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HS Code |
958895 |
| Chemicalname | 2,6-Dichlorobenzylamine |
| Casnumber | 4437-22-3 |
| Molecularformula | C7H7Cl2N |
| Molecularweight | 176.05 g/mol |
| Appearance | White to off-white crystalline solid |
| Boilingpoint | 287-289 °C |
| Meltingpoint | 61-65 °C |
| Solubility | Slightly soluble in water; soluble in organic solvents |
| Density | 1.33 g/cm³ |
| Purity | Typically ≥98% |
| Synonyms | 2,6-Dichlorobenzenemethanamine |
| Smiles | C1=C(C(=CC=C1Cl)Cl)CN |
| Inchi | InChI=1S/C7H7Cl2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H,4,10H2 |
As an accredited 2,6-Dichlorobenzylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 2,6-Dichlorobenzylamine, tightly sealed, labeled with hazard warnings and product details. |
| Shipping | 2,6-Dichlorobenzylamine is shipped in tightly sealed, chemical-resistant containers to prevent leaks and contamination. It is handled as a hazardous material, complying with relevant regulations such as DOT and IATA. The shipment should be clearly labeled, protected from physical damage, and kept away from incompatible substances during transport. |
| Storage | 2,6-Dichlorobenzylamine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers and acids. Protect it from moisture and direct sunlight. Clearly label the container, and ensure all personnel handling the chemical are equipped with appropriate personal protective equipment. |
Applications of 2,6-Dichlorobenzylamine in Industrial ManufacturingAs the original manufacturer, we provide 2,6-Dichlorobenzylamine for downstream partners who require strict consistency, traceability, and commitment to the highest regulatory and technical standards in advanced industrial applications. The following sections detail real, verified end-use integration segments where this intermediate supports precise formulation, controlled reactivity, and efficient process economics as demanded by established markets. 1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) SynthesisPharmaceutical manufacturing enterprises employ this raw material in the synthesis of select active pharmaceutical ingredients, especially in processes where dichloro substitution patterns influence pharmacological properties. Its introduction at the key step enables the formation of aromatic amine moieties integral to finished APIs. Utilization depends on batch-specific product requirements, tailored for multi-step organic synthesis with downstream purification. Production is monitored under validated protocols aligned with global medicinal chemistry standards. Industry compliance standards
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2. Agricultural Chemical Synthesis (Herbicide and Fungicide Intermediates)Leading crop protection manufacturers rely on this amine to construct key intermediates in triazole, imidazole, and other agroactive molecule classes. Its dichlorinated scaffold enhances bioactivity and environmental stability, and it is introduced early in the synthetic route to maximize downstream processing efficiencies. Integration is specifically aligned with regulated compound lists and government-mandated purity controls in the agchem sector. Industry compliance standards
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3. Specialty Polymer and Resin ModificationProducers of performance polymers and specialty coatings employ this dichlorinated aromatic amine to impart unique thermal and chemical resistance characteristics to advanced resins. It is usually used as a chain terminator or reactive modifier in polymer synthesis, responding to demand for high-performance composites in electronics and engineered structures. Processing control and accurate dosing are critical to achieving specified mechanical and dielectric properties required by end-users. Industry compliance standards
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4. Textile Chemical Intermediates (Colorant and Auxiliary Synthesis)Major textile auxiliaries and dye manufacturers utilize the dichlorinated amine group to build molecules that deliver specific fastness, brightness, and fabric compatibility attributes. The compound’s reactivity supports the formation of cationic dye intermediates and raw materials for fiber-level finishing aids. Integration is carefully adjusted based on fiber type and regulatory safety data of the final additive. Industry compliance standards
Typical usage ratio
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In the world of intermediate chemicals, few compounds prove as versatile as 2,6-Dichlorobenzylamine. Inside our production floors, our team brings decades of hands-on experience transforming precursors into this amine, built on robust process controls. It’s not a commodity we ship off without thought. We put real focus on consistency, batch-after-batch, because quality at this stage eventually decides how downstream syntheses perform. Direct from the manufacturer, the story of this compound stretches from concept to lab scale, to full-scale manufacturing integrations where purity, moisture content, and byproduct profile factor into every customer feedback loop.
Every producer faces the same chemistry: a benzene ring, two chlorine groups, an amine. What sets apart our 2,6-Dichlorobenzylamine is diligence through every process step—starting with source materials, carried through distillation and careful packaging, checked again by a team that’s spent years understanding what “clean” product should look and smell like. On specification, we’re talking a physically stable, white-to-off-white solid, with melting points and loss-on-drying numbers that confirm the absence of unwanted hydration or degradation. HPLC and GC regularly back up our word, because partners in pharmaceuticals, agrochemicals, and colorants run their own checks, and reputations ride on those lab results.
Cutting corners on raw material selection or running hot on reaction parameters can show up where it hurts—impurities that spoil yields, unpredictable cropping in crystallization, downstream filtration headaches. We battle through those details every week, measuring and adjusting until each batch falls into the expected analytical windows. The cascade of batch records, in-process controls, and archived chromatograms isn’t about paperwork; it’s about hard lessons learned from years of troubleshooting.
