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2,5-Diphenyl-P-Benzoquinone

    • Product Name 2,5-Diphenyl-P-Benzoquinone
    • Einecs 202-085-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    Specifications

    HS Code

    921086

    Chemical Name 2,5-Diphenyl-p-benzoquinone
    Cas Number 700-13-0
    Molecular Formula C18H12O2
    Molecular Weight 260.29 g/mol
    Appearance Yellow crystalline powder
    Melting Point 170-173 °C
    Solubility Slightly soluble in water, soluble in organic solvents
    Inchi InChI=1S/C18H12O2/c1-3-9-15(7-1)17-13(19)11-12(10-16(17)8-2-4)14(20)18(9)5-6-8/h1-12H
    Smiles C1=CC=C(C=C1)C2=C(C3=CC=CC=C3C4=C(C2=O)C=CC=C4)O
    Pubchem Cid 13783

    As an accredited 2,5-Diphenyl-P-Benzoquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 25g amber glass bottle with a secure screw cap, labeled "2,5-Diphenyl-p-Benzoquinone, analytical grade, handle with care."
    Shipping 2,5-Diphenyl-p-benzoquinone is shipped in tightly sealed containers, protected from moisture and sunlight. It should be handled as a chemical substance, complying with local and international regulations. Proper labeling, cushioning, and packaging are used to prevent contamination or damage during transit. Appropriate documentation accompanies the shipment for safe and compliant delivery.
    Storage 2,5-Diphenyl-P-benzoquinone should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight and sources of ignition. Keep away from strong acids, bases, and oxidizing agents. Use appropriate personal protective equipment when handling, and store in a designated chemical storage cabinet compliant with local regulations.
    Application of 2,5-Diphenyl-P-Benzoquinone

    Applications of 2,5-Diphenyl-P-Benzoquinone in Industrial Manufacturing

    2,5-Diphenyl-P-Benzoquinone serves as a critical intermediate and reagent within several high-value chemical manufacturing domains. Its oxidizing properties and structural characteristics support precise transformations at scale, meeting the tight regulatory and process requirements of downstream sectors. Below are key industrial applications recognized in global downstream manufacturing.

    1. Organic Electronic Materials Synthesis

    Manufacturers of organic semiconductors regularly employ 2,5-diphenyl-p-benzoquinone during the synthesis of high-purity small molecules and polymers used for organic field-effect transistors and photovoltaic devices. It functions as a controlled oxidant, ensuring precise conversion of precursor compounds in multi-stage organic synthesis. Careful process control avoids over-oxidation or contamination, and continuous in-line monitoring assures batch consistency for large-scale electronic materials production.

    Industry compliance standards

    • IEC 62607 electronic materials test standards
    • ISO 9001:2015 certified quality management systems
    • REACH Regulation (EC) No 1907/2006 for reagent registration and safety
    • RoHS Directive 2011/65/EU for restricted hazardous substances

    Typical usage ratio

    • 0.5–2.0 molar equivalents relative to the targeted substrate, adjusted for batch reactor kinetics and substrate reactivity

    Downstream process integration

    • Phase-selective oxidation step during precursor conversion
    • Used in reaction vessels with nitrogen atmosphere to avoid unwanted reduction
    • Post-reaction purification involves solvent extraction and chromatographic steps
    • Analytical QC confirmation with HPLC and GC-MS at each synthesis phase

    Final product types

    • Organic photovoltaic (OPV) thin films
    • Organic light-emitting diode (OLED) active layers
    • P-type organic semiconductors
    • Electronic grade precursors for display technologies

    2. Specialty Dye and Pigment Production

    Chemical manufacturers utilize this benzoquinone derivative for the selective oxidation required in synthesizing high-performance dyes and pigments, particularly where fastness and chromatic purity are essential. Its role targets quinonoid transformation stages in anthraquinone and similar pigment structures, with batch parameters optimized for consistent yield and purity for industrial textile, plastics, and coatings segments.

    Industry compliance standards

    • ISO 18451-1 and 2 for pigment and dye classifications and methods of analysis
    • REACH Annex XVII restriction compliance for aromatic amines and impurities
    • OEKO-TEX Standard 100 chemical limits for textile applications
    • GMP guidelines as per EU Regulation (EC) No 2023/2006 for pigment production for food contact materials

    Typical usage ratio

    • 1–5% w/w relative to the dye precursor, modulated depending on batch size and color depth targets

    Downstream process integration

    • Introduced at controlled temperature in oxidation reactors post-condensation stage
    • Byproduct removal and adjustment via filtration and acid wash
    • Crystallization and drying steps downstream before pigment formulation
    • In-process testing for color index and residual oxidant levels

