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2,7-Dibromonaphthalene

    • Product Name 2,7-Dibromonaphthalene
    • Alias 2,7-Dibromonaphthalin
    • Einecs 216-130-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    715842

    Cas Number 582-18-1
    Molecular Formula C10H6Br2
    Molar Mass 313.97 g/mol
    Appearance White to off-white solid
    Melting Point 142-145 °C
    Boiling Point 367 °C
    Density 1.89 g/cm³
    Solubility In Water Insoluble
    Refractive Index 1.674
    Flash Point 180 °C
    Smiles Brc1ccc2ccc(Br)cc2c1
    Inchi InChI=1S/C10H6Br2/c11-7-3-1-5-9-6-2-4-8(12)10(7)9/h1-6H
    Pubchem Cid 119932
    Ec Number 209-487-2
    Logp 5.11

    As an accredited 2,7-Dibromonaphthalene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 25g 2,7-Dibromonaphthalene comes in a sealed amber glass bottle, labeled with hazard symbols, product information, and safety instructions.
    Shipping 2,7-Dibromonaphthalene is shipped in tightly sealed, chemically resistant containers, typically made of glass or high-density polyethylene. The package is clearly labeled with hazard information and handled as a hazardous material. It is stored and transported in cool, dry conditions, away from incompatible substances, in compliance with regulatory guidelines.
    Storage 2,7-Dibromonaphthalene should be stored in a tightly sealed container, away from light, heat, and moisture. Keep it in a cool, dry, well-ventilated area, separate from incompatible substances like strong oxidizers. Properly label the container and avoid exposure to open flames, as the substance may be combustible. Use appropriate protective equipment when handling and storing the chemical.
    Application of 2,7-Dibromonaphthalene

    Applications of 2,7-Dibromonaphthalene in Industrial Manufacturing

    As a specialized manufacturer of 2,7-Dibromonaphthalene, we supply high-purity material tailored for advanced industrial transformations. The downstream use of this chemical centers on sectors requiring controlled halogenation and conjugated aromatic structures for technical performance. Below, we detail the most relevant application scenarios across major chemical and high-tech manufacturing fields, including regulatory environment, real-world production ratios, integration points, and associated end products.

    1. Organic Semiconductor Intermediates in Electronics Materials

    2,7-Dibromonaphthalene serves as a key intermediate in synthesizing functionalized naphthalene derivatives or extended π-conjugated molecules for organic electronics. Its dibromo positioning is critical in facilitating Suzuki or Stille couplings, enabling the build-out of semiconducting frameworks for applications such as organic light emitting diodes (OLEDs), thin-film transistors, and photovoltaic devices. Electronics material producers rely on tightly-controlled specifications with traceable supply chain records.

    Industry compliance standards

    • IEC 62474 (Material Declaration for Products of and for the Electrotechnical Industry)
    • RoHS 2011/65/EU (Restriction of Hazardous Substances in Electronics)
    • REACH Regulation (EC) No 1907/2006 (Registration, Evaluation, Authorisation and Restriction of Chemicals)
    • ISO 9001:2015 (Quality Management Systems for Material Suppliers)

    Typical usage ratio

    • 0.5–1.8 molar equivalents per coupling reaction, adjusted based on target π-system extension and batch scale
    • Final loading in functional materials: varies 10–30% as co-monomer or subunit in donor-acceptor-type architectures

    Downstream process integration

    • Added in coupling or cross-coupling reactors during fine organic synthesis to attach aryl, alkynyl, or heterocycles
    • Purified as an intermediate, then further derivatized or directly processed into device-grade active layers

    Final product types

    • Organic semiconducting polymers (e.g., poly(naphthalene-alt-thiophene)s)
    • Small-molecule hole/electron transport materials for OLEDs
    • Organic solar cell active layers
    • Thin-film transistor arrays for flexible electronics

