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2,6-Dibromonaphthalene

    • Product Name 2,6-Dibromonaphthalene
    • Alias naphthalene, 2,6-dibromo-
    • Einecs 211-954-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    355143

    Chemical Name 2,6-Dibromonaphthalene
    Cas Number 580-18-7
    Molecular Formula C10H6Br2
    Molecular Weight 313.97 g/mol
    Appearance White to off-white solid
    Melting Point 154-157 °C
    Boiling Point 355 °C
    Density 1.92 g/cm³
    Solubility In Water Insoluble
    Flash Point 167 °C
    Purity Typically ≥98%
    Smiles Brc1ccc2ccccc2c1Br
    Inchi InChI=1S/C10H6Br2/c11-7-3-1-5-9-6-2-4-8(12)10(7)9/h1-6H
    Refractive Index 1.73 (Predicted)
    Storage Conditions Store in a cool, dry place

    As an accredited 2,6-Dibromonaphthalene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 25g 2,6-Dibromonaphthalene is sealed in an amber glass bottle with a tightly capped lid and hazard labeling.
    Shipping 2,6-Dibromonaphthalene is packaged in tightly sealed containers to prevent moisture and contamination, and is shipped in accordance with hazardous material regulations. The containers are clearly labeled, and appropriate documentation accompanies the shipment. Handle with care, avoid exposure to heat, and store in a cool, well-ventilated area during transport.
    Storage 2,6-Dibromonaphthalene should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and ignition sources. Keep it in a tightly closed container, compatible with organic chemicals. Store separately from strong oxidizers and acids. Ensure containers are properly labeled, and access is restricted to trained personnel. Follow all local regulations and safety guidelines for hazardous chemicals.
    Application of 2,6-Dibromonaphthalene

    Applications of 2,6-Dibromonaphthalene in Industrial Manufacturing

    2,6-Dibromonaphthalene serves as a strategic intermediate in the synthesis of specialty chemicals, advanced materials, and agrochemical actives. Its molecular structure supports precise halogenation requirements in high-value applications across the chemical industry. As a raw material manufacturer, we observe its use in tightly regulated sectors, where purity, batch consistency, and validated pathways remain essential for customer operations.

    1. Advanced Organic Electronics: OLED Intermediate Production

    The electronic materials industry frequently employs 2,6-dibromonaphthalene as a building block in synthesizing functionalized naphthalene derivatives, especially for organic light-emitting diodes (OLEDs). Manufacturers require this intermediate for subsequent cross-coupling reactions, enabling the production of key monomers for emissive or transport layers with defined molecular alignment and electronic properties. Material qualification demands detailed batch traceability and compliance with specific electronic material standards, supporting the fabrication of high-performance display panels and lighting modules.

    Industry compliance standards

    • SEMI MS4 (Materials Specification for Organic Materials in Electronics)
    • IEC 62679 (OLED display evaluation and test methods)
    • ISO 9001:2015 (Quality Management Systems for electronic industry manufacturers)
    • IPC-4101 (Base Materials for Printed Boards, where organic intermediates are utilized for functional lamination processes)

    Typical usage ratio

    • 3–10% loading in cross-coupling monomer synthesis, depending on the target molecular design and product yield optimization
    • Adjustment based on final layer thickness and electronic performance specifications defined by downstream device requirements

    Downstream process integration

    • Introduced at the initial halogenation stage during Suzuki or Stille coupling synthesis schemes for OLED monomers
    • Used in high-purity, solvent-controlled reactors under nitrogen atmosphere to protect electronic functionality
    • Processed through activated carbon purification prior to polymerization, ensuring minimal contaminant migration into sensitive thin-film devices

    Final product types

    • Emissive layer monomers for OLED panel manufacturing
    • Transport molecule precursors for electronic devices
    • Organic semiconductor materials
    • Specialty light-emitting polymers for advanced flat panel displays

