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HS Code |
910930 |
| Cas Number | 3964-56-5 |
| Molecular Formula | C6H3Cl2NO3 |
| Molecular Weight | 224.00 |
| Iupac Name | 2,6-dichloro-4-nitrophenol |
| Appearance | Yellow crystalline powder |
| Melting Point | 180-183°C |
| Boiling Point | Decomposes before boiling |
| Solubility In Water | Slightly soluble |
| Density | 1.67 g/cm3 |
| Pka | 6.83 |
| Synonyms | 2,6-Dichloro-4-nitro-1-hydroxybenzene |
| Pubchem Cid | 18445 |
| Ec Number | 223-417-8 |
As an accredited 2,6-Dichloro-4-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 2,6-Dichloro-4-Nitrophenol, with a red hazard label and tamper-evident cap. |
| Shipping | 2,6-Dichloro-4-Nitrophenol should be shipped in tightly sealed, chemical-resistant containers, protected from light, moisture, and incompatible substances. Label packages with appropriate hazard warnings and handle according to local and international chemical transport regulations. Ensure compliance with UN shipping guidelines for hazardous materials to guarantee safe transit and delivery. |
| Storage | **2,6-Dichloro-4-nitrophenol** should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers and bases. The storage area should be clearly labeled and equipped with spill containment measures. Personal protective equipment (PPE) should be used when handling the chemical. |
Applications of 2,6-Dichloro-4-Nitrophenol in Industrial ManufacturingAs a producer of 2,6-Dichloro-4-Nitrophenol, we serve established industrial sectors that incorporate this fine chemical as a functional ingredient in their core processes. Our technical team works closely with downstream operations to ensure efficient integration, consistent quality, and compliance with relevant guidelines at each application stage. 1. Intermediate for Agrochemical SynthesisMajor crop protection manufacturers employ 2,6-Dichloro-4-Nitrophenol as a key intermediate during synthesis routes for selective herbicide actives, particularly in phenol-derived post-emergence products. It enters the synthetic chain after chlorination and prior to amide or ester group introduction, supporting site-specific modifications desired by modern agrichemical developers. This approach allows precise control over impurity profiles to meet regulatory and application performance requirements for finished agrochemicals. Industry compliance standards
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2. Intermediate for Pharmaceutical Synthesis (Active Pharmaceutical Ingredient Pathways)Leading API manufacturers utilize this compound as a building block in multi-step syntheses for specific antimicrobial and antiprotozoal drugs. Its electron-withdrawing substituents enable regioselective coupling in aromatic substitution, crucial for preparing nitroaromatic scaffolds. This stage impacts both impurity control and final product performance, particularly for generics and off-patent molecules aligned with global pharmacopoeia requirements. Industry compliance standards
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3. Colorant Precursors for Polymer AdditivesMajor polymer compounders process 2,6-Dichloro-4-Nitrophenol to prepare specialty azo and nitro-based colorants for plastics where thermal and UV stability are essential, such as outdoor and automotive grades. These downstream producers integrate the compound via coupling reactions with aromatic amines, followed by polymer compatibilizer blending during pelletizing, ensuring strong chromatic persistence and minimal migratory risk in end-use applications. Industry compliance standards
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4. Synthesis of Analytical Reagents for Laboratory UseManufacturers of diagnostic test kits and analytical chemistry reagents employ this nitrophenol as a chromogenic substrate, functionalized during synthesis of detection agents for routine laboratory protocols, including enzyme activity assays and trace heavy metal analysis. Consistency in crystallinity and purity ensures low background interference, while production follows stringent laboratory reagent benchmarks for both research and regulated diagnostic applications. Industry compliance standards
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At our plant, 2,6-Dichloro-4-Nitrophenol is produced with the kind of focus that only comes when you work hands-on with every synthesis batch. We’ve spent years fine-tuning each step so the finished product meets our own strict criteria before it ever leaves the reactor. Most chemists outside our circles don’t get to see the root of quality; they receive the drum at the loading dock and trust the label. We don’t have the luxury of shortcuts or half-measures, which means each run involves real scrutiny at the interface of raw material sourcing, process control, and precision drying. Variability creeps in if a team lets diligence slip for a moment—not just in color or clarity, but in purity itself.
The best proof sits in years of collaboration with partners who rely on consistent coloration and solubility for downstream work. No batch ships before running a suite of in-house tests—melting point, HPLC trace, and spectral fingerprints confirm structure and confirm we haven’t missed the mark. In this way, we have built a line of product that satisfies requirements in dye intermediates, specialty pigments, pharmaceutical research, and advanced materials.
