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2,5-Dichlorobenzyl Alcohol

    • Product Name 2,5-Dichlorobenzyl Alcohol
    • Alias Benzyl alcohol, 2,5-dichloro-
    • Einecs 219-086-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    541492

    Cas Number 1777-82-8
    Molecular Formula C7H6Cl2O
    Molecular Weight 177.03 g/mol
    Iupac Name 2,5-dichloro-1-(hydroxymethyl)benzene
    Appearance White crystalline solid
    Melting Point 64-66 °C
    Boiling Point 285.2 °C at 760 mmHg
    Density 1.37 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 127.5 °C
    Odor Characteristic mild aromatic
    Refractive Index 1.590
    Pubchem Cid 13176

    As an accredited 2,5-Dichlorobenzyl Alcohol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 grams, with screw cap. White chemical label displays: "2,5-Dichlorobenzyl Alcohol, CAS: 17752-84-6, Hazard warnings."
    Shipping 2,5-Dichlorobenzyl alcohol should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled and protected from light and moisture. Typically transported as a hazardous material, it requires compliance with DOT, IATA, or IMDG regulations, ensuring appropriate documentation, temperature control if necessary, and secure, upright placement to prevent leakage or accidental exposure during transit.
    Storage 2,5-Dichlorobenzyl alcohol should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Keep the container protected from light and moisture. Ensure proper labelling and restrict access to trained personnel only. Store at room temperature and follow all relevant safety and regulatory guidelines for chemical storage.
    Application of 2,5-Dichlorobenzyl Alcohol

    Applications of 2,5-Dichlorobenzyl Alcohol in Industrial Manufacturing

    As an established producer, we supply 2,5-Dichlorobenzyl Alcohol for use in specialized industrial sectors. Below, we outline the primary downstream applications, including regulatory requirements, recommended usage levels, process steps, and finished product categories.

    1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredients (APIs)

    Pharmaceutical manufacturers utilize 2,5-dichlorobenzyl alcohol as a key intermediate in the synthesis of various drug molecules, especially for antimicrobial agents and APIs with substituted phenyl structures. Our material supports strict quality metrics for inclusion in multi-step organic synthesis lines, employing it primarily in the early condensation and protection stages. Downstream partners control the alcohol’s purity profile to prevent residual process impurities and to ensure compliance for medicinal use in regulated markets.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) guidelines (21 CFR Parts 210/211, US FDA, EU GMP)
    • International Council for Harmonisation Q7 (ICH Q7) for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) and United States Pharmacopeia (USP) as referenced in API registration dossiers
    • REACH registration for raw material sourcing and handling (EC No. 1907/2006)

    Typical usage ratio

    • Used at 5-15% molar ratio relative to final API target, with range adjusted based on specific synthesis route and yield optimization.

    Downstream process integration

    • Charged into initial reaction vessels as a substrate for etherification, acylation, or as a protecting group agent before downstream purification and final compound assembly steps.

    Final product types

    • Antimicrobial drug substances
    • Intermediates for respiratory tract medication APIs
    • Benzyl-substituted pharmaceutical actives
    • End-use finished dose medicines

    2. Antiseptic and Disinfectant Formulations

    Producers of hospital-grade antiseptics incorporate 2,5-dichlorobenzyl alcohol due to its established bacteriostatic and fungistatic characteristics. Technical teams formulate it alongside other active agents in concentrated sanitizing fluids and oral hygiene products. The chemical’s purity, solubility, and residual toxicology play critical roles in compliance with health and safety performance requirements for topical or mucosal applications.

    Industry compliance standards

    • European Chemicals Agency (ECHA) Biocidal Products Regulation (BPR, Regulation EU No 528/2012)
    • US Environmental Protection Agency (EPA) disinfectant registration guidelines (FIFRA regulations)
    • ISO 13485 Quality Management for Medical Devices (where applicable in finished products)
    • Local Ministry of Health approvals (e.g., China National Medical Products Administration - NMPA for disinfectant actives)

    Typical usage ratio

    • Incorporated at 0.2-1.5% w/w in topical antiseptic liquids; up to 2% w/w in oral rinse blends, subject to product type and national maximum residue restrictions.