    Final product types

    • Anthraquinone dyes for polyester textiles
    • Organic pigments for automotive base coats
    • High stability colorants for industrial inks
    • FDA-compliant food contact colorants

    3. Pharmaceutical API Intermediate Manufacturing

    The strict oxidation characteristics of 2,5-diphenyl-p-benzoquinone make it an effective reagent for oxidation steps in active pharmaceutical ingredient (API) synthesis, particularly when constructing quinone, diketone, or nitrogen-containing heterocycle scaffolds. Its use supports precise control of chemical purity and process reproducibility, critical for compliance in regulated pharmaceutical manufacturing environments.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF (United States Pharmacopeia–National Formulary) standards
    • European Pharmacopoeia general chapters for process chemicals
    • FDA 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • 0.7–1.5 molar equivalents in oxidation steps of heterocyclic intermediates or ring closure reactions, tailored to target pathway yield and purity requirements

    Downstream process integration

    • Bathed into protected vessel after primary condensation for selective oxidation
    • Immediate neutralization and purification to prevent byproduct formation
    • Lab-scale validations before upscaling to multi-hundred kilo plant runs
    • Continuous process monitoring with validated analytical methods (HPLC, NMR)

    Final product types

    • API intermediates for anti-infective and oncology drugs
    • Heterocyclic building blocks for CNS-active molecules
    • Final stage antioxidants for specialty formulations
    • Pharmaceutical reference compounds

    4. Analytical and Research Reagent Supplies

    In analytical laboratories and specialty chemical R&D, 2,5-diphenyl-p-benzoquinone functions as a redox indicator and a synthetic reagent in determining reducing sugar content and metal ion detection. It provides controlled, selective redox changes in titrimetric and colorimetric assays. Reliability and consistent purity are vital due to the compound’s function in quantitative testing and reproducible research results.

    Industry compliance standards

    • ISO/IEC 17025 laboratory quality management
    • ASTM D1386 for test method guidance in colorimetric analysis
    • OECD Good Laboratory Practice (GLP) Principles
    • Chemical safety under GHS (Globally Harmonized System) guidelines

    Typical usage ratio

    • 0.1–2 g/L in buffer or solvent, depending on assay sensitivity and detection requirements

    Downstream process integration

    • Direct use in analytical titration for redox and sugar content determination
    • Stock solution or solid reagent dissolved before each run
    • Added at endpoint of specific chromatography or spectroscopic protocols
    • Washed and disposed according to laboratory waste management SOPs

    Final product types

    • Redox indicator reagent kits
    • Analytical standards for quality control labs
    • Diagnostic detection systems
    • Research chemistry toolkits
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    Certification & Compliance
    More Introduction

    2,5-Diphenyl-p-benzoquinone: Direct from a Chemical Manufacturer’s Floor

    Introducing Our Perspective on 2,5-Diphenyl-p-benzoquinone

    Producing 2,5-Diphenyl-p-benzoquinone never feels like just “turning out another chemical.” There’s a particular satisfaction when a batch comes off spec, bright, and reliable piece after piece — evidence of solid engineering, care in handling, and careful sourcing of inputs. Over years in this industry, we’ve seen demand for this compound rise and shift across different production scales. The needs of those buying this compound are wide and their reasons for choosing a manufacturer instead of a middleman boil down to trust and traceability.

    2,5-Diphenyl-p-benzoquinone is more than just another yellow crystalline solid with a fancy name. Chemists who know their materials understand its structure — with phenyl groups at the two and five positions on the benzoquinone ring — and use this to advantage. Whether it’s required as a reagent or as an intermediate, predictable performance and high purity eliminate a lot of downstream headaches. In each batch we manufacture, the focus stays on controlling moisture and byproduct levels. These aren’t theoretical concerns; left unchecked, impurity profiles and even minor traces of unreacted precursor material can throw off analytical results in end-use applications.

    What Drives the Need for Stringent Standards

    We get it: laboratory chemists, research institutions, and manufacturers need bench reagents that don’t mess with experimental reproducibility. At an industrial scale, those same needs scale up: no one wants rotten batches or contamination. Focusing on consistent particle size, color, moisture content, and trace metal contaminants, our own protocols came out of years spent troubleshooting for demanding clients in pharmaceuticals, analytical chemistry, and specialty polymers. If benzoquinones are manufactured with loose controls or blend stock is cut with off-spec batches, those end products start failing QC — something we work hard to avoid.

    A manufacturer’s process machinery, maintenance routines, and even logistics play a role here. Any deviation on the production line — air humidity, temperature spikes, filter issues, delays in crystallization — will show up in the final product. We pay as much attention to vessel cleaning and packaging materials as we do to synthetic routes and catalyst choices. This hands-on approach cuts down on customer complaints, keeps reputations solid, and, frankly, makes everyone’s life easier down the supply chain.

