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2,5-Dichlorohydroquinone

    • Product Name 2,5-Dichlorohydroquinone
    • Alias 2,5-Dichloro-1,4-benzenediol
    • Einecs 221-175-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    250540

    Cas Number 609-78-5
    Molecular Formula C6H4Cl2O2
    Molecular Weight 179.00 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 164-167°C
    Solubility In Water Slightly soluble
    Boiling Point Decomposes before boiling
    Density 1.65 g/cm³
    Synonyms 2,5-Dichloro-1,4-benzenediol
    Odor Odorless
    Pka Approximately 9.5
    Storage Temperature Store at room temperature, tightly closed
    Ec Number 210-201-2

    As an accredited 2,5-Dichlorohydroquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 2,5-Dichlorohydroquinone (25g) is a sealed amber glass bottle with a hazard-labeled, tamper-evident screw cap.
    Shipping 2,5-Dichlorohydroquinone is shipped as a solid, typically packaged in tightly sealed containers to protect against moisture and contamination. It must be labeled as a hazardous material, stored away from incompatible substances, and transported following regulations for corrosive or environmentally hazardous chemicals, ensuring safety for handlers and the environment during transit.
    Storage 2,5-Dichlorohydroquinone should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. The container must be tightly closed and protected from light and moisture. Use suitable, labeled containers made of materials compatible with the chemical to prevent degradation or accidental release. Store at temperatures recommended by the manufacturer.
    Application of 2,5-Dichlorohydroquinone

    Applications of 2,5-Dichlorohydroquinone in Industrial Manufacturing

    2,5-Dichlorohydroquinone is a functional specialty intermediate used across various segments of the chemical industry. This section details validated industrial downstream applications where this material serves a critical, differentiated function in synthesis, process formulation, and end-use product performance.

    1. Agrochemical Intermediate Synthesis

    Our material enters as a key intermediate in the production of selected herbicides and fungicides, where its unique substitution pattern supports targeted oxidation and halogenation reactions. Formulators use it during the construction of active moieties for triazole and anilide-based pesticides, ensuring precise molecular modifications that meet residue and stability requirements mandated by regulatory authorities. Compliance with permissible impurity levels defines the batch protocols, and product integrity relies on high purity lots, batch-to-batch reproducibility, and traceability.

    Industry compliance standards

    • REACH (1907/2006/EC) for supply within EU
    • FAO/WHO Specifications for Pesticide Products
    • ISO 9001:2015 Quality Management System
    • SANCO/3030/99 Residue Guidelines (EU)

    Typical usage ratio

    • 0.8%–3.2% of total agrochemical batch weight, tuned depending on target analog and desired purity

    Downstream process integration

    • Introduced at the condensation or acylation step for building heterocyclic rings in technical grade APIs
    • Subjected to further halogenation or oxidation post-coupling
    • QC checks for isomeric purity prior to final formulation blending

    Final product types

    • Triazole fungicides
    • Chlorinated anilide herbicides
    • Pre-emergence weed control agents
    • Intermediate actives for seed treatment products

    2. Dye and Pigment Manufacturing

    Manufacturers use 2,5-Dichlorohydroquinone in the synthesis of quinone-based vat dyes and advanced pigments. The compound ensures controlled electron density required for color stability and lightfastness in textile and polymer coloration. Proper handling limits chlorinated byproducts that can impact compliance, while targeted formulation achieves desired hue depth and solubility profiles for specialty applications in fiber and plastics industries.

    Industry compliance standards

    • Oeko-Tex® Standard 100 Annex 6
    • GHS/CLP Regulation (EC) No. 1272/2008
    • ZDHC MRSL Lists for input chemicals
    • ISO 14001:2015 Environmental Management

    Typical usage ratio

    • 3%–8% weight in dye precursor synthesis (adjusted per pigment chemotype and shade requirement)

    Downstream process integration

    • Enters as a nucleophile in oxidative coupling stage
    • Integrates with metal salt complexation (where required)
    • Chemical purity ensured before milling or spray drying into pigment forms

    Final product types

    • Vat dyes for cotton and cellulose
    • High-performance pigments for plastics and inks
    • Color concentrates for automotive coatings
    • Polymer-bound pigment dispersions

