Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2,5-Dichlorobenzene-1,4-Diamine

    • Product Name 2,5-Dichlorobenzene-1,4-Diamine
    • Alias para-Phenylenediamine-2,5-dichloro
    • Einecs 202-457-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    999504

    Chemical Name 2,5-Dichlorobenzene-1,4-diamine
    Molecular Formula C6H6Cl2N2
    Molecular Weight 177.04 g/mol
    Cas Number 20103-09-7
    Appearance Off-white to light brown crystalline powder
    Melting Point 218-221 °C
    Solubility In Water Slightly soluble
    Density 1.44 g/cm³ (approximate)
    Synonyms 2,5-Dichloro-p-phenylenediamine
    Structure ClC6H2(NH2)2Cl (chlorine at positions 2 and 5, amino at 1 and 4)

    As an accredited 2,5-Dichlorobenzene-1,4-Diamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed plastic bottle labeled "2,5-Dichlorobenzene-1,4-Diamine, 100g." Includes safety warnings, hazard symbols, and lot number.
    Shipping 2,5-Dichlorobenzene-1,4-diamine should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It is classified as a hazardous material, requiring appropriate labeling and documentation. Transport must comply with local, national, and international chemical safety regulations, ensuring minimal risk of spillage, exposure, or environmental contamination during transit.
    Storage 2,5-Dichlorobenzene-1,4-diamine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Protect from light and moisture. Clearly label the container and keep it away from food, drink, and animal feed. Follow all relevant safety protocols and local regulations for storage.
    Application of 2,5-Dichlorobenzene-1,4-Diamine

    Applications of 2,5-Dichlorobenzene-1,4-Diamine in Industrial Manufacturing

    As a direct manufacturer with decades of experience in specialty amines, we supply 2,5-dichlorobenzene-1,4-diamine in bulk to trusted partners across advanced materials production sectors. This intermediate exhibits selective performance in downstream synthesis, particularly within high-end polymer, pigment, and specialty chemical processes. Below, we detail key commercial application scenarios with focus on integrative industrial standards, precise formulation ratios, processing steps, and resultant end-use articles.

    1. Polymer Intermediate for High-Performance Polyamides

    Engineering plastics producers integrate this aromatic diamine into copolymer and specialty polyamide formulations requiring exceptional thermal and chemical resistance. Our raw material becomes a structural core within the molecular backbone, enhancing mechanical performance and stability under continuous temperature stress in polymer matrix systems used for automotive and electronic components.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems for polymer manufacturing
    • RoHS Directive (2011/65/EU) and REACH Regulation (EC) No 1907/2006 for electronic applications
    • UL Yellow Card for flame resistance certification of polyamide compounds
    • IEC 61249-2-21 for halogen content limitation in electronics substrates

    Typical usage ratio

    • 5–15 wt.% as a diamine comonomer; exact dosage based on desired polymer rigidity, crystallinity, and post-processing requirements.

    Downstream process integration

    • Added to polycondensation reactor following precise pre-drying, concurrent with dicarboxylic acids or anhydrides. The diamine is charged under inert atmosphere at controlled temperature ramps (180–280°C), ensuring complete dissolution and homogeneous reactivity. Used in both batch and continuous polymerization lines.

    Final product types

    • High-temperature polyamide pellets and compounds
    • Glass fiber-reinforced PA composites
    • Thermal management electronic connectors
    • Automotive under-the-hood parts

    2. Synthesis of Specialty Azo Pigments

    Major pigment manufacturers employ our dichlorinated diamine within the production of special azo colorants, owing to its unique substitution pattern that imparts color tone shifts and lightfastness. The molecule functions as a coupling component in diazonium-based syntheses for pigments used in high-value inks, coatings, and plastics demanding strong chemical durability and color retention under UV exposure.