    2. Pharmaceutical Intermediate Synthesis: Active Ingredient Formation

    2,6-Dibromonaphthalene is widely used as a halogenated aromatic starting material in pharmaceutical manufacturing, supporting downstream production of bioactive naphthalene-based compounds. Custom synthesis teams rely on its reactivity for directed metalation or cross-coupling, progressing to target molecules with rigorous impurity profiles. Process development requires strict adherence to international pharmacopoeial standards and Good Manufacturing Practices. Analytical documentation, in-process controls, and trace solvent management are closely monitored to support regulatory submissions and batch release for clinical and commercial supply.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • EDQM (European Directorate for the Quality of Medicines) certification
    • USP <823> and <1078> (handling and purification of pharmaceutical intermediates)
    • 21 CFR Part 210/211 (US FDA cGMP regulations for drug products)

    Typical usage ratio

    • 0.5–5% of total input for the target compound's synthesis phase, calculated relative to the limiting reagent or active core structure
    • Adjusted for stoichiometric incorporation based on desired pharmaceutical yield and scale-up campaign

    Downstream process integration

    • Charged during the early synthetic step for directed ortho-metalation or used as the halogen source in Grignard and Buchwald–Hartwig processes
    • Reaction performed in GMP-certified vessels, with online HPLC monitoring for residual bromide tracking
    • Intermediates subjected to phase separation, crystallization, and solvent stripping prior to downstream derivatization

    Final product types

    • Naphthalene-derived pharmaceutical intermediates
    • Anti-cancer agent precursors
    • Targeted enzyme inhibitor synthons
    • Core building blocks for CNS-active drugs

    3. Agrochemical Active Compound Development

    The crop protection industry utilizes 2,6-dibromonaphthalene in the creation of halogenated naphthalene derivatives for herbicides and fungicides. Here, the compound’s bromine atoms guide regioselective functionalization at downstream stages, enabling precise control over bioactive molecular architecture. Agrochemical manufacturers must satisfy global regulatory frameworks on residuals, toxicity, and environmental impact, running dedicated pilot plant trials for registration dossiers. Raw material traceability and impurity mapping are prioritized in response to pre- and post-market surveillance requirements.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • OECD Guidelines for Testing of Chemicals (ecotoxicology and residue analysis)
    • ISO 17025 (Agricultural QC laboratory accreditation)
    • EU 1107/2009 (Plant Protection Products Regulation)

    Typical usage ratio

    • 1–8% of target formulation weight, depending on downstream functionalization and final product registration batch scale
    • Modified based on required selectivity and impurity content

    Downstream process integration

    • Utilized at the chlorination or alkylation step for functionalizing naphthalene rings in anhydrous conditions
    • Processed in stainless steel loop reactors to prevent halogen cross-contamination
    • Samples sent for accelerated storage and soil leaching studies after pilot synthesis

    Final product types

    • Pre-emergent herbicide precursors
    • Anti-fungal agent intermediates for crop protection
    • Naphthyl-based insect growth disruptors
    • Raw material in developing new-generation pesticide actives

    4. Specialty Dye and Pigment Manufacturing

    Specialty pigment and dye producers exploit the dual bromination pattern of our product to synthesize advanced, high-purity colorants with demanding lightfastness or thermal requirements. Its halogenation facilitates targeted azo coupling, sulfonation, or acid dye extension, delivering color bodies suited for textiles, technical plastics, and high-performance inks. Large-scale facilities tightly control raw material lot traceability, implement color strength standardization, and comply with international safety and eco-labeling benchmarks.

    Industry compliance standards

    • OEKO-TEX Standard 100 (textile dye product safety)
    • REACH Regulation (EC 1907/2006) for chemical safety in colorant production
    • DIN EN 71-3 (safety of toys – migration of certain elements, for pigments in children’s items)
    • ISO 9001:2015 and 14001:2015 (Quality and Environmental Management Systems for colorant production)

    Typical usage ratio

    • 0.5–2% in initial pigment molecule synthesis, calculated by molar equivalence to coupling/capping reagents
    • Adjusted to achieve target hue intensity and fastness properties in end-use dye formulation

    Downstream process integration

    • Fed into the azo coupling or electrophilic substitution stage within closed reactor systems under continuous agitation
    • Treated through phase separation, acid washing, and neutralization prior to granulation or spray drying
    • Finished pigment batches tested for particle size, color strength, and residual bromide content