Talking uses means thinking about the end user’s process, not just the next sale. In our own experience, demand for this amine mostly circles back to three sectors. For active pharmaceutical ingredients, 2,6-Dichlorobenzylamine often acts as a building block on custom syntheses. Its amine functionality opens pathways for condensation, acylation, or ring closure steps. The dual chloro groups give selectivity—one ortho to the amine providing reactivity control that you simply don’t get from para- or meta-chloro isomers.
Manufacturers of herbicides and insecticides rely on this compound for similar reasons. Downtime in an agchem plant costs big, so they ask pointed questions about we produce, store, and transport this intermediate. Our QC teams work closely with formulators who use the 2,6-dichloro substitution to fine-tune bioactivity in target molecules—because the difference between a potent active and a failed batch might rest on a trace of residual moisture, a ppm of organosulfur contamination, or subtle batch-to-batch color variation.
Dye and pigment specialists prefer this molecule as it creates symmetry and electron push-pull that make for sharp, vibrant hues. Here, clean amine groups matter for dye coupling reactions. A yellow cast or off-smell points straight back to upstream issues—something our technical managers have learned to spot by eye and nose, backed up with TLC plates and colorimetric titrations before signing off on shipments.
Many outsiders look at a drum or polybag and see a commodity. Our engineers see past the packaging. Each packout is the end result of weeks wrangling supply chain raw materials, tuning reactor pressure, and working through salt removal in post-synthesis. Throttling scale from pilot runs to kilo lots never comes clean on the first try. At shifts’ end, our chemists and operators gather to walk through what worked and what threw curveballs—maybe a new grade of chlorobenzyl chloride brought higher ionic loads, maybe a tweak to water rinse cycles reduced sodium drift.
No two batches behave exactly the same; some years, we get quieter lots, other years introductions of new tank materials or utility water upgrades show up as changed impurity fingerprints. Only by keeping flush logs, routine lab analysis, and direct communication with our packaging staff have we kept end-users insulated from these bumps. Open feedback from formulators—whether for a poorly flowing powder or a higher-than-expected moisture reading—is not a complaint to us, it is a guide. We reflect on several adjustments and corrective actions based closely on user data, not protocols made by committee in a distant office.
Requests sometimes come in asking about possible swaps—could meta- or para-dichlorobenzylamines work the same? After years of technical dialogue, the reality is nobody trusts a switch blindly. Substitution triggers regulatory reviews, revalidation, and process retuning. Technical properties diverge: The ortho arrangement (2,6-) pins down reactivity in ways that remain unique. Neighboring substitution often boosts steric hindrance, shaping selectivity in coupling steps—critical for both medicinal chemists looking to avoid off-target interactions and agrichemists who fine-tune field performance.
We’ve run small-lot experiments for partners willing to trial changes. In every case, higher costs and lower yields prompt returns to the tried-and-true 2,6-isomer. Whether in aniline derivatives or advanced intermediates, the performance difference gets magnified when production scales up from grams to tons. Sluggish reactions, color changes, or unpredictable side products appear, translating to greater waste and missed deadlines. These are lessons learned hands-on—not from a desk, but from real-world pilots, supported by reference samples and retained lot archives.
Over the past two decades, regulatory standards have evolved fast. Partners in pharma or crop protection face ever-tighter controls on trace metals, residual solvents, and potential genotoxins. As a dedicated manufacturer, we have invested heavily in traceability and documented cleaning regimes. Every shift logs solvent cycle times, filter changeouts, and micron ratings, with every drum labeled with trace coding back to batch operator, receiving date, and relevant analytical signoff.
When regulatory reviews send questions months after delivery, our staff can walk right back through soak tests and batch journals—because rechecking is not about compliance, it’s about saving hours for clients facing a delayed release or retest request. In-house records are more than data points; they’re insurance against costly delays, built on routines honed by operator experience and customer pushback.
Clients who buy through distributors rarely see this level of transparency; traders buy low and sell high without tracking lot-level changes. As the originating producer, our real burden and our advantage comes through in the paperwork: chromatograms that match lot number and delivery, impurity profiles for each campaign, and in-person signoff on cleaning and vessel inspection. That’s not paperwork for a shelf—it’s daily work to support customer launches, regulatory filings, and internal troubleshooting.
Market pressure sometimes drives a race to the bottom on cost. Our operators know the real risks: off-brand batches bought at auction, or mishandled inventory, don’t always show red flags at receipt. Later, under the right reaction or catalyst, off-grade 2,6-Dichlorobenzylamine causes failed reactions, stuck columns, or even shutdowns. We stick to high-purity standards in mainline runs, using clean inert atmospheres and closed transfer to reduce the risk from oxidation or trace acids.
