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HS Code |
167438 |
| Iupac Name | 2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethan-1-ol |
| Molecular Formula | C12H13NO2 |
| Cas Number | 132265-16-6 |
| Appearance | White to off-white solid |
| Solubility | Soluble in common organic solvents |
| Purity | Typically >98% |
| Storage Condition | Store in a cool, dry place, tightly closed |
| Smiles | CC1=CN(C(=O)O1)C2=CC=CC=C2CCO |
As an accredited 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, 25g, with tamper-evident cap, white label displaying chemical name, formula, hazard pictograms, and batch information. |
| Shipping | This chemical, 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol, is shipped in securely sealed containers compliant with chemical safety regulations. Packaging includes cushioning to prevent breakage and is labeled according to international standards. All shipments are accompanied by the appropriate safety data sheets and documentation for regulatory and safe handling during transit. |
| Storage | Store 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)ethan-1-ol in a tightly sealed container, in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers or acids. Ensure storage conditions avoid moisture and humidity. Clearly label the container and follow all relevant safety guidelines for handling and storing organic chemicals. |
Applications of 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol in Industrial Manufacturing2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol serves as a precision intermediate within specialty chemical synthesis, particularly supporting advanced pharmaceutical, agrochemical, and polymer innovation. As direct manufacturers, we engage in multi-stage synthesis with established downstream industries, delivering this raw material with precise purity and validated specification control. 1. Pharmaceutical Intermediate for Antimicrobial API SynthesisThis oxazole derivative plays a targeted role in the synthesis of select active pharmaceutical ingredients (APIs), particularly for antimicrobial agents that require heterocyclic moieties in their core structures. Process chemists use the molecule within stage-wise condensation or coupling steps, integrating it for ring system modification while working under cGMP environments. Due to the specific reactivity of its oxazole ring, end users achieve efficient input-to-yield ratios and precisely control side product formation via validated process controls. Industry compliance standards
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2. Fine Chemical Intermediate in Agrochemical SynthesisLarge-scale agrochemical manufacturers utilize this compound in the construction of substituted phenyl-oxazole scaffolds for selective herbicides and fungicides. Chemists rely on its unimolecular synthetic applicability to ensure high selectivity towards desired pesticide precursors. Rigorous raw material input control, validated batch records, and impurity tracking form part of integrated quality management throughout the formulation process, aligning with environmental and safety regulations under global crop protection standards. Industry compliance standards
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3. Specialty Polymer Modifier in High-Performance ResinsIn polymer chemistry, manufacturers leverage this oxazole derivative as a chain-modifying agent or crosslinkable monomer within specialty resins, thermosets, and engineering plastics. Its selective alcohol and heterocyclic functionality facilitates controlled copolymerization and post-cure modification, often improving material dimensional stability, solvent resistance, or flame retardancy. Formulation scientists strictly monitor input ratios and reaction progress using FTIR and GPC analysis to meet stringent end-use requirements for regulated electronics and transportation markets. Industry compliance standards
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4. Research-Grade Building Block for Heterocyclic Compound LibrariesSpecialty chemical companies and research organizations employ 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol for combinatorial and medicinal chemistry projects. In route scouting for drug discovery or material innovation, chemists utilize its functional groups for rapid, modular assembly of heterocyclic compound libraries. Detailed weighing, stoichiometric control, and LC-MS assessments ensure reproducibility and sample integrity in all early-phase research syntheses. Documentation follows specific laboratory research quality guidelines and traceability systems. Industry compliance standards
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In the landscape of advanced specialty chemicals, 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol stands out for several reasons that become clear after years of hands-on production and regular engagement with industrial chemists. Coming off the line, this compound exhibits unique traits compared to standard oxazol derivatives, and those differences start with its chemistry and molecular structure, right on through to its handling and end-use performance.
Our chemists always pay close attention to detail in each production batch. The material maintains measurable consistency in purity and particle characteristics that matter during synthesis. Finished lots present as off-white to pale yellow solids, which helps technicians avoid the visual ambiguity that sometimes comes with similar heterocyclic compounds. Our typical purity specification remains at a minimum of 98%, subject to rigorous verification using HPLC and NMR. You won't find residual solvents, problematic byproducts, or abnormal water content in finished product that comes out of our reactors. Instead, the lot certificate tracks measurable critical content—actuals, not only limits. Moisture stays below 0.5%, as measured on each batch, meeting expectations for both research and plant-scale settings.
