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2,8-Dibromodibenzothiophene

    • Product Name 2,8-Dibromodibenzothiophene
    • Alias DBDBT
    • Einecs 211-162-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    878002

    Cas Number 51112-32-8
    Molecular Formula C12H6Br2S
    Molecular Weight 358.05 g/mol
    Appearance White to light yellow solid
    Melting Point 158-160 °C
    Purity Typically ≥98%
    Synonyms 2,8-Dibromo-dibenzothiophene
    Solubility Insoluble in water; soluble in organic solvents
    Smiles Brc1ccc2sc3cccc(Br)c3c2c1
    Inchi InChI=1S/C12H6Br2S/c13-7-1-3-9-11(5-7)15-10-4-2-8(14)6-12(9)10/h1-6H

    As an accredited 2,8-Dibromodibenzothiophene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2,8-Dibromodibenzothiophene is supplied in a 5-gram amber glass bottle with a secure screw cap, labeled for safety.
    Shipping 2,8-Dibromodibenzothiophene is shipped in tightly sealed containers to prevent moisture and light exposure. The chemical is packed according to hazardous material regulations, clearly labeled, and cushioned to avoid breakage during transit. It is typically transported by ground or air, in compliance with local and international safety guidelines.
    Storage 2,8-Dibromodibenzothiophene should be stored in a tightly sealed container, protected from light and moisture, in a cool, dry, and well-ventilated area. Keep away from incompatible materials such as strong oxidizing agents. Ensure containers are clearly labeled and stored according to established chemical safety protocols. Access should be limited to trained personnel wearing appropriate personal protective equipment.
    Application of 2,8-Dibromodibenzothiophene

    Applications of 2,8-Dibromodibenzothiophene in Industrial Manufacturing

    2,8-Dibromodibenzothiophene serves as a specialty intermediate in several high-tech and chemical transformation industries. Our materials undergo rigorous quality control to meet the demands and regulatory requirements of advanced manufacturers worldwide. Below, we detail key downstream industrial scenarios that rely on this compound, focusing on real-world integration specifics and sector mandates.

    1. Organic Semiconductor & OLED Material Synthesis

    Leading manufacturers of organic semiconductors source 2,8-Dibromodibenzothiophene as a core building block for constructing fused aromatic systems. During molecular engineering of emissive and conductive layers in OLED panels, our compound delivers high reactivity and substitution selectivity. Its dibromo functionalization enables direct cross-coupling, facilitating synthetic precision and scalability for electronics-grade performance.

    Industry compliance standards

    • RoHS (Restriction of Hazardous Substances Directive, EU 2011/65/EU)
    • REACH (EC 1907/2006) registered usage and safety documentation
    • IEC 61249-2-21 for halogenated materials in electronic applications
    • IPC-6012C acceptance for base materials in advanced PCB and display manufacturing

    Typical usage ratio

    • Applied at 2–6 mol% as precursor in Suzuki or Stille coupling reactions for forming conjugated backbones, adjusted for target polymerization degree

    Downstream process integration

    • Introduced at monomer synthesis stage, followed by purification and direct polymerization steps to form light-emitting or charge-transport layers before device fabrication

    Final product types

    • OLED display panels
    • Organic photovoltaic cells
    • Flexible printed circuits for wearable electronics
    • Advanced organic integrated circuits

    2. Pharmaceutical API Development (Heterocycle Synthesis)

    Pharmaceutical innovators use this compound as a brominated thiophene scaffold for constructing advanced heterocycles. In particular, its reactivity profile supports the production of complex intermediates destined for targeted oncology and CNS active pharmaceutical ingredients. Synthesis conditions optimize yield while allowing precise control over functional group transformations in regulated GMP environments.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for APIs)
    • USP-NF monograph compliance for input chemical quality
    • European Pharmacopoeia safety and impurity evaluation
    • FDA 21 CFR Part 210/211 for drug substance processing

    Typical usage ratio

    • Commonly used at 0.1–2 molar equivalents, adjusted based on heterocycle structure complexity and downstream yield optimization

    Downstream process integration

    • Transforms during early-stage intermediate synthesis, either by directed lithiation, cross-coupling, or palladium-catalyzed cyclization, leading to advanced core fragments for API assembly

    Final product types

    • Investigational new drugs (INDs) with dibenzothiophene cores
    • Reference drug intermediates for antineoplastic agents
    • CNS-targeted small molecule APIs
    • Advanced intermediates for custom synthesis outsourcing

    3. Specialty Polymer Additive Formulation

    Materials engineers leverage this compound to introduce flame retardant attributes and improved thermal stability into specialty polymers. In formulations such as high-performance polyimides, polyesters, and epoxy resins, the dibrominated aromatic structure supports regulated thermal degradation thresholds while maintaining mechanical standards required in electrical insulation and aerospace composites.

