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2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone

    • Product Name 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone
    • Alias Tenox 6
    • Einecs 226-407-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    863231

    Chemicalname 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone
    Synonym 2,5-Di-tert-octylhydroquinone
    Molecularformula C26H46O2
    Molarmass 390.64 g/mol
    Casnumber 61827-42-7
    Appearance White to off-white solid
    Solubility Insoluble in water, soluble in organic solvents
    Meltingpoint 72-74°C
    Usage Antioxidant in polymers and plastics
    Storageconditions Store in a cool, dry place away from light and moisture
    Stability Stable under normal conditions
    Density Approx. 1.02 g/cm³
    Ec Number 263-889-6

    As an accredited 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100g amber glass bottle with a screw cap, labeled with chemical name, purity, hazard warnings, and manufacturer information.
    Shipping 2,5-Bis(1,1,3,3-Tetramethylbutyl)hydroquinone is shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. It should be handled as a chemical hazard, often classified under "environmentally hazardous substance." Transport must comply with local and international regulations, and proper labeling, documentation, and safety precautions are required during shipping.
    Storage 2,5-Bis(1,1,3,3-Tetramethylbutyl)hydroquinone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as oxidizing agents. Keep out of direct sunlight and sources of ignition. Store at room temperature and protect from moisture. Ensure proper labeling and follow standard chemical hygiene practices when handling and storing this material.
    Application of 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone

    Applications of 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone in Industrial Manufacturing

    2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone serves as a specialized intermediate and functional additive in several chemical sectors, supporting manufacturers' requirements for process stability, product protection, and regulatory conformity. Below are core industrial applications with process, compliance, and specification details based on direct manufacturing use.

    1. Polymerization Inhibitor in Styrene Monomer Production

    This compound functions as a non-staining polymerization inhibitor in styrene monomer manufacturing, particularly during storage and transportation. Our technical team configures dosage based on monomer purity, storage duration, and temperature variance in customer operations. The material provides prolonged inhibition effect without causing tint or residue, essential for high-grade polymer feedstocks. Extensive QC analysis aligns with pipeline transfer schedules and heat management systems at polymerization plants.

    Industry compliance standards

    • ASTM D2827: Standard Specification for Styrene Monomer (Polymer Grade)
    • REACH Regulation (EC) No 1907/2006 compliant for handling/usage
    • ISO 9001:2015 Quality Management System implemented in batch release
    • Shipping and storage conform to IMDG/ADR guidelines for monomer stabilization chemicals

    Typical usage ratio

    • 5–50 ppm depending on storage time, monomer purity, and expected temperature; QC lab analyses inhibitor depletion to adjust dosage during storage

    Downstream process integration

    • Dosed post-distillation in monomer storage tanks and tank trucks
    • Continuous or batchwise addition monitored by in-line sensors
    • Compatible with downstream polymerization processes; scavenging step used if required in high-spec polystyrene resin production
    • Sampling plans verify polymerization prevention over transport duration

    Final product types

    • High-impact polystyrene (HIPS)
    • General purpose polystyrene (GPPS)
    • Expanded polystyrene (EPS) beads
    • Copolymers utilizing styrene as a core monomer

    2. Antioxidant in Synthetic Lubricant Manufacturing

    Our manufacturing facilities supply this hydroquinone derivative as a secondary antioxidant for compounded synthetic lubricants, especially in high-temperature industrial and automotive formulations. It scavenges peroxyl radicals and decomposes hydroperoxides formed during base oil oxidation. Our application engineers review lube blending schedules and base oil chemistries to guide precise addition points, supporting long drain intervals and resistance to thermal degradation.

