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2,6-Dichlorothiobenzamide

    • Product Name 2,6-Dichlorothiobenzamide
    • Alias Chlomethiazole
    • Einecs 221-152-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    124951

    Chemical Name 2,6-Dichlorothiobenzamide
    Cas Number 97-18-7
    Molecular Formula C7H5Cl2NS
    Molecular Weight 206.09 g/mol
    Appearance White to off-white solid
    Melting Point 152-154°C
    Boiling Point 361.4°C at 760 mmHg
    Solubility Slightly soluble in water
    Purity Typically ≥98%
    Storage Conditions Store in a cool, dry place and keep container tightly closed
    Synonyms Dichlobenil, DCBN, CAS 97-18-7
    Density 1.52 g/cm³
    Inchi Key QSAGJNSIOWHRRY-UHFFFAOYSA-N

    As an accredited 2,6-Dichlorothiobenzamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2,6-Dichlorothiobenzamide is supplied in a sealed amber glass bottle with hazard labeling and detailed safety instructions.
    Shipping 2,6-Dichlorothiobenzamide is shipped in tightly sealed containers to prevent leakage and contamination. It is typically stored and transported at room temperature, away from incompatible substances. Packaging conforms to regulatory requirements for hazardous chemicals, with clear labeling indicating its identity and any associated hazards. Handle with appropriate safety precautions during transport.
    Storage 2,6-Dichlorothiobenzamide should be stored in a cool, dry, and well-ventilated area, kept tightly sealed in a chemical-resistant container. Protect it from light, moisture, heat, and incompatible substances such as strong oxidizers. Clearly label the storage container and keep it away from food and drink. Ensure access is restricted to trained personnel, following standard chemical safety procedures.
    Application of 2,6-Dichlorothiobenzamide

    Applications of 2,6-Dichlorothiobenzamide in Industrial Manufacturing

    2,6-Dichlorothiobenzamide supports a variety of specialized industrial processes. As a direct manufacturer, we supply this intermediate for established sectors with controlled manufacturing and stringent compliance requirements. Below we detail major application fields, technical integration, compliance obligations, formulation ratios, and typical final products.

    1. Herbicidal Intermediate for Acetanilide Herbicide Synthesis

    This material plays a key role as a building block in the synthesis of several chloroacetamide-type herbicides, including metolachlor and related actives. Agrochemical manufacturers utilize it during key thioamide functionalization steps. Controlled addition rates and purification methods govern its integration for batch-to-batch QC reliability in herbicide active ingredient output. Its use falls under tight regulatory monitoring for both environmental and operator exposure.

    Industry compliance standards

    • FAO/WHO Specifications for Agricultural Pesticides
    • ISO 9001:2015 – Quality management for agrochemical intermediates
    • REACH (EC) No 1907/2006 compliance for raw material handling
    • OECD Good Laboratory Practice for synthesis verification

    Typical usage ratio

    • Generally 0.95–1.15 molar equivalent per target active compound, adjusted based on exact yield and side reaction control.

    Downstream process integration

    • Entry during core intermediate coupling or condensation reaction stage, with strict temperature and solvent control.
    • Followed by separation, purification, and conversion to finished herbicide actives.

    Final product types

    • Active metolachlor (selective pre-emergence herbicide)
    • Dimethenamid
    • Alachlor
    • Formulated crop protection blends for maize, bean, and sunflower farming

    2. Synthesis Intermediate for Sulfur-Containing Pharmaceuticals

    Producers of active pharmaceutical ingredients (APIs) with thioamide and related moieties use this compound in multi-step syntheses, particularly for organosulfur drugs. The integration focuses on maintaining high purity and low residuals, as per ICH and pharmacopoeia requirements. Process chemists target precise addition points to ensure selective conversion, aided by staged addition and solvent washing to minimize impurities.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • Current USP / EP monographs for relevant APIs
    • GMP pharmaceutical production requirements
    • 21 CFR Part 210/211 (FDA controls for Drug Products)

    Typical usage ratio

    • 0.85–1.05 molar equivalent, adjusted based on API synthetic scheme and control of downstream impurity profiles.

    Downstream process integration

    • Used as a key sulfur source during core stepwise transformation, often at intermediate condensation or sulfurization stages.
    • Introduced in anhydrous or controlled moisture systems, immediately followed by reaction work-up under GMP conditions.

    Final product types

    • Thioamide-based pharmaceutical intermediates
    • Organosulfur drug substances (e.g., certain thioamide anti-thyroid agents)
    • Custom fine chemicals for medicinal chemistry programs
    • Clinical-grade pharmaceutical APIs

    3. Intermediate for Dyes and Specialty Pigments

    Chemical manufacturers in the colorants sector utilize this compound for synthesizing specific sulfur-bridged azo and thio-indigoid dyes. Its careful incorporation into colorant precursor streams delivers enhanced tinctorial strength and chemical stability. Application-specific QC verifies that batch purity and spectral characteristics meet strict dye industry benchmarks.