    Final product types

    • High-purity naphthalene-based pigments for plastics and fibers
    • Lightfast dyes for automotive coatings and industrial textiles
    • Brominated colorants for inkjet printing and specialty inks
    • Color additive intermediates for synthetic leather and engineered surfaces
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    Certification & Compliance
    More Introduction

    2,6-Dibromonaphthalene: Built for Consistency in Chemical Synthesis

    Long Experience Shaping Our Approach

    At our manufacturing site, the line between the ordinary and the exacting separates good products from what our customers actually depend on. We put decades of hands-on engagement with aromatic brominated compounds into every batch of 2,6-Dibromonaphthalene we produce. Chemists working on pharmaceuticals, performance polymers, or specialty dyes often stop by to discuss subtle variations in reactivity, solubility, or trace impurities. Many of their questions focus on 2,6-Dibromonaphthalene because of its role in advanced organic syntheses, especially where controlled substitution on the naphthalene core makes or breaks a multi-step process.

    A Close Look at 2,6-Dibromonaphthalene

    2,6-Dibromonaphthalene, with its two bromine atoms precisely attached to the naphthalene ring at the 2 and 6 positions, offers a unique balance between activity and selectivity. This molecular structure serves more than just academic interests; it determines how the molecule behaves in real-world transformations, from Suzuki couplings and transition metal-catalyzed reactions to more specialized uses in liquid crystals and OLEDs. By controlling the precise location of the bromine substituents, we help researchers achieve higher yields and fewer side products. We use our own high-purity process to minimize contaminants, because even trace isomers or halogenated byproducts result in purification headaches downstream.

    Specifications Reflecting Practical Demands

    Over the years, we have fine-tuned our 2,6-Dibromonaphthalene offering in response to both routine and high-stakes customer feedback. Our product, catalogued internally as Model 2,6-DBN2024, consistently reaches a chemical purity of 99.5% or higher by GC, supporting confidence for synthetic routes with strict requirements. Appearance matters too; we deliver a well-defined, white to off-white crystalline powder, an attribute appreciated by labs and plants that want straightforward weighing and handling without messy stickiness or dust clouds.

    Melting point always comes up in conversations with regular users. We control ours within the 164–167°C range, so you see reliable thermal behavior in both scale-up and bench settings. Moisture and residual solvent contaminants stay well below 0.2%—a threshold set through years of talking with process chemists dealing with caking and reactivity issues. By regularly running advanced chromatographic analysis, we catch microlevel impurities that can easily be missed in a batch-based manufacturing environment.

    How 2,6-Dibromonaphthalene Sets Itself Apart

    Some folks new to the field ask what makes 2,6-Dibromonaphthalene different from mono- or other dibromo analogues like 1,5- or 1,4-dibromonaphthalene. The answer sits at the intersection of molecular geometry and chemical reactivity. The 2,6-substitution pattern locks the molecule into a conformation especially well-suited to forming selective cross-coupling products. This arrangement allows reaction partners easier access to the reactive sites, compared to the more congested positions in 1,5- or 1,8-dibromonaphthalene.

    As one example, in the construction of key biaryl linkages for advanced materials, the placement of the bromine atoms at the 2 and 6 positions sidesteps steric clashes that complicate coupling of other dibrominated isomers. If a user substitutes 2,6-Dibromonaphthalene with a less controlled dibromo isomer, the complexity of downstream purification and risk of forming unwanted products can grow rapidly. In our own pilot processes, swapping between different brominated naphthalenes shows dramatic differences in yield, purity, and even product color—a factor that can tip the scale between commercial success and setbacks in scale-up campaigns.

    Applications Growing Through Experience

    The main buyers for our 2,6-Dibromonaphthalene are researchers and manufacturers tackling custom building blocks for pharmaceuticals, high-performance polymers, and functional dyes. As an intermediate, it helps bridge diverse downstream chemistry, making it a key part of Suzuki-Miyaura and Heck-type coupling processes. By using a reliably pure and specifically substituted material, polymer scientists report fewer issues with branching or inconsistent chain lengths compared to starting materials with mixed isomers.