    Industry compliance standards

    • UL 94 Vertical and Horizontal Flame Classification (V-0, V-1, HB ratings)
    • EN 45545-2 (Railway applications – Fire protection)
    • ASTM D2863 Limiting Oxygen Index for flame retardancy
    • ISO 1043-4 identification for polymer flame retardant additives

    Typical usage ratio

    • Typically incorporated at 1–7 wt%, with adjustment depending on base polymer chemistry and target LOI or V rating requirements

    Downstream process integration

    • Compounds directly blended into polymer matrix during masterbatch preparation prior to extrusion, molding, or casting processes

    Final product types

    • Insulated cables for telecom and electronics
    • Aerospace-grade composite laminates
    • Rail transport seating and wall panels
    • Epoxy resins for printed circuit boards

    4. Sulfur-Containing Ligand Synthesis for Catalysts

    In advanced catalyst manufacturing, practitioners employ this raw material to design sulfur-rich ligands with controlled geometry and electronic properties. Precise dibromination enables targeted modifications for metal complexation, supporting catalyst libraries used in industrial hydrogenation, C–C coupling, and hydrodesulfurization processes. Integration into ligand synthesis ensures batch consistency critical for catalytic activity and downstream performance.

    Industry compliance standards

    • ISO 9001:2015 for consistent ligand intermediate production
    • Responsible Care® initiative for chemical handling and environmental safety
    • EC Regulation No 1272/2008 CLP for chemical labeling and classification
    • Internal QC specifications for trace impurity levels and ligand purity

    Typical usage ratio

    • Reacted at stoichiometric levels, generally 1–1.5 equivalents relative to ligand backbone, with fine-tuning per metal coordination requirements

    Downstream process integration

    • Engaged at the initial stage of ligand preparation, enabling bromine substitution or metalation prior to catalyst complex assembly and deployment in reactors

    Final product types

    • Homogeneous catalysts for asymmetric synthesis
    • Metal–sulfur complex catalysts for petrochemical processing
    • Palladium-based C–C coupling catalysts
    • Ligand standards for catalyst R&D and QC reference
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    Certification & Compliance
    More Introduction

    2,8-Dibromodibenzothiophene: A Chemist’s Perspective from the Factory Floor

    Getting to Know 2,8-Dibromodibenzothiophene

    2,8-Dibromodibenzothiophene has built a reputation as a specialty building block for anyone working at the intersection of organic synthesis and specialty materials. Our team has been producing this compound for years, and our direct experience brings us into long-term partnerships with researchers and process chemists transforming their ideas into practice. The compound’s structure, based on the dibenzothiophene core brominated at the 2 and 8 positions, creates a molecule sought after by both academic and industrial innovators. In our hands, the process becomes more than chemistry; it becomes an investment in reliability and repeatability—two things every chemist values when budgets and schedules come under pressure.

    Details from the Factory Floor

    In our production plant, the team works with strict controls to achieve a high-purity version of 2,8-Dibromodibenzothiophene. The solid, pale yellow appearance is almost a trademark of a well-executed batch, a difference that reveals itself at a glance to experienced eyes. On analysis, our specification delivers a purity that typical users in pharmaceutical and advanced materials research find reliable. This level of control relies on efficient bromination and optimized crystallization. Our scale-up experience allows us to supply batches anywhere from gram-scale pilot runs for proof-of-principle labs, right up to multi-kilo quantities preferred by larger projects.

    People ask us about shelf life and storage fairly often. Our practice, developed after more than a decade working with aromatic bromides, keeps the product dry and protected from light, so the reactive bromines don’t go astray. In direct customer feedback, minor details like reduced dust and proper granule sizing stand out as factors that let chemists work without frustration. We pay close attention to these finishing steps, knowing how tiny quality shifts can affect later reactions.

    Where 2,8-Dibromodibenzothiophene Shines

    Working alongside researchers, we see this molecule most often at the heart of organic electronics, some pharmaceuticals development, and certain polymer precursors. Its two bromine atoms open doors for cross-coupling chemistry—palladium-catalyzed Suzuki, Stille, or Negishi couplings all run efficiently if your starting material provides consistently reactive bromines. With our batches, end-users describe sharper, more predictable yields during these coupling steps, reducing problems with batch-to-batch variability that can eat up resources in the scale-up phase.