    Industry compliance standards

    • EN 71-3:2019 (Safety of toys—migration of certain elements) for pigment safety in children’s products
    • EU Regulation (EC) No 1272/2008 (CLP) for labeling and safety data
    • ISO 787/2 (Methods of test for pigments and extenders—determination of matter volatile at 105°C)
    • DIN 55990-1 for organic pigment manufacturing

    Typical usage ratio

    • 10–22 mol% as a coupling agent, with adjustments dictated by target pigment chromatic properties and substituent compatibility.

    Downstream process integration

    • Employed at the coupling stage after diazotization of primary aromatic amines, under strictly controlled pH (4–6) and temperature (0–5°C). Incorporated in aqueous or semi-aqueous slurry prior to filtration, washing, and spray-drying. Intermediate purification refines pigment clarity and batch reproducibility.

    Final product types

    • High-stability yellow and red azo pigments
    • Inks for inkjet and screen printing
    • Weather-resistant industrial coatings
    • Masterbatches for plastic coloration

    3. Precursor for Specialty Aromatic Isocyanates (PU Catalysts and Hardeners)

    Advanced polyurethane systems manufacturers employ dichlorinated aromatic diamine as a controlled-feed precursor in the synthesis of specialty aromatic diisocyanates. The resulting diisocyanates and polyisocyanate blends play a critical role in tailored curing agents and catalysts for cast elastomers, structural adhesives, and insulation foams where specificity and reactivity modulation are essential.

    Industry compliance standards

    • ISO 9001:2015 for production QC
    • ISO 14001:2015 (Environmental Management)
    • US EPA TSCA (40 CFR Part 720) for isocyanate handling and new chemicals
    • REACH Annex XVII for restrictions on certain isocyanates

    Typical usage ratio

    • Varies from 3–12 mol% in isocyanate synthesis; titration based on stoichiometric balance with phosgenation agent and target functional group count.

    Downstream process integration

    • The diamine is fed into the phosgenation reactor under tightly controlled anhydrous conditions, preceded by chemical purification to remove trace water and catalysts. Post-reaction distillation ensures purity of diisocyanate product stream for direct formulation into downstream PU systems.

    Final product types

    • Polyurethane hardener blends
    • PU elastomer system components
    • High-performance circuit board encapsulants
    • Structural adhesives and foam insulations

    4. Intermediate for High-Performance Disperse Dyes

    Textile dye producers use our dichlorinated diamine for synthesizing disperse dyes that provide stable coloration on synthetic fibers, especially polyester and acetate. Its molecular architecture enhances hue brightness and sublimation fastness, critical for high-speed printing and fabric finishing where demanding colorfastness is non-negotiable during downstream thermal processing.

    Industry compliance standards

    • Oeko-Tex Standard 100 for harmful substance limits
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals Manufacturing Restricted Substances List)
    • ETAD (Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers) risk assessment protocols
    • GB/T 17644 for general technical specifications of disperse dyes

    Typical usage ratio

    • 8–16 mol% as the coupling component in dye molecule synthesis. Ratio adjusted in multi-step syntheses based on color depth and thermal migration requirements.

    Downstream process integration

    • Engaged in the azo coupling or condensation phase under semi-batch or continuous operations. The diamine is dissolved in select organic or mixed-phase solvents, with pH controls and anti-dust protocols to achieve precise molecular weights and dispersibility. After reaction, dyes undergo filtration, spray-drying, and milling for commercial dye powder supply.

    Final product types

    • Disperse dye powders and pastes
    • Textile inks for polyester fiber
    • High-performance flag and banner printing dyes
    • Thermal transfer inks

    5. Intermediate for Pharmaceuticals: Synthesis of Active Pharmaceutical Ingredient (API) Precursors

    GMP-compliant pharmaceutical manufacturers rely on the diamine as an advanced building block in the synthesis of select APIs and complex molecular scaffolds, especially where dichloro substitution imparts metabolic stability or bioactivity. Tight supply chain control and extensive analytical validation are crucial for this application, including impurity profiling and trace residual control throughout multi-stage synthesis.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.) monographs
    • 21 CFR Part 210/211 (US FDA cGMP regulations)
    • Chinese Pharmacopoeia (ChP) and Drug Master File (DMF) requirements

    Typical usage ratio

    • 0.3–2 molar equivalence as a core intermediate or API side-chain, depending on the target molecule’s synthetic pathway and regulatory submission specification.