    Downstream process integration

    • Dosed as a pre-mixed solution or directly blended with carrier solvents during formulation; followed by filtration, pH adjustment, and microbial testing before packaging.

    Final product types

    • Hand sanitizers
    • Mouthwashes
    • Medical surface disinfectant sprays
    • Antiseptic lozenges

    3. Agrochemical Intermediate for Fungicide Synthesis

    Agrochemical manufacturers employ 2,5-dichlorobenzyl alcohol in the preparation of phenyl-substituted fungicide actives targeting crop protection markets. Syntheses often utilize the alcohol in nucleophilic substitution reactions, constructing key intermediates prior to heterocyclic ring closure. Regulatory controls strictly govern residual levels in technical material and derived actives, with compliance monitored through documented certificates of analysis and traceability protocols.

    Industry compliance standards

    • Food and Agriculture Organization (FAO) and World Health Organization (WHO) Specifications for Plant Protection Products
    • OECD Good Laboratory Practice (GLP) standards for active ingredient testing
    • EU Regulation (EC) No 1107/2009 on the placing of plant protection products on the market
    • ISO 9001 quality system management in agrochemical manufacturing

    Typical usage ratio

    • Utilized at 6-12% molar ratio per batch yield requirement for core fungicide intermediate; actual rate tailored to target molecular weight and synthesis conversion factors.

    Downstream process integration

    • Added to organic synthesis reactors for stepwise formation of benzyl-containing scaffolds; intermediate stream processed further for formulation or granulation of commercial actives.

    Final product types

    • Foliar fungicides
    • Seed treatment agents
    • Crop protection technical concentrates
    • Finished granular or suspension concentrate pesticide formulations

    4. Chemical Building Block for Specialty Polymer Additives

    Material science and polymer manufacturers integrate 2,5-dichlorobenzyl alcohol as a functional building block in polymer manufacturing, especially to synthesize benzyl-substituted crosslinking agents or chain modifiers. Its defined substitution profile impacts polymer characteristics such as chemical resistance and thermal stability. Quality teams verify trace impurities and control residual monomer profiles to meet performance specifications in the final compounded materials for industrial markets.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems for manufacturing facilities
    • REACH Annex XVII for substances in articles (EC No. 1907/2006) regarding chemical handling and downstream notification
    • ASTM International Standards for Polymer Additives (e.g., ASTM D6247, ASTM D256)
    • RoHS (Restriction of Hazardous Substances) Directive 2011/65/EU for end-use electronics polymers

    Typical usage ratio

    • Formulated at 1-8 parts per hundred resin (phr) based on desired polymer properties and crosslinking density; dosage governed by polymer chemistry and downstream product application.

    Downstream process integration

    • Integrated during pre-polymerization or reactive extrusion stages, where the raw material acts as a chain stopper or reactive diluent; followed by compound blending and pelletizing.

    Final product types

    • Epoxy resin modifiers
    • Engineering thermoplastics
    • Electronics encapsulants
    • UV-curable industrial coatings
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    Certification & Compliance
    More Introduction

    Introducing 2,5-Dichlorobenzyl Alcohol: Our Manufacturing Perspective

    Setting the Stage for Quality: Hands-On Experience with 2,5-Dichlorobenzyl Alcohol

    There’s a lot of noise on the market, especially when it comes to specialty chemicals like 2,5-Dichlorobenzyl Alcohol. As the manufacturer, we work directly at the core—handling raw materials, controlling reactions, and pushing for consistency. We don’t rely on generic descriptions; we stand inside the reactor room, watch the temperature curves rise, and test every batch as it flows off the line. Here the conversation moves beyond paper specs. Every parameter— from purity to moisture level and melting point—reflects decisions made by skilled operators, repeated quality checks, and tried-and-true process adjustments. We aim for a purity above 99%, and we track impurities that most buyers never see just to secure long-term reliability for downstream applications.