    2. Pharmaceutical Intermediate for Specialty APIs

    This compound is employed as a halogenated scaffold for synthesizing advanced pharmaceutical intermediates, particularly those involving multi-step aromatic transformations or targeted halogen exchange. Its brominated positions allow regioselective functionalization, supporting active pharmaceutical ingredient (API) research and scale-up in the oncology and neuroprotection segments. Purity standards and impurity profiles must meet clinical manufacturing needs.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients)
    • USP <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products
    • ISO 13408-1 (Aseptic Processing of Healthcare Products)
    • FDA 21 CFR Part 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals)

    Typical usage ratio

    • 0.9–1.2 mole equivalents in key coupling or cyclization steps depending on the synthesis route
    • Residual levels in API < 0.1 ppm as per pharmacopoeial specifications

    Downstream process integration

    • Employed in the early-to-mid-stage steps of aromatic API synthesis via cross-coupling, cyclization, or substitution reactions
    • Isolated and purified before conversion to subsequent intermediates under GMP workflows

    Final product types

    • Targeted kinase inhibitors (e.g., naphthalene-based oncology compounds)
    • CNS-active pharmaceutical ingredients with naphthyl scaffolds
    • Specialty diagnostic reagents for clinical assay kits
    • Advanced intermediates for radiolabeled pharmaceutical research

    3. Advanced Dye and Pigment Synthesis

    Manufacturers of specialty dyes and pigments use 2,7-Dibromonaphthalene to construct high-performance chromophores with improved stability and custom absorption spectra. The brominated naphthalene acts as a core for subsequent substitution with electron-rich or electron-deficient groups, producing materials for optical filters, complex printing inks, and photoresists. This application demands rigorous control over residual halogen content and color purity.

    Industry compliance standards

    • ISO 18451-1 (Pigments and Extenders Terminology)
    • EN 71-3 (Safety of Toys: Migration of Certain Elements, relevant for pigment safety in consumer products)
    • GB/T 23990 (General Safety Technical Code for Dyes and Pigments)
    • ISO 14001:2015 (Environmental management in pigment production)

    Typical usage ratio

    • 1.0–2.0 molar equivalents per dye synthesis, varying by chromophore design and pigmenting process
    • Final pigment formulation may contain 5–15 wt% of naphthalene-derived unit

    Downstream process integration

    • Dosed at the condensation, substitution, or coupling step, often with metal catalysts for chromophore assembly
    • Intermediate is further processed to finished dye or pigment form with particle size tuning

    Final product types

    • Naphthalene-based organic pigments for specialty paints and coatings
    • Thermal transfer and inkjet printing inks
    • Photoresist colorants for microelectronics fabrication
    • Optical filter dyes used in imaging and sensor devices

    4. Specialty Polymer Building Blocks

    Producers of high-value specialty polymers use this dibrominated aromatic as a monomer or co-monomer for step-growth polymerization, allowing the introduction of rigid, planar structures in the polymer backbone. This enhances mechanical and thermal properties, as well as facilitating precisely controlled electronic and optical traits in engineering plastics and membrane materials. Stringent process validation and impurity control remain mandatory throughout polymer scale-up.

    Industry compliance standards

    • ISO 178 (Determination of Flexural Properties of Plastics)
    • ASTM D638 (Standard Test Method for Tensile Properties of Plastics)
    • ISO 14632 (Thermoplastic Polyester/Polyamide Blends—Process and Test Requirements)
    • ANSI/SOCMA ChemStewards (Responsible Care Management for Chemical Synthesis and Handling)

    Typical usage ratio

    • Up to 20 mol% incorporated during co-polymerization or as end-capper depending on targeted polymer architecture and function
    • Adjustment according to tensile strength, thermal resistance, or dielectric property specifications

    Downstream process integration

    • Fed into controlled polymerization reactors—step-growth or cross-coupling based—for chain construction
    • Material can be isolated as a polymer precursor or directly processed into films, membranes, or molded parts

    Final product types

    • High-glass transition temperature engineering plastics
    • Specialty membranes for gas separation or organic solvent nanofiltration
    • Optoelectronic-grade polymer films
    • Precision-molded parts requiring dimensional stability at elevated temperatures

    5. Reference Standard and Analytical Use in QC Laboratories

    Many analytical laboratories and in-house QC teams use traceable, high-purity 2,7-dibromonaphthalene as a reference material for method validation, instrument calibration, and impurity profiling in naphthalene-derived production lines. Full documentation of purity, isomer content, and stability is necessary for analytical consistency, supporting the development of validated HPLC, GC-MS, and NMR methods that trace residuals or process byproducts in industrial environments.