    Industry compliance standards

    • API SN Plus and ILSAC GF-5/6 standards for lube oils
    • ACEA C-series regulations for heavy-duty lubricants
    • ISO 21469: Safety of Machinery-Lubricants with Incidental Product Contact
    • Blending plant compliance with NSF certification when required for food-grade lubricants

    Typical usage ratio

    • 0.01–0.2% by weight in finished base oils and lube blends; optimization based on antioxidant package composition and thermal stability trials

    Downstream process integration

    • Added during base oil blending in lube compounding kettles before final filtration
    • Adjusted in multi-component antioxidant systems to balance phenolic, aminic, and sulfur-containing stabilizers
    • Quality checks performed using accelerated oxidation tests (e.g. Rotating Pressure Vessel Oxidation Test)
    • Integrated dosage logs aligned with digital batch management systems

    Final product types

    • Polyalphaolefin (PAO) based automotive lubricants
    • Synthetic compressor oils
    • Industrial gear oils
    • White mineral oil blends with high oxidation stability

    3. Stabilizer in Polyurethane Foams for Automotive Applications

    Our customers in the automotive supply chain incorporate this material as a stabilizer to protect isocyanate and polyol blends from premature oxidative degradation during PU foam block manufacturing. It assists in maintaining consistent cell structure and physical properties in molded and flexible foam products subject to thermal cycling in vehicle interiors. We review customer process parameters and foam formulations seasonally to guide correct stab addition and ensure compliance with strict VOC standards.

    Industry compliance standards

    • ISO 9001 and IATF 16949 quality systems for automotive supplier plants
    • OEM-specific supplier specifications (e.g. VW TL 52877, GM GMW14124A)
    • REACH registration for use in foam intermediates
    • Complies with Japan Polyurethane Industry Association emission and safety guidelines

    Typical usage ratio

    • 0.05–0.15% by weight in combined polyol and isocyanate components; modification based on foam density and open cell/closed cell configurations

    Downstream process integration

    • Pre-blended into polyol component prior to metering in foam lines
    • Dosed by automated gravimetric feeders for consistent distribution in high-throughput block lines
    • QC teams monitor oxidative stability and cell structure post-curing
    • Residual stabilizer checked at off-line QA for compliance prior to final foam cutting or molding

    Final product types

    • Automotive seat foams
    • Headliner panels
    • Tactile instrument panel overlays
    • NVH (Noise Vibration Harshness) foams for vehicle interiors

    4. Inhibitor in Acrylic Acid and Ester Production

    Producers in the acrylics chain utilize this hydroquinone derivative as a process inhibitor in liquid acrylic acid and acrylate esters. We advise optimal integration to protect monomers against runaway polymerization during storage and continuous transfer. Production reliability and end product clarity depend on precise inhibitor dosing tracked by our supply management and QA teams. The inhibitor’s high thermal and UV stability aligns well with bulk storage and tank farm operations in chemical parks.

    Industry compliance standards

    • OECD SIDS for Acrylic Acid and Esters
    • ISO 14001 environmental management in monomer storage operations
    • US EPA TSCA regulations for inhibitor substances in monomer logistics
    • GHS (Globally Harmonized System) compliance for hazard labeling and documentation

    Typical usage ratio

    • 10–100 ppm depending on monomer grade, anticipated storage/transfer time, transport temperature, and downstream customer shipping requirements

    Downstream process integration

    • Dosed in feed tanks post-distillation or upon offloading from railcars and tanker trucks
    • Inline injection pumps meter inhibitor prior to bulk storage
    • QA teams perform inhibitor residue checks pre-shipment
    • Can be removed in purification steps if required for specialty polymer grades

    Final product types

    • Superabsorbent polymers (SAP) for hygiene products
    • Adhesive raw materials (e.g., acrylic PSA)
    • Acrylic surface coatings
    • Rheology modifiers for paint and construction chemicals
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    Certification & Compliance
    More Introduction

    Understanding 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone: Its Value and Role in Industry

    Introduction to Our Product

    At our manufacturing plant, every batch of 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone draws on years of hands-on experience working with alkylated hydroquinones. Our chemists and process engineers have spent countless shifts making sure product consistency meets the right mark for downstream users. This molecule, also known in the industry as a specialty antioxidant, has proven its worth in applications demanding strong resistance against oxidative degradation. The production steps involve careful handling of both hydroquinone and the bulky tetramethylbutyl groups to yield a product that can withstand rigorous processing and storage conditions. With each lot, plant technicians monitor purity and color, both of which can impact function in real-world applications.

