Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2,5-Dichlorobenzaldehyde

    • Product Name 2,5-Dichlorobenzaldehyde
    • Alias PCB No.9
    • Einecs 210-058-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    990000

    Cas Number 95-98-7
    Molecular Formula C7H4Cl2O
    Molar Mass 175.02 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 61-63 °C
    Boiling Point 265 °C
    Density 1.38 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 111 °C
    Refractive Index 1.601
    Pubchem Cid 7283
    Synonyms 2,5-Dichlorobenzal, 2,5-DCBA
    Smiles Clc1ccc(C=O)cc1Cl

    As an accredited 2,5-Dichlorobenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 100g 2,5-Dichlorobenzaldehyde comes in a sealed, amber glass bottle with a secure screw cap and hazard labels affixed.
    Shipping 2,5-Dichlorobenzaldehyde is shipped in tightly sealed containers to prevent leakage and contamination. The packaging complies with hazardous material regulations, and the substance is transported as a regulated chemical, typically via ground or air freight, with proper labeling and documentation to ensure safe and secure transit.
    Storage 2,5-Dichlorobenzaldehyde should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. Keep the container tightly closed and protected from moisture. Use only chemical-resistant containers. Clearly label all storage vessels, and ensure access is restricted to trained personnel. Avoid storing near heat, flame, or direct sunlight.
    Application of 2,5-Dichlorobenzaldehyde

    Applications of 2,5-Dichlorobenzaldehyde in Industrial Manufacturing

    2,5-Dichlorobenzaldehyde demonstrates essential value as a building block intermediate across several industrial sectors, where its defined reactivity and consistent purity support compliant and high-yield production processes. Below, we detail its key real-world manufacturing applications, focusing on the specific regulatory context, typical incorporation rates, downstream integration, and final product outcomes within each market segment.

    1. Agrochemical Synthesis (Herbicide Intermediate)

    Global agrochemical manufacturers use 2,5-Dichlorobenzaldehyde as an intermediate to synthesize selective herbicides such as dicamba and related dichlorinated aromatic herbicides. It enters multi-step coupling and acylation reactions, ensuring high conversion yields under closely monitored operational controls. The sector prioritizes compliance with international pesticide ingredient regulations, traceability, and audits for batch consistency from raw material sourcing through to final formulation blending.

    Industry compliance standards

    • FAO/WHO Specification for Pesticide Active Ingredients
    • EU Regulation (EC) No 1107/2009 (Plant Protection Products)
    • ISO 9001:2015 (Quality Management Systems in Agrochemical Production)
    • China GB/T 16030-2020 (National Agrochemical Standards)

    Typical usage ratio

    • Applied at 0.6%–1.2% molar equivalence relative to final active ingredient basis in multi-kilogram synthesis. The precise ratio adjusts based on target herbicide structure and required process yield optimization.

    Downstream process integration

    • Integrated as the nucleophilic aromatic precursor in aromatic acylation and chlorination stages; added to reaction vessels after initial solvent system preparation and base treatment, facilitating coupling with downstream acid chlorides or amines.

    Final product types

    • Technical-grade herbicide actives (e.g., dicamba, dichlorinated benzoic acids)
    • Formulated water-dispersible powder and liquid herbicide concentrates
    • Bulk intermediates for further downstream protection formulations

    2. Pharmaceutical Intermediate (API Synthesis Route)

    Pharmaceutical batch plants employ 2,5-Dichlorobenzaldehyde in several multi-step synthesis pathways, especially for manufacturing benzimidazole derivatives and antifungal or antibacterial APIs. Its defined aromatic substitution profile lends advantages in regioselective condensation or oxidation steps, aiding in strict impurity profile management required for regulated pharmaceutical synthesis. All stages undergo strict cGMP documentation, with consistent traceability from incoming lots to released APIs to meet regional pharmacopeia standards and international ICH guidelines.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP–NF (United States Pharmacopeia)
    • EU GMP Part II: Basic Requirements for Active Substances
    • JP (Japanese Pharmacopoeia), where applicable

    Typical usage ratio

    • Typically 0.5–1.7 mole equivalents per condensation or cyclization reaction, as defined by synthetic route and intended API target. Ratio optimized to minimize byproduct formation during each batch.