    3. Pharmaceutical Intermediate for Antibacterial Agents

    The compound functions as a starting raw material in the synthesis of specific hydroquinone-based antibacterial intermediates. Process engineers apply it in stepwise heterocyclic ring construction, exploiting its redox activity to anchor substituent groups in strict accordance with pharmacopeial requirements. Analysis for trace residuals and batch impurity profiles ensure compliance with finished dosage form registration and global supply chain safety.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) per ICH Q7
    • USP/NF and EP monographs, if applicable to end product
    • 21 CFR Part 211 (FDA Drug Quality Control)
    • Pharmaceutical Inspection Convention (PIC/S) Guidelines

    Typical usage ratio

    • 1.0%–2.0% mole ratio relative to primary amine reactant (batch calculated for synthetic route yield and impurity controls)

    Downstream process integration

    • Enters at the initial condensation or reduction step
    • Integrated within closed, solvent-controlled vessels to ensure minimum exposure
    • Monitored using HPLC and GC-MS for residual levels pre-purification

    Final product types

    • Intermediate for quinone-based antibacterials (external and topical formulations)
    • Raw material for selective oxidative coupling drugs
    • Synthetic precursors for anticancer investigational agents
    • Research chemicals for small molecule library screening

    4. Photographic Chemical Formulation

    2,5-Dichlorohydroquinone acts as a reducing agent in select black-and-white developer systems for industrial X-ray and lithographic applications. Its electron-rich para-dihydroxy structure ensures consistent reduction of silver halide grains under controlled alkaline processing conditions. Operators use it for applications where enhanced image stability, signal-to-noise ratio, and process reproducibility are critical for medical and industrial imaging.

    Industry compliance standards

    • ISO 18901:2020 for photographic film processing
    • ANSI/NAPM IT9.2 Safety and Handling in Imaging Applications
    • GHS Safety Data compliance for workplace control
    • RoHS restrictions for halogenated byproducts (if supplied within electronics sector)

    Typical usage ratio

    • 0.6–1.8 g/L in working photographic developer solution, adjusted to processing time and temperature

    Downstream process integration

    • Dispersed dry or as solution concentrate into aqueous alkaline developer bases
    • Stabilization via balancing with buffering and preservative agents
    • Blended immediately before use to maximize shelf life

    Final product types

    • X-ray film developers for medical imaging
    • Lithographic plate processing solutions
    • Photographic print developers for archival use
    • Industrial imaging system chemistry
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    Certification & Compliance
    More Introduction

    2,5-Dichlorohydroquinone: Bringing Consistent Performance to Modern Chemistry

    Understanding 2,5-Dichlorohydroquinone: More Than a Chemical Name

    At our facility, 2,5-Dichlorohydroquinone gets handled every day in the hands-on world of chemical synthesis. Its formula C6H4Cl2O2 underpins what sets it apart, but formula alone has little value without the trust that comes from a product meeting tough standards year after year. For those of us at the production line, measuring batch purity, drying materials, and controlling contamination risk are as real as the solid crystals piling up in the tanks. This is not about turning out a bag of powder and walking away. It's about holding a consistent structure across every kilogram, so that downstream clients—be they running synthesis for pharmaceutical intermediates, dye processing, or specialty polymers—don’t face surprises that cost them days or dollars.

    Our Specifications: Simple, Reliable, Tested

    We manufacture 2,5-Dichlorohydroquinone as a white to off-white crystalline powder. Typical batches register over 99% purity by HPLC, with chloride and sulfate levels kept below rigorous cutoffs. Our technicians measure moisture content daily, since even small variations can mean trouble when customers scale up in reactors. Packing differs between bulk and research-grade shipments, but vacuum-sealed linings and ventilated drums are standard for any shipment leaving the plant.

    The difference between published specification sheets floating around online and the powder one actually receives boils down to operational detail. Our chemists run melting point checks, monitor for trace metals, and archive retention samples for six months, in case questions come up. The scrupulous records and traceability matter: when a customer calls after three weeks regarding a subtle shift in yield, it’s the production logs and batch controls that solve the mystery, not sticker labels or a certificate PDF.

    How Our 2,5-Dichlorohydroquinone Performs in the Plant

    This molecule finds daily use in the lab and plant for more reasons than purity alone. In the manufacture of various pharmaceuticals, it often joins reaction streams where exacting oxidation states and functional group placements affect the whole synthesis. For example, when a pharma customer attempts to introduce a dichloro-moiety onto a p-benzoquinone ring, only precise starting material guarantees that yields don’t collapse or impurity profiles drift.