    What Sets This Molecule Apart

    Our facility does not just churn out another hydroquinone derivative; we focus on a kind that brings bulky, branched alkyl substituents into play. This structural choice gives 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone a distinct character. Compared with standard hydroquinone, the extra steric hindrance delays the reaction with oxygen. When our customers blend it into plastics or synthetic rubbers, they see a concrete improvement in product shelf life and color stability. Some of our long-standing partners report that certain polyolefin compounds last months longer under accelerated aging because of the unique antioxidant resilience this molecule brings.

    People sometimes ask why not just use a simpler hydroquinone. Our plant crews have looked at that comparison for years. Ordinary hydroquinone or even tert-butyl hydroquinone (TBHQ) often falls short in high-temperature environments, especially under long-term thermal stress. It comes down to the molecular structure. The twin tetramethylbutyl groups on the 2,5 positions don't just take up space; they shield the reactive aromatic core. That means radicals generated during polymer processing have a harder time reaching and breaking down the antioxidant, so it keeps working longer. This leads to real, quantifiable improvements in the final product's resistance to yellowing, embrittlement, and loss of physical properties.

    Supply consistency matters for formulators who need this antioxidant. Our production campaign runs stable processes with controlled feeds and reaction kinetics, targeting impurity levels well below typical industry limits. We constantly tune our vacuum distillation setup to avoid by-product formation. As a manufacturer, we know from experience that even minor deviations in isomer content or color can snowball into problems during compound molding. Materials prone to visual defects or poor oxidative resistance increase costs all the way down the supply chain.

    Specifications Backed by Practical Know-How

    In our quality lab, we keep testing simple but thorough. Visual clarity, HPLC purity, and melt point stay at the core of our checks. Melt point for 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone falls within a narrow band, ensuring easy incorporation into diverse matrices without risk of uneven dispersion. Purity, measured by both HPLC and GC, consistently runs above 99%. We feed this antioxidant into high-shear mixers and extrusion lines ourselves, which helps refine both the manufacturing recipe and the finished product’s form. This kind of direct industrial use forms the backbone of all our process improvement meetings.

    Our product comes in granules that resist caking through typical warehouse humidity swings. This means operators in compounding plants can dose straight from the drum without battling bridging or dusting problems. We also tailor the mesh size to ensure that fine powders don’t blow off conveyors, clogging lines or causing operator headaches. Over a decade, we've learned that the small details in particle sizing lead to big payoffs in plant reliability and throughput.

    Key Application Areas: Protecting End-Use Materials

    Across industries, the need for robust antioxidants keeps growing. High-performance polyolefins, ABS, polystyrene, and rubber blends all benefit from antioxidants that fight thermal and oxidative decay. Our 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone withstands harsh extrusion and molding conditions without breaking down. Plastics processors come to us after testing other antioxidants that faded or yellowed under UV. For cable insulation, wire coatings, and household appliances, this molecule helps minimize breakdown during both process and service life.

    Some of our customers have put our antioxidant to work in food-contact applications where regulations demand careful review of chemical stability. We supply material with full traceability—because regulatory teams need confidence that every lot matches the last, both in purity and absence of unwanted by-products. Certificates of analysis come from people who actually process the compound themselves, not just third-party marketers. If a customer ever flags an outlier, our field engineers can walk the plant floor to check blending and formulation right at the extruder hopper.

    Paints, coatings, and adhesives often run at elevated temperatures or store for long periods before use. Standard antioxidants lose steam in these conditions, leading to color drift and performance losses. By integrating our molecule, manufacturers have reported longer pot life, better color fastness, and improved appearance. Based on trial records, we've seen batches of white paint resist yellowing for months longer when protected with this antioxidant, compared to analogues with just one tert-butyl group or none at all.

    Beyond Basics: Meeting Challenges in Processing

    Anyone running a plastics or rubber compounding plant learns the pitfalls of fine-tuning additive packages. Too much volatility in antioxidant performance leads to rework, scrap, or warranty claims. Over the years, our process teams have set up collaborative troubleshooting with customers. Where a melt viscosity spike shows up, or color stability drops off after extrusion, we're on hand to tweak both our synthesis route and recommendations for blend ratios. Production experts on our staff are used to quick-turn sampling and real-time customer feedback, which accelerates both problem-solving and recipe improvements.