    Industry compliance standards

    • ISO/IEC 17025 (General Requirements for the Competence of Testing and Calibration Laboratories)
    • USP <1225> (Validation of Compendial Procedures)
    • GLP (Good Laboratory Practice) as defined in OECD Principles
    • Sigma-Aldrich Standard Reference Material protocols for analytical verification

    Typical usage ratio

    • Introduced at 1–100 ppm concentrations, as required by method linearity and instrument sensitivity
    • Spiking levels and matrix selections based on method performance characteristics

    Downstream process integration

    • Used as a system suitability or calibration check in analytical method development
    • Applied in spike/recovery QA/QC workflows for batch release and regulatory reporting

    Final product types

    • Analytical standards for regulatory submissions and inter-laboratory studies
    • Certified reference materials for calibration and validation purposes
    • Spiked quality control samples for ongoing batch purity testing
    • Standard solutions for chromatographic or spectrometric performance testing
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    Certification & Compliance
    More Introduction

    Introducing 2,7-Dibromonaphthalene: Perspectives from a Manufacturer

    From Raw Idea to Finished Product

    Some chemicals reach beyond the role of a mere starting material—they build bridges between science and industry, tackle the gaps between demand and value, and fuel decades of innovation across disciplines. 2,7-Dibromonaphthalene does that on a daily basis in our production facility. Its journey begins with naphthalene isolation and selective halogenation, two operations that have shaped our plant process for years. Compared to preparing mono-brominated or random polybrominated naphthalenes, getting a pure 2,7-dibromo derivative presents unique challenges and rewards.

    Production Experience Matters

    Getting a predictable yield with minimal impurities relies on how batch handling, temperature control, and post-reaction purification are implemented. In our experience, small deviations—be it temperature drifts or subtle changes in agitation—tend to push the process toward unwanted isomers or extra bromination. Not only does this create separation bottlenecks, it adds unnecessary solvent, ultimately driving up energy use in the distillation stages. Quality assurance in this case means constant vigilance on both raw input and operational parameters. Over years of optimization, we have found it’s the attention to seemingly minor variables that determines whether you end up with a sharp melting point and a clean product or spend hours troubleshooting chromatographic tails.

    Understanding the Specifications

    Our 2,7-dibromonaphthalene typically appears as a pale solid with a crystalline structure that passes our in-house purity thresholds using gas chromatography and NMR checks. Consistently, our runs produce narrow melting range material above 80°C. Bromine content analysis is key—a fraction above or below target flags recovery or process error. While regulatory standards define minimum purity, we try to exceed these benchmarks, knowing unreacted naphthalene or off-isomers have consequences downstream, especially for pharmaceutical and electronic applications.

    Batch-to-batch reproducibility is critical. Analysts in our lab track bromine loading, water content, and trace heavy metals. Our recordings show that keeping residual solvents below 0.5% offers better material performance, especially for researchers investing in further synthesis. For certain clients, we also screen for aromatic impurities using UV-Vis analysis, knowing some applications show surprising sensitivity to trace contamination.

    Uses and Real-World Application

    The main value of 2,7-dibromonaphthalene always returns to its reactivity. Through years of feedback from customers and our own internal R&D, the standout use is as a coupling building block for advanced materials. Suzuki-Miyaura and Stille-type cross-couplings flourish when using this compound, thanks to the positioning of the bromine atoms. Researchers and commercial plants synthesize polycyclic aromatic hydrocarbons, liquid crystal materials, and naphthalene-based polymers—all fields where substituent control can make or break purity and properties.