All product containers use robust HDPE drums or custom-sealed aluminum foil bags, depending on quantity and usage patterns. That choice isn’t arbitrary: we found over the years that minimizing exposure to ambient air and light preserves physical integrity far better than standard clear packaging solutions. Each lot follows the same documented route from reactor vessel through filtration, controlled drying, and triple-tested blending—reducing the batch-to-batch variability that could compromise downstream results. For shipment, product labeling reflects actual analytic data, not just typical values. Long-term customers have told us that this extra care resolves questions during their raw materials audits. Our controls don’t stop post-shipping; we keep retain samples—proving useful during customer qualification runs or if process questions ever come back down the line.
2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol sees growing adoption for specific synthetic organic chemistry projects, both at research and commercial development levels. Many start with its attractive role as an intermediate in medicinal chemistry, especially in custom syntheses where that oxazole core delivers desired electronic and steric properties. In our production planning meetings, we’ve learned from pharmaceutical chemists that the precise combination of a phenyl substituent and a hydroxyethyl side chain adds new reactivity options and opens up scaffolds for further derivatization. Compared with alternatives, this molecule brings more opportunities for targeted molecular modification, and that can shave weeks off lead optimization cycles.
Polymer chemists use the compound as a monomeric unit in step-growth polymerizations, targeting segments that demand both stability under thermal stress and select secondary functionalization. Through direct feedback, these users have highlighted improved chain propagation when compared to oxazole analogs lacking the 5-methyl substitution. Adding the additional aromatic character from the 2-phenyl position delivers further performance benefits in both high-strength and specialty functional plastics. Many times, teams engaged in electronic material research have looked for this particular ethanol-functionalized oxazole when pursuing finely tuned dielectric or photoreactive properties—traits not matched by standard linear glycols or other heterocycles.
On top of its primary uses, a few forward-thinking groups have come up with ways to repurpose this molecule within ligand systems for homogeneous catalysis, or as a valuable starting substrate in asymmetric synthesis sequences. Our technical team exchanged several in-depth notes with these researchers about practical reaction setups, preferred base reagents, and solvent selection. Through it all, the user stories point back to one fact: the detailed structural features embedded in the compound’s backbone create reliable chemical handles for both large and small molecule targets.
Experiencing the actual manufacturing floor shows that not all heterocyclic compounds behave the same, even when the core ring system looks similar on paper. Plenty of customers first begin with general oxazoles or their chloro-, methoxy-, or simple alkyl-substituted cousins. It only takes a few development cycles before the conversation circles around to yield reproducibility, purity drift, or unexpected side reactivity—especially on scale-up from lab glassware to kilo-lots. Our process has shown that the additional methyl group at the 5-position and the distinct phenyl ring confer different reactivity under basic and acidic conditions, controlling side-product formation much more effectively than unsubstituted analogs.
Standard precursors like 2-phenyl-1,3-oxazole or unsubstituted oxazol-4-ylethanol can offer lower synthetic cost and ease of availability, but our own batch records reveal a faster drop in shelf stability and an increased tendency for oxidative decomposition. Over many production campaigns, we’ve measured these changes in real time using both chromatographic and spectroscopic methods. Specific substitution changes more than the molecule’s paper properties—it shifts real-world handling, storage, and performance under process stress. Not every application benefits from the extra molecular complexity of this compound, but once a project requires a tightly defined chemical behavior—whether under aggressive heating, multi-step transformations, or long-term storage—the differences become tangible.
Each order leaves our facility backed by more than just a headliner specification. We track and analyze every run from raw material intake, through each synthetic stage, to completed lot. Analysis is not only for compliance, but also ensures that any feedback from the user community—a missed reaction endpoint, a lower than expected yield, variance in spectral data—can be quickly traced and remediated with real data in hand. We’ve seen this close connectivity prevent avoidable downtime for several partners during new product launches. The strong technical relationship between our chemists and customer process teams forms the backbone of long-term collaboration. Being the actual manufacturer fosters a sense of responsibility beyond product handoff, and we take pride in helping unravel atypical results or assist with process optimization.
Sourcing specialty chemicals isn’t just about the catalog listing or the quoted purity. Batch-to-batch continuity gives compound development a major boost because repeated effort doesn’t get lost fighting material variance. Regular users report smoother scale-up and minimized surprises on recrystallization or downstream purification. We routinely ship both small research lots and multi-kilo commercial runs from the same validated process and equipment, making it possible for clients to transition projects without re-qualification. Our systems were built for continuity. This practical experience informs how we approach both efficiency and risk in contract supply agreements.