    Engineers and material developers also prize the rigidity and planarity of the dibenzothiophene backbone, especially for building conjugated polymers. This rigidity is hard-won; the aromatic fusion makes for more stability in finished electronic materials, such as semiconducting polymers, OLED layers, or organic photovoltaic cells. The twin bromines at the 2 and 8 positions lend themselves to selectivity, letting the molecule serve as a reliable platform for further elaboration. If you are building ladder polymers or high-performance thin films, you’re most likely looking for the purity and positional accuracy that our production provides.

    Comparing to Related Dibenzothiophene Compounds

    Many who contact us have already worked with mono-brominated or other halogenated dibenzothiophene derivatives. The question comes up: what does 2,8-dibromo bring compared to 2-bromo, 3,7-dibromo, or even the chlorinated and iodinated analogs? From a synthetic perspective, the 2,8-positions push the reactivity map outwards. This arrangement creates a scaffold that can undergo further substitution selectively, particularly in cross-coupling or lithiation sequences. In some projects, this specific geometry allows design of more linear polymer chains or tuning of electronic communication between adjacent units.

    Pure 2,8-dibromodibenzothiophene avoids certain byproduct or regioisomer headaches present when mixtures are allowed to form during less-controlled synthesis. At the bench or in continuous flow setups, users have come back to us reporting cleaner reaction profiles and fewer downstream purification steps when using our material. Simpler processes have ripple effects throughout a project, from analytical savings to reduced waste and energy use.

    We have handled requests for both 2,8- and other dihalogenated variants. In every case, those working with the dibromo compound point out distinct reactivity in cross-coupling and unique end-use properties in polymers and small molecule semiconductors that differ from their iodo, chloro, or mixed-halogen cousins. The chemical and physical footprint—weight, leaving group ability, steric profile—lands this material in projects where control and predictability matter more than anything.

    Quality, Traceability, and Feedback from Chemists

    Chemists using halogenated intermediates remember the headaches that can come from inconsistency: changes in lot-to-lot impurity profiles, residual starting material, or traces of metal catalysts lingering from synthesis. Our approach aims to shut down these issues before the product leaves the plant. Each batch of 2,8-dibromodibenzothiophene undergoes analytical scrutiny—NMR checks for positional purity, mass spectrometry, and optimized GC or HPLC (depending on the project’s sensitivity to minor components). We have learned through experience that direct conversations with chemists matter. That’s why our in-house team fields questions not just on technical sheets, but on practical solvent compatibility and scale-up anecdotes.

    Supply chain challenges around specialty brominated aromatics are no secret, especially as regulatory demands tighten for bromine sourcing and handling. We've invested in safe, contained bromination processes and recovery systems for unreacted bromine, which reduces both environmental burden and cost uncertainty. We maintain full traceability of incoming raw materials, and deliver clear, unambiguous paperwork that end users and auditors can check at any point in their workflow.

    Supporting New Research and Industrial Scale-Up

    In recent years, our biggest increase in orders has come from teams scaling up novel organic electronic devices—novel field-effect transistors, photovoltaic materials, and dye-sensitized solar cells. The demand stretches from academic groups perfecting device recipes right through to pilot plants testing hundreds of grams at a time under industrial conditions. We have worked closely with several research groups to adapt batch sizes, increase washing and drying iterations, and tweak our packaging to suit glove box transfer or high-throughput automated weighing systems. Our customers have shared how these little adjustments decrease the risk of contamination and keep device yields stable.

    Alongside electronics, some groups probe new pharmaceutical intermediates based on the dibenzothiophene skeleton, aiming for unique activity in antifungal or antibacterial projects. While this class of chemistry moves slowly, the need for reproducible purity never disappears. Feedback on our production batches has often centered on the consistency of bromine reactivity—the difference between a reproducible medicinal scaffold and a costly hit-and-miss effort.

    We keep communications open with material scientists asking about ways to optimize structure-property relationships in oligomers, copolymers, or ladder-type macromolecules. Every conversation about dibromodibenzothiophene’s role in overcoming charge mobility bottlenecks, thermal stability needs, or purity requirements that underpin reliable structure elucidation keeps us sharpening our process and analytical checks. Collaborative development between supplier and end-users means faster troubleshooting, reduced error rates, and better overall project outcomes.