    Downstream process integration

    • Charged into glass-lined reactor vessels at the initial condensation step, often under inert atmosphere with acid catalysts, prior to reduction or heterocyclization into final pharmacophores.

    Final product types

    • Antifungal agents (e.g., benzimidazole class APIs)
    • Pharmaceutical intermediates for further derivatization
    • Active pharmaceutical ingredients registered in regulated markets

    3. Dye and Pigment Synthesis

    Major pigment manufacturers incorporate 2,5-Dichlorobenzaldehyde into advanced azo dye and pigment production lines, leveraging its dichloro-functionalized benzaldehyde ring to guide color fastness and heat resistance properties. Its consistent purity and reactivity facilitate controlled azo-coupling or condensation reactions, supporting compliance with regulatory frameworks around aromatic amine content and eco-toxicological standards for industrial coloring agents used in plastics, coatings, and textiles.

    Industry compliance standards

    • REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) EU No. 1907/2006
    • EN 71-3 (Safety of Toys - Migration of Certain Elements, relevant to pigment migration)
    • OEKO-TEX® Standard 100 (Textile chemicals and colorants safety)
    • BfR IX (German Recommendations on Food Contact Colorants, where pigments are indirectly used)

    Typical usage ratio

    • Used at 0.8%–3.5% by weight in initial coupling batch, tailored depending on target pigment structure, color tone, and fastness requirements.

    Downstream process integration

    • Reacted in batch or continuous-flow synthesis as the aldehyde component in azo-coupling or direct condensation, often after sulfonation/halogenation of coupling partners; product isolation by filtration and drying.

    Final product types

    • Synthetic azo and anthraquinone dyes
    • High-stability pigments for plastics and industrial coatings
    • Colorants for inks and textile printing pastes

    4. Chemical Aromatic Intermediate for Fine Chemicals

    Specialty chemical manufacturers rely on 2,5-Dichlorobenzaldehyde as a pivotal intermediate in producing a diverse portfolio of fine chemicals, particularly for the synthesis of specialty aromatics, photoinitiators, and certain polymer modifiers. Its dual chlorination enables targeted downstream substitutions and oxidative modifications for tailored aromatic end-structures. This segment manages compliance with chemical control regimes, extensive end-use declarations, and site-specific quality systems aligned with customer downstream processes.

    Industry compliance standards

    • REACH Registration (for non-pharmaceutical, non-agrochemical EU uses)
    • ISO 14001:2015 Environmental Management Systems
    • OECD Good Laboratory Practice (GLP) for chemical intermediates, when used in regulated analytical workflows
    • Customer-declared end-use registration or notification, as mandated by jurisdiction (e.g., U.S. TSCA reporting)

    Typical usage ratio

    • Ranges from 1.0%–4.0% by weight of initial batch, depending on final transformation yield and required aromatic substitution pattern. Inclusion rate calculated following preliminary bench-studies or pilot-scale adjustment.

    Downstream process integration

    • Introduced in process step following solvent swap and temperature adjustment, most often by direct charge to methylation, nitration, or oxidative cleavage step, dependent on target molecule.

    Final product types

    • Photoinitiators for UV-curable coatings
    • Aromatic ring-modified specialty monomers
    • Advanced intermediates for further specialty chemical synthesis

    5. Fragrance Ingredient Intermediate

    Selective aroma and fragrance compound producers utilize 2,5-Dichlorobenzaldehyde to build functionalized aromatic alcohols and aldehydes for use in household and industrial scent formulations. The reactivity profile allows for precise substitution and reduction steps that generate aldehydic notes required in fragrance blending, while production remains under compliance with global hazard labelling and purity disclosure regimes due to downstream consumer exposure risk.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association)
    • EU CLP Regulation (EC No 1272/2008) for classification, labelling, and packaging
    • ISO 9235:2013 (Aromatic raw materials – vocabulary and classification)
    • GHS/OSHA HCS requirements for safety data disclosure

    Typical usage ratio

    • Normally 0.2–0.6 w/w% relative to total reaction mass in fragrance intermediate synthesis; level is strictly managed to control both aroma intensity and compliance with finished blend threshold limits.

    Downstream process integration

    • Processed via catalytic reduction or condensation after solvent pre-mixing and pH adjustment; typically forms intermediate alcohol or changes aldehyde side-chain position for further use in proprietary blends.