    Beyond polymer chemistry, 2,6-Dibromonaphthalene enables the synthesis of molecular materials used in modern electronic displays, OLEDs, and advanced sensor platforms. Material engineers visit the plant and point out how even subtle contamination—such as left-over dibrominated structural isomers—can degrade device performance by introducing charge traps or changing crystallization behavior.

    We also see its uses stretching into agrochemical research, particularly where selectivity and functional customization play central roles. By working directly with labs pushing boundaries in molecule design, we understand the pressure to minimize troubleshooting caused by inconsistent starting materials.

    Experience Building Stable Supply Chains

    Anyone dealing with specialty chemicals knows the pattern: today’s hot intermediate becomes tomorrow’s critical bottleneck if quality falls short or logistics stumble. We set ourselves apart by manufacturing at a single, integrated site with years of proven reliability. When raw material cost spikes or energy prices swing, our operations crew invents sustainable solutions for uninterrupted output. Last year, one major customer avoided weeks of lost production because our team flagged a potential capacity crunch months in advance and secured the extra bromine feedstock early.

    Because labeling purity and reality sometimes diverge, we ship with the same full certificate of analysis we rely on ourselves for in-process controls. We also developed a formal system for traceability, so chemists using our 2,6-Dibromonaphthalene can match a vial in their lab directly to our archived QC data, lot by lot. Problems such as batch-to-batch variation, previously feared by many seasoned chemists, now show up as rare exceptions, not regular frustrations.

    Tackling Process Challenges

    Synthesizing 2,6-Dibromonaphthalene isn’t a trivial exercise in adding two halogens onto naphthalene. The reaction pathways create potential for overbromination, ring-opening, or formation of off-target isomers. Many commercial suppliers settle for a mixture of dibromonaphthalenes, but our team, from plant operators to R&D scientists, stays focused on selectivity at each reaction stage. By maintaining strict control over temperature and stoichiometry, we consistently suppress formation of 1,5- or 1,8-dibromonaphthalene, which can sneak into a poorly monitored batch and cause headaches downstream.

    Experience has taught us how little things like atmospheric humidity or minor pressure swings can shift product profiles. We developed an in-house reactor monitoring system that tracks critical variables in real time, alerting both operators and chemists. If a run starts drifting outside of optimized limits, we adjust process parameters on the spot. This close watch lets us build batches that both our team and customers trust—whether someone’s running a micro-scale library synthesis or multi-ton industrial campaign.

    By controlling these variables from raw material inspection through final crystallization, we avoid most common pitfalls. If a new problem arises—like an unknown peak appears in GC or a batch fails thermal stability screening—we hold the product, search for the cause, and only ship material after root cause analysis, not because of a looming order deadline.

    Sustainability and Worker Safety Embedded in Every Step

    Manufacturing 2,6-Dibromonaphthalene involves handling reactive halogenated intermediates, organic solvents, and byproducts that require careful management. We built solvent recovery loops to recycle and purify what would otherwise become chemical waste. Plant technicians brought in practical suggestions from their years on the floor, helping us reduce solvent losses and environmental downtime. Local regulatory agencies visit and walk our floors without advance notice; they don’t find half-empty drums or makeshift dumping. We stake our business on this visible, ongoing commitment because not just customers, but every person working on or near these processes, feels the consequences.

    Teams train for the “what ifs”—from leaks to unusual spikes on reactor charts. No incident goes uninvestigated. Those repeating tasks, filling drums or monitoring distillation columns, know they have permission to stop work if anything seems even slightly off. These measures might not show up in a final jar of 2,6-Dibromonaphthalene, but they protect both our people and the wider environment.

    Building for Tomorrow: Anticipating Shifts in Chemistry

    Over many years, customers have introduced us to unexpected new uses for the familiar 2,6-Dibromonaphthalene. As material science trends shift towards more sustainable or functional advanced materials, cleanly brominated aromatics help these fields push boundaries. Our in-house R&D line listens closely for changing structure–property relationships, so product improvement keeps pace with evolving needs, not just today’s requests. We regularly hear from start-ups and university groups who need a slightly modified batch—perhaps with differentiated isotopic labeling for tracer studies or ultra-trace purification for optoelectronic device work.