    Specifications that Matter

    Pure 2,5-Diphenyl-p-benzoquinone should show a distinct yellow coloration in the solid state, and this isn’t just for show — subtle shifts in hue can signal impurities. Over time, we’ve moved from relying just on melting point and TLC profiles to using HPLC and advanced spectroscopy. A typical batch will possess purity upwards of 99 percent, with moisture content carefully checked, since excess water content can slowly degrade quinone compounds during storage. Handling precautions focus mainly on keeping the solid dry and cool, using tightly sealed containers with inert liners to prevent both moisture uptake and incidental photodegradation.

    Particle size also finds its way into user discussions. Some chemists grind the crystals fine for rapid dissolution, but most labs appreciate a consistent, low-dust granular product that reduces loss during weighing and avoids static cling. Batch-to-batch repeatability relies on precise cooling rates and gentle mixing conditions in the final crystallization step. In our process, small tweaks and close monitoring allow us to offer repeatable results product after product.

    Comparisons to Other Benzoquinones and Substituted Variants

    Those who have worked with ordinary p-benzoquinone notice the difference straight away. Adding phenyl groups transforms not just the reactivity profile but also physical handling and safety. Unsubstituted p-benzoquinone fumes easily, gives off that sharp odor, and stains workspaces relentlessly. Our product, by comparison, has robustness and stability that reduce loss in transfer and make storage straightforward.

    In applications calling for steric bulk or altered reduction potentials, the diphenyl substitution delivers. Research chemists and process engineers leverage this for selective oxidations or as an electron acceptor in organic electronics. While standard p-benzoquinone exhibits a more aggressive redox profile, the 2,5-diphenyl version moderates that behavior. A small chemical tweak drastically changes how the compound participates in reactions, making it valuable for those designing syntheses or tuning reaction outcomes.

    Working as a direct manufacturer, we’ve fielded technical feedback on how competing materials — often of unknown or mixed provenance — cause problems down the line. Poorly purified 2,5-diphenyl-p-benzoquinone can contain colored by-products, which affect not just experimental outcomes but also analytical purity in pharma contexts. By controlling starting materials and process conditions, we consistently turn out a product that maintains the sharp yellow, manageable crystal profile, and high melting point that demanding users expect.

    Real-World Applications and Product Meaning

    It’s easy to spot the difference between commodity chemicals and those that customers remember and request. 2,5-Diphenyl-p-benzoquinone shows up in academic and industrial labs alike, with users applying it in oxidative coupling, organic synthesis, and polymer research. Each application expects a slightly different packing method or batch size, but all lean on reliability. Over the years, custom pack sizes and rapid batch reporting developed out of practical requests from consistent partners: those who want more than a catalog number and a hope that the label matches the contents.

    Power users in physical chemistry, electronics, and catalysis depend on reaction profiles. Here, variability is unforgivable; a poorly made batch can disrupt days or months of development, costing far more than the chemical itself. End-user feedback — sometimes gruff, always direct — shaped how we manage not just the synthetic route but also documentation, shipping timelines, and batch recall protocols. By hearing directly from buyers who deal with regulatory filings or who analyze trace-metals before running their experiments, we learn what matters in usage, not just on paper.

    Differentiators that Set Our Product Apart

    Comparing direct-from-manufacturer benzoquinone to commodity or resale batches, the experience lines up differently. Traceable sourcing, close network with raw input suppliers, and a clarity in batch documentation mean end-users trace back every drum or flask. We store date-of-manufacture records for every outgoing shipment, matching each lot to QC and analysis. These aren’t company secrets — they’re routine, built into SOPs because of seasoned feedback from regulatory and industrial chemists.

    In terms of actual product, removing fines and trimming oversized agglomerates produce a batch where every user can manipulate the powder or crystals without compounding losses. Saving users an extra step in processing counts for more than abstract “efficiency” — it keeps things working without unexpected delays or downtime. Raw material variance, left unchecked, threads through to finished product. Our laboratory techs document not just results but what happened on the shop floor, so that recurring issues can be traced to batches, not left floating in paperwork.

    Supporting Real Customer Needs: Lessons from the Floor

    What stands out isn’t just technical data, but habits developed scanning each batch with practiced eyes. If a batch suddenly comes up off-color, we know something’s shifted — either in a reagent supplier, a procedural variable, or an equipment hiccup. Training teams in the discipline of documentation and visual inspections, not just analytical passes, kept us ahead of persistent and frustrating contaminants that can creep into even well-vetted processes.