    Our teams have collaborated with electronics companies optimizing organic semiconductor layers. They report that 2,7-dibromonaphthalene delivers cleaner end products with higher charge mobility, compared to less symmetric brominated naphthalenes. In dye synthesis, our product shows fewer side-reactions; this reduces purification load and increases pigment yields. Sourcing this compound directly from a manufacturer—not from a repacker or distributor—lets downstream users gain the benefit of tighter tolerances and a direct pipeline for feedback and process improvement.

    What Distinguishes Our 2,7-Dibromonaphthalene?

    Every plant offers its own version of brominated naphthalene. We have sampled and analyzed commercial lots from global players and noticed that minor process distinctions shape the user experience. Material from our reactors tends to show better lot homogeneity over time, especially with respect to small-molecule contaminants and polymerizable side-products. This outcome owes partly to our method of quenching and crystallization, which we’ve refined across hundreds of cycles. The difference plays out tangibly for customers: their reaction color is more consistent; their downstream purifications are simplified, and their yields, including for customized molecular architectures, often come in closer to calculated targets.

    Another difference stems from how we monitor trace iron, copper, and palladium—often invisible until they poison a catalyst or trigger undesirable side-reactions in delicate molecules. Our techs track trace metal levels using ICP-MS, and we routinely deliver below 10 ppm, preventing polymer discoloration or electronic defects. We don’t take for granted that a batch passes QC because the paper specification looks right; customers often discover that similar grades from other suppliers create downstream headaches that disappear when they switch to ours.

    Shipping and packaging impact how material survives the journey to the lab or factory. We spent years working out a system that reduces contamination and false positives for residual solvents. Our choice of double-sealed, airtight containers, combined with real-time moisture analysis, has cut down on the “clumpy solid” effect that used to frustrate users in humid climates. Direct, transparently packed shipments also eliminate typical warehouse cross-contamination, giving buyers the true output of a chemical plant, not a mystery blend of possibly mismatched origins.

    Not Just a Commodity

    Lots of buyers mistakenly think of this product as a mere raw material, no different from feedstock naphthalene or generic fine chemicals. Real production proves otherwise. If a single lot includes too much 1,5-dibromonaphthalene byproduct, the customer’s coupling chemistry can stall or give impure outcomes. On a larger scale, one contaminated container can upend weeks of production, leading to wasted time and unplanned downtime. We have learned, after years stepping into customer troubleshooting workshops, how 2,7-dibromonaphthalene’s profile changes everything from crystal engineering to spectral analysis.

    The true value comes from how we blend bulk scale with attention to detail. For a dye manufacturer looking for batch-to-batch color consistency, our preparations cut down on rework and testing costs by arriving ready to deploy. In academic labs pushing the limits of molecular electronics, we field questions about the tiniest NMR signals or GC-MS fragments, sometimes consulting on synthetic routes to optimize conditions around our core product’s quirks. Years observing client outcomes convinced us: who makes the material, how it’s handled, and what checks are in place shape project timelines and even patent outcomes in subtle, bottom-line ways.

    Safety, Sustainability, and Process Transparency

    Chemical manufacturing today can’t just focus on what comes out the end of the pipeline. Environmental and personnel safety frame everything we do. Over the last decade, we’ve redesigned our halogenation and crystallization lines to reduce byproducts and minimize organic emissions. This move resulted not just from regulatory shifts but from repeated operator insight that the older systems wasted energy and raw materials. Implementing closed recovery loops for both reagents and solvents now leaves our facility with lower hazard rankings and has translated to measurable energy and water savings.

    Responsible production supports business resilience. After a well-publicized industry incident, we took extra steps in personnel training. Today, every operator and supervisor in our process area knows the specifics of bromine handling and naphthalene dust mitigation. This translates to safer working environments, fewer stoppages, and less risk of downtime—gains our customers rarely see but benefit from every time they order. In-house monitoring does not just meet external audits, it helps maintain a standard we set ourselves, rooted in years striving for both product and process excellence.