Technical support goes much further than supplying a document packet. Our team fields questions on both process adaptation and troubleshooting, with the insight coming directly from those who built and ran the actual process. The value comes from hard-earned process knowledge—down to handling tips, preferred solvent choices, and thermal cycling constraints. End-users tell us they’d rather consult with an experienced practitioner than search through abstract technical notes that rarely match their real problems.
Several years on the production side have shown us that effective risk management starts well before a molecule reaches the user’s bench. This particular compound benefits from moderate stability, but storage conditions do influence the physical consistency and reactivity. We store all outgoing lots in sealed containers at ambient to slightly below ambient temperatures, protected from direct light. Thanks to regular shelf-life studies, each shipment comes with a clear production date and recommended usage window based on actual stability data, not just theoretical estimates.
During handling, we recommend standard PPE—gloves, goggles, and lab coats—as well as solid lab ventilation practices. This isn’t only about regulatory requirements, but also about feedback from workers who routinely measure and transfer powder or concentrate. On-site safety reviews with frequent users underline the importance of careful micro-scale weighing and minimal exposure to open air during transfers. Over time, these simple operational measures reduce risk for both seasoned staff and those new to heterocyclic chemistry.
Our facility maintains emergency practices in alignment with chemical safety standards. Technical data support for hazardous waste management accompanies bulk orders, reflecting actual recovery and disposal experiences from our own plant. Site audits highlight the benefit of robust documentation and straightforward access to critical information at the point of use.
It’s easy to appreciate the benefits of 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol after seeing it contribute to successful new molecule launches and improved scale-up conversion. Pharmaceutical teams frequently confirm improved selectivity in their target syntheses, especially in cases where alternative oxazoles failed to deliver reproducible results. Process troubleshooters note more predictable workup, less purification hassle, and recovery rates that align with paper targets. We see these outcomes reflected in recurring orders and an ongoing dialog around process improvements.
Some polymer customers discuss the compound’s contribution to better cross-linking performance and enhanced durability in specialized coatings. Reports from material scientists point out the direct correlation between this compound’s structure and measurable gains in dielectric performance or photoreactivity. The compound’s impact shows up both in enhanced functional properties and in practical metrics like production yield, process safety, and long-term storage stability.
Feedback isn’t limited to positive notes. Over the years, we’ve fielded tough questions on optimization, adjusted process strategy for unexpected side reactions, and explored alternate purification routes when a conventional approach fell short. Those conversations drive us to improve, rethink existing flows, and adapt facility controls—steps not always visible from the outside but essential for long-term reliability and user satisfaction.
The journey doesn’t end with a finished shipment. Regular process reviews aim at identifying incremental gains in purity, yield, and reliability. Insights into green chemistry inform solvent selection and waste minimization: manufacturing teams revisit these every production quarter. Over the last few years, we’ve adopted continuous improvement frameworks that actually reflect lessons from failed runs, not just successful ones. Experienced plant operators and R&D chemists draw real value from post-mortem analyses, which shape next-generation process pathways.
We foster ongoing partnerships with customer R&D groups, regularly brainstorming new application ideas for 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol. Some of the most creative breakthroughs result from direct conversations—projects that span from catalysis support to new building blocks for bioactive compounds. Any new findings get folded back into our data records, improving not just our internal knowledge base but also the support we offer to the wider chemical community.
Supply chain security remains a focus area, too. By controlling raw material sourcing and retention, we maintain steady output through supply challenges that periodically ripple through the industry. In practice, that has meant less schedule disruption for clients and faster qualification for those scaling from pilot to full plant. Experience on the manufacturing side teaches us to address issues before they become production slowdowns, sparing our customers from unnecessary risk.
Dedicated manufacturing offers more than just consistency—it empowers us to advocate for responsible chemical stewardship at every stage, from material development to end-use. We strive for a transparent, technically sound partnership with every user of 2-(5-Methyl-2-Phenyl-1,3-Oxazol-4-Yl)Ethan-1-ol. Reliable supply means more than filling an order—our job doesn’t end until the compound performs as expected in your process.
Feedback, whether from experienced development chemists or first-time users, drives us to revisit and enhance every aspect of design, manufacture, and support. That dedication defines real expertise in specialty chemical production. As a direct manufacturer engaged with expert users, we invite those new to this compound—and those who have worked with it for years—to reach out, share their experiences, and continue driving innovation together.