    Industry compliance standards

    • GMP/GLP protocols for specialty chemical synthesis
    • OEKO-TEX® Standard 100 for textile applicable colorants
    • EN 71-3 (Safety of Toy Dyes, migration of certain elements)
    • ISO 9001:2015 for dye and pigment manufacture

    Typical usage ratio

    • 0.9–1.2 molar ratio per dye precursor, with fine-tuning based on extinction coefficient and required pigment loadings.

    Downstream process integration

    • Charged into primary dye precursor synthesis step, enabling controlled sulfur incorporation before cyclization or azo coupling.
    • Subsequent color fixing and filter-press dewatering for pigment isolation.

    Final product types

    • Thio-functional azo dyes for cotton fiber
    • Specialty pigments for plastics and coatings
    • High-performance inks for industrial marking
    • Color masterbatches for polymer applications

    4. Chemical Intermediate in Rubber Processing Additives

    In the rubber chemicals industry, this compound serves in the synthesis of thioamide-based accelerators and anti-scorch agents. It ensures uniform curing kinetics and improved extrusion characteristics in downstream rubber compound manufacturing. Production teams dose the chemical under inert conditions, monitoring conversion rates and byproduct profiles relevant to vulcanization performance.

    Industry compliance standards

    • ISO 9001:2015 for rubber additives production
    • ASTM D4678 – Standard Practice for Rubber Compounding Materials
    • EU REACH Regulation for worker safety and raw material safety data
    • Factory Mutual quality risk management for chemical processing plants

    Typical usage ratio

    • Added at 0.5–2.0% of the total curing system, precise dose determined by rubber polymer type and accelerator blend.

    Downstream process integration

    • Formulation into masterbatches at the pre-mix phase, before main compounding and addition of peroxides or sulfur sources.
    • Monitored with in-process analytical methods to verify accelerator distribution.

    Final product types

    • Thioamide rubber accelerators
    • Anti-scorch additives for automotive and conveyor belt applications
    • Rubber hose and seal compound ingredients
    • Technical elastomer goods for industrial use
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    Certification & Compliance
    More Introduction

    Introducing 2,6-Dichlorothiobenzamide: Built on Decades of Chemical Manufacturing Experience

    Rooted in Practical Know-How

    Working at the intersection of chemistry and industry, we have spent years refining the production of 2,6-Dichlorothiobenzamide for reliability, consistency, and purity. In the world of substituted thiobenzamides, the 2,6-dichloro substituted variant holds special value due to its distinctive reactivity and performance profiles. Each batch, produced under strictly controlled conditions, demonstrates high standard consistency. Unlike off-the-shelf commodities, 2,6-Dichlorothiobenzamide evolves from experience-based process improvements and hands-on testing at the manufacturing floor.

    Model & Specifications: Bringing Chemical Precision to the Table

    Chemical manufacturing presents unique challenges when handling materials like 2,6-Dichlorothiobenzamide. Chemical purity, crystalline structure, moisture levels, and particle sizing must work together to meet advanced application demands. Our standard product, produced at high-purity grades, supports a range of technical requirements. With regular HPLC and GC analysis, lots achieve purity levels upwards of 99%. Particle sizing is controlled as part of the synthesis and final isolation process, targeting flowability and dispersion for easy handling in industrial environments. Over years of refining production, we have significantly reduced trace contaminants—including unwanted isomers—minimized batch-to-batch color deviations, and achieved odor consistency. Testing directly inside our facility, not through third parties, gives users the confidence of traceable quality from the source.

    Understanding What Sets 2,6-Dichlorothiobenzamide Apart

    Many chemical buyers ask about the functional strengths of 2,6-Dichlorothiobenzamide compared to generic thiobenzamides or other chlorinated analogues. In the early days, thiobenzamide itself was produced for fairly broad use. The introduction of the two chlorine atoms at positions 2 and 6 on the benzene ring changes the reactivity and stability of the molecule. This substitution pattern influences solubility, thermal profile, and partitioning in complex formulations. Using this knowledge, we tailored our synthesis route to avoid side-products from incomplete chlorination or byproduct formation common in less controlled operations.
    Key differences show up in real-world applications. In agrochemicals, for example, 2,6-Dichlorothiobenzamide displays markedly improved hydrolytic stability in typical formulation pH ranges, helping formulators design longer-lasting products. This compound’s higher resistance to oxidative degradation allows longer shelf life, especially under storage conditions prone to temperature fluctuations. Using in-house pilot lines, we have compared it side-by-side with single-chlorine or non-chlorinated thiobenzamide, measuring decomposition and color shift over time—a big concern for users needing batch-to-batch repeatability.