    Supply Chain Reliability

    Global logistics add stress to the journey from plant to user, especially when handling specialty chemicals sensitive to both time and temperature. We have watched how breakdowns happen. Several years ago, a major delay at a transit hub put one of our shipments in limbo during summer heat, and the effect on the product’s appearance taught us more than any classroom warning ever could. We responded by refining our packaging and committing to temperature-controlled freight options for critical routes.

    Our scheduling team updates shipment tracking with the same attention they offer to in-plant quality checks. This culture of feedback means we regularly debrief on delivery timelines and damaged materials, linking operational improvements directly to the chemistry itself. We act on insights from global R&D teams, prioritizing uninterrupted supply even when upstream bromine or naphthalene prices fluctuate. Sharing weekly status reports with large clients, our team catches issues early, building trust in an industry sometimes known for opacity and slow communication.

    In the Field: Feedback Loops with Users

    No chemical plant gets better in a vacuum. Relationships with customers give rise to improvements we might never innovate from lab theory alone. Years of technical calls and shared troubleshooting have changed our batch records and sometimes even our equipment design. One routine issue—unexpected thermal decomposition in a client’s autoclave—turned out to be linked to trace solvent presence from our own purification steps. By switching a process condition and adding real-time GC analysis, we solved the issue for every subsequent run.

    We find that customers ranging from university labs to heavily automated multinationals share one desire: predictability. They want to rely on each container behaving as promised, so their teams can focus on making discoveries or hitting production targets instead of wrestling with out-of-spec batches. We answer questions about solubility, compatibility with palladium catalysts, and storage tips, drawing on hundreds of production cycles and test runs. Over time, we have assembled detailed troubleshooting and best-practices guidance, much of it written in response to exact questions and problems in the field.

    Looking Ahead: Keeping Up with Industry Shifts

    Markets for brominated naphthalenes change as technology advances. In the past, dyes and pigments drove most demand, but growth increasingly comes from organic semiconductors, OLEDs, and flexible display research. Our pilot plant engineers constantly adapt their approach to match these shifts. We tailor particle size or moisture content to specific customer use cases based on what reliably enhances coupling yields or electronic performance. We publish updates to our specifications every year to highlight real-world performance trends, not just backward-looking purity numbers.

    We have invested in lab automation and in-house analytics so we can react faster to customer needs and regulatory developments. Our philosophy is that end-user innovation, in fields like polymer synthesis or solar energy, will only work if every building block they use is trusted—down to the level of bromine atom placement and contaminant avoidance. We constantly review literature and consult with science teams worldwide, keeping up to date with both established and emerging applications. Our willingness to adapt, update standards, and disclose non-confidential production details has led to partnerships with institutions and companies developing products a decade ahead of market entry.

    Commentary: Why Quality and Process Integration Matter

    From years on the shop floor and in customer QA meetings, we have seen that buying direct from a manufacturer brings advantages beyond cost savings. Transparency matters. When a university researcher picks up the phone to discuss an anomalous peak in their NMR or a stuck-flask scenario, only the actual producer can walk through every stage of the material’s lifecycle and suggest fixes that work. Our role is not just delivering molecules but supporting research timelines and commercial processes that depend on tight tolerances and reproducibility.

    Long-term relationships drive mutual understanding. Over the last decade, several of our early buyers have grown from startup labs to global formulators. Their staff now rely on our in-process control logs as much as our shipping labels, urging us to keep enhancing process reliability and documentation. Our trust-based model, rooted in regular feedback calls and sample exchange, flows directly from the firsthand lessons of troubleshooting hundreds of plant runs.

    From synthesis and purification to packaging and support, our perspective stays grounded: perfection comes not from luck or minimum compliance, but from commitment. Complex issues—unexpected reactivity, logistics hurdles, end-user customization—benefit from the frontline experience of those who actually run the reactors, not faceless intermediaries. For everyone at our plant, reliability, openness, and pride in the work mean more than just meeting written specifications. Our approach to manufacturing 2,7-dibromonaphthalene reflects that mindset.