    We treat these challenges as essential learning. Improving 2,6-Dibromonaphthalene supply means staying flexible, ready to pivot on process upgrades, and willing to make continuous small changes. Technicians and chemists huddle together for ongoing review meetings, sharing lessons learned from on-site troubleshooting, new analytical techniques, and customer feedback. Ongoing investment in analytical equipment and skills pays off quickly—sometimes with new approaches to long-standing bottlenecks, such as enhancing separation of regioisomers or optimizing recrystallization protocols.

    In our view, steady improvement in process repeatability, analytical transparency, and sustainability doesn’t just benefit us as a manufacturer. These changes expand what chemists everywhere can achieve, allowing ideas that once sat on the edge of practicality to become viable, scaled commercial routes.

    Why Thoughtful Manufacturing Makes a Difference

    After thousands of batches and countless conversations, one lesson remains clear: no downstream chemistry works better than the quality of upstream building blocks. By putting real energy into characterizing, purifying, and documenting 2,6-Dibromonaphthalene, we supply more than a single chemical—we offer confidence for everything built with it. Customers don’t just order kilograms from us; they call, email, or visit, raising critical questions about residual solvents, reaction compatibility, and storage. Our answers grow directly from work on the plant floor and direct troubleshooting, not sales meeting scripts.

    Some customers who first came to us expecting “standard” dibromonaphthalene returned months later, asking about problems encountered with alternate suppliers: opaque purity claims, unexpected impurities, and finger-pointing over tracing root-causes. After troubleshooting, comparisons, and process adjustment, many shifted to our 2,6-Dibromonaphthalene for its consistent analytical profile and the accessibility of our technical support. We respond openly about analytical data because we've touched the product in every stage: from raw material check to weighing, reaction optimization, and shipment.

    Continuous Dialogue With the Field

    We devote considerable time to listening. By actively participating in technical symposia, trade meetings, and customer site visits, we stay tuned to both routine needs and forward-looking shifts in fields like advanced polymers, electronic materials, and pharmaceutical intermediates. Real-world stories from bench chemists and plant managers help us spot trends—demand for purer or differently formulated 2,6-Dibromonaphthalene, rising regulatory scrutiny, or requirements for recyclable packaging.

    We put feedback to work by refining our process and tweaking scale-up protocols. When a customer shares an insight about a new catalytic sequence or a problem with storage life, this isn’t lost in a suggestion box—it’s debated, tested, and, when practical, turned into action. In our experience, the best improvements to 2,6-Dibromonaphthalene production—tighter impurity control, more consistent crystal morphology, or improved shipping protocols—flow from this ongoing dialog rather than isolated, top-down decisions.

    Navigating Challenges in a Changing World

    Regulatory shifts, global supply chain tensions, and market volatility present real risks in specialty chemical supply. We invest in inventory buffers, local raw material partnerships, and a deep bench of experienced plant staff who know how to run equipment, interpret analytical data, and respond to unexpected process signals. During periods of shipping constraints or regulatory updates, our group doesn’t lean on risky shortcuts or diluted quality. We ramp up direct communication, share facts openly with customers about our capacities or delays, and seek creative solutions, such as breaking larger shipments into staged deliveries or exploring new logistics channels.

    Pain points do not vanish, especially with international movement of hazardous substances. Still, by working closely with customs compliance, aligning with up-to-date regulatory frameworks, and training our logistics team to anticipate new hurdles, 2,6-Dibromonaphthalene arrives on time, in-spec, and with complete documentation. These efforts don’t just keep our customers running; they keep skilled specialists employed and boost transparency across the sector.

    A Partnership View, Not Just a Transaction

    Supplying 2,6-Dibromonaphthalene goes beyond filling purchase orders. We value the ongoing connections that form between our production staff and the technical teams using our product. By sharing ideas, practical lessons, and technology updates, we make each batch an improvement over the last, keeping pace with industry advances.

    In chemical manufacturing, experience and attention to quality leave a visible trail—clear analysis reports, open communication, and batches that support cleaner, faster synthesis. Through direct conversations, process upgrades, and shared successes, 2,6-Dibromonaphthalene stands as a practical example of what’s possible when a manufacturer puts know-how and customer needs at the center, supporting progress in science and production far beyond the naphthalene ring.