Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2,5-Dichloro-P-Xylene

    • Product Name 2,5-Dichloro-P-Xylene
    • Alias p-Xylene, 2,5-dichloro-
    • Einecs 210-070-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    436904

    Chemical Name 2,5-Dichloro-p-xylene
    Cas Number 624-24-8
    Molecular Formula C8H8Cl2
    Molecular Weight 175.06 g/mol
    Appearance White to pale yellow solid
    Melting Point 51-53 °C
    Boiling Point 240-242 °C
    Density 1.21 g/cm³
    Solubility In Water Insoluble
    Refractive Index 1.554
    Flash Point 112 °C (closed cup)
    Purity Typically ≥98%

    As an accredited 2,5-Dichloro-P-Xylene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2,5-Dichloro-P-Xylene is packaged in a 100g amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 2,5-Dichloro-p-xylene should be shipped in tightly sealed, chemical-resistant containers, protected from moisture and direct sunlight. It must comply with relevant transport regulations (such as DOT, IATA, or IMDG), often classified as hazardous. Appropriate hazard labels and documentation are required to ensure safe handling and to prevent leaks or accidental exposure during transit.
    Storage 2,5-Dichloro-p-xylene should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers. Keep away from heat, flame, and direct sunlight. Ensure storage area is clearly labeled and chemical is protected from physical damage. Use secondary containment to prevent spills or leaks.
    Application of 2,5-Dichloro-P-Xylene

    Applications of 2,5-Dichloro-P-Xylene in Industrial Manufacturing

    2,5-Dichloro-P-Xylene is a critical intermediate utilized by specialty chemical manufacturers in the synthesis of higher-value downstream products, primarily within the fields of advanced polymers, agrochemical intermediates, high-performance coatings, and liquid crystal materials. As an experienced manufacturer, we supply this raw material for tightly regulated formulation processes, where precise composition and process control directly influence application performance and end-use compliance. Below, we outline its major industrial application scenarios, including regulatory alignment, process integration, and end-use details.

    1. Monomer Precursor for Polyarylate and Polycarbonate Production

    In aromatic polymer production, 2,5-Dichloro-P-Xylene acts as a key monomer feedstock. Leading manufacturers of heat-resistant engineering plastics use this chlorinated xylene derivative in the condensation polymerization stage, where it introduces controlled halogen functionalities to the polyarylate and polycarbonate backbones, which enhances flame retardancy and dimensional stability. Accurate dosing of this raw material is essential for optimal polymer chain propagation and to meet strict downstream end-use quality benchmarks for electrical, automotive, and aerospace component suppliers.

    Industry compliance standards

    • UL 94 (Flammability of Plastic Materials for Parts in Devices and Appliances)
    • IEC 61249 (Materials for printed circuit boards and other interconnecting structures)
    • ISO 9001:2015 (Quality management systems applied to polymer manufacturing)
    • RoHS & REACH (for electronic and automotive polymer grades)

    Typical usage ratio

    • Utilized at 15–30% molar ratio relative to total diol or diacid monomer content, adjusted per target chlorine incorporation and polymer viscosity grade requirements.

    Downstream process integration

    • Charged into the esterification or transesterification reactor during monomer synthesis; reacts under controlled temperature and catalysis to achieve halogenated polymer chain segments prior to pelletizing and extrusion.

    Final product types

    • High-temperature polyarylate sheets
    • Halogenated polycarbonate molding compounds
    • Electronic device housings and connectors
    • Automotive under-hood plastic components

    2. Intermediate for Agrochemical Active Ingredient Synthesis

    Manufacturers in the agrochemical sector employ 2,5-Dichloro-P-Xylene as a strategic intermediate during the synthesis of specific herbicide and fungicide active ingredients. Its chlorine-substituted aromatic structure supports direct functionalization reactions, enabling creation of active moieties for downstream agrochemicals. Well-defined stoichiometry and controlled introduction into multi-step organic synthesis are critical for yield optimization, traceability, and meeting agricultural regulatory constraints.