    Our daily work proves one thing— 2,5-Dichlorobenzyl Alcohol isn’t just another chemical in a warehouse. In the pharmaceutical sector, a stable and reliable intermediate makes the difference between a successful pilot and a batch recall. Beyond pharma, daily reliability means fewer surprises for agricultural and coating producers who know that shifting between production lots can throw off reaction progress, physical appearance, or even shelf life. Our product keeps those concerns in check.

    The Substance Itself: Getting to Know 2,5-Dichlorobenzyl Alcohol

    Each sample starts as off-white crystalline powder with minimal residual solvent or particulate matter, hosting a molecular formula of C7H6Cl2O. We watch not only for the stated chemical but for subtle indicators like odor, transparency, and crystal habit. These offer clues to process issues even spectrometers might miss. We weigh our technical grade and pharmaceutical grade differently. Technical grade finds greater use in agricultural formulation, coating intermediates, and industrial antimicrobials, whereas pharmaceutical grade undergoes extra refining steps, including rigorous filtration, multiple crystallization phases, and batch-by-batch analytical review.

    As a direct manufacturer, we work closely with synthesis teams who depend on reliability batch after batch. That dedication translates into tight melting range control, usually at 74-78°C, and minimal hydrolysis by-products. Products that don’t meet our thresholds get recycled or reprocessed, not repackaged and shipped off to another buyer. With laboratory and process controls monitored by team members with years on the floor, we know exactly how every drum is made and who oversaw its quality at origin.

    Understanding the Practical Difference

    Where pure specification sheets end, real-world differences show up. The market often sees benzyl alcohols lumped together—simple benzyl alcohol, p-chlorobenzyl alcohol, 2,4-dichlorobenzyl alcohol, and 2,5-dichlorobenzyl alcohol—yet each serves different requirements. In antimicrobials, 2,5-Dichlorobenzyl Alcohol brings a unique double-chloro substitution pattern that changes both its solvent compatibility and its efficacy against certain pathogens. In pharmaceutical manufacture, it enters at critical points where alternate substitutions either trigger regulatory hurdles or present solubility problems. Own experience has shown certain resin formulations only work with specific isomers. Swapping just one chlorine can turn a smooth-curing varnish into one riddled with cloudiness or tack.

    Customers who have used our 2,5-Dichlorobenzyl Alcohol for years bring us feedback that reinforces what lab data already makes clear. Substitution with 2,4-dichloro or single-chlorinated benzyl alcohols rarely mimics the performance profile required for their end-uses. We see clear demand for high-purity 2,5-Dichlorobenzyl Alcohol in flavors and fragrances too—the double chlorine configuration introduces a sharper, distinctive note, used in trace amounts to stabilize complex formulations. Industry end-users know that simple substitutions rarely suffice. We have spent years refining processes to avoid trace phenolic or aldehyde impurities that can throw flavor or reactivity off-kilter.

    Why Our Approach Matters: Manufacturing with Application in Mind

    We walk the plant floor and maintain close dialogue with R&D partners, which means that manufacturing decisions respond to new challenges as they arise. If a coating customer sees a color shift, we look for root causes—starting from raw material procurement and moving through every phase of distillation and filtration—before that drum ever leaves the warehouse. We avoid certain common solvents that risk residuals, and we check by GC for trace impurities that can otherwise fly under the radar. Process water’s purity, impeller cleaning frequency, and even ambient plant humidity affect both consistency and shelf stability.

    We have seen upstart entrants race to the bottom, offering so-called 2,5-Dichlorobenzyl Alcohol at a lower price. Plant tours or customer field tests often reveal these batches hold more water, residual solvents, or color bodies, which surface during real-scale syntheses, and result in wasted time and cash downstream. Our team members track not just lot yields but the exact temperature and pressure curves for each reactor run. We validate each run using reference standard comparisons, keeping archived samples from every batch for retrospection. Our labs run real production samples by HPLC and NMR to spot outliers before they inconvenience anyone in the field.