    Sometimes suppliers push “generic” grades of hydroquinones, claiming broad equivalence. Many processors have found the hard way that impurity levels, particle sizing, and batch-to-batch consistency swing too widely. Off-grade batches can jam feeders, introduce specks, or catalyze side reactions in sensitive formulations. Our strategy—constant production oversight, regular cross-checks between synthesis and application labs, and ongoing feedback from industry partners—keeps quality variance to a minimum. Regulars in polymer compounding rely on this stability rather than switch between shifting grades that create unpredictability.

    Regulatory Considerations and Traceability

    We have worked closely with both domestic and international regulators. Our records for each batch of 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone go back years, supported by in-process controls that track every input and operational variable. Auditors can review our line for GMP compliance, and clients can get data backed by original run sheets. Our internal training stresses the importance of traceability, because a recall or regulatory check-up is much more manageable when records match product on the floor.

    For plastics intended for contact with food or medical use, our customers often face steep regulatory hurdles. We support them with detailed impurity profiles and migration studies, drawing on both our own test results and qualified third-party labs. This direct engagement saves a lot of late-stage surprises—nobody wants to rerun food safety approvals because of incomplete chemical dossiers or missing impurity data. Every time a customer completes a regulatory submission based on our product, it teaches us a little more about the practical realities of compliance and documentation.

    Differences from Other Hydroquinone Derivatives

    The antioxidant lineup on the market carries plenty of options: plain hydroquinone, TBHQ, 2,5-di-tert-butylhydroquinone, and more. What sets our variant apart is the space-filling tetramethylbutyl groups that protect the core hydroquinone. In our hands-on trials, this difference isn’t subtle. TBHQ and similar molecules work for moderate-temperature applications but lose performance in harsher polymer or elastomer processes. End-users in coatings and engineering plastics who moved from basic TBHQ or non-alkylated hydroquinones over to this product routinely report less discoloration, longer shelf life, and higher resistance to UV stress.

    Some antioxidant users asked about cost-effectiveness compared to standard options. From our own benchmarking and feedback, the price-per-unit-performance tips in favor of our specialized hydroquinone, especially where product lifetime or process repeatability deliver value downstream. In higher-spec applications, a failed antioxidant is worse than spending a little more upfront to guarantee end-use reliability.

    Another nuance is the impact on process design. Basic hydroquinone and related compounds can volatilize, darken, or even catalyze unintended polymerization under the wrong conditions. Our version shrugs off high temperatures without off-gassing or discoloration, translating into simpler plant cleanup and less risk of cross-contamination between production runs. These practical differences only become obvious on the plant floor, where consistent machine uptime and fewer off-spec lots directly affect the bottom line.

    Storage behavior also differs. Over years of handling, we have observed that non-alkylated hydroquinones can transform under basic warehouse conditions, forming color bodies and sticky residues. The added bulk of the tetramethylbutyl groups in our compound helps it remain free-flowing and less prone to oxidation on contact with air or moisture. Our packaging crews routinely check for caking, compared to alternative antioxidants, and have found far less intervention needed to keep the material dry and usable.

    Real-World Feedback and Continuous Improvement

    End-users from plastics, coatings, and rubber plants come to us with stories from their own lines. Sometimes, a processor notices a batch holds up better on color through eight-hour extrusions. Another reports smoother mixing and fewer shutdowns due to additive separation. We don’t just collect these anecdotes—we use them. Our technical teams invite long-term partners to bring back samples, troubleshoot problems, and figure out whether it’s grade selection, pre-mix handling, or possible machine factors affecting results.

    The strongest insights come from direct plant trials. Years ago, after field-testing our hydroquinone alongside a leading TBHQ product in automotive plastics, the customer logged double the color retention at their standard processing temperatures. This moved the choice from a speculative tweak to a linewide switch. Each new application teaches us more—wide-scale cable insulation production, for instance, has shown that our antioxidant helps maintain dielectric properties longer, reducing the risk of insulation failure in electrical systems.