    Industry compliance standards

    • FAO/WHO Technical Specifications for Pesticides
    • ISO 17025 (Testing and calibration laboratories – agrochemical sector)
    • Good Manufacturing Practice (GMP) for Active Substances (European Commission Regulation EC 1107/2009)
    • GLP (Good Laboratory Practice for residue analysis)

    Typical usage ratio

    • Dosed at 5–18% by mass in initial reaction batches, varying with route and required concentration of dichlorinated aromatic core in the target molecule; adjusted per desired substitution degree.

    Downstream process integration

    • Fed into chlorination or acylation reactors as a starting aromatic substrate; progresses through further halogenation, nitration, and/or amination steps before coupling into the final agronomically active structure.

    Final product types

    • Chlorinated phenoxy herbicide precursors
    • Triazole fungicide intermediates
    • Precursor compounds for select insect growth regulators

    3. High-Purity Precursor for Liquid Crystal Monomer Synthesis

    Specialty chemical producers utilize 2,5-Dichloro-P-Xylene in the synthesis of high-purity monomers destined for liquid crystal display (LCD) material applications. Its role is especially critical in providing para-oriented dichlorinated aromatic rings that enable precise molecular structure, dielectric properties, and thermal stability in downstream LC compounds. Laboratories and production lines emphasize ultra-high-purity grades and tight manufacturing control to ensure that residual contaminants remain within strict electronics industry thresholds.

    Industry compliance standards

    • JEITA ET-7302: LCD materials quality standards
    • IEC 62047-1: Micro-electromechanical systems (MEMS) – Part 1: LCD bulk materials
    • ISO/TS 16949 (Quality management for automotive electronics)
    • ISO 14644 (Cleanroom and associated environments during liquid crystal material production)

    Typical usage ratio

    • Typically used at 10–22% by mol in condensation or cross-coupling stage, depending on target molecular geometry, birefringence requirements, and downstream integration pathway.

    Downstream process integration

    • Undergoes selective bromination or coupling reactions in organic synthesis modules; product is purified via distillation and column chromatography prior to condensation into liquid crystal monomers.

    Final product types

    • Terphenyl and biphenyl LCD monomers
    • Liquid crystal prepolymers for display substrates
    • High-precision LC mixtures for electronic component production

    4. Precursor for Advanced Industrial Coatings and Resins

    In the industrial coatings arena, resin manufacturers integrate 2,5-Dichloro-P-Xylene as a principal monomer into condensation and copolymerization reactions, engineering high-performance, chemically resistant coating resins for anti-corrosive and high-temperature applications. Its dichloro-functional groups impart improved chemical inertness and impact resistance, extending the service life of finished protective coatings applied in harsh or high-load environments—such as marine, petrochemical, and transportation infrastructure.

    Industry compliance standards

    • ASTM D7187 (Durability of Coatings in Severe Environments)
    • ISO 12944 (Corrosion protection of steel structures by protective paint systems)
    • REACH Annex XVII (Restrictions on specific hazardous substances in coatings)
    • ISO 14001 (Environmental management for coatings manufacture)

    Typical usage ratio

    • Added at 8–20% by weight of total monomer blend, tailored to achieve target chlorine content and mechanical properties for specified application segment.

    Downstream process integration

    • Enters the polycondensation reactor as a dichlorinated aromatic component, where it couples with glycols or acid chlorides under acid catalysis to build tailored resin backbones before solution blending and curing.

