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2,6-Dimethyl-3-Nitropyridine

    • Product Name 2,6-Dimethyl-3-Nitropyridine
    • Alias 2,6-Lutidine-3-nitro
    • Einecs 231-851-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    754916

    Chemical Name 2,6-Dimethyl-3-Nitropyridine
    Molecular Formula C7H8N2O2
    Molecular Weight 152.15 g/mol
    Cas Number 95559-25-2
    Appearance Yellow crystalline solid
    Boiling Point No data available
    Melting Point 72-74 °C
    Solubility Slightly soluble in water; soluble in organic solvents
    Density 1.24 g/cm3 (estimated)
    Flash Point No data available
    Iupac Name 2,6-dimethyl-3-nitropyridine
    Structure Pyridine ring with nitro group at position 3 and methyl groups at positions 2 and 6

    As an accredited 2,6-Dimethyl-3-Nitropyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 2,6-Dimethyl-3-Nitropyridine, sealed with a tamper-evident cap and labeled with hazard warnings.
    Shipping 2,6-Dimethyl-3-Nitropyridine is shipped in tightly sealed containers, protected from light, heat, moisture, and incompatible substances. The packaging complies with chemical safety regulations, featuring hazard labeling. During transport, it must be handled by trained personnel, ensuring the package remains upright and undamaged to prevent leaks or accidental exposure.
    Storage 2,6-Dimethyl-3-nitropyridine should be stored in a tightly sealed container, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers and reducing agents. Store in a cool, dry, well-ventilated area, preferably in a dedicated chemical storage cabinet. Properly label the container and ensure it is kept away from moisture and ignition sources. Always follow local chemical storage regulations.
    Application of 2,6-Dimethyl-3-Nitropyridine

    Applications of 2,6-Dimethyl-3-Nitropyridine in Industrial Manufacturing

    As an established producer of 2,6-Dimethyl-3-Nitropyridine, we supply this key intermediate to advanced manufacturers in sectors demanding consistent purity, regulatory compliance, and integration support. Our material is specified for use in well-defined downstream processes, contributing to the production of high-value specialty goods. Below, we detail the principal application scenarios supported by our material, based on documented industry practice and regulatory frameworks.

    1. Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis

    Customers in the pharmaceutical sector use 2,6-Dimethyl-3-Nitropyridine as a heterocyclic building block in the synthesis of certain Active Pharmaceutical Ingredients, especially for pyridine-derived molecules. This intermediate is favored for its reliability in constructing core scaffolds in antihypertensive and anti-inflammatory molecules. It enters the synthetic route during heterocycle assembly prior to final API formation, and all applications are subject to stringent pharmaceutical quality control.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practices for Active Pharmaceutical Ingredients
    • EU GMP Part II for APIs
    • Ph. Eur., JP, and USP reference monographs as applicable to downstream APIs
    • FDA 21 CFR 210/211 for pharmaceutical manufacturing

    Typical usage ratio

    • Usage ranges from 0.5% to 1.2% molar ratio, calculated based on the target API synthesis route and batch yield requirements. Adjustment is determined by the specific synthetic transformation and stoichiometric efficiency.

    Downstream process integration

    • Material introduction in the early heterocyclic ring formation step, followed by selective nitration or coupling; purification precedes further functionalization stages to ensure compliance with residual solvent and impurity profiles.

    Final product types

    • Active pharmaceutical ingredients in finished tablet or injectable forms, including proprietary antihypertensive agents and select immunomodulatory small molecules.

    2. Agrochemical Intermediate Manufacturing

    2,6-Dimethyl-3-Nitropyridine serves as a precursor in the production of active ingredients for crop protection formulations, including the synthesis of specialized pyridine-based herbicides and insecticides. The highly selective introduction of nitro and methyl groups supports targeted functionalization in multi-step agrochemical synthesis, in line with the regulatory scrutiny for environmental traceability in end-use applications.