    Some of our clients remember the days when even modest laboratory orders brought wide swings in quality. Now, the dialogue focuses on delivery times, COA clarity, and matching physical parameters from lot to lot. We regularly field questions on trace residue content, solubility in different solvents, and secondary parameters like particle flow or ease of dissolution. Rather than hiding behind sales literature, we point to actual process documents showing what happens day-by-day. If a chemist calls about solubility or batch-to-batch differences, there’s someone in house who’s handled that product from synthesis to packaging, who knows the real issues.

    Handling, Packing, and Storage: More Than Logistics

    Maintaining 2,5-diphenyl-p-benzoquinone stability starts with picking the right packaging. In one phase of our history, switching from basic glass containers to lined, light-resistant flasks made clear differences in customer returns and physical appearance over time. Overhearing lab staff curse about clumped or degraded chemicals prompted us to cut out steps known to introduce moisture or dust. Using controlled environment rooms for packing, employing staff trained on chemical compatibility, and scheduling finished product dispatch within hours instead of days, real improvements took hold.

    Storing benzoquinone isn’t glamorous, but the troubles start early if not managed tightly. Picking polyethylene liners, using solid-seal lids, and labeling with batch histories, trace contaminants, and expiry projections reassures users facing regulatory scrutiny. Large-volume users, especially, expect stability through the entire shipment period, so our outbound QC runs focus not just on what’s inside the container, but on surviving the real-world shipping environment — temperature swings, vibration, and delays in customs.

    Why Direct Manufacturing Matters

    We often hear from clients burned by past experiences, where buying through several hands led to orphaned documentation, uncertain storage conditions or batch mixing from different sources. By manufacturing 2,5-diphenyl-p-benzoquinone in-house, every user can reach a responsible party who knows the batch, the process, and the background. There’s nobody passing the buck if questions arise.

    Sourcing matters as well. Skimping on precursor purity or accepting “special deals” from unknown upstream vendors never pays off. When the precursor batches shift quality, so does the final product — sometimes subtly, other times catastrophically. Controlling sourcing, vetting every raw input with our own analytics, and keeping updated vendor histories cut out these headaches. Those small cost savings at the front end often pale beside a single failed large-scale batch at a customer’s plant or negative results in sensitive downstream chemistry.

    Lived Experience: Challenges and Improvements in QA

    Improving quality controls for benzoquinones involved both setbacks and successes. Simply running standard analytical tests wasn’t enough; we had to investigate every failure, trace root causes, and adjust not just the synthetic parameters but the entire surrounding environment. Live batch monitoring, in-process sampling, and cross-training between chemists and floor techs cut out cryptic errors. These methods didn’t come from textbooks or external certifications but out of conversations with frustrated clients, returns, and internal reviews.

    The learning curve wasn’t gentle. Deciding which batch records to keep, which upstream complaints to address, and which technical improvements to invest in only became clear after rounds of missed deadlines or disappointing runs. Over time, building out redundancy and spot-checks became critical, even at increased operational cost. The outcome — a more reliable 2,5-diphenyl-p-benzoquinone — spread by word-of-mouth, not just catalogue listings.

    Supporting Regulatory Filers and Advanced Users

    End users in pharma and high-performance materials rarely accept “trust us” as an answer. Requests for detailed batch analysis, impurity profiles, certificate of analysis reports, and even specifics on packing environments come weekly. By preparing thorough documentation upfront, the dialogue stays technical, not defensive. Our lab supports external validation with sample sharing and technical Q&A, always returning to the basics: what went into this batch, who handled it, what checks did it pass, and what’s the documented shelf life.

    Specialty research institutions, in particular, care about even non-major impurities, recognizing their impact on results at the cutting edge of redox chemistry and analytical method development. Prepping batches for these clients involves double runs and sometimes custom modifications, and shipping inside specified time windows to maintain physical characteristics. From inquiry to shipment, the experience stays technical and direct, relying on facts proven on the production line and in lab notebooks.

    The Manufacturer’s Role Today

    Manufacturing 2,5-diphenyl-p-benzoquinone today is less about chasing volume than sustaining reputation and technical competence. Competing products flowing from traders and repackagers often claim the required purity on paper, yet skip the hard work of fielding complaints, investing in corrective systems, and maintaining technical support over time. For us, every outgoing lot closes a circle — from raw material, to process control, to customer application and eventual technical feedback.

    In this line of work, priorities align with doing basics right: clear communication, reliable planning, and solid technical backup. For those who rely on benzoquinone derivatives, these choices make a direct difference in daily chemistry, project milestones, and, sometimes, the bottom line of multimillion-dollar product launches or research programs. Working directly with real user requests, in partnership through unexpected challenges, remains the lasting advantage of manufacturing this compound firsthand — a difference felt not just in specs, but in the lived, real-world performance every batch brings.