    Final product types

    • Functionalized aromatic alcohols and aldehydes for fragrance blending
    • Semi-finished aroma chemicals supplied to compounding houses
    • Final scent blends for detergents, air care, and industrial cleaning products
    Free Quote

    Competitive 2,5-Dichlorobenzaldehyde prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2,5-Dichlorobenzaldehyde: A Manufacturer’s Perspective on Quality, Application, and Advantage

    Understanding 2,5-Dichlorobenzaldehyde: A Reliable Building Block

    Making chemicals isn’t just about combining ingredients. We spend years refining our approach to each molecule because end-use and downstream performance depend on subtle choices we make at every step. In our experience, 2,5-Dichlorobenzaldehyde stands out as a core intermediate, especially valued by specialty coatings formulators, agrochemical producers, and developers of advanced dyes. It enters the market as a white to pale yellow crystalline solid, defined by a sharp, penetrating aromatic odor. The consistency clients expect requires attention: melting range control, level of residual moisture, and purity above 99 percent. These are not just numbers; they reflect how the material will behave in reactions, impact batch yields, and affect downstream isolation.

    How Our 2,5-Dichlorobenzaldehyde Performs in the Field

    We receive feedback from ink makers and pigment formulators about the difference in productivity when using this aldehyde. In batch color chemistry, reproducibility makes the real difference between profit and waste. Our product maintains an identity prescribed by CAS RN 117-42-0. It shows consistent spectral data and twin chlorine substitution at precise ring positions, leading to predictable reactivity—a trait that many downstream processes count on.

    During agricultural synthesis, it serves as an intermediate for herbicides and fungicides where impurities can either degrade actives or hinder catalyst performance. Years ago we found that by tightening our washing and drying steps, unwanted trace organics—hard to catch using basic TLC—go down, translating to longer shelf-life and cleaner conversion rates for our clients. Sometimes the difference shows up in the form of more stable pre-mixes, or more uniform crystal habits in final actives.

    Purity, Impurity Profiles, and Making a Difference

    Purity is not a one-size-fits-all number. We’ve worked with companies that require routine 99.5 percent GC purity, but in certain dye applications, even minor levels of ortho or meta isomers or trace iron from catalyst carryover can ruin downstream color intensity. One of the lessons we learned came from a customer focused on high-value anthraquinone dyes. Their trace residue standards meant switching to glass-lined reactors to avoid contamination. We also invested in finer control of the oxidation step, using high-grade reagents and real-time temperature monitoring. This extra measure means batches run cleaner, improving long-term relationships with clients who can't afford to risk off-color or inconsistency. Other manufacturers may use bulk processing routes designed only for commodity-level grade, but we work from the point of view that every customer's process will expose shortcomings in our own.

    Comparing with Other Chlorinated Benzaldehydes

    There’s no shortage of chlorinated benzaldehydes, but position and substitution matter. Some customers come to us asking for comparisons between 2,5-dichlorobenzaldehyde and 3,4-dichlorobenzaldehyde. At the level of chemical synthesis, the placement of chlorines influences electron density and dictates how well the benzaldehyde groups react in condensation steps or nucleophilic substitutions. In dye synthesis, using the wrong isomer can drop conversion efficiency by double digits and throw off hue balance in the final color.

    With experience comes an understanding that even small differences in raw material source can create variability—not simply because of base structure, but due to stubborn by-products like 2,3- or 2,4-substituted isomers. We source chlorobenzene and manage chlorination conditions to favor 2,5-substitution, keeping an eye on temperature and pressure to discourage side-product formation. The result isn’t just high assay, but fewer surprises for process chemists downstream.

    Why Manufacturers, Not Traders, Hold the Key to Consistency

    Over the years, we’ve observed shifts as more manufacturers raced to meet demand by increasing line speed or outsourcing key steps. From the outside, packaging might look identical regardless of where it’s filled. In practice, subtle changes—such as shifting the chlorination catalyst, adjusting solvents, or using cheaper water for washing—leave behind tiny but crucial impurities.