    Building Trust Through Transparency: Specification Tracing and Batch Control

    Our facility employs full-process batch tracing, meaning each production lot pairs to a full analytical record. We don’t rely on post-production testing alone; we use in-line monitoring and have specialized operators trained to identify subtle changes in slurry consistency and crystal habit during isolation. The plant laboratory cross-verifies each stage of synthesis, not just the end product. We invite partners periodically for technical audits, offering open access to production logs and closed samples from ongoing lots. This transparency builds trust for technical and procurement teams.

    Application Knowledge: In the Field and The Lab

    Having supplied numerous formulation chemists and R&D teams, we’ve seen how different applications ask different questions about a molecule. One year, a water treatment chemist reviewed our certificate of analysis and flagged the trace appearance of mono-chlorinated derivative. We worked directly with process engineers to isolate the problem in the chlorination step, fine-tuned reaction temperatures, and virtually eliminated the impurity in the next production cycle. These ongoing feedback loops sharpen our ability to produce a product adaptable for high-purity technical, laboratory, or production-scale needs.

    Downstream, 2,6-Dichlorothiobenzamide is regularly evaluated for surface activity, reactivity with natural and synthetic fibers, and resistance to biological breakdown. These features have positioned our product as a dependable component in crop protection, dyes intermediates, and certain specialty polymer workflows. In real-world feedback, formulators have noted less batch-related haze and no unintentional color shift when switching to our supply compared to imported alternatives.

    Safety and Handling Reality: Manufacturing Perspective

    Chemists working the production line understand the importance of vigilance during crystallization and drying steps, where dust control and personal protection become vital. Our team implements strict air monitoring, local exhaust, and regular surface residue checks in all work zones. At scale, raw material quality and liquid phase monitoring serve as the first line in ensuring controlled, consistent yield and minimizing unplanned releases. Workers undergo annual safety recertification, including real-world response drills to product spills or material handling incidents. We make this commitment because handling chlorinated intermediates responsibly safeguards both our workers and downstream customers.

    Continuous Improvement in the Manufacturing Pipeline

    A chemical plant never stands still. Our process development group monitors every key metric from raw input quality to crystallization yield and effluent composition. Several years ago, our operation initiated a phased shift to semi-batch reactor operation for the chlorination step, which reduced cycle times and improved selectivity. This directly cut down the fraction of off-spec product routed to waste. Automation modules now help record real-time temperatures, agitation rates, and reagent dosing profiles, letting foremen optimize each run with higher precision.
    We listen closely to end users’ feedback. If a formulator in the dye industry reports trace-level color contamination that creates quality challenges downstream, we trace the issue to minor solvent carryover and introduce an extra filtration step. When one segment of water treatment users raised concerns about odorous byproducts, we adjusted condensation temperatures and achieved a more neutral aroma profile, which created immediate downstream blending benefits.

    Regulatory Awareness: Meeting Demands Beyond The Lab

    Regulatory requirements only grow more complex each year. Our compliance team works with operators to ensure full documentation, SDS updates, and data transparency for each supply region. Batch-specific analytical profiles are supplied directly with product shipments, supporting downstream needs for regulatory reporting or process qualification. All production steps, from raw acquisition to final packaging, comply with regularly audited protocols for chemical, worker, and community safety. Auditors regularly inspect the plant, and we have welcomed both external and customer-led reviews.
    This experience means we understand not just the chemistry but the practical realities of moving regulated chemicals into downstream sectors—helping clients document and trace product as required through third-party audits or customer-initiated inspections.

    Application Insights: Where 2,6-Dichlorothiobenzamide Succeeds, and Where It Faces Limits

    We see 2,6-Dichlorothiobenzamide in diverse sectors, but two of the most impactful fields have proven to be dyes and crop protection. In the dye sector, its reactivity enables high-color-density intermediates. Its selectivity during chromophore building allows color shading rarely accessible with other isomers. Technical teams prefer it in certain synthesis routes due to the manageable profile of byproducts and the tuning of physical properties. On the agricultural side, the hydrolytic and photostability of the product meet the durability standards needed for today’s sophisticated formulations. Formulators can fine-tune active release while maintaining shelf stability, making it possible to create crop treatments lasting through unpredictable weather cycles.
    Some limitations exist. In certain surface modification workflows or highly aqueous blends, even this compound’s improved resistance to hydrolysis does not guarantee indefinite stability, especially if pH conditions slip outside neutral. Our plant team provides direct consultation to partners needing to troubleshoot or optimize their formulation recipes, focusing on blending protocols or pre-mix steps that maximize stability and function.