    From food-contact films to robust industrial sealants, the same attention to detail in our antioxidant’s production means less risk of line trouble, recalls, or competitive failures. By staying close to feedback loops—regular meetings with compounders, line operators, and formulation chemists—we keep improving both the product and how it fits into real-world processes.

    Challenges in Upstream Manufacturing

    Batch manufacturing of alkylated hydroquinones at an industrial scale brings unique obstacles. Raw material handling needs strict control to avoid introducing by-products. Our synthesis reactors run with fine-tuned temperature and pH settings, monitored by operators who recognize even subtle shifts in color or viscosity. Utilities, such as cooling water and inert gas systems, play a silent but essential role. Any shortfall can cause side reactions and unwanted impurity patterns.

    We don’t just scale up textbook chemistry. Each large batch brings lessons in risk management and process optimization. Reactor fouling from polymerization by-products prompted us years ago to upgrade our cleaning protocols and switch to higher-purity solvents in the early synthesis stages. These hands-on refinements mean fewer contamination events and lower operator risk overall—many of these changes grew from listening to those who run the lines daily.

    Even with high automation, batch-to-batch attention yields the best outcome. Regular audits, rapid analytical turnaround, and accessible operator dashboards keep the production curve smooth. Whenever an abnormality shows up—a shift in melt point, a slight off-color in the sight glass—plants that synthesize on-site catch these variances early. End-users never see a difference; the control happens upstream.

    Sustainability Points and Responsible Operations

    Manufacturing specialty antioxidants means managing environmental impact. Over the years, we shifted to solvents with lower VOC emissions, tighter effluent controls, and recycling streams where possible. The move to closed-system transfer for volatile reagents cut plant emissions and improved worker safety. On-site teams have cut waste through improved filtration and solvent recovery, giving both environmental and cost benefits.

    Raw feedstock usage now runs at higher efficiency, assisted by better analytics and plant scheduling. Less off-spec product also means less landfill waste and downstream clean-up. Worker involvement in plant safety committees brings small changes—improved PPE, better air monitoring, streamlined handling instructions—that collectively keep people safer and processes steadier. By feeding back environmental data and blending it with operational learnings, we improve the environmental profile with every campaign.

    Sustainability also means transparency. Customers want clear documentation on supply chain origin, carbon footprint, and chemical traceability. We support that by recording every input, batch modification, and emission metric, giving customers credible documentation when preparing their own sustainability statements.

    Tips for Efficient Use in Commercial Operations

    For compounders and processors, a few core principles maximize the value from this antioxidant. Controlled pre-mixing ensures even distribution through polymer blends. Avoiding excessive moisture during blending preserves both antioxidant action and product free-flowing properties. Users often start at 0.05 to 0.5 percent by weight, tuning the ratio after performance trials in their target application.

    Many of our partners have reduced downtime by switching to our consistent particle size. High-speed feeding systems run more smoothly when additives resist caking, bridging, and static build-up. Our plant crews help develop customized feeding solutions and troubleshoot dispensing problems. In multi-additive systems, it pays to test compatibility in staged trials, especially to confirm physical and chemical stability of the masterbatch. 

    Overdosing adds no further benefit in most formulations. By running comparative extrusion trials, most teams find the optimal point quickly—balancing improved shelf life or color retention against cost and ingredient load. The goal for us as a manufacturer is to share insights from earlier trials, so compounders or coating makers avoid repeating the same expensive troubleshooting rounds.

    Conclusion: The Manufacturer’s Perspective

    From the earliest small-scale trials to today’s ton-scale campaigns, our approach to 2,5-Bis(1,1,3,3-Tetramethylbutyl)Hydroquinone draws directly from plant floor experience. The chemical’s specialized structure offers more than just theoretical value—every process tweak, storage protocol, and blending insight has been shaped by people actually running the equipment. Through ongoing feedback, technical collaboration, and a focus on both output quality and environmental responsibility, we see this molecule’s role expanding wherever long service and process reliability matter. Customers depend on more than just guaranteed supply—they value the know-how that comes from hands-on manufacturing, continuous improvement, and a direct line between what’s made at the reactor and what performs on the job.