    We have spent resources not just on new reactors, but on closed-loop quality feedback with long-term users. Specifications can list a melting point of 58.5–60.5°C and loss on drying below 0.2%, but in our daily operations, the test that matters most is how well our 2,5-dichlorobenzaldehyde performs in the actual formulations users care about. We’re contacted not only for routine orders, but for process troubleshooting. Sometimes the problem isn’t visible on a simple COA but only emerges in real-world blending, or after a batch comes off a commercial line slightly brownish instead of white. In these cases, manufacturers have the inside track, as we’ve already seen and adjusted our process variables on scale-up runs, minimizing learning curves for customers.

    Applications: What Sets 2,5-Dichlorobenzaldehyde Apart in Real Use

    In the field of pharmaceuticals and fine chemicals, this product often forms the lynchpin for construction of more complex molecules where ring substitution must remain exact. Take, for example, its use in the synthesis of intermediates for anti-infective agents or in further chlorination or oxidation where position control governs end yield. When chemists call with concerns about pink or brown tints in their products, it often leads back to aldehyde feedstock—whether off-commercial samples from generic sources or containers that have absorbed trace moisture during transit.

    With every batch, we subject samples to both GC-MS and wet chemistry to watch for trace chlorinated benzoic acids or solvent artifacts left from previous runs. Color metrics—measured in APHA units—give us a window into batch cleanliness. These aren’t just bureaucratic numbers, but practical metrics that help formulators avoid headaches with downstream purification or unexpected reaction byproducts.

    Customers report fewer side reactions with our stock because we focus on tight oxidation control and fresh packing. The difference isn’t always visible to the naked eye, but shows up in final product yields and fewer QC hold-ups.

    Real-Life Challenges and Adaptations

    Sometimes making a better chemical means tackling challenges beyond the flask. We’ve encountered cases where regional regulations on wastewater meant redesigning parts of our chlorination sector, switching over to closed-loop water purification. While upfront costs rose, the resulting product purity improved, with lower organic carry-over—factoring into less need for extra purification by customers. These details, which might sound routine, in practice reduce time and cost for users: less time running additional washes means faster throughput in their plant.

    We also hear from customers about packaging. 2,5-Dichlorobenzaldehyde can pick up moisture and degrade if containers don’t protect against humidity. We adapted with foil-lined drums, vacuum-sealing, and adding humidity indicators to each shipper. Feedback shows this approach leads to fewer complaints about lumping or partial hydrolysis, especially for overseas shipments facing unpredictable weather.

    Supporting Evidence for Product Reliability

    Years of operational experience show that manufacturers who invest in process monitoring see fewer out-of-spec complaints and less client-side troubleshooting. Over 95 percent of repeat orders from key markets validate our outcomes: less batch-to-batch variability, more predictable conversion rates in large-scale synthesis, and reduced need for off-cycle material returns.

    A testament to reliability comes from a long-standing partner in the pigment industry. They once relied on mixed-source material and suffered end-user complaints about color shifts. By switching to our tightly controlled output line, they saw complaints drop to near zero, and waste decreased by more than 8 percent by weight over a six-month comparison. These types of performance gains translate into actual cost savings—more than any standard spec sheet can communicate.

    Continuous Development for Application Needs

    Chemical manufacturing demands flexibility. Standard products don’t always fit evolving needs, especially as environmental and performance requirements change. A few years ago, as regulations tightened on allowable aldehyde residues and potential nitrosamine precursors, we upgraded our purification systems, using additional liquid–liquid extractions and custom chromatography. This brought detectable impurities down to below 0.05 percent by weight, winning us more contracts with highly regulated European users.

    In some sectors—especially for companies synthesizing pharmaceutical actives or crop protection compounds—this detail means the difference between material acceptance and rejection. By working closely with process development teams at the client end, we can sync our production parameters to what matters for their reactors, whether it’s tighter amine compatibility, better solubility, or smoother filtration across process steps. Having an in-house analytical department helps cut response times, since we can pull and run comparison samples without waiting days for outside feedback.

    Handling Safety and Regulatory Compliance Face to Face

    Working as manufacturer, attention to safety and compliance extends from plant floor to packaging dock. Years of handling chlorinated aromatic aldehydes taught us to mind not just the finished product but atmospheric and waste management. Monitoring air emissions limits exposure risk for staff—something that shows up again in finished batch purity. Regular operator training reduces both accidents and cross-contamination.