    Quality You Can Hear, See, and Measure

    What does quality really look like, apart from numbers on a report? Our plant supervisors start each production run by visually inspecting crystal initiation and associating tiny habit changes with earlier deviations in moisture control. In the finishing area, operators listen for slight changes in dryer acoustics that have previously indicated fan blockages—helping to preempt dust problems before they occur. We run “smell checks” at set intervals, using the unique aromatic profile of 2,6-Dichlorothiobenzamide as a first clue to process stability. Spectroscopic verification and purity tally up on paper, but the on-the-floor experience heightens confidence.

    Downtime and waste reduction aren’t possible without these details. By linking hands-on plant knowledge with advanced automated monitoring, we deliver a 2,6-Dichlorothiobenzamide batch that downstream partners can trust for both consistency and reactivity, supporting everything from laboratory-scale tests to multi-ton production runs.

    Supply Reliability: Adapting to an Unpredictable Market

    Chemical markets shift overnight. We have weathered disruptions—raw material fluctuations, transport delays, even sudden surges in demand. By building redundancy into our raw materials pipeline and investing in on-site supply chain management, we buffer unpredictable external shocks. Strategic technical partnerships with logistics providers further enhance delivery consistency, even into locations with strict customs controls. We store safety stocks where possible and keep close communication channels open with long-term partners to give early notice on any supply changes.

    Our experience shows that even minor disruptions in supply ripple downstream, raising costs and reducing confidence. We encourage ongoing schedule-sharing and periodic planning calls with buyers, so any potential bottlenecks can be resolved quickly, either by rerouting inventory or running emergency campaigns if needed. This hands-on approach, honed through years of industry change, distinguishes our service as more than just chemical dispatch—it’s a genuine relationship built for resilience.

    Environmental Commitment: Real Actions, Not Talk

    Environmental responsibility in manufacturing doesn’t arise from compliance alone. Over time, our technical team has designed wastewater recycling units and installed upgraded air-scrubbing systems in response to evolving local regulations. Continuous improvements in reaction yield and recycling lead directly to less effluent, smaller energy footprints, and reduced raw material demand. Operating efficiency benefits both our business and the surrounding community.
    We have taken on green chemistry research to reduce dependence on certain chlorinating agents, mitigate on-site solvent usage, and recover more process heat for building utilities. Progress doesn’t arrive overnight, but incremental steps lead to impact. We are proud when site audits find measurable reduction in chemical runoff or improvement in energy intensity per ton shipped—actual data, not aspirational goals.

    What Working With an Actual Manufacturer Means for the End User

    Choosing 2,6-Dichlorothiobenzamide sourced directly from a manufacturer brings practical benefits unavailable from brokers or distant resellers. Direct communication with operators and technical teams sharply reduces ambiguity and speeds up problem resolution. Any concerns—whether they relate to color, odor, or integration into your process—filter quickly to individuals who understand the production chemistry, not intermediaries unfamiliar with physical realities or supply logistics.

    We carry insights based on real batches, not theoretical calculations or datasheet compilations. Whether supporting large-volume procurement or specialized applications with unique purity or sizing, we back every shipment with transparent documentation and willingness to provide technical consultation.
    This partnership means less risk during troubleshooting and more support for your internal development timelines. Many buyers send technical teams to visit our facility, gaining an understanding of our process—from raw input to final QC signoff. Open dialogue around actual limitations and realistic solutions creates a shared trust you won’t find in a purely transactional marketplace.

    Real-World Feedback Shapes Tomorrow’s Product

    Ongoing feedback reshapes both our product and plant every year. We have adapted purification and packaging steps based on what is actually seen in partner R&D trials. For example, batch packaging processes evolved after formulators flagged caking concerns in humid climates. We switched to alternate packaging and added in-line desiccant pulses, providing measurable improvement in end-use ease. We have responded to evolving end-application requirements in dye, fiber, crop protection, and specialty chemical formulations, incorporating lessons learned to reduce handling difficulties or incompatibility with certain excipients or carriers.

    We encourage direct feedback and regularly organize knowledge-sharing sessions with customers and academic partners. Each interaction generates ideas for continued improvement—whether in reactivity, shelf-life, batch presentation, or overall sustainability of our operations. We do not rest on past achievements, but push every season for measurable improvements based on actual user experience.

    Looking Ahead: Role of 2,6-Dichlorothiobenzamide in a Changing Industry

    High-purity, well-characterized 2,6-Dichlorothiobenzamide will remain a go-to building block for innovation in colorants, crop protection agents, and more. As regulatory expectations rise and performance pressure increases, having a direct manufacturing partner focused on continuous improvement and process transparency grows in importance. Our team remains on the plant floor, in the lab, and in technical meetings with partners—ready to adapt, share knowledge, and support every practical demand that comes with real-world chemical manufacturing.