    Downstream process integration

    • Charged into the core coupling or acylation step within multi-pot batch reactors. Isolated with high-purity standards via recrystallization, followed by in-process analytical characterization (NMR, HPLC, GC-MS) and cGMP documentation for each synthesis lot, ahead of scale-up to pilot or final API output.

    Final product types

    • Pharmaceutical intermediates for regulated APIs
    • Metabolic pathway modulators
    • Chlorinated aromatic scaffolds for clinical candidates
    • Bulk intermediates for further site synthesis
    Free Quote

    Competitive 2,5-Dichlorobenzene-1,4-Diamine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2,5-Dichlorobenzene-1,4-Diamine: Reliability Built from the Ground Up

    Direct Experience in Manufacturing

    Few molecules offer the kind of versatility we see in 2,5-Dichlorobenzene-1,4-Diamine. Throughout years of hands-on experience, we have treated this compound as more than just another chemical. Our production lines are shaped around its quirks and character. Many customers approach us for a material that blends consistency, purity, and reproducibility, and we have witnessed first-hand how this diamine delivers over long production cycles. Each batch comes off our reactors after undergoing careful controls, guided by a thorough understanding of its reactivity and safety margins.

    Model and Purity

    Manufacturing for those who set high standards requires precise control at every step. We produce 2,5-Dichlorobenzene-1,4-Diamine with a focus on specifications crucial to users who cannot afford unpredictable performance. Our established grade sits within a narrow purity range, tailored for industries such as specialty polymers and dyes where off-spec material can jeopardize an entire process run. Every kilogram tracks back to rigorous process checks, and we audit process parameters continuously to maintain critical parameters like melting point and moisture content. Years spent refining these controls translate into uninterrupted processing for clients, especially where end-use demands repeat accuracy.

    Practical Usage Across Industries

    We have seen this material earn its place in several sectors, not by accident but through real-world results. In the production of high-performance polyimides, our 2,5-Dichlorobenzene-1,4-Diamine has become a trusted component. Chemists appreciate the controlled introduction of chlorine atoms at the 2 and 5 positions, which profoundly influence polymer backbone rigidity and thermal resistance. Dyestuff manufacturers value its predictable reactivity profile, allowing them to achieve deep, stable colorants without chasing after batch-to-batch adjustments.

    Another area where this product proves essential is in the custom synthesis of agrochemicals and intermediates. The defined diamine functionality provides clean reaction sites, reducing occurrence of undesired byproducts that can slow downstream separation or purification. Customers share stories of simplified work-ups, where the purity and consistency of our product have slashed cycle times and improved overall plant uptime.

    What Sets 2,5-Dichlorobenzene-1,4-Diamine Apart

    Chemists who use 2,5-Dichlorobenzene-1,4-Diamine often ask how it stacks up against other chloro-oriented benzene diamines or monomers. Through direct trials, we have measured its performance alongside alternatives like 2,4-dichlorobenzene-1,3-diamine and unchlorinated p-phenylenediamine. Our experience shows that selective chlorine placement imparts distinct benefits. For instance, thermal and hydrolytic stability increase, which supports polymer applications where both heat and chemical attack present real threats. We encourage plant engineers to consider these differences, as a seemingly small substitution could multiply costs related to maintenance or final product reliability.

    Controlling Environmental and Safety Issues

    No discussion about diamines can ignore environmental and worker safety. From the beginning, our approach blends production efficiency with responsible handling. Our facilities run closed-loop systems to keep emissions contained, and waste neutralization procedures form an integral part of our daily process. We have invested in training to ensure our teams understand the implications of handling aromatic diamines, particularly those with chlorine substituents, due to the potential for exposure risks.