    Our teams undergo site and personal monitoring to keep exposure well below occupational limits. Product destined for North America or the EU faces extra scrutiny—each load supports batch-level data for regulation-inspired audits. This operational transparency means when an end-user’s QA team asks for documentation, we produce it with traceable linkages to source data. Such responsiveness leads to long-term supply agreements for value-driven partners.

    Economic Influences on Manufacturing and Customer Choice

    In recent years, raw material fluctuations hit every part of the chemical value chain. Markets have seen sharp swings, with import bottlenecks and price upticks in feedstock chlorobenzene or reagents. The pressure to cut corners grows, tempting less-established outputters to shift process times or blend off-grade lots to keep up with demand. From years of experience, the fallout from these choices lands on users—sometimes in the form of high impurity batches, missed syntheses, or scrapped lots.

    We welcome direct communication from customers, sometimes opening our process documentation for client-side inspection. This ability to trace back each finished batch not only reassures our partners but inspires confidence for future formulation work.

    Listening to Customer Experience and Real-World Feedback

    A manufacturer’s reputation rises or falls on how products perform in the field. We learn more from customer feedback than any internal meeting. Once, a batch arrived at a long-time user’s site with an unexpected increase in headspace pressure. After investigation, we traced the culprit to minor solvent residue carryover from a faster drying step. While specs did not flag the issue, our open reporting structure allowed the user to reach a quick process fix. Lessons like this drive constant small-scale improvements.

    On another occasion, an agricultural company in Southeast Asia reported unusual sediment in liquid dispersions. A site visit revealed these traces came from cross-contamination with unrelated aromatic aldehydes used in the same multi-purpose plant. The solution meant investing in new cleaning protocols and batch segregation. We find practical stories like these show why large-scale, in-house manufacturing control goes a long way beyond any off-the-shelf spec.

    Advantages of Manufacturer-Direct Sourcing

    In our view, direct access to the manufacturing line provides buyers a clear advantage, especially for high-sensitivity end-use. Precise control over starting conditions, temperature ramps, and residence times means fewer surprises—and more cost certainty for users who work at ton-scale.

    For partners aiming to develop novel syntheses or extend process windows, open dialogue between the process engineers and our own plant team can shorten development cycles. Batch customization—within defined performance limits—becomes possible. For example, we’ve supplied fractions with higher or lower solubility points depending on downstream crystallization needs.

    Having a steady source means users avoid juggling multiple vendors and batch variances. Through years of doing business, our operational flexibility provides continuity in both classic and new process chemistries. End users can rely on a forward-looking supply model, adapting specifications in pace with market innovation.

    Global Supply and Logistical Considerations

    Shipping conditions shape product performance, especially for aromatic aldehydes. Over time, we adapted to regional weather and customs delays with new solutions: double-walled containers for tropical climates, desiccant packs for longer sea routes, and tailored drum types for frequent inbound checks. Our direct relationship with shippers enables us to fix issues in real time, cutting down on customs holdups and transit stress for sensitive shipments.

    Timely documentation and accurate advance sample turnover eliminate unnecessary batch rejections. Recurring reviews with shippers, regulatory agencies, and port controllers build a reliable end-to-end supply chain—one less likely to let buyers down at critical moments.

    Building Trust with Each Lot Produced

    Filling orders is not the same as supplying a solution. Each shipment stands behind years of refining process, teamwork, and learning from successes and failures. Whether destined for research, industrial scale-up, or repeat production, the care invested shows in reduced complaint rates, faster formulation times, and better downstream recoveries. Real manufacturing means standing behind every batch, not blending away deficits or shifting problem lots out the door.

    Summary: The Real Value Behind 2,5-Dichlorobenzaldehyde

    In the hands of an experienced manufacturer, each drum or bag of 2,5-dichlorobenzaldehyde brings not just a product, but also the benefits of scientific investment, field-tested handling, and real-world collaboration with global users. Careful attention to every step—raw input selection, operation monitoring, packing, and customer feedback—changes everything for the better. This isn’t just a commodity, but a building block that helps partners meet their own technical, operational, and regulatory benchmarks. In our experience, quality is not a static standard, but an ongoing conversation with every formulator, chemist, and supply chain manager along the way.