Chemists use 2,6-Dichloro-4-Nitrophenol for more than one purpose. In one corner of the market, this molecule acts as an intermediate in systems where its unique electron-withdrawing nitro group and double chlorination allow for custom downstream substitutions. A different sector demands it as a stable chromophore, crucial for imparting color under challenging pH or solvent conditions. Each end user wants a slightly different extension of purity, color intensity, or particulate size—but nobody tolerates broad deviations batch-to-batch. We hear from project leads who spotted issues with off-spec product from brokers and resellers: mislabeling, variable melting point, trace contaminants that ruin analytics. That’s a headache we don’t send down the supply chain.
Our granulation process—with consistent, moderate particle size and a crisp yellow hue—mirrors the demands we set for our own downstream processes. Control of particle size cuts down on dust and loss, helps in metered dispensing, and streamlines dissolution. Finer or uneven product leads to headaches in production, so we maintain every step ourselves, from recrystallization to drying.
From the scale-up perspective, we offer 2,6-Dichloro-4-Nitrophenol in multiple package sizes, configured for both research and industrial bulk consumption. Chemists running analytical work often request smaller glass containers, while manufacturing clients in textile chemistry or agrochemical research need bags or steel cans with robust seals. Regardless of the external container, every lot passes through the same analytical checks at our lab. While we once handled reactions in glassware small enough to sit on a workbench, we now charge reactors sized for hundreds of kilos, but the test criteria haven’t relaxed.
A sample chromatogram accompanying each lot means researchers see what we’ve measured: single peaks where expected, no carryover from the prior run, and background noise at its lowest. We do not substitute grades or cut corners on drying—ambient trace water can ruin sensitive subsequent steps, so our final product sits comfortably within the 99.0%+ purity mark, with traces of precursor or residual solvents kept significantly below levels that would disrupt high-consequence syntheses. Achieving this consistency requires vigilance from operators, constant checks on utility feeds, and a real commitment from every lab tech.
You’ll find 2,6-Dichloro-4-Nitrophenol living at the intersection of specialties. Manufacturers of organic pigments value its high reactivity; it offers a platform where tailored substituents add brilliance or longevity under UV and chemical challenge. In the pharma sector, researchers leverage its electron-deficient aromatic ring for coupling with nucleophiles, leading to libraries of modified compounds ready for screening. Certain textile pigment operations demand a stable optical brightness and compatibility within complex mixtures—offered only by strict isomeric control and minimal color-shifting impurities.
Innovation stems from the reliability of the building blocks. In our time supplying custom chemistries to R&D teams, we’ve seen the difference that minor off-spec issues introduce. A slight increase in residual solvent derails a solid-phase process or contaminates a new pigment mixture, wasting days of work. In this environment, consistency is not just desirable. It’s fundamental to the next step in research or scale-up.
We also see demand from companies developing pesticide intermediates, polymer chain extenders, and specialty inks—where the nitro and chloro substituents give new routes to modified materials. Every downstream process introduces new parameters, and a batch survivor must clear hurdles for solubility, spectral purity, and absence of colored by-products.
After watching competitors operate, we see the temptation to shortcut—the batch that ships without a full round of QC; the container sealed with hope rather than data. Most commodity brokers operate sight unseen, blending lots of mixed origin, claiming compliance without local analysis, and delivering product more fit for bulk dye blending than reproducible fine chemicals. We see customer questions like, “Why doesn’t this dissolve properly? Where’s the transparency?” These frustrations all trace back to a disconnect from the actual chemistry.
Our in-house controls cut through that uncertainty. Sourcing never relies on external traders; each precursor arrives only after a round of supplier audits and spot-testing. Our finished product undergoes repeated checks for isomer identity, residual colorants, by-product fingerprinting, and a contamination check for common process catalysts. When someone requests a batch for a highly scrutinized pharmaceutical step or a pigment with no room for color drift, we provide individual lot certifications and published spectra. With a laboratory adjacent to the production line, our chemists answer for each run.
Batch uniformity does not survive inconsistent temperature ramps or neglected equipment maintenance. Over the years, we have seen how minor lapses—dust on a filter, slight miscalibration of a dosing pump—introduce real-world deviation that cascades into larger issues. The market does not forgive those lapses; customers remember which supplier required the least follow-up. By working only as a direct producer, not as a reseller, we stay personally responsible for each gram that moves from our reactor to your laboratory.
Beyond apparent quality, safety remains central. Unverified material often contains trace metals, halide scavengers, or leftover catalysts, any of which threaten analytical or scale-up work. We monitor for the most likely agents left from nitration, halogen exchange, or related reactions. Even the color of the crystals signals things: faint hues point to by-products, off-white specks confirm trace insolubles.