    Product reliability starts upstream. Sourcing raw dichlorotoluenes from proven suppliers gives us leverage to enforce our own spec demands. We don’t just “buy from the market.” We personally audit key suppliers and keep in close contact, understanding factors from their storage practices to delivery turnarounds, which is how we mitigate downstream variability long before it could ever touch the finished material.

    How Our 2,5-Dichlorobenzyl Alcohol Finds Use

    People who work with chemicals at scale develop a sense of where each compound will shine. Our 2,5-Dichlorobenzyl Alcohol heads to active pharmaceutical intermediate manufacture, where it acts as a key building block in antimicrobials, expectorants, and other APIs. Its reactivity with acid chlorides can be tuned for esterification, making it suited for creating specific benzoates and acetates.

    Clients in the coatings field look for tight spec controls— a consistent melting point, fine crystalline structure, and a reliable absence of color bodies—knowing that even slight variations can knock an entire batch out of specification. Pesticide developers specify 2,5-Dichlorobenzyl Alcohol when they need a stable carrier molecule that supports slow release and consistent dispersal. Fine chemical and aroma houses rely on its unique substitution pattern to anchor formulations with both chemical stability and a traceable, recognizable olfactory quality.

    We’ve taken calls from process engineers who faced repeat issues using lower-grade alternatives. A residue stuck in heat exchangers, crystal deposits forming during summer storage, or off-odors surfacing during compounding—these point back to overlooked impurities or the wrong isomer. Our customer support connects those operators directly to our technical team, so that resolutions happen at the source, well before finished goods land in end-users’ hands.

    Differences from Other Benzyl Alcohols—Originating from Chemistry, Proven by Application

    Many only notice the full impact once batches start running side by side. Simple benzyl alcohol, with its lone hydroxymethyl group and no further ring substitutions, behaves differently in oxidative environments or acidic condensations. Replace just one hydrogen with a chlorine and the physical properties shift: melting point rises, solvent resistance strengthens, and metabolite paths fork. Jump to 2,4- or 2,6-dichloro isomers and downstream behavior changes again.

    We’ve run controlled side-by-side comparisons in our R&D cell. 2,5-Dichlorobenzyl Alcohol shows better thermal stability and a cleaner conversion path in certain Grignard reactions, particularly where isomeric purity matters. Where off-quality benzyl alcohols introduce colored by-products in acrylic resin synthesis, our material helps keep finished product close to transparent. These distinctions matter not in slideshows but in real plants where a failed batch means days of lost production, environmental compliance headaches, and blown deadlines.

    A less-discussed detail relates to downstream waste treatment. Some localities have strict residual limits, and the impurities in poorly produced batches can provoke costly surcharges or even regulatory intervention. High-purity 2,5-Dichlorobenzyl Alcohol from tightly controlled sources means easier compliance, less spent on reprocessing, and waste streams handled without last-minute surprises.

    How We Make Every Batch Count

    We’ve built our production lines over years of troubleshooting and process iteration. Reactor designs, agitation schemes, and thermal transfer systems have all been tuned for the singular demands of dichlorinated intermediates. Double-sealed containment prevents cross-contamination, and our transfer lines undergo regular flushing. We calibrate every analytical instrument against certified reference materials and invest continuously in staff training, so that plant technicians grow familiar with not only machinery but also the finer points of product behavior across temperature and humidity ranges.

    Years ago, a persistent trace impurity in one campaign forced us to backtrack several steps—tracing each resin coating, filter, and additive back to its source. Rather than cut corners, we reconstructed entire cleaning protocols, swapped gasket materials, and revalidated all storage vessels. These details rarely reach purchasing agents, yet they mean that drums and bags delivered now show consistent analysis on each certificate. Most importantly, fewer surprises appear in customers’ research chemistries, pilot runs, or full-scale operations.