Some of our oldest accounts came to us after failed switchovers. Projects halted by uneven color, failed flow tests, or excessive volatile residues pushed them away from less scrupulous sources. We take these “firefighting” calls seriously; on a daily basis, our technical team fields remote troubleshooting requests and offers lot-based analysis support to quickly rule out or confirm possible raw material causes.
Keeping product within spec at each point—raw materials entry, in-process sampling, post-packout—gives real leverage against disruptions. Manufacturer-level control means we don’t depend on traders’ claims; we know our supply chain, because any batch that fails spec doesn’t leave the lot. If a QC challenge surfaces in the field, we track back using our archived reference samples and batch cards, often discovering the story behind a customer’s out-of-spec reaction lies with process tweaks miles downstream, not in the chemistry itself.
Connections between technical teams make the world of difference. It’s one thing to ship a product and wait for repeat orders; it’s another to pick up the phone and guide a customer through process fixes, adjustment of reaction temperature, solvent swaps, or improvements to addition order. We spend hours each week consulting, either live or over detailed data files, to help users make subtle changes that sharply improve conversion or filterability.
Real feedback comes not from glowing reviews but tight-lipped notes on things that could work better—maybe particle size ranges drifted, or compaction changed year-on-year. This critical loop is what makes manufacturing satisfying and challenging; it’s a long game. Years ago, a client in pigments flagged a faint yellow shift during scale-up. We ran retained lots through replica reactions, analyzed for oxidative byproducts, and worked backward through utility water and storage records until we isolated the culprit: a faulty glove leading to trace iron contamination. Only by keeping our archive and sharing openly did we solve both their problem and our own blind spot.
Supply volatility hits every sector. We source our starting materials from a handful of trusted vendors, many maintained over a decade. During global disruptions, redundancy in supply and storage keeps us from scrambling for substitute inputs. Our logistics group maps lots from drums to finished packets, ensuring we keep production buffers padded without slipping in grade or origin.
Sudden surges in demand can stretch our campaign schedule thin. We answer requests for increased spot volume by doubling down on process coordination, often adding extra shifts and running cross-checks on new lots before approving scale-up. Through every stretch, batch documentation and specification adherence prevent short-term relief from causing long-term regret—a lesson captured in every after-action review, and continuously shaping the way we manage both people and process.
We keep detailed tracking not to satisfy policy, but to swiftly respond when a partner requests proof of origin, storage, or analytical matching. This direct line from manufacturer to user ensures reliability in applications that don’t forgive slip-ups.
Every drum of 2,6-Dichlorobenzylamine is a snapshot of continuous improvement—raw input checked against last shipment, yields trended against historical averages, and every step measured for both process economy and final quality. As a producer, our best work gets tested in the field, not the lab. Off-label uses, one-off problem-solving, and new syntheses push our teams to stay flexible and adapt fast.
Requests for tailored specs, micron sizing, or solvent-free grades come in regularly. We don’t claim universal compatibility, but for legitimate use-cases, our technical service team works through pilot studies, provides reference batches, and shares results candidly. This transparency, rarely seen in trading houses or brokers, powers real innovation. Users feel safe trialing a process when they know where and how their raw material was made.
Partnerships formed over shared troubleshooting and honest failure reports last much longer than those based only on price or list specification. A manufacturer’s work doesn’t end at the loading dock. Our chemists and operators often work hands-on with downstream engineers or R&D managers, digging through data and tracing production history to help isolate variables. The path from process hiccup to full correction can stretch weeks, but real learning only happens when communication lines run both ways.
Industry never stands still. Regulatory bodies continue to increase spectral scrutiny on trace byproducts, especially where pharmaceutical APIs or food-adjacent uses come into view. We respond by pushing our in-house techniques—advancing from basic titrations and melting point checks, to fully documenting with LCMS and more exhaustive impurity panels. As new applications emerge, patents filed yearly show inventive chemists exploring this compound for niche catalysis, materials science, and specialized dyes. Each new use-case invites a new round of bench testing and method validation, often with directly shared samples.
Transitioning from legacy lots to improved high-purity variants takes more than a spec sheet. We work alongside users during trial phases, providing small-lot runs for parallel testing, and documenting how new purification steps improve process efficiency or reduce downstream risk. Over time, users see the benefit not just in yield, but in their own capacity to troubleshoot less, waste less, and push production cycles harder. Producer-level diligence roots every successful partnership; those long investment cycles in better plant tooling and process intelligence always outpace short-term cost savings.
The value of 2,6-Dichlorobenzylamine—any manufacturer-quality intermediate—does not rest solely on purity or pack size. It’s the lived experience behind sourcing, production, and technical support that defines why industrial buyers return. Our team puts a premium on hard-won knowledge, open reporting, and steady handoffs from raw material input, through isolation and purification, down to the seal on each shipment. Customers who buy direct don’t just save on cost; they gain a troubleshooting partner, a technical resource, and a reliability buffer seldom matched in a landscape of brokers and intermediaries. Real trust comes not from claims, but from visible competence, batch after batch, year after year.