    Final product types

    • Heavy-duty anti-corrosive paint binders
    • Heat-resistant industrial varnishes
    • Chlorinated resin-based concrete coatings
    • Pipeline and tank linings in the petrochemical sector
    Free Quote

    Competitive 2,5-Dichloro-P-Xylene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2,5-Dichloro-P-Xylene: A Key Ingredient Backed By Practical Experience

    Introduction to 2,5-Dichloro-P-Xylene

    In our years producing specialty aromatic compounds, we have seen growing demand for reliable, reproducible 2,5-Dichloro-P-Xylene. In practice, chemists and industrial processors rely on this molecule for its consistent performance in synthesizing high-value target molecules. Our process for 2,5-Dichloro-P-Xylene leverages many cycles of optimization, feedback from long-term partners, and practical focus to ensure each batch meets the precise requirements of various downstream uses.

    Our Product Model: Real-World Process, Not Just a Label

    What sets our 2,5-Dichloro-P-Xylene apart starts at the feedstock and flows through every step of production. We select raw materials based on supply chain transparency and minimal impurity profiles. At every stage—from chlorination through crystallization and packaging—routine checks keep purity within narrow bands. We tailor lot sizes to support both small-scale labs and full production plants. Our product typically appears as a white crystalline solid, with minimal yellowing and low dust content. Moisture is kept below trace detection limits, based on practical storage and transit observations from real users.

    Our main grade meets a minimum of 99.5% GC purity, with chlorine and residual aromatic isomers controlled to low ppm levels. While bulk users often request lots between 100 kg and several metric tons, we have found that smaller R&D groups benefit from sub-kilogram lab packs in tamper-resistant packaging. Each container receives a tamper evidence seal, based on stories we collected from early adopters who shared concern about in-transit handling. By listening to hands-on users, we avoid abstract “quality” promises and focus on what actually shows up at your loading dock.

    Why Care About 2,5-Dichloro-P-Xylene?

    From our own experience working directly with formulators and process chemists, the compound serves as a linchpin for productions where every percent purity and impurity makes a difference. For resins, dyes, and pharmaceuticals, too many off-spec batches come down to raw material inconsistency. Our partners in pigment manufacturing have pointed out that off-shade color frequently traces back to aromatic feedstock purity, not to the fancy equipment at their plant. Likewise, one pharmaceutical client showed us lot-to-lot assay drift traced right back to unknown aromatic impurities. In real terms, suppliers who produce 2,5-Dichloro-P-Xylene without consistent internal controls push the headache downstream.

    Within our production, regular NMR and GC-MS spot checks help keep not only the major purity on target, but also limit those trace contaminants that seldom show up on broad supplier data sheets. Attention to minor isomers like 2,3-dichloro and 2,6-dichloro variants matters because some applications in pharmaceuticals cannot tolerate more than trace contamination of these analogues. We record not only our own QC numbers, but also invite rigorous audits from customers. This ongoing scrutiny makes our process resilient to raw material fluctuations and seasonal supply challenges, something we have observed too often with far-flung, lightly audited producers.

    Specifications Crafted From Actual Use Cases

    To set our specifications, we’ve worked backwards from pain points voiced by customers using less predictable sources. One client in advanced materials testing flagged problematic shifts in melting point, which their end users attributed to minor aromatic contaminants. In another case, a colorant manufacturer saw filtering challenges and resin-fill defects with off-ratio dichlorinated isomers. These stories pressed us to focus on more than high-level purity numbers. Granular control over isomer distribution, moisture, residual chlorobenzenes, and volatiles now form key parts of our release criteria.

    Moisture content proved to be a recurring theme. We found that even small traces disrupt downstream reactions or skew test results, especially for R&D teams who lack drying infrastructure. By working directly with them, we saw value in setting practical, instrument-backed limits on water, not just trusting to “dry” process steps. Additionally, we handle all lots in temperature- and humidity-controlled environments, and package with desiccant inserts to keep these levels consistent well beyond our doors.

    Where 2,5-Dichloro-P-Xylene Gains Influence: Applications, Not Just Assumptions

    We’ve supplied large volumes of 2,5-Dichloro-P-Xylene to companies involved in specialty polymer synthesis, where it serves as a starting point for rigid polyesters and heat-resistant resins. According to feedback from these clients, purity fluctuates from vendor to vendor, but the downstream result—resin brittleness or flexibility—depends heavily on consistent aromatic character. In dye manufacturing, the dichloro pattern in the para position enables vivid, stable colors with high chemical resistance, something achieved only with reliable input material quality. Our product has supported both high-throughput bulk lines and small-scale, specialty pigment runs, each reporting on how important lot-to-lot consistency remains.