    Industry compliance standards

    • ISO 9001:2015 for agrochemical manufacturing
    • FAO/WHO Specifications for Pesticides
    • Regulation (EC) No 1107/2009 (EU plant protection product regulation)
    • US EPA 40 CFR Part 158 (data requirements for pesticide chemicals)

    Typical usage ratio

    • Formulators add 2,6-Dimethyl-3-Nitropyridine at 0.7–1.8% molar basis, according to the specific synthesis protocol and desired yield for downstream active pesticide moieties.

    Downstream process integration

    • Material enters the manufacturing process during initial condensation or cyclization, followed by further substitution and coupling reactions; process controls ensure carryover of nitro functionality is minimized in finished actives.

    Final product types

    • Pyridine-derived herbicides, formulated insecticides, and selective pre-emergent crop protection agents.

    3. Dye and Pigment Intermediate Synthesis

    Manufacturers of specialty dyes and pigments employ 2,6-Dimethyl-3-Nitropyridine as an essential intermediate for achieving precise electronic and structural modulation in advanced colorants. Its controlled incorporation enables tailored chromophore assembly, especially in mordant and solvent dye preparations, in line with rigorous standards for colorfastness and purity demanded by textile and coatings industries.

    Industry compliance standards

    • OEKO-TEX Standard 100 (textile safety and chemical content)
    • ISO 9001:2015 for pigment and dye manufacture
    • REACH (EC No 1907/2006) registration for dye intermediates
    • ZDHC Manufacturing Restricted Substances List (MRSL) for textile chemicals

    Typical usage ratio

    • Adopted at concentrations between 1% and 2.5% by weight, depending on target tint strength and pigment route; dosage adjusted based on aimed chromophore extension and final solubility.

    Downstream process integration

    • Introduced at pigment backbone construction, where nitro group activation or methyl-directed condensation defines hue; followed by purification and standardization for reproducibility across batches.

    Final product types

    • Solvent dyes, metal-complex dyes, high-purity textile colorants, performance pigments for plastics and coatings.

    4. Specialty Electronic Material Synthesis

    In advanced electronics manufacturing, 2,6-Dimethyl-3-Nitropyridine forms part of the building blocks for organic semiconductors and emissive-layer materials in OLED displays and specialty sensors. Its selective methyl and nitro substitution patterns foster controlled electron transport in the polymer backbone, facilitating precision in custom device engineering.

    Industry compliance standards

    • ISO 14001 for environmental management in electronics production
    • RoHS Directive 2011/65/EU for hazardous substances in electrical and electronic equipment
    • IECQ QC 080000 HSPM:2005 for hazardous substance process management in electronics

    Typical usage ratio

    • Integrated at 0.3–0.8 molar equivalents in precursor assembly, depending on chain extension requirements and device architecture. Ratio tailored based on desired bandgap and photoluminescence performance.

    Downstream process integration

    • Blended with additional monomers or co-reactants during the pre-polymerization or pre-oxidation step; followed by casting, doping, or thin-film deposition for functional device construction.

    Final product types

    • Organic light-emitting diode (OLED) layers, flexible printed circuit components, specialty photodetectors, charge-transport polymers for advanced electronics.
    Free Quote

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    Certification & Compliance
    More Introduction

    2,6-Dimethyl-3-Nitropyridine: Behind the Product

    A Manufacturer’s Perspective on Value, Process, and Use

    Producing 2,6-dimethyl-3-nitropyridine is a blend of precision and commitment. Manufacturing this specialty nitropyridine compound takes both chemical experience and the right technical setup. Our team draws on years of fine chemical production experience, optimizing each batch to meet strict standards. This compound plays a significant role in pharmaceutical intermediates and crop protection research, and its reliable performance keeps chemists coming back for more.

    The Product at a Glance

    We focus on practical quality rather than marketing terms, and every batch of our 2,6-dimethyl-3-nitropyridine reflects that. The compound’s structure, built around the pyridine ring, features methyl groups at the 2 and 6 positions and a nitro group at position 3. It usually comes as a light yellow solid and shows good shelf stability when stored in well-sealed containers away from moisture and direct light.