    In the field of dye manufacturing, our clients blend it with precursors to generate either bright pigments or specialty resins where light fastness cannot be left to chance. Here, it's not only the content but the shape and flow characteristics—narrow particle size range, reproducible solubility—that save time during milling and minimize dust generation. Color consistency downstream, an important point for textile and ink producers, rises directly from the controlled crystal forms leaving our reactors.

    Reliability Built from Experience

    Our background manufacturing chlorinated hydroquinones leaves us with plenty to say about raw material quality. Each year, dozens of solvent drums, abstracts, and tech bulletins cross our desks, all touting anhydrous conditions and advanced reactors. But in our work, the dependability of 2,5-Dichlorohydroquinone has more to do with the skills of our processing team and less to do with whatever fancy term makes its way onto a flyer.

    We learned early that 2,5-Dichlorohydroquinone acts as a canary in the chemical plant for metal contamination. Just a small leak from a line, or one skipped glassware wash, is enough to trigger downstream yellowing or batch rejection by finicky customers. Our response included tightening instrument calibration and training techs to spot off-spec crystals under a microscope. This hands-on vigilance beats any procedural change and pays back by reducing both returns and headaches.

    The Value of Quality: Beyond the Typical Offering

    Plenty of suppliers may promise material “meeting” some published standard, but real-world performance rides on much more than specification checkboxes. We learned from field experience that 2,5-Dichlorohydroquinone with broader melting point ranges, even at 98% purity, poses problems when sensitive downstream chemistries get involved. Unseen by simply looking at purity numbers are trace halide content, moisture pickup over transport, or the accidental inclusion of other isomers. Clients who shifted to our material, often after a round of failed syntheses with generic product, point out cleaner reaction profiles in HPLC traces and easier handling in large batch reactors.

    We design our process controls around these realities. Closed transfers, controlled atmosphere drying, and effective impurity purging step outside the boundaries of minimum compliance and address practical needs: less downtime, smoother filtration, fewer off-spec reactions. Our QA team works directly with downstream users to match the lot consistency to their analytical requirements, whether for small research batch or plant-scale continuous runs. This partnership mindset shows up in lower batch-to-batch variation than market average and deeper customer loyalty.

    Applications: Meeting Demands Across Industries

    Day-to-day, our 2,5-Dichlorohydroquinone lands not just in one sector but across a spectrum of demanding industries. Pharmaceutical intermediates depend on reliable functional groups for downstream coupling reactions and final product quality. Research labs, under pressure to chase new synthetic targets, rely on our lot consistency so that failures don’t arise from unpredictable variability. Many dye producers, constantly in search of more robust chromophores, use our material as a core building block to anchor their innovation—and profitability. The electronics sector, sometimes overlooked, values the stability and reactivity in niche applications including advanced battery electrolytes and polymer modification.

    In every case, usage patterns teach us how vital tight controls remain. For example, in a sulfonation reaction on the bench, slow and uneven dissolution from poor processing can stop a chemist’s work. In a continuous manufacturing setup where reactor time costs thousands an hour, even minor mismatches in particle distribution or solvent retention spell trouble. We support these demanding needs through collaboration with application chemists and real-time adjustments to production protocols when recurring customer feedback points to process limits.

    Production Scale and Capabilities

    We supply 2,5-Dichlorohydroquinone in quantities ranging from kilogram research packs to multi-ton lots for full-scale industrial campaigns. Our facility includes dedicated lines to separate chlorinated intermediates from sensitive organics, minimizing cross-contamination. Batch reactors, automated dosing systems, and on-site analytical labs reinforce quality at every stage—from raw material receipt, through production, to final shipment. Our QA department runs checks not just on chemistry but also on packaging and logistics, aiming to prevent small mishaps (moisture intrusion, mislabeling, transit delay) that cause big headaches after delivery.

    Scaling up from a single flask to a multi-ton line brought practical lessons in powder handling, storage management, and hazard mitigation. Moisture condensation, static discharge, and long-haul transport each require planning. For example, a seemingly minor change in barrel type once led to a shipment arriving with caked powder, prompting us to upgrade container linings across all lots. These details may sound mundane, but repeat customers often mention trouble-free handling as a key factor for sticking with our team.