    Pharmaceutical intermediates represent another area where our experience counts. Several of our clients synthesize building blocks for APIs using this compound, and have worked closely with us to identify process vulnerabilities. Failures in purity or contamination by close isomers can narrow the therapeutic window or complicate downstream separation steps. After inspecting production line reject logs, one partner shared that minor byproducts in our competitors’ material extended their purification runtime and increased solvent costs. By applying lessons from these reports, we set stricter carryover controls, helping reduce downstream headaches and wasted material.

    We learned the importance of robust analytical support by helping troubleshoot batch anomalies on customer lines. Instrument calibration shortcuts show up eventually in drift, but careful duplication of analytical methods—GC, NMR, and IR—across both our site and the clients’ labs helps close gaps before they become supply failures. Investment in new direct-injection GC methods stemmed from these collaborations, not just an abstract “commitment to quality.” This analytical transparency helps both sides—manufacturer and user—stay aligned on every shipment.

    What Sets 2,5-Dichloro-P-Xylene Apart From Similar Compounds

    The aromatic chemical world includes several close relatives of 2,5-Dichloro-P-Xylene, yet practical differences alter application outcomes. 2,3- and 2,6-dichloro-p-xylene isomers yield different regioselectivity in synthetic reactions, often complicating downstream transformations. We have watched customers trial low-purity, isomer-mixed feedstocks and run head-on into unpredictable yields and more complicated purifications. Even the best-case scenario—cost savings from a cheaper, unsorted mixture—ends up getting erased by lower batch yields and increased analytical burden.

    Compared to monochlorinated xylene derivatives, 2,5-Dichloro-P-Xylene offers greater chemical rigidity and selective reactivity. Its symmetry plays a role in dye molecule alignment and crosslink potential in specialty polymers. We keep close tabs on how downstream transformations—oxidations, coupling reactions, and halogen exchanges—proceed cleanly only with a uniform and well-identified aromatic input. Isomeric impurities, even at low levels, create noisy backgrounds during downstream HPLC and GC analysis, leading to data headaches for QA teams.

    In pharmaceutical workups, the presence of para-dichloro substitution often allows more straightforward ring functionalization and reduces challenges in post-reaction cleanup. Real-world batch logs from API contract manufacturers highlight how even minor aromatic impurities can introduce out-of-specification outliers. Our focus on maintaining low levels of these contaminants arises not from generic “customer feedback” but from hands-on site visits and tracking actual process bottlenecks over years of collaboration.

    Customers’ Pain Points Drive Our Process Innovations

    Through site visits and regular production reviews, we have come to understand the practical difficulties our customers face with material lots from less rigorous sources. We inspected their warehouse practices and observed, for example, how bulk handling under warm and humid conditions led to caking and compaction—issues amplified by moisture-sensitive operations downstream. In response, we invested in new drum linings and revised pallet protocols to maintain product flow characteristics and support robotic handling.

    Another key area emerged from user feedback regarding trace volatiles. Some clients in the electronic materials sector documented failures during device encapsulation that they traced back to trace-level aromatic byproducts. We responded by intensifying post-synthesis purging steps and expanded gas-chromatographic screening to ensure not only target purity but also minimal volatile carryover, increasing the material’s reliability in highly sensitive environments.

    We learned that even minor packaging inconsistencies—physical strength, chemical compatibility, or improper sealing—could compromise downstream trace analysis or end-use performance. By working directly on customers’ workflows, we now use robust packaging that resists permeation, tampering, and accidental contamination. Years of troubleshooting logistics in hot climates led us to anti-static, double-layer film and crush-resistant outer drums. These changes stemmed from solving real problems together, not from copying general industry trends.