Teams performing large-scale syntheses have learned to test for each parameter themselves—often at the expense of time spent troubleshooting. We lessen that burden with documented reproducibility. The headache from a contaminated batch—scrapped high-value intermediates, repeated purification, or abandoned syntheses—drives a preference for suppliers who handle the entire process in-house. In this business, losing a day means more than missed quotas; it can damage trust with your own customers, and that reputation is expensive to rebuild.
Ever since we scaled to industrial production, every adjustment to raw material, vessel type, or solvent has needed thorough validation. This means that even after years in the field, new variables surface—climate affects crystallization dynamics, seasonal changes demand tweaks to dryer settings, and subtle shifts in water content ripple through the final material quality. By investing in closed-loop feedback from end users and regular retraining, we pick up on minor trends before they escalate.
From a chemist’s bench perspective, the less time lost to rework, the more resources spent advancing new applications. Large-scale users require repeatable characteristics, whether blending with solvents, adding to masterbatches, or applying via printing technology. Each sector calls for different specs, but everyone benefits from transparent documentation and direct support.
We work with chemists pushing the envelope on new conjugated materials, ink developers pressing for brighter, more durable shades, and agrochemical teams needing intermediates with predictable stability. Our own experience guiding clients through process validation has shown us the shortcomings of silent suppliers, bland certificates pasted to a shipment, or blame passed between layers of middlemen. Direct lines between producer and user mean questions get answered quickly, and process improvement moves in real time.
Advancements in analytical chemistry make shortcuts harder to hide. Modern HPLC, NMR, and elemental analysis uncover off-spec points previously masked in average samples. We welcome requests for duplicate testing and even third-party verification. In this ecosystem, openness pays off.
Working through the cycles of pilot runs and scaling operations, we know the pain points: delays due to unclear product design, wasted resources on failed colorants, and pulled orders when regulatory needs change. Our staff traces each batch from precursor arrival to final drum—logging temperature swings, pH checks, and even the micro-level ambient conditions during crystallization.
Such documentation lives not for its own sake, but to show—if a pigment processor in India or a research operation in Europe asks—exactly what went into a given lot. Traceability justifies itself at audit time. It also reassures high-value users whose own certifications demand documented input chemicals from each upstream provider.
Adaptability follows from direct production control. Customer needs evolve, regulations shift, and new guidelines from chemical markets appear every few years. A production team close to its own chemistry can adjust drying cycles for local climates or introduce upgraded synthesis steps when regulations tighten. We make these changes not just to comply, but to lead by example—proving to long-term customers that we are ready to document and adapt as their needs change.
Transparency doesn’t rest at the point of sale. Post-shipment inquiries, requests for additional characterization, and even trace impurity breakdowns arrive from clients scaling up or validating new product lines. Our lab tackles these questions in-house, and we see few calls for major adjustments after the fact. This supports troubleshooting and encourages feedback; if an unexpected issue ever emerges, we investigate at the site of production and respond with actionable data.
Sustainable operations matter. Each chemical batch affects more than just the final product; it impacts workers, communities, and downstream customers exposed to environmental or regulatory scrutiny. Our plant follows current environmental controls—not just checking boxes for permits, but running waste solvent treatment, water recycling, and air emission controls up to documented global benchmarks.
The benefit here is two-fold: less material waste, and peace of mind for buyers audited on their supply chain’s environmental footprint. Our clients operating with stricter standards, especially in the EU and North America, have verified our chain-of-custody documentation for compliance with new rules. Procurement officers report that enjoying reliable audit outcomes helps them maintain relationships with their own customers, who cannot risk regulatory shutdowns.
By keeping full process records and retracing every input, we help partners demonstrate origin in a field where mislabeling and gray-market intermediates put compliance at risk. In our industry, eliminating uncertainty up front saves everyone trouble down the line.
Through years of refining 2,6-Dichloro-4-Nitrophenol production, we’ve learned that continual improvement drives both market trust and technical results. As new applications appear—niche electronics, specialty coatings, advanced pharmaceuticals—product requirements tighten further. Material that qualified a decade ago now faces additional scrutiny for trace elements, particulate size, and even background organic signatures.
Our quality team stays locked in with customer research teams, industry consortia, and international standard-setting groups. The goal isn’t just to meet today’s sales—it's to set benchmarks for chemical producers globally. Clean, traceable, reproducible product, created by technicians who see the entire chain firsthand, forms the backbone of new science and reliable manufacturing.
Even with legacy products like this, there’s room to support technical advance. In the end, every new pigment, stabilized polymer, or advanced pharmaceutical relies on the soundness of its starting materials. We carry that responsibility at each step so our end users can build, innovate, or discover, supported by chemistry rooted in firsthand diligence and continuous oversight.