    Batch-wise, we blend hands-on analytical testing—using chromatography, Karl Fischer water titration, melting point comparison, and sometimes even scanning electron microscopy—with automated in-process monitoring. Human oversight catches complexities that software or sensors alone cannot. We routinely hold finished material for extended stability testing, building a database of material behavior under multiple real-world storage and handling conditions.

    Supporting Users—On the Ground, Where It Matters

    We recognize that the real world brings curveballs. Weather, shipment delays, and evolving end-use requirements all demand flexibility. Beyond shipping drums, we provide guidance on best storage conditions, optimal pre-mixing protocols, and common pitfalls in upstream handling. We’ve visited partner facilities, witnessed unique challenges, and modified packaging—sometimes switching to smaller containers or upgraded liners—to help clients work with our 2,5-Dichlorobenzyl Alcohol in novel ways.

    As manufacturing partners, we consult directly with process engineers, chemists, and operations staff. Sometimes this means rerunning analyses to solve a puzzling process upset; other times, walking customers through subtle differences in how volatile impurities can impact a downstream reaction. Our technical reports don’t just include numbers; they include observations, photos, and practical notes. We want users to see us as an extension of their own team—pushing not just for maximum product quality but for hands-on, workable advice.

    We see production not as a closed loop but as a collaborative effort spanning best practices and shared know-how. Over the years, we’ve built a feedback loop—listening, troubleshooting, and innovating in response to what customers face after our product reaches their hands. This dialogue improves our actions, from raw material selection to final shipping and support.

    The Role of Traceability and Transparency

    Traceability isn’t a bureaucratic buzzword for us—it’s a practical tool. We archive exhaustive records for every run, down to timestamps on vessel charges, filtration schedules, and labeling history. On audit, we open our doors to customer quality teams. We avoid jargon and provide points of contact familiar with every upstream and downstream touchpoint. Our willingness to be transparent builds trust and allows us to respond rapidly if questions—on quality, trace residue, or compliance—surface long after delivery.

    We also carry out backward and forward tracing, so any raw material concern triggers proactive outreach to customers that may be affected. This is rare, but our history proves it can save many from unnecessary trouble or costly recalls. Our drive for traceability stems from years spent handling the realities of chemical supply—real costs, regulatory scrutiny, and above all, responsibility for safe, predictable results in every downstream use.

    Responsibility Beyond the Chemical: Environmental and Regulatory Commitment

    Manufacturing specialty chemicals calls not just for technical strength but heightened attention to safety, environmental impact, and evolving regulation. For us, responsible production aligns with how we manage process emissions. We use closed loops and condensers to keep fugitive emissions far below required limits and regularly review our solvent recovery and waste reduction measures. Wastewater and solid by-products aren’t someone else’s problem—they get managed with documented procedures, often exceeding baseline regulatory standards. Staff receive ongoing compliance training so that every process improvement factors in not only productivity but also sustainability and environmental protection.

    Our material consistently fits within the purity and quality requirements needed for use in regulated pharmaceutical and agricultural sectors, and we stay ahead of changing laws by keeping our technical files up to date with the latest standards. Our compliance team conducts regular reviews and keeps a line open for end-users who might face similar regulatory questions in their own regions.

    Looking Forward—Supporting Progress, Driving Reliability

    We believe that reliability moves industry forward. As a manufacturer, we learn something new every campaign. Customer feedback, new application fields, and the constant left-field challenges of scale-up keep us honest and foster our drive for quality. 2,5-Dichlorobenzyl Alcohol will continue evolving—from a crucial API intermediate to broader applications in materials and specialty formulations. Our task is to keep refining both chemistry and service so users receive not just a product, but comprehensive support for success.

    We recognize no one solution fits all. Our door stays open to collaboration, to feedback, and to the continual advancement that stems from hands-on experience, accountability, and investment in both people and process. At every stage, from first inquiry to production and delivery, we blend expertise with transparency and a willingness to roll up our sleeves until problems are solved and new opportunities found. That’s the manufacturer’s difference, and it marks every drum, every lot, and every partnership we form.