    Supporting Safe and Reliable Handling—Built on Practice

    We got firsthand exposure to the handling demands in both large industrial and small technical environments. 2,5-Dichloro-P-Xylene does not present the same handling risks as many alkyl aromatics with higher volatility, but safe practice remains non-negotiable. We provide clear, practical advice—based on decades in our own production bays—for storage, PPE, and spill response, instead of passing generic safety data sheet jargon. Each customer program receives residue test results, firsthand storage recommendations for different climates, and clear warnings where static, moisture, or contamination could trigger issues.

    We watched competitors gloss over the importance of physical state consistency, only to create downstream dosing problems. With us, lots always ship as free-flowing crystalline solids, easy to measure and dissolve, even in the high humidity of tropical shipment routes. We maintain frequent feedback loops with key users to refine this handling experience. We have come to value these late-night troubleshooting calls and remote troubleshooting sessions, which often lead to real enhancements in how we monitor and package each batch.

    Trust Built on Transparency and Repeat Experience

    Our position as a direct manufacturer—rather than a trading platform—offers customers a window into the material’s journey from base chemical to finished pail. We welcome audits, sample pulls, and method crosschecks on-site. Clients have watched their orders being filled and measured, not just reading printed test results. We publish batch-level analytics, trace impurity profile, and historical trending data. By inviting customers to inspect our production facilities, we replace guesswork or abstract trust with real, firsthand evidence.

    We learned this transparency builds more robust supply relationships that survive market volatility and shipping disruptions. During times of global supply strain, many buyers turned to new, unverified vendors and faced a surge in inconsistent quality and sudden lot failures. Our regular users reported that transparency and hands-on partnership—knowing who actually produced the material—provided reliability when supply got tight, because we maintain strategic inventory, know our batch traceability inside out, and react to market spikes with clear communication rather than hollow promises.

    Industry Trends & Future Outlook

    Over recent years, tightening regulatory oversight on aromatic chemicals has put additional scrutiny on trace contaminants, packaging practice, and environmental controls. We have responded by implementing closed-loop solvent recovery and emissions abatement, not just to meet paperwork requirements but to cut real operational risks. Ongoing dialogue with local inspection authorities means we adapt quickly to regulatory proposals, providing users with up-to-date compliance documentation, not after-the-fact paperwork.

    We also prepare for coming trends like digital batch tracking, real-time shipment analytics, and circular economy integration. Users increasingly expect granular data and auditable records for their own compliance reports. By investing in data systems and IoT-enabled storage, we keep our partners ahead of coming mandates without disrupting their workflows. This forward-thinking approach springs directly from firsthand involvement in regulatory conferences, process troubleshooting, and on-site inspections, not just scanning industry newsletters.

    Supply chain resiliency came into sharp focus during global disruptions. As manufacturers, we led efforts to diversify raw material sources and maintain buffer inventories, guided not by spreadsheets alone but by lessons from past shortages. Customers trust us to signal potential delays early and keep hard-won transparency at the center of every discussion.

    Looking Forward: Collaboration and Mutual Improvement

    Our experience tells us that true reliability with specialty intermediates like 2,5-Dichloro-P-Xylene grows out of ongoing, technical partnerships—not one-way “supply” transactions. We prioritize open lines for technical issues, emergency needs, and field troubleshooting. Every product adaptation, specification tweak, or new packaging form traces back to a real use case or operational challenge shared by someone handling actual material, not just theory from a brochure.

    As we move further into a landscape demanding both technical detail and open communication, we see every lot of 2,5-Dichloro-P-Xylene as a building block for mutual trust. Our customers’ day-to-day efficiency and product quality depend on more than a commodity transaction. Drawing on years of supply chain, lab-scale, and high-volume production experience, we supply more than just a chemical; we offer confidence built up lot after lot, shipment after shipment, based on practical understanding and direct collaboration.