    Environmental and Handling Considerations

    Providing safe, manageable solutions for halogenated compounds has become a bigger focus across the industry. For us, this starts by minimizing operator exposure—moving from drums and open air handling toward sealed packaging in controlled atmospheres. Our shift reduces volatilization losses, accidental exposure, and time-consuming cleanup. Downstream, end users appreciate that they can transfer the product into glove boxes or nitrogen-filled environments with minimum hassle, cutting risk at every step.

    We also focus keenly on recycling and disposal. Bromine recovery and handling waste streams remain high-priority engineering problems. We have invested in closed-loop systems that track and reuse bromine wherever possible, both for cost control and regulatory compliance. Users with in-house disposal agreements gain reassurance that waste profiles remain stable, and government auditors value documented steps to reduce bromide and byproduct residues.

    Our teams pay attention not just to chemical fingerprint, but also particle size, flow characteristics, and ease of transfer. Analytical chemists working with automated weighing or robotic synthesis setups have shared how a small tweak in average granule diameter unlocks smoother operation, reduces static-related losses, and keeps automated tracks moving without interruption. This level of process awareness only comes after years of candid feedback and engineering within live production environments.

    Why Direct Manufacturing Matters

    In an industry where time and cost pressures never let up, manufacturers willing to stay close to their customers reap rewards. Our in-house chemists not only run the plant, but also test and vet every batch. When partners report a yield drop or unexpected impurity, our technical and production teams can rerun quality screens for hidden contamination. These small interventions add up—chemists know their findings receive real attention, not just lip-service.

    Unlike third-party traders or brokers, direct manufacturers control their processes from start to finish. We set raw material sourcing rules, invest in new containment or filtration steps, and tweak synthesis routes based on customer projects without months-long wait times. Several groups we supply have built longstanding trust not just on one-time purchases, but on a pattern of rapid response to tweaks in particle morphology, packaging, or even labeling clarity. This responsiveness keeps research timelines moving in industries where a single week’s delay means missed deadlines or budget overrun.

    Cost always sits at the center of specialty chemical purchasing, but buyers know that bargain options from unclear sources put entire development cycles at risk. Quality drift in halogenated intermediates brings pain that only shows up late, and remediation in downstream stages costs more than buying well-characterized material up front. As a producer, we live the cycle end to end, standing behind every shipment from raw material audit to final shipping record.

    Scaling, Adaptability, and Future Outlook

    The demand for specialty intermediates like 2,8-dibromodibenzothiophene is trending up, especially in energy conversion, optoelectronics, and advanced polymer research. Projects in these areas rarely fit into neat purchasing cycles: academic consortia run small screens, followed by rapid expansions, while industrial testbeds want hundreds of grams yesterday. Our facility is set up for flexibility, moving quickly from setup to packaging changes and allowing incremental throughput expansions. Over the past few years, our switches between different batch sizes, drying methods, and shipment logistics have kept our users moving, even with increasing global volatility.

    New regulations tighten expectations around brominated intermediates. As legislation evolves to cover the origins, uses, and tracking of every kilogram of halogenated compound, direct manufacturing oversight becomes non-negotiable. We partner with compliance specialists and regularly update training for all operators, making sure our people and supply lines stay ahead of regulatory shocks. Chemists can therefore work with less paperwork burden, relying on up-to-date certifications and clean audit trails for every batch.

    Closer ties between specialty chemical producers and high-tech end users push manufacturers to go beyond the basics, adding expertise in not just the product, but its applications and implications. In a market shifting steadily toward electronic devices, sensors, and light-based technologies, we expect the role of 2,8-dibromodibenzothiophene to grow, driving further advances in both chemical processes and the finished technologies built upon them. Our place as a direct manufacturer assures partners of adaptability, transparency, and above all, the confidence that the molecules they rely on will do their job—no costly surprises, no silent failures.

    Final Reflections from the Manufacturer’s View

    Making and supplying 2,8-dibromodibenzothiophene means more than meeting purity specs or loading boxes on a truck. It means engaging in the daily challenges of modern chemistry, learning from people at the front lines of development, and putting those lessons to work in every batch we ship. For the material scientist optimizing new polymers, for the chemical engineer targeting device-grade purity, or the process chemist scaling up a new therapeutic pathway, these details matter. Our experience confirms the real-world value of direct manufacturing: traceable, responsive, and always open to the unpredictable realities of chemical innovation. Those we serve deserve nothing less.