    A major area of feedback comes from customers moving to more sustainable operations. They rely on us for not just a raw material, but also for documentation and collaborative support needed for regulatory filings and environmental reporting. We draw from firsthand audits and site visits to keep our MSDS and compliance documents current—based on real production rather than outdated literature references.

    Lessons from Scale-Up and Commercial Production

    Scaling up from laboratory to plant scale brings many surprises, as we experienced early on with this product. Bench experiments often ignore subtle factors like heat release rates or solubility shifts at scale. Over the years, we have tackled challenges such as crystallization bottlenecks and insoluble byproduct formation by adjusting solvents and refining process steps. On one memorable campaign, our team noticed minor color impurities cropping up as production shifted into the third tonnage. Rather than just tightening specifications, we adjusted purification protocols, leading to consistently clear material and fewer downstream filtration issues for clients.

    One aspect we learned quickly: water content in precursor materials made a big difference in the final product's properties. We introduced in-line monitoring and gradually ramped up drying capacity. The improvement was immediate—customer complaints about unpredictable melting point or slow dissolution dropped sharply.

    Supporting Innovation and Downstream Customization

    Our partners in research and development drive us to keep pace with new applications. Laboratories exploring next-generation colorants or specialty plastics often require non-standard specifications. We work directly with technical staff from these companies, modifying process conditions to produce trial lots with adjusted impurity profiles or custom particle sizes. More than once, we have uncovered new processing advantages by collaborating on pilot-scale experiments, such as reducing energy input during synthesis or swapping out hazardous reagents for greener alternatives. Those insights feed back into our standard offerings, benefitting legacy clients and cutting rework rates across the board.

    Differences from Other Diamine Products

    Some buyers wonder whether 2,5-Dichlorobenzene-1,4-Diamine can substitute for similar materials like o-phenylenediamine or 4,4'-diaminodiphenylmethane. Our production teams have tested such substitutions, tracking reaction yields, color development, and filterability in a comparative series. The controlled reactivity of our 2,5-dichloro product often gives tighter, cleaner molecular assemblies in colorant synthesis. The presence of chlorine at the specified positions blocks certain unwanted side-reactions, which would otherwise generate off-shade colors or sticky residues in equipment.

    For polymer customers, moving from an unchlorinated to a dichlorinated diamine can change the balance of mechanical strength and aging properties in final molded parts. Our technical advisors help run side-by-side tests, calling attention to differences noted over months of outdoor exposure or after stress cracking simulations. We document those differences, not just in laboratory terms, but with data that tie back to actual field failures and service complaints. This feedback keeps our product genuinely user-centric.

    Challenges in Raw Material Sourcing

    Global events have pressed raw material sourcing into the spotlight. Our own journey involves navigating shortages, price spikes, and fluctuating availability of upstream chemicals. Early on, we built dual sourcing strategies and long-term partnerships with our key suppliers, sometimes paying a premium to guarantee our plant always has feedstock. Such proactive sourcing takes more upfront work, but has insulated our buyers from missed deliveries or forced reformulation. We share updates about the realities of supply chains with our customers so they can plan inventories and production schedules without sudden surprises.

    Investing in Analytical Controls

    Repeatable quality begins and ends with effective analysis. Every year, new analytical techniques appear, promising deeper looks at micro-impurities or potential contaminants. From the beginning, we invested in HPLC, GC-MS, and colorimetric tests geared toward aromatic diamines. These investments pay off not with just tighter product specs, but in terms of customer trust—users feel confident running our material in sensitive end-use applications, like electronics encapsulation or medical-grade colorants, knowing that trace contaminants have been scrutinized at every production stage.

    Analytical feedback triggers real adjustments on our line, not just for compliance purposes but as part of a cycle of continuous process improvement. A few years ago, analysis flagged unexpected halogenated byproducts, prompting us to shift reagent addition rates. Such incremental changes show up as more predictable product in our customers’ final goods, not just as an improved number on a certificate of analysis.