    Differences That Set Us Apart

    Our 2,5-Dichlorohydroquinone stands apart from commodity alternatives in more ways than price. Purity alone does not define consistent performance. Instead, tight control over starting materials, validated synthetic pathways, and comprehensive in-process testing create a final product that supports high-yield reactions. Most off-the-shelf powders lack this degree of attention. For instance, our commitment to low-metal contamination eliminates sources of colored by-products in dye making, while others gloss over the impact this has on final tint or shelf life. We work with several long-term partners in pharmaceutical and electronics manufacturing who previously struggled with inconsistent conversion rates. Clients now note improved throughput and fewer purification steps when switching over to our material, reflecting the benefits of our meticulous approach to purity and processing.

    There are other chlorinated hydroquinones out there, boasting similar chemical structures. 2,6- and 2,3-isomers, for example, have distinct reactivities that render them unsuitable for specific downstream transformations. We ensure authentic, single-isomer material through both synthetic route design and post-synthesis analytical verification. This focus reduces off-target reactions and boosts process efficiency, directly supporting innovation in industries as diverse as pharmaceuticals and high-performance polymers.

    Challenges and Our Approach to Solving Them

    No chemical plant runs without occasional setbacks, especially when aiming for product improvements or higher efficiencies. With 2,5-Dichlorohydroquinone, the most common issues involve moisture absorption during storage, minor color changes on aging, and unplanned variability in crystal form in large batches. Each brought its own share of late-night troubleshooting and process audits. We responded by introducing new drying equipment, updating storage protocols, and running extended stability studies. Data from these studies guide our packaging choices and inform clients about what to expect over longer storage periods.

    Feedback from our users, particularly those scaling up new syntheses, shaped continuous improvements. For example, one customer found sporadic filtering difficulties with early-lot powder. A closer look traced the culprit to fines generated during subsequent grinding, which we now address with softer mills and in-line particle size monitoring. These operational changes don’t show up in generic datasheets but lead directly to easier downstream processing and smoother large-scale operations.

    Partnership Through Transparency

    Honest conversations about capabilities and shortcomings help sustain professional relationships. Unlike resellers or distributors, who must often rely on received information, our production engineers engage directly with end users to troubleshoot issues and discuss performance in context. When a batch doesn’t perform to expectations, our team reviews every stage, from sourcing raw chlorinated benzenes to the nature of catalysts used in each run. If a process deviation occurs, we open our logs so that chemists at customer facilities receive not just answers but the context to adjust their own downstream steps. In many industries, this level of transparency stands out as rare.

    We offer real-time support throughout the product lifecycle. If a scale-up run uncovers a challenge or a research chemist needs more detailed impurity profiles, our staff provides the supporting data. Retained samples from each production batch remain on hand for direct comparison. Regular training and open forums between plant, lab, and customer teams ensure both quick solutions and long-term process learning.

    Sustainable Manufacturing and Environmental Awareness

    Modern chemical manufacturing faces rising pressure to address environmental impacts. We see this reality both in evolving regulation and customer demand. Sourcing responsible raw materials, minimizing waste, and controlling effluent matter every bit as much as yield and throughput. In our experience, investing in closed-loop systems and efficient solvent recovery helps keep environmental impact in check, while also reducing operating costs.

    Each improvement in yield minimizes waste, so we design reactor charging and filtration procedures to leave as little behind as possible. Rather than accept small-scale chlorinated by-product formation as inevitable, we redirected efforts toward process optimization and secondary recovery. Recycled solvents undergo purification on-site, rather than shipment offsite or disposal—turning potential hazard into value.

    Setting Our Sights Forward

    The production of 2,5-Dichlorohydroquinone represents both tradition and progress in our manufacturing lineage. We consistently work to refine our process, not resting on regulatory minimums but aiming higher to serve partners who depend on robust chemical performance every time. Unlike secondary channels where brand and batch vary, our approach involves building product lineage and traceability as a matter of pride—not regulation. We test, adapt, and refine based on our first-hand shop floor observations as well as feedback from the labs and plants relying on our output.

    For clients needing reliable, process-ready 2,5-Dichlorohydroquinone, our continued investment in quality control, worker training, and equipment modernization makes the results tangible: reaction predictability, minimal downtime, and less time wasted fixing production glitches that shouldn’t have happened in the first place. We welcome honest feedback and stand ready to support our partners with the technology, expertise, and transparency that define the best of modern chemical manufacturing.