-term stability. For 2-Amino-3,3-Dimethylbutane, we support research teams with practical advice: optimal temperatures for storage, compatible solvents that minimize hydrolysis, and real notes on what to expect during scale-up.

    One collaborative project with a biotechnology lab stands out: initial trials with off-brand samples led to inconsistent coupling rates, traced back to low-level impurities. Once we substituted our in-house material—tracked from start to finish—the results stabilized, yields increased, and analytical data ran clean. These partnerships give both sides a deeper understanding of what separates a commodity product from one that supports breakthrough chemistry.

    Our Everyday Take on Quality and Trust

    Anyone working in fine chemicals knows that trust builds slowly and can break quickly. Our quality checks for 2-Amino-3,3-Dimethylbutane come from decades of running routine and stress tests, holding samples, and sometimes shipping product we know will be tested to the limit in formulation labs. We see the same pattern in every successful partnership: open discussion, quick problem-solving, and continuing product feedback.

    We keep our ears open for pain points—be it odors, degradation issues after long storage, or new application hurdles. Every complaint or suggestion loops back to our production notes. Our teams conduct regular internal audits, not because regulators insist, but because missed details in chemical manufacture often lead to breakdowns in customer trust. Success, for us, comes down to open communication and the willingness to adapt.

    The Difference Direct Manufacturing Makes

    Our approach to 2-Amino-3,3-Dimethylbutane springs from first-hand experience. Third-party handlers or resellers may see this product as one item in a catalog of basic chemicals. From the inside, we measure and care about every step—resource sourcing, in-process controls, final product checks, packaging, and shipment tracking. That attitude shapes our reputation and our product’s performance in the field.

    Day after day, we see the impact of direct engagement: quick answers to technical queries, willingness to share historical data, and support that doesn’t end with a shipment leaving our gates. Teams that buy from us get a partner who shares in the stakes of their results—successes, setbacks, and continual improvements, all from real chemical practice, not from marketing copy.

    Long-Term View: Building Value Beyond the Label

    Looking back at the role 2-Amino-3,3-Dimethylbutane plays for both us and our customers, it becomes clear why thoughtful manufacturing adds distinct value. From its detailed behavior in tough chemical environments to the trust built through transparent handling, this amine has moved beyond simply being another raw material in a supply chain. It’s a product shaped by feedback, refined in practice, and constantly supported by a team that stands behind every shipment.

    We welcome ongoing feedback, whether it comes through a chemist’s observation, a process engineer’s note on solvent requirements, or a formulator’s questions about new applications. Each piece of experience adds to the collective knowledge that drives better synthesis, design, and ultimate performance. For manufacturers who care about the quality and repeatability of their chemistry—as we do—choosing 2-Amino-3,3-Dimethylbutane from a dedicated producer offers more than just a specification. It provides confidence built through thousands of runs, countless tests, and a genuine commitment to doing the job right.