    Delivering Product Safely and Reliably

    Moving a specialty chemical from our manufacturing floor to customer docks rarely looks the same from one week to the next. We have built our logistics network to handle both drum and bulk shipments, adjusting packaging in response to feedback about warehouse conditions or regional transit norms. Our familiarity with regulations means clients in the EU deal with substances that meet REACH criteria, while those in North America or Asia receive tailored documentation and support for local norms.

    All this comes from long days spent troubleshooting in the warehouse or consulting with freight providers after customs snag a shipment. Those lessons translate to fewer delivery mishaps and less product exposure during transit, with clear labeling and container integrity guaranteed by a crew that knows exactly what’s at stake with each order.

    Regulatory and Sustainability Pressures

    Pressure mounts each year for cleaner, safer, and more accountable production. We take this seriously, not as a matter of trend but from direct requests by customers facing stricter downstream audits. We verify each step in our process aligns with prevailing chemical safety standards, using in-house and third-party audits to demonstrate regulatory fit. More recently, end-users have pushed us on recyclability and low-waste packaging, so we have moved to develop returnable drums and cut the use of single-use liners where practical. These operational investments reduce landfill impact while keeping material quality uncompromised.

    Building Real-World Trust with Customers

    Our most enduring relationships emerge through real partnerships, not just transactional exchanges. Customers that run annual repeat orders often call us with technical questions well beyond a spec sheet. Our technical teams answer these queries with the perspective only a direct manufacturer can bring—sometimes this means tweaking process conditions, or offering alternate storage suggestions for unique climates. Field visits and plant walkdowns shape every update in documentation, with process notes drawn straight from hands-on experience.

    We treat confidentiality and IP protection with the same seriousness as product safety, drawing up NDAs and handling sensitive inquiries discreetly. Our aim is to foster trust through transparent answers and deep subject knowledge, built on years of production, trials, and customer problem-solving.

    Case Studies and Feedback

    Our product history fills with stories that go beyond batch numbers. In one memorable case, an electronics component firm faced issues with yellowing in their molded connectors. After a joint investigation, we identified the link to trace amines present in a competitor’s material. Switching to our 2,5-Dichlorobenzene-1,4-Diamine resolved the color problem and improved part shelf-life, saving them the trouble and cost of warranty returns.

    In another scenario, a textile dyehouse needed a shift toward more stable, deeper colors to keep up with fast fashion cycles. Our technical staff worked on-site for weeks, swapping formulations and monitoring reactor conditions. Their yields rose and complaints about color variability dropped, cementing a partnership that has lasted through several market cycles.

    Approaching the Future Responsibly

    Innovation never stands still, and neither does our process for manufacturing 2,5-Dichlorobenzene-1,4-Diamine. We actively participate in industry forums, share best practices on safer handling, and invest in greener chemistry pilots. Our R&D pilots run new catalyst systems to find energy savings, while regular investment in digital monitoring tightens our resource utilization. Over the past decade, these incremental steps have kept us ahead of regulatory and market changes, with customers benefits translating into higher product quality and fewer operating setbacks.

    Honest Conversations with End Users

    The mark of a manufacturer-built business lies in honest conversations—about capabilities, limits, and improvement plans. We avoid promising zero-defect perfection but do guarantee transparency around test results, processing changes, or raw material shifts. When unexpected issues surface, we tackle them head-on rather than deflecting responsibility, rooting every decision in data and practical experience. Customers value this no-nonsense approach, often sending new project inquiries and involving us early in process development or scale-up trials.

    Conclusion: Earning Each Order Every Day

    We view 2,5-Dichlorobenzene-1,4-Diamine as far more than a commodity line item; every drum and every bulk load represents the outcome of years of investment in people, equipment, and technical rigor. Longstanding collaboration with clients, open feedback, and a strong foundation in manufacturing science keep our standards high and our partners confident. New uses for this product will continue to emerge, and we stand ready to meet each challenge with the same focus that has defined our business from day one.