    Our regular output sticks closely to purity figures exceeding 98% by GC. We see little variance because our reactors give neat temperature control and solid mixing, and our purification line removes stubborn by-products efficiently. Measured melting point range falls between 67-71°C. We always analyze each lot using NMR and GC-MS, and our packing process keeps contamination at bay.

    Real-World Applications

    Why do chemists ask for this particular nitropyridine? Its electronic properties make it valuable as a starting point for assembling more complex nitrogen heterocycles. In active pharmaceutical ingredient (API) research, 2,6-dimethyl-3-nitropyridine is more than a lab oddity. Researchers use it for preparing key intermediates, particularly those that require selectivity in further substitution or reduction on the ring.

    It also crops up in organic electronics, dyes, and fine chemicals work. The electron-withdrawing nitro group and the methyl substituents combine to give a distinct reactivity profile that’s hard to match. We frequently see requests from both university labs and industrial development teams. Sometimes, the compound acts as a scaffold for patented lead molecules. Anyone looking to introduce specific functional groups in a controlled way appreciates the flexibility of this molecule.

    Crop science teams have turned to 2,6-dimethyl-3-nitropyridine in synthetic pathways when developing new fungicides and herbicides. Selectivity during synthesis becomes easier with this pattern of substitution, and consistent supply helps researchers scale their efforts with confidence.

    Process Choices and Consistency

    Our operation leans on careful raw material sourcing and rigorous process monitoring. The keys to reliable 2,6-dimethyl-3-nitropyridine production lie in the oxidation and nitration steps. Controlling exothermic reactions and minimizing trace by-product formation requires both hands-on skill and data-driven control. Batch records keep us honest, and our operators know every hint of color or odor means something about purity.

    We install safety interlocks, run trial batches with in-process testing, and focus on solvent recovery. Green chemistry isn’t just a slogan for us. For example, our team worked for months to move away from older nitrate sources to new alternatives that cut down on secondary waste. Customers notice the difference in the clarity and purity of the powder. These process changes also reduced hazardous waste output by nearly a third last year, lowering both environmental impact and disposal costs for everyone involved.

    Why Not Another Pyridine?

    2,6-dimethyl-3-nitropyridine stands out when compared to related compounds. Compared with 3-nitropyridine, for example, the dimethyl groups increase selectivity in the ring reactivity, helping downstream chemists avoid side reactions that often crop up in unsymmetrical N-oxidations or reductive functionalizations.

    We get plenty of inquiries asking whether other substituted nitropyridines could replace this compound. Chemically, the distribution of electron density here is unique, letting the nitro group remain stable while providing anchor points for further synthetic work. Our customers who tried single-methyl or unsubstituted nitropyridines saw higher rates of off-target reactions and often lower yields. It’s not just about making something similar; it’s about keeping hard-won reliability in your research or production process.

    Process-wise, our product’s consistency means less time spent on purification and analytics for those using it downstream. Saving a few hours of column time or avoiding a tricky crystallization means real cost savings, especially at multi-kilo scale.

    Shipping and Storage Considerations

    Chemicals such as this shouldn’t be handled on autopilot. Our packing options include tightly sealed bottles in dry packaging, ensuring that moisture and air stay out until the last crystal is transferred. Years of experience have taught us that common mistakes—storing the compound in high humidity or near direct sunlight—will shorten shelf life. Even the choice of liner in the drum can make a difference.

    Stability over time comes down to tight control of residual volatiles and an inert environment. Generics and lower-purity material often run into issues with trace decomposition, leaving end users with unexpected impurities that complicate further synthesis. We monitor all outgoing shipments for compliance with labelling and sealing, keeping the concentration and quality intact from our factory to your workspace.

    Supporting Responsible Use

    Handling nitroaromatic compounds calls for care. From our experience, lab staff who keep up with best practices avoid the headaches that can come with organic nitrates. We provide clear information about proper storage and safe handling because, regardless of customer experience level, it lowers the chance of mishaps.

    We source our starting materials from reputable suppliers and insist every shipment passes full traceability checks. You won’t see our staff taking shortcuts with paperwork or skipping routine safety checks. Our team communicates with customers about proper disposal routes for off-spec batches and unused material. No one benefits from cutting corners, and sharing this information helps build trust across the chemical industry.

    Beyond Purity: Why Consistency Matters

    It’s easy to obsess over purity figures. In practice, the reproducibility of every shipment trumps a few tenths of a percent here or there. We run validation tests to ensure that not only the main peak in the chromatogram matches expectations, but the profile of minor by-products stays under tight control.

    Some academic labs have shared their results with us, grateful that repeated batches from our line let them publish with confidence. For contract development groups, hiccups in reagent quality can mean delayed timelines and missed commercial targets. We know that pharmaceutical projects—especially those involving regulatory filings—depend on batch-to-batch reproducibility all the way to kilo scales.

    Our approach is to stay in close contact with customers through regular feedback and shared data. If a new analytical method better defines an impurity profile, we’re quick to adapt. Learning from customer needs makes our plant run more efficiently and bolsters your results in the lab.

    Sustainability in Practice

    The industry has changed. Sustainability is no longer a minor factor. We switched portions of our solvent system to recyclable alternatives that allow for closed-loop feedback on our emissions. Fume extraction and solvent recycling in our process area means fewer volatile organic emissions escape. In many cases, these choices cut our overhead costs, even while raising initial equipment investments.

    We work with local regulators and third-party auditors, reviewing safety and environmental records every quarter. Our in-house lab tracks wastewater profiles to avoid nitrate and organic load beyond legal discharge. Partnerships with licensed waste processors close the loop, and we document every kilogram.

    For customers who face their own sustainability requirements, our documentation helps support compliance and reporting. Down-the-line users benefit from traceability and minimized environmental impact.

    Your Colleagues’ Experience Informs Our Improvements

    Direct feedback from scientists using our 2,6-dimethyl-3-nitropyridine tells us what matters most. One pharmaceutical researcher reported better selectivity in a cross-coupling route versus single-methyl analogues. A synth chemist in agro-tech commented on lower work-up times, attributing it to cleaner product arrival every order. Our technical support channels are always open, with staff ready to troubleshoot, discuss analytical details, and share best practices for both process and lab work.

    Supporting research beyond mere supply means sharing insights on reaction scale-up, expected impurities, or recommended crystallization solvents. We don’t expect buyers just to order and hope for the best; collaboration matters in every step. Regular dialogues with users often steer our next process improvement or product enhancement.

    Future Outlook: Technology, Quality, and Service

    Our mission stays rooted in straightforward, practical chemistry. Plant upgrades, tighter in-process controls, and new purification technology aren’t just hollow investments but responses to real-world demands from industry, academia, and R&D clients.

    We avoid shortcuts and keep our team trained on newer safety, quality, and sustainability practices. Customers rely on us to keep their supply chain robust and trouble-free. The future for 2,6-dimethyl-3-nitropyridine revolves around collaboration, transparent communication, and honest production. As science advances, the expectations for quality and traceability will only grow—something our company is ready to deliver.

    Choosing the Right Supplier Matters

    Many research setbacks come from inconsistent chemical quality. We know chemists don’t have the time or budget to babysit reagents, so our experience gives peace of mind. Our plant staff takes hands-on responsibility at each production stage, from charging reactors to packing the final product.

    Learning from years of chemical manufacturing, we know the bottlenecks that can slow project progress. Our teams address these before they reach the customer. We invest in analytical instrumentation, maintain careful cleaning protocols, and document every processing step.

    Partners return to us for future batches because reliability and transparency make a real difference. From scale-up support to post-sale technical advice, we see our role as extending beyond supplier—becoming a true collaborator in your lab’s success.

    Concluding Thoughts: Manufacturing with Purpose

    Producing and supplying 2,6-dimethyl-3-nitropyridine goes beyond making a specification. It requires skill, care, and open lines to those doing important work, whether in the lab or on the production floor. By investing in the right process controls, caring for our people, and keeping sustainability central, our company aims to set a standard—not just in quality, but in partnership and responsible